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Items: 1 to 50 of 71

1.

JDP2 and ATF3 deficiencies dampen maladaptive cardiac remodeling and preserve cardiac function.

Kalfon R, Friedman T, Eliachar S, Shofti R, Haas T, Koren L, Moskovitz JD, Hai T, Aronheim A.

PLoS One. 2019 Feb 28;14(2):e0213081. doi: 10.1371/journal.pone.0213081. eCollection 2019.

2.

ATF3 and JDP2 deficiency in cancer associated fibroblasts promotes tumor growth via SDF-1 transcription.

Avraham S, Korin B, Aviram S, Shechter D, Shaked Y, Aronheim A.

Oncogene. 2019 May;38(20):3812-3823. doi: 10.1038/s41388-019-0692-y. Epub 2019 Jan 22.

3.

WDR62 mediates TNFα-dependent JNK activation via TRAF2-MLK3 axis.

Prinz E, Aviram S, Aronheim A.

Mol Biol Cell. 2018 Oct 1;29(20):2470-2480. doi: 10.1091/mbc.E17-08-0504. Epub 2018 Aug 9.

4.

The Ras Recruitment System (RRS) for the Identification and Characterization of Protein-Protein Interactions.

Aronheim A.

Methods Mol Biol. 2018;1794:61-73. doi: 10.1007/978-1-4939-7871-7_5.

PMID:
29855951
5.

JDP2 and ATF3 - bZIP repressors in cardiac remodeling.

Kalfon R, Friedman T, Aronheim A.

Int J Cardiol. 2018 Apr 15;257:228. doi: 10.1016/j.ijcard.2017.12.099. No abstract available.

PMID:
29506701
6.

Dimerization of the adaptor Gads facilitates antigen receptor signaling by promoting the cooperative binding of Gads to the adaptor LAT.

Sukenik S, Frushicheva MP, Waknin-Lellouche C, Hallumi E, Ifrach T, Shalah R, Beach D, Avidan R, Oz I, Libman E, Aronheim A, Lewinson O, Yablonski D.

Sci Signal. 2017 Sep 26;10(498). pii: eaal1482. doi: 10.1126/scisignal.aal1482.

PMID:
28951535
7.

c-Jun dimerization protein 2 (JDP2) deficiency promotes cardiac hypertrophy and dysfunction in response to pressure overload.

Kalfon R, Haas T, Shofti R, Moskovitz JD, Schwartz O, Suss-Toby E, Aronheim A.

Int J Cardiol. 2017 Dec 15;249:357-363. doi: 10.1016/j.ijcard.2017.08.074. Epub 2017 Sep 6. No abstract available.

PMID:
28893429
8.

Activating Transcription 3's role in cardiac remodeling.

Kalfon R, Koren L, Aronheim A.

Int J Cardiol. 2017 Sep 1;242:46. doi: 10.1016/j.ijcard.2017.04.031. No abstract available.

PMID:
28619348
9.

ATF3 expression in cardiomyocytes preserves homeostasis in the heart and controls peripheral glucose tolerance.

Kalfon R, Koren L, Aviram S, Schwartz O, Hai T, Aronheim A.

Cardiovasc Res. 2017 Feb;113(2):134-146. doi: 10.1093/cvr/cvw228. Epub 2016 Nov 7.

PMID:
28082453
10.

ATF3, a novel cardiac therapeutic target: Beneficial or harmful?

Kalfon R, Koren L, Aronheim A.

Int J Cardiol. 2017 May 1;234:124. doi: 10.1016/j.ijcard.2017.01.027. Epub 2017 Jan 5. No abstract available.

PMID:
28082095
11.

The cardiac maladaptive ATF3-dependent cross-talk between cardiomyocytes and macrophages is mediated by the IFNγ-CXCL10-CXCR3 axis.

Koren L, Barash U, Zohar Y, Karin N, Aronheim A.

Int J Cardiol. 2017 Feb 1;228:394-400. doi: 10.1016/j.ijcard.2016.11.159. Epub 2016 Nov 10.

PMID:
27870968
12.

Heparanase is required for activation and function of macrophages.

Gutter-Kapon L, Alishekevitz D, Shaked Y, Li JP, Aronheim A, Ilan N, Vlodavsky I.

Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):E7808-E7817. Epub 2016 Nov 14.

13.

Host JDP2 expression in the bone marrow contributes to metastatic spread.

Barbarov Y, Timaner M, Alishekevitz D, Hai T, Yokoyama KK, Shaked Y, Aronheim A.

Oncotarget. 2015 Nov 10;6(35):37737-49. doi: 10.18632/oncotarget.5648.

14.

Response letter: "ATF3: A promoter or inhibitor of cardiac maladaptive remodeling".

Koren L, Shaked Y, Aronheim A.

Int J Cardiol. 2015 Dec 15;201:692. doi: 10.1016/j.ijcard.2015.08.169. Epub 2015 Aug 28. No abstract available.

PMID:
26374759
15.

ATF3-dependent cross-talk between cardiomyocytes and macrophages promotes cardiac maladaptive remodeling.

Koren L, Alishekevitz D, Elhanani O, Nevelsky A, Hai T, Kehat I, Shaked Y, Aronheim A.

Int J Cardiol. 2015 Nov 1;198:232-40. doi: 10.1016/j.ijcard.2015.06.099. Epub 2015 Jul 9.

PMID:
26201690
16.

Correction: Adult Cardiac Expression of the Activating Transcription Factor 3, ATF3, Promotes Ventricular Hypertrophy.

Koren L, Elhanani O, Kehat I, Hai T, Aronheim A.

PLoS One. 2013 Sep 19;8(9). doi: 10.1371/annotation/87e2a80b-3ed7-4ef9-96cb-1268d91b6366. eCollection 2013.

17.

Adult cardiac expression of the activating transcription factor 3, ATF3, promotes ventricular hypertrophy.

Koren L, Elhanani O, Kehat I, Hai T, Aronheim A.

PLoS One. 2013 Jul 3;8(7):e68396. doi: 10.1371/journal.pone.0068396. Print 2013. Erratum in: PLoS One. 2013 Sep 19;8(9):.

18.

Inhibition of AP-1 signaling by JDP2 overexpression protects cardiomyocytes against hypertrophy and apoptosis induction.

Hill C, Würfel A, Heger J, Meyering B, Schlüter KD, Weber M, Ferdinandy P, Aronheim A, Schulz R, Euler G.

Cardiovasc Res. 2013 Jul 1;99(1):121-8. doi: 10.1093/cvr/cvt094. Epub 2013 Apr 23.

PMID:
23612584
19.

Identification and analysis of a novel dimerization domain shared by various members of c-Jun N-terminal kinase (JNK) scaffold proteins.

Cohen-Katsenelson K, Wasserman T, Darlyuk-Saadon I, Rabner A, Glaser F, Aronheim A.

J Biol Chem. 2013 Mar 8;288(10):7294-304. doi: 10.1074/jbc.M112.422055. Epub 2013 Jan 22.

20.

The bZIP repressor proteins, c-Jun dimerization protein 2 and activating transcription factor 3, recruit multiple HDAC members to the ATF3 promoter.

Darlyuk-Saadon I, Weidenfeld-Baranboim K, Yokoyama KK, Hai T, Aronheim A.

Biochim Biophys Acta. 2012 Nov-Dec;1819(11-12):1142-53. doi: 10.1016/j.bbagrm.2012.09.005. Epub 2012 Sep 16.

21.

Docking interactions of the JNK scaffold protein WDR62.

Cohen-Katsenelson K, Wasserman T, Khateb S, Whitmarsh AJ, Aronheim A.

Biochem J. 2011 Nov 1;439(3):381-90. doi: 10.1042/BJ20110284.

22.

Phosphorylation of JDP2 on threonine-148 by the c-Jun N-terminal kinase targets it for proteosomal degradation.

Weidenfeld-Baranboim K, Koren L, Aronheim A.

Biochem J. 2011 Jun 15;436(3):661-9. doi: 10.1042/BJ20101031.

PMID:
21463260
23.

Angiotensin II signaling up-regulates the immediate early transcription factor ATF3 in the left but not the right atrium.

Hasin T, Elhanani O, Abassi Z, Hai T, Aronheim A.

Basic Res Cardiol. 2011 Mar;106(2):175-87. doi: 10.1007/s00395-010-0145-9. Epub 2010 Dec 30.

24.

The AP-1 repressor protein, JDP2, potentiates hepatocellular carcinoma in mice.

Bitton-Worms K, Pikarsky E, Aronheim A.

Mol Cancer. 2010 Mar 9;9:54. doi: 10.1186/1476-4598-9-54.

25.

A novel c-Jun N-terminal kinase (JNK)-binding protein WDR62 is recruited to stress granules and mediates a nonclassical JNK activation.

Wasserman T, Katsenelson K, Daniliuc S, Hasin T, Choder M, Aronheim A.

Mol Biol Cell. 2010 Jan 1;21(1):117-30. doi: 10.1091/mbc.E09-06-0512. Epub 2009 Nov 12.

26.

The ubiquitously expressed bZIP inhibitor, JDP2, suppresses the transcription of its homologue immediate early gene counterpart, ATF3.

Weidenfeld-Baranboim K, Hasin T, Darlyuk I, Heinrich R, Elhanani O, Pan J, Yokoyama KK, Aronheim A.

Nucleic Acids Res. 2009 Apr;37(7):2194-203. doi: 10.1093/nar/gkp083. Epub 2009 Feb 20.

27.

TRE-dependent transcription activation by JDP2-CHOP10 association.

Weidenfeld-Baranboim K, Bitton-Worms K, Aronheim A.

Nucleic Acids Res. 2008 Jun;36(11):3608-19. doi: 10.1093/nar/gkn268. Epub 2008 May 7.

28.

Autophosphorylation-dependent degradation of Pak1, triggered by the Rho-family GTPase, Chp.

Weisz Hubsman M, Volinsky N, Manser E, Yablonski D, Aronheim A.

Biochem J. 2007 Jun 15;404(3):487-97.

29.
30.

Inhibition of basic leucine zipper transcription is a major mediator of atrial dilatation.

Kehat I, Heinrich R, Ben-Izhak O, Miyazaki H, Gutkind JS, Aronheim A.

Cardiovasc Res. 2006 Jun 1;70(3):543-54. Epub 2006 Mar 6.

PMID:
16631626
31.

RalA interacts with ZONAB in a cell density-dependent manner and regulates its transcriptional activity.

Frankel P, Aronheim A, Kavanagh E, Balda MS, Matter K, Bunney TD, Marshall CJ.

EMBO J. 2005 Jan 12;24(1):54-62. Epub 2004 Dec 9.

32.

Ras signaling pathway for analysis of protein-protein interactions in yeast and mammalian cells.

Aronheim A.

Methods Mol Biol. 2004;250:251-62. No abstract available.

PMID:
14755093
33.

The c-Jun dimerization protein 2 inhibits cell transformation and acts as a tumor suppressor gene.

Heinrich R, Livne E, Ben-Izhak O, Aronheim A.

J Biol Chem. 2004 Feb 13;279(7):5708-15. Epub 2003 Nov 19.

34.

Disruption of transport activity in a D93H mutant thiamine transporter 1, from a Rogers Syndrome family.

Baron D, Assaraf YG, Drori S, Aronheim A.

Eur J Biochem. 2003 Nov;270(22):4469-77.

35.

The prodomain of a secreted hydrophobic mini-protein facilitates its export from the endoplasmic reticulum by hitchhiking on sorting receptors.

Conticello SG, Kowalsman ND, Jacobsen C, Yudkovsky G, Sato K, Elazar Z, Petersen CM, Aronheim A, Fainzilber M.

J Biol Chem. 2003 Jul 18;278(29):26311-4. Epub 2003 May 27.

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41.

Induction of terminal differentiation by the c-Jun dimerization protein JDP2 in C2 myoblasts and rhabdomyosarcoma cells.

Ostrovsky O, Bengal E, Aronheim A.

J Biol Chem. 2002 Oct 18;277(42):40043-54. Epub 2002 Aug 8.

42.

Jun dimerization protein 2 functions as a progesterone receptor N-terminal domain coactivator.

Wardell SE, Boonyaratanakornkit V, Adelman JS, Aronheim A, Edwards DP.

Mol Cell Biol. 2002 Aug;22(15):5451-66.

43.

A novel specific role for I kappa B kinase complex-associated protein in cytosolic stress signaling.

Holmberg C, Katz S, Lerdrup M, Herdegen T, Jäättelä M, Aronheim A, Kallunki T.

J Biol Chem. 2002 Aug 30;277(35):31918-28. Epub 2002 Jun 10.

44.

The AP-1 repressor, JDP2, is a bona fide substrate for the c-Jun N-terminal kinase.

Katz S, Heinrich R, Aronheim A.

FEBS Lett. 2001 Oct 12;506(3):196-200.

45.

Membrane recruitment systems for analysis of protein-protein interactions.

Aronheim A.

Methods Mol Biol. 2001;177:319-28. No abstract available.

PMID:
11530615
46.
47.

HBV X protein targets HIV Tat-binding protein 1.

Barak O, Aronheim A, Shaul Y.

Virology. 2001 Apr 25;283(1):110-20.

48.

Ras signaling pathway for analysis of protein-protein interactions.

Aronheim A.

Methods Enzymol. 2001;332:260-70. No abstract available.

PMID:
11305102
49.

AP-1 repressor protein JDP-2: inhibition of UV-mediated apoptosis through p53 down-regulation.

Piu F, Aronheim A, Katz S, Karin M.

Mol Cell Biol. 2001 May;21(9):3012-24.

50.

A novel approach for the identification of protein-protein interaction with integral membrane proteins.

Hubsman M, Yudkovsky G, Aronheim A.

Nucleic Acids Res. 2001 Feb 15;29(4):E18.

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