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Clinical and morphologic predictors of outcome in older aplastic anemia patients treated with eltrombopag.

Fattizzo B, Kulasekararaj AG, Hill A, Benson-Quarm N, Griffin M, Munir T, Arnold L, Riley K, Ireland R, De Lavallade H, Potter V, Consonni D, Hillmen P, Mufti GJ, Barcellini W, Marsh JCW.

Haematologica. 2019 Mar 19. pii: haematol.2019.216374. doi: 10.3324/haematol.2019.216374. [Epub ahead of print]


Response to Wolfe. Letter to the Editor, "Fibromyalgia Criteria".

Arnold LM, Bennett RM, Crofford LJ, Dean LE, Clauw DJ, Goldenberg DL, Fitzcharles MA, Paiva ES, Staud R, Sarzi-Puttini P, Buskila D, Macfarlane GJ.

J Pain. 2019 Feb 26. pii: S1526-5900(19)30089-6. doi: 10.1016/j.jpain.2019.02.003. [Epub ahead of print] No abstract available.


MIDD0301 - A first-in-class anti-inflammatory asthma drug targets GABAA receptors without causing systemic immune suppression.

Zahn NM, Huber AT, Mikulsky BN, Stepanski ME, Kehoe AS, Li G, Schussman M, Rashid Roni MS, Kodali R, Cook JM, Stafford DC, Steeber DA, Arnold LA.

Basic Clin Pharmacol Toxicol. 2019 Jan 29. doi: 10.1111/bcpt.13206. [Epub ahead of print]


Design and Evaluation of Heterobivalent PAR1-PAR2 Ligands as Antagonists of Calcium Mobilization.

Majewski MW, Gandhi DM, Rosas R Jr, Kodali R, Arnold LA, Dockendorff C.

ACS Med Chem Lett. 2018 Dec 3;10(1):121-126. doi: 10.1021/acsmedchemlett.8b00538. eCollection 2019 Jan 10.


Alternative binding sites at the vitamin D receptor and their ligands.

Mutchie TR, Yu OB, Di Milo ES, Arnold LA.

Mol Cell Endocrinol. 2019 Apr 5;485:1-8. doi: 10.1016/j.mce.2019.01.011. Epub 2019 Jan 14. Review.


Health Professional Training and Capacity Strengthening Through International Academic Partnerships: The First Five Years of the Human Resources for Health Program in Rwanda.

Cancedda C, Cotton P, Shema J, Rulisa S, Riviello R, Adams LV, Farmer PE, Kagwiza JN, Kyamanywa P, Mukamana D, Mumena C, Tumusiime DK, Mukashyaka L, Ndenga E, Twagirumugabe T, Mukara KB, Dusabejambo V, Walker TD, Nkusi E, Bazzett-Matabele L, Butera A, Rugwizangoga B, Kabayiza JC, Kanyandekwe S, Kalisa L, Ntirenganya F, Dixson J, Rogo T, McCall N, Corden M, Wong R, Mukeshimana M, Gatarayiha A, Ntagungira EK, Yaman A, Musabeyezu J, Sliney A, Nuthulaganti T, Kernan M, Okwi P, Rhatigan J, Barrow J, Wilson K, Levine AC, Reece R, Koster M, Moresky RT, O'Flaherty JE, Palumbo PE, Ginwalla R, Binanay CA, Thielman N, Relf M, Wright R, Hill M, Chyun D, Klar RT, McCreary LL, Hughes TL, Moen M, Meeks V, Barrows B, Durieux ME, McClain CD, Bunts A, Calland FJ, Hedt-Gauthier B, Milner D, Raviola G, Smith SE, Tuteja M, Magriples U, Rastegar A, Arnold L, Magaziner I, Binagwaho A.

Int J Health Policy Manag. 2018 Aug 6;7(11):1024-1039. doi: 10.15171/ijhpm.2018.61.


Attendance and Engagement in Parent Training Predict Child Behavioral Outcomes in Children Pharmacologically Treated for Attention-Deficit/Hyperactivity Disorder and Severe Aggression.

Joseph HM, Farmer C, Kipp H, Kolko D, Aman M, McGinley J, Arnold LE, Gadow KD, Findling RL, Molina BSG.

J Child Adolesc Psychopharmacol. 2019 Mar;29(2):90-99. doi: 10.1089/cap.2018.0119. Epub 2018 Dec 28.


Histopathology re-examination of the NTP toxicity/carcinogenicity studies of tert-butyl alcohol to identify renal tumor and toxicity modes of action.

Hard GC, Cohen SM, Ma J, Yu F, Arnold LL, Banton MI.

Regul Toxicol Pharmacol. 2019 Mar;102:65-73. doi: 10.1016/j.yrtph.2018.12.011. Epub 2018 Dec 24.


Palliative care initiation in pediatric oncology patients: A systematic review.

Cheng BT, Rost M, De Clercq E, Arnold L, Elger BS, Wangmo T.

Cancer Med. 2019 Jan;8(1):3-12. doi: 10.1002/cam4.1907. Epub 2018 Dec 7. Review.


A novel GABAA receptor ligand MIDD0301 with limited blood-brain barrier penetration relaxes airway smooth muscle ex vivo and in vivo.

Yocum GT, Perez-Zoghbi JF, Danielsson J, Kuforiji AS, Zhang Y, Li G, Rashid Roni MS, Kodali R, Stafford DC, Arnold LA, Cook JM, Emala CW Sr.

Am J Physiol Lung Cell Mol Physiol. 2019 Feb 1;316(2):L385-L390. doi: 10.1152/ajplung.00356.2018. Epub 2018 Nov 29.


Bullous Diabeticorum.

Arnold L, Vennard KC, Gilbert MP.

J Am Osteopath Assoc. 2018 Dec 1;118(12):832. doi: 10.7556/jaoa.2018.178. No abstract available.


Obtaining contextually relevant geographic data using Facebook recruitment in public health studies.

Nelson EJ, Loux T, Arnold LD, Siddiqui ST, Schootman M.

Health Place. 2019 Jan;55:37-42. doi: 10.1016/j.healthplace.2018.11.002. Epub 2018 Nov 19.


AMPK Activation Regulates LTBP4-Dependent TGF-β1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy.

Juban G, Saclier M, Yacoub-Youssef H, Kernou A, Arnold L, Boisson C, Ben Larbi S, Magnan M, Cuvellier S, Théret M, Petrof BJ, Desguerre I, Gondin J, Mounier R, Chazaud B.

Cell Rep. 2018 Nov 20;25(8):2163-2176.e6. doi: 10.1016/j.celrep.2018.10.077.


AAPT Diagnostic Criteria for Fibromyalgia.

Arnold LM, Bennett RM, Crofford LJ, Dean LE, Clauw DJ, Goldenberg DL, Fitzcharles MA, Paiva ES, Staud R, Sarzi-Puttini P, Buskila D, Macfarlane GJ.

J Pain. 2018 Nov 16. pii: S1526-5900(18)30832-0. doi: 10.1016/j.jpain.2018.10.008. [Epub ahead of print] Review.


Associations between Parental Psychopathology and Sexual Behavior in an Outpatient Psychiatric Sample.

Black SR, Seager I, Meers MR, Arnold LE, Birmaher B, Findling RL, Horwitz SM, Youngstrom EA, Fristad MA.

J Clin Child Adolesc Psychol. 2018 Oct 30:1-10. doi: 10.1080/15374416.2018.1514614. [Epub ahead of print]


The association between fetal-stage exposure to the China famine and risk of diabetes mellitus in adulthood: results from the China health and retirement longitudinal study.

Wang Z, Zou Z, Yang Z, Dong Y, Song J, Dong B, Ma J, Arnold L.

BMC Public Health. 2018 Oct 26;18(1):1205. doi: 10.1186/s12889-018-6134-x.


Long-term outcomes of adolescents with juvenile-onset fibromyalgia into adulthood and impact of depressive symptoms on functioning over time.

Kashikar-Zuck S, Cunningham N, Peugh J, Black WR, Nelson S, Lynch-Jordan AM, Pfeiffer M, Tran ST, Ting TV, Arnold LM, Carle A, Noll J, Powers SW, Lovell DJ.

Pain. 2019 Feb;160(2):433-441. doi: 10.1097/j.pain.0000000000001415.


An Integrated Approach to Aggregate Control for Therapeutic Bispecific Antibodies Using an Improved Three Column Mab Platform-Like Purification Process.

Andrade C, Arnold L, Motabar D, Aspelund M, Tang A, Hunter A, Chung WK.

Biotechnol Prog. 2019 Jan;35(1):e2720. doi: 10.1002/btpr.2720. Epub 2018 Oct 17.


Significant hemolysis is not required for thrombosis in paroxysmal nocturnal hemoglobinuria.

Griffin M, Hillmen P, Munir T, Richards S, Arnold L, Riley K, Hill A.

Haematologica. 2019 Mar;104(3):e94-e96. doi: 10.3324/haematol.2018.198846. Epub 2018 Oct 4. No abstract available.


High-level artemisinin-resistance with quinine co-resistance emerges in P. falciparum malaria under in vivo artesunate pressure.

Tyagi RK, Gleeson PJ, Arnold L, Tahar R, Prieur E, Decosterd L, Pérignon JL, Olliaro P, Druilhe P.

BMC Med. 2018 Oct 1;16(1):181. doi: 10.1186/s12916-018-1156-x.


Salivary beta amyloid protein levels are detectable and differentiate patients with Alzheimer's disease dementia from normal controls: preliminary findings.

Sabbagh MN, Shi J, Lee M, Arnold L, Al-Hasan Y, Heim J, McGeer P.

BMC Neurol. 2018 Sep 26;18(1):155. doi: 10.1186/s12883-018-1160-y.


Discovery and Optimization of Novel Hydrogen Peroxide Activated Aromatic Nitrogen Mustard Derivatives as Highly Potent Anticancer Agents.

Chen W, Fan H, Balakrishnan K, Wang Y, Sun H, Fan Y, Gandhi V, Arnold LA, Peng X.

J Med Chem. 2018 Oct 25;61(20):9132-9145. doi: 10.1021/acs.jmedchem.8b00559. Epub 2018 Oct 10.


Predictive utility of childhood diagnosis of ICD-10 hyperkinetic disorder: adult outcomes in the MTA and effect of comorbidity.

Arnold LE, Roy A, Taylor E, Hechtman L, Sibley M, Swanson JM, Mitchell JT, Molina BSG, Rohde LA.

Eur Child Adolesc Psychiatry. 2018 Sep 19. doi: 10.1007/s00787-018-1222-0. [Epub ahead of print]


Testing genetic modifiers of behavior and response to atomoxetine in autism spectrum disorder with ADHD.

Barrie ES, Pinsonneault JK, Sadee W, Hollway JA, Handen BL, Smith T, Arnold LE, Butter E, Hansen-Kiss E, Herman GE, Aman MG.

J Dev Phys Disabil. 2018 Jun;30(3):355-371. doi: 10.1007/s10882-018-9590-4. Epub 2018 Mar 5.


[Methodological Challenges of Prevention Reporting - More to it Than Just Evidence Reporting!]

Starke D, Arnold L, Fertmann R, March S, Moebus S, Terschüren C, Szagun B.

Gesundheitswesen. 2018 Aug;80(8-09):732-740. doi: 10.1055/a-0665-6249. Epub 2018 Sep 3. German.


A Novel, Nonpeptidic, Orally Active Bivalent Inhibitor of Human β-Tryptase.

Giardina SF, Werner DS, Pingle M, Bergstrom DE, Arnold LD, Barany F.

Pharmacology. 2018;102(5-6):233-243. doi: 10.1159/000492078. Epub 2018 Aug 22.


Target-Directed Self-Assembly of Homodimeric Drugs Against β-Tryptase.

Giardina SF, Werner DS, Pingle M, Foreman KW, Bergstrom DE, Arnold LD, Barany F.

ACS Med Chem Lett. 2018 Jul 5;9(8):827-831. doi: 10.1021/acsmedchemlett.8b00204. eCollection 2018 Aug 9.


Potent Antitumor Effects of a Combination of Three Nutraceutical Compounds.

Vishwakarma V, New J, Kumar D, Snyder V, Arnold L, Nissen E, Hu Q, Cheng N, Miller D, Thomas AR, Shnayder Y, Kakarala K, Tsue TT, Girod DA, Thomas SM.

Sci Rep. 2018 Aug 15;8(1):12163. doi: 10.1038/s41598-018-29683-1.


Views of Obesity in Black Women from a Cultural Perspective.

Johnson P, Wesley Y, Arnold L, Greene L.

J Natl Black Nurses Assoc. 2017 Jul;28(1):50-53.


Cancer Stem Cell Metabolism and Potential Therapeutic Targets.

Snyder V, Reed-Newman TC, Arnold L, Thomas SM, Anant S.

Front Oncol. 2018 Jun 5;8:203. doi: 10.3389/fonc.2018.00203. eCollection 2018. Review.


Factors associated with increased risk of suicide among survivors of head and neck cancer: A population-based analysis.

Osazuwa-Peters N, Arnold LD, Loux TM, Varvares MA, Schootman M.

Oral Oncol. 2018 Jun;81:29-34. doi: 10.1016/j.oraloncology.2018.03.017. Epub 2018 Apr 11.


Diffusion imaging markers of bipolar versus general psychopathology risk in youth at-risk.

Versace A, Ladouceur CD, Graur S, Acuff HE, Bonar LK, Monk K, McCaffrey A, Yendiki A, Leemans A, Travis MJ, Diwadkar VA, Holland SK, Sunshine JL, Kowatch RA, Horwitz SM, Frazier TW, Arnold LE, Fristad MA, Youngstrom EA, Findling RL, Goldstein BI, Goldstein T, Axelson D, Birmaher B, Phillips ML.

Neuropsychopharmacology. 2018 Oct;43(11):2212-2220. doi: 10.1038/s41386-018-0083-z. Epub 2018 May 4.


Implementation of Fully Integrated Continuous Antibody Processing: Effects on Productivity and COGm.

Arnold L, Lee K, Rucker-Pezzini J, Lee JH.

Biotechnol J. 2019 Feb;14(2):e1800061. doi: 10.1002/biot.201800061. Epub 2018 May 22.


The Importance of Scrutinizing Emergent ADHD Symptoms in Adults: Response to Chamberlain and Müller.

Sibley MH, Arnold LE, Swanson JM, Kennedy TM, Molina BSG, Hechtman LT, Roy A, Mitchell JT.

Am J Psychiatry. 2018 May 1;175(5):480-481. doi: 10.1176/appi.ajp.2018.17121308r. No abstract available.


Addressing Incomplete Psychiatric Histories in Adult ADHD: Response to Agnew-Blais and Arseneault.

Sibley MH, Arnold LE, Swanson JM, Kennedy TM, Molina BSG, Hechtman LT, Roy A, Mitchell JT.

Am J Psychiatry. 2018 May 1;175(5):482-483. doi: 10.1176/appi.ajp.2018.17111240r. No abstract available.


Clinical Relevance Versus Statistical Significance: Aman and Colleagues Respond to Editorial.

Aman MG, Arnold LE, Barterian JA.

J Am Acad Child Adolesc Psychiatry. 2018 May;57(5):352-353. doi: 10.1016/j.jaac.2017.12.012.


Prevalence of excess body weight and underweight among 26 Chinese ethnic minority children and adolescents in 2014: a cross-sectional observational study.

Dong Y, Zou Z, Yang Z, Wang Z, Yang Y, Ma J, Dong B, Ma Y, Arnold L.

BMC Public Health. 2018 Apr 27;18(1):562. doi: 10.1186/s12889-018-5352-6.


A 1.5-Year Follow-Up of Parent Training and Atomoxetine for Attention-Deficit/Hyperactivity Disorder Symptoms and Noncompliant/Disruptive Behavior in Autism.

Arnold LE, Ober N, Aman MG, Handen B, Smith T, Pan X, Hyman SL, Hollway J, Lecavalier L, Page K, Rice R Jr.

J Child Adolesc Psychopharmacol. 2018 Jun;28(5):322-330. doi: 10.1089/cap.2017.0134. Epub 2018 Apr 25.


Association between the Great China Famine exposure in early life and risk of arthritis in adulthood.

Wang Z, Zou Z, Dong B, Ma J, Arnold L.

J Epidemiol Community Health. 2018 Sep;72(9):790-795. doi: 10.1136/jech-2017-210334. Epub 2018 Apr 21.


Predicting enrollment in two randomized controlled trials of nonpharmacologic interventions for youth with primary mood disorders.

Young AS, Seidenfeld AM, Healy KZ, Arnold LE, Fristad MA.

J Affect Disord. 2018 Aug 1;235:368-373. doi: 10.1016/j.jad.2018.04.024. Epub 2018 Apr 4.


Single pass diafiltration integrated into a fully continuous mAb purification process.

Rucker-Pezzini J, Arnold L, Hill-Byrne K, Sharp T, Avazhanskiy M, Forespring C.

Biotechnol Bioeng. 2018 Aug;115(8):1949-1957. doi: 10.1002/bit.26708. Epub 2018 Apr 27.


A high-throughput screening assay for pyruvate carboxylase.

Wyatt BN, Arnold LA, St Maurice M.

Anal Biochem. 2018 Jun 1;550:90-98. doi: 10.1016/j.ab.2018.04.012. Epub 2018 Apr 12.


Single Pass Diafiltration Integrated into a Fully Continuous mAb Purification Process.

Rucker-Pezzini J, Arnold L, Hill-Byrne K, Sharp T, Avazhanskiy M, Forespring C.

Biotechnol Bioeng. 2018 Apr 12. doi: 10.1002/bit.26608. [Epub ahead of print]


Effects of Metformin on Spatial and Verbal Memory in Children with ASD and Overweight Associated with Atypical Antipsychotic Use.

Aman MG, Hollway JA, Veenstra-VanderWeele J, Handen BL, Sanders KB, Chan J, Macklin E, Arnold LE, Wong T, Newsom C, Hastie Adams R, Marler S, Peleg N, Anagnostou EA.

J Child Adolesc Psychopharmacol. 2018 May;28(4):266-273. doi: 10.1089/cap.2017.0072. Epub 2018 Apr 5.


A Review of Promising Natural Chemopreventive Agents for Head and Neck Cancer.

Crooker K, Aliani R, Ananth M, Arnold L, Anant S, Thomas SM.

Cancer Prev Res (Phila). 2018 Aug;11(8):441-450. doi: 10.1158/1940-6207.CAPR-17-0419. Epub 2018 Mar 30. Review.


A Novel Orally Available Asthma Drug Candidate That Reduces Smooth Muscle Constriction and Inflammation by Targeting GABAA Receptors in the Lung.

Forkuo GS, Nieman AN, Kodali R, Zahn NM, Li G, Rashid Roni MS, Stephen MR, Harris TW, Jahan R, Guthrie ML, Yu OB, Fisher JL, Yocum GT, Emala CW, Steeber DA, Stafford DC, Cook JM, Arnold LA.

Mol Pharm. 2018 May 7;15(5):1766-1777. doi: 10.1021/acs.molpharmaceut.7b01013. Epub 2018 Apr 2.


Physiological Stress Elicits Impaired Left Ventricular Function in Preterm-Born Adults.

Huckstep OJ, Williamson W, Telles F, Burchert H, Bertagnolli M, Herdman C, Arnold L, Smillie R, Mohamed A, Boardman H, McCormick K, Neubauer S, Leeson P, Lewandowski AJ.

J Am Coll Cardiol. 2018 Mar 27;71(12):1347-1356. doi: 10.1016/j.jacc.2018.01.046.


Concurrent treatment of aplastic anemia/paroxysmal nocturnal hemoglobinuria syndrome with immunosuppressive therapy and eculizumab: a UK experience.

Griffin M, Kulasekararaj A, Gandhi S, Munir T, Richards S, Arnold L, Benson-Quarm N, Copeland N, Duggins I, Riley K, Hillmen P, Marsh J, Hill A.

Haematologica. 2018 Aug;103(8):e345-e347. doi: 10.3324/haematol.2017.183046. Epub 2018 Mar 15. No abstract available.


Cigarette Smoking Progression among Young Adults Diagnosed with ADHD in Childhood: A 16-year Longitudinal Study of Children with and without ADHD.

Mitchell JT, Howard AL, Belendiuk KA, Kennedy TM, Stehli A, Swanson JM, Hechtman L, Arnold LE, Hoza B, Vitiello B, Lu B, Kollins SH, Molina BSG.

Nicotine Tob Res. 2018 Mar 12. doi: 10.1093/ntr/nty045. [Epub ahead of print]


Bipolar disorder in youth is associated with increased levels of vitamin D-binding protein.

Petrov B, Aldoori A, James C, Yang K, Algorta GP, Lee A, Zhang L, Lin T, Awadhi RA, Parquette JR, Samogyi A, Arnold LE, Fristad MA, Gracious B, Ziouzenkova O.

Transl Psychiatry. 2018 Mar 13;8(1):61. doi: 10.1038/s41398-018-0109-7.

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