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Synthesis and biological evaluation of calcioic acid.

Yu OB, Mutchie TR, Di Milo ES, Arnold LA.

Steroids. 2019 Nov 5:108536. doi: 10.1016/j.steroids.2019.108536. [Epub ahead of print]


Cotinine, a major nicotine metabolite, induces cell proliferation on urothelium in vitro and in vivo.

Suzuki S, Cohen SM, Arnold LL, Pennington KL, Kato H, Naiki T, Naiki-Ito A, Yamashita Y, Takahashi S.

Toxicology. 2019 Oct 31:152325. doi: 10.1016/j.tox.2019.152325. [Epub ahead of print]


An anthrone-based Kv7.2/7.3 channel blocker with improved properties for the investigation of psychiatric and neurodegenerative disorders.

Porter JD, Vivas O, Weaver CD, Alsafran A, DiMilo E, Arnold LA, Dickson EJ, Dockendorff C.

Bioorg Med Chem Lett. 2019 Dec 1;29(23):126681. doi: 10.1016/j.bmcl.2019.126681. Epub 2019 Sep 14.


Using multilevel regression with poststratification to obtain regional health estimates from a Facebook-recruited sample.

Loux T, Nelson EJ, Arnold LD, Shacham E, Schootman M.

Ann Epidemiol. 2019 Sep 25. pii: S1047-2797(19)30247-9. doi: 10.1016/j.annepidem.2019.09.005. [Epub ahead of print]


Impact of Adverse Childhood Experiences on Oral Health Among Women in the United States: Findings From the Behavioral Risk Factor Surveillance System.

Bosch J, Weaver TL, Arnold LD.

J Interpers Violence. 2019 Oct 29:886260519883872. doi: 10.1177/0886260519883872. [Epub ahead of print]


The role of the innate and adaptive immune response in HPV-associated oropharyngeal squamous cell carcinoma.

Subbarayan RS, Arnold L, Gomez JP, Thomas SM.

Laryngoscope Investig Otolaryngol. 2019 Aug 12;4(5):508-512. doi: 10.1002/lio2.300. eCollection 2019 Oct. Review.


Correction to "A Novel Orally Available Asthma Drug Candidate That Reduces Smooth Muscle Constriction and Inflammation by Targeting GABAA Receptors in the Lung".

Forkuo GS, Nieman AN, Kodali R, Zahn NM, Li G, Roni MSR, Stephen MR, Harris TW, Jahan R, Guthrie ML, Yu OB, Fisher JL, Yocum GT, Emala CW, Steeber DA, Stafford DC, Cook JM, Arnold LA.

Mol Pharm. 2019 Nov 4;16(11):4756. doi: 10.1021/acs.molpharmaceut.9b01053. Epub 2019 Oct 21. No abstract available.


Clinical, cortical thickness and neural activity predictors of future affective lability in youth at risk for bipolar disorder: initial discovery and independent sample replication.

Bertocci MA, Hanford L, Manelis A, Iyengar S, Youngstrom EA, Gill MK, Monk K, Versace A, Bonar L, Bebko G, Ladouceur CD, Perlman SB, Diler R, Horwitz SM, Arnold LE, Hafeman D, Travis MJ, Kowatch R, Holland SK, Fristad MA, Findling RL, Birmaher B, Phillips ML.

Mol Psychiatry. 2018 Oct 19. doi: 10.1038/s41380-018-0273-4. [Epub ahead of print]


Analytical validation of the Target Selector ctDNA platform featuring single copy detection sensitivity for clinically actionable EGFR, BRAF, and KRAS mutations.

Poole JC, Wu SF, Lu TT, Vibat CRT, Pham A, Samuelsz E, Patel M, Chen J, Daher T, Singh VM, Arnold LJ.

PLoS One. 2019 Oct 3;14(10):e0223112. doi: 10.1371/journal.pone.0223112. eCollection 2019.


Mitochondrial lipid droplet formation as a detoxification mechanism to sequester and degrade excessive urothelial membranes.

Liao Y, Tham DKL, Liang FX, Chang J, Wei Y, Reddy SP, Sall J, Ren SJ, Chicote JU, Arnold LL, Hu CA, Romih R, Andrade LR, Rindler MJ, Cohen SM, DeSalle R, Garcia-España A, Ding M, Wu XR, Sun TT.

Mol Biol Cell. 2019 Oct 2:mbcE19050284. doi: 10.1091/mbc.E19-05-0284. [Epub ahead of print]


Development of bipolar disorder and other comorbidity among youth with attention-deficit/hyperactivity disorder.

Arnold LE, Van Meter AR, Fristad MA, Youngstrom EA, Birmaher BB, Findling RL, Horwitz S, Black SR.

J Child Psychol Psychiatry. 2019 Sep 15. doi: 10.1111/jcpp.13122. [Epub ahead of print]


Probiotics for Gastrointestinal Symptoms and Quality of Life in Autism: A Placebo-Controlled Pilot Trial.

Arnold LE, Luna RA, Williams K, Chan J, Parker RA, Wu Q, Hollway JA, Jeffs A, Lu F, Coury DL, Hayes C, Savidge T.

J Child Adolesc Psychopharmacol. 2019 Nov;29(9):659-669. doi: 10.1089/cap.2018.0156. Epub 2019 Aug 30.


Adult substance use as a function of growth in peer use across adolescence and young adulthood in the context of ADHD: Findings from the MTA.

Kennedy TM, Howard AL, Mitchell JT, Hoza B, Arnold LE, Hechtman LT, Swanson JM, Stehli A, Molina BSG.

Addict Behav. 2019 Dec;99:106106. doi: 10.1016/j.addbeh.2019.106106. Epub 2019 Aug 20.


Evaluation of immunologic and intestinal effects in rats administered an E 171-containing diet, a food grade titanium dioxide (TiO2).

Blevins LK, Crawford RB, Bach A, Rizzo MD, Zhou J, Henriquez JE, Khan DMIO, Sermet S, Arnold LL, Pennington KL, Souza NP, Cohen SM, Kaminski NE.

Food Chem Toxicol. 2019 Nov;133:110793. doi: 10.1016/j.fct.2019.110793. Epub 2019 Aug 29.


Somewhere beyond the sea: Human cranial remains from the Lesser Sunda Islands (Alor Island, Indonesia) provide insights on Late Pleistocene peopling of Island Southeast Asia.

Samper Carro SC, Gilbert F, Bulbeck D, O'Connor S, Louys J, Spooner N, Questiaux D, Arnold L, Price GJ, Wood R, Mahirta.

J Hum Evol. 2019 Sep;134:102638. doi: 10.1016/j.jhevol.2019.07.002. Epub 2019 Aug 1.


Effects of Childhood and Adult Persistent Attention-Deficit/Hyperactivity Disorder on Risk of Motor Vehicle Crashes: Results From the Multimodal Treatment Study of ADHD.

Roy A, Garner AA, Epstein JN, Hoza B, Nichols JQ, Molina BSG, Swanson JM, Arnold LE, Hechtman L.

J Am Acad Child Adolesc Psychiatry. 2019 Aug 22. pii: S0890-8567(19)31458-3. doi: 10.1016/j.jaac.2019.08.007. [Epub ahead of print]


Trajectories of Growth Associated With Long-Term Stimulant Medication in the Multimodal Treatment Study of Attention-Deficit/Hyperactivity Disorder.

Greenhill LL, Swanson JM, Hechtman L, Waxmonsky J, Arnold LE, Molina BSG, Hinshaw SP, Jensen PS, Abikoff HB, Wigal T, Stehli A, Howard A, Hermanussen M, Hanć T; MTA Cooperative Group.

J Am Acad Child Adolesc Psychiatry. 2019 Aug 14. pii: S0890-8567(19)31443-1. doi: 10.1016/j.jaac.2019.06.019. [Epub ahead of print]


Role of tri-ponderal mass index in cardio-metabolic risk assessment in children and adolescents: compared with body mass index.

Wang X, Dong B, Ma J, Song Y, Zou Z, Arnold L.

Int J Obes (Lond). 2019 Jul 22. doi: 10.1038/s41366-019-0416-y. [Epub ahead of print]


The parmodulin NRD-21 is an allosteric inhibitor of PAR1 Gq signaling with improved anti-inflammatory activity and stability.

Gandhi DM, Rosas R Jr, Greve E, Kentala K, D-R Diby N, Snyder VA, Stephans A, Yeung THW, Subramaniam S, DiMilo E, Kurtenbach KE, Arnold LA, Weiler H, Dockendorff C.

Bioorg Med Chem. 2019 Sep 1;27(17):3788-3796. doi: 10.1016/j.bmc.2019.06.043. Epub 2019 Jun 29.


Smoking Cessation and Pregnancy: Timing of Cessation Reduces or Eliminates the Effect on Low Birth Weight.

Xaverius PK, O'Reilly Z, Li A, Flick LH, Arnold LD.

Matern Child Health J. 2019 Oct;23(10):1434-1441. doi: 10.1007/s10995-019-02751-2.


Efficacy and safety of mirogabalin for the treatment of fibromyalgia: results from three 13-week randomized, double-blind, placebo- and active-controlled, parallel-group studies and a 52-week open-label extension study.

Arnold LM, Whitaker S, Hsu C, Jacobs D, Merante D.

Curr Med Res Opin. 2019 Oct;35(10):1825-1835. doi: 10.1080/03007995.2019.1629757. Epub 2019 Jul 9.


Depression and ADHD-Related Risk for Substance Use in Adolescence and Early Adulthood: Concurrent and Prospective Associations in the MTA.

Howard AL, Kennedy TM, Macdonald EP, Mitchell JT, Sibley MH, Roy A, Arnold LE, Epstein JN, Hinshaw SP, Hoza B, Stehli A, Swanson JM, Molina BSG.

J Abnorm Child Psychol. 2019 Dec;47(12):1903-1916. doi: 10.1007/s10802-019-00573-y.


Stop the Bleed: Is Mass Education the Best Approach?

Motameni AT, Pike AI, Denzik KR, Arnold LF, Muradov JM, McKinley WI, Benns MV, Harbrecht BG.

Am Surg. 2019 Jun 1;85(6):601-605.


The SOFIA Study: Negative Multi-center Study of Low Dose Fluoxetine on Repetitive Behaviors in Children and Adolescents with Autistic Disorder.

Herscu P, Handen BL, Arnold LE, Snape MF, Bregman JD, Ginsberg L, Hendren R, Kolevzon A, Melmed R, Mintz M, Minshew N, Sikich L, Attalla A, King B, Owley T, Childress A, Chugani H, Frazier J, Cartwright C, Murphy T; Autism Speaks Autism Clinical Trials Network.

J Autism Dev Disord. 2019 Jul 2. doi: 10.1007/s10803-019-04120-y. [Epub ahead of print]


Patients' self-reported barriers to colon cancer screening in federally qualified health center settings.

Muthukrishnan M, Arnold LD, James AS.

Prev Med Rep. 2019 May 15;15:100896. doi: 10.1016/j.pmedr.2019.100896. eCollection 2019 Sep.


Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive Profiles.

Prevot TD, Li G, Vidojevic A, Misquitta KA, Fee C, Santrac A, Knutson DE, Stephen MR, Kodali R, Zahn NM, Arnold LA, Scholze P, Fisher JL, Marković BD, Banasr M, Cook JM, Savic M, Sibille E.

Mol Neuropsychiatry. 2019 Apr;5(2):84-97. doi: 10.1159/000496086. Epub 2019 Jan 23.


New bracketing luminescence ages constrain the Sima de los Huesos hominin fossils (Atapuerca, Spain) to MIS 12.

Demuro M, Arnold LJ, Aranburu A, Sala N, Arsuaga JL.

J Hum Evol. 2019 Jun;131:76-95. doi: 10.1016/j.jhevol.2018.12.003. Epub 2019 Apr 10.


Efficacy and safety of duloxetine versus placebo in adolescents with juvenile fibromyalgia: results from a randomized controlled trial.

Upadhyaya HP, Arnold LM, Alaka K, Qiao M, Williams D, Mehta R.

Pediatr Rheumatol Online J. 2019 May 28;17(1):27. doi: 10.1186/s12969-019-0325-6.


Tension Gastrothorax Causing Hemodynamic Instability in a Traumatic Diaphragm Rupture.

Royalty AK, Nash NA, Motameni AT, Arnold LF.

Am Surg. 2019 May 1;85(5):e260-e261. No abstract available.


The International Academy of Cytology Yokohama System for Reporting Breast Fine-Needle Aspiration Biopsy Cytopathology.

Field AS, Raymond WA, Rickard M, Arnold L, Brachtel EF, Chaiwun B, Chen L, Di Bonito L, Kurtycz DFI, Lee AHS, Lim E, Ljung BM, Michelow P, Osamura RY, Pinamonti M, Sauer T, Segara D, Tse G, Vielh P, Chong PY, Schmitt F.

Acta Cytol. 2019;63(4):257-273. doi: 10.1159/000499509. Epub 2019 May 21. Review.


Isolation and molecular characterization of spermatogonia from male Sprague-Dawley rats exposed in utero and postnatally to dibutyl phthalate or acrylamide.

Souza NP, Arnold LL, Pennington KL, Nascimento E Pontes MG, Miot HA, de Camargo JLV, Cohen SM.

Toxicol Mech Methods. 2019 Sep;29(7):488-498. doi: 10.1080/15376516.2019.1611981. Epub 2019 Jun 18.


Experimental cryptorchidism enhances testicular susceptibility to dibutyl phthalate or acrylamide in Sprague-Dawley rats.

de Souza NP, Cardoso AF, Gomide L, Lima T, Miot HA, Martino-Andrade AJ, Arnold LL, Pennington KL, Cohen SM, de Camargo J, Nascimento E Pontes MG.

Hum Exp Toxicol. 2019 Aug;38(8):899-913. doi: 10.1177/0960327119845040. Epub 2019 Apr 17.


Gastrointestinal and liver diseases and atrial fibrillation: a review of the literature.

Long MT, Ko D, Arnold LM, Trinquart L, Sherer JA, Keppel SS, Benjamin EJ, Helm RH.

Therap Adv Gastroenterol. 2019 Apr 2;12:1756284819832237. doi: 10.1177/1756284819832237. eCollection 2019. Review.


Spatial clusters of chronic preventable hospitalizations (ambulatory care sensitive conditions) and access to primary care.

Mazumdar S, Chong S, Arnold L, Jalaludin B.

J Public Health (Oxf). 2019 Apr 12. pii: fdz040. doi: 10.1093/pubmed/fdz040. [Epub ahead of print]


A Qualitative Analysis of Contextual Factors Relevant to Suspected Late-Onset ADHD.

Mitchell JT, Sibley MH, Hinshaw SP, Kennedy TM, Chronis-Tuscano A, Arnold LE, Swanson JM, Hechtman LT, Molina BSG, Caye A, Tamm L, Owens EB, Roy A, Weisner TS, Murray DW, Jensen PS.

J Atten Disord. 2019 Apr 1:1087054719837743. doi: 10.1177/1087054719837743. [Epub ahead of print]


Racial disparities in U.S. maternal influenza vaccine uptake: Results from analysis of Pregnancy Risk Assessment Monitoring System (PRAMS) data, 2012-2015.

Arnold LD, Luong L, Rebmann T, Chang JJ.

Vaccine. 2019 Apr 24;37(18):2520-2526. doi: 10.1016/j.vaccine.2019.02.014. Epub 2019 Mar 28.


Clinical and morphological predictors of outcome in older aplastic anemia patients treated with eltrombopag.

Fattizzo B, Kulasekararaj AG, Hill A, Benson-Quarm N, Griffin M, Munir T, Arnold L, Riley K, Ireland R, De Lavallade H, Potter V, Consonni D, Hillmen P, Mufti GJ, Barcellini W, Marsh JCW.

Haematologica. 2019 Nov;104(11):e494-e496. doi: 10.3324/haematol.2019.216374. Epub 2019 Mar 19. No abstract available.


Response to Wolfe. Letter to the Editor, "Fibromyalgia Criteria".

Arnold LM, Bennett RM, Crofford LJ, Dean LE, Clauw DJ, Goldenberg DL, Fitzcharles MA, Paiva ES, Staud R, Sarzi-Puttini P, Buskila D, Macfarlane GJ.

J Pain. 2019 Jun;20(6):741-742. doi: 10.1016/j.jpain.2019.02.003. Epub 2019 Feb 26. No abstract available.


MIDD0301 - A first-in-class anti-inflammatory asthma drug targets GABAA receptors without causing systemic immune suppression.

Zahn NM, Huber AT, Mikulsky BN, Stepanski ME, Kehoe AS, Li G, Schussman M, Rashid Roni MS, Kodali R, Cook JM, Stafford DC, Steeber DA, Arnold LA.

Basic Clin Pharmacol Toxicol. 2019 Jul;125(1):75-84. doi: 10.1111/bcpt.13206. Epub 2019 Feb 21.


Design and Evaluation of Heterobivalent PAR1-PAR2 Ligands as Antagonists of Calcium Mobilization.

Majewski MW, Gandhi DM, Rosas R Jr, Kodali R, Arnold LA, Dockendorff C.

ACS Med Chem Lett. 2018 Dec 3;10(1):121-126. doi: 10.1021/acsmedchemlett.8b00538. eCollection 2019 Jan 10.


Alternative binding sites at the vitamin D receptor and their ligands.

Mutchie TR, Yu OB, Di Milo ES, Arnold LA.

Mol Cell Endocrinol. 2019 Apr 5;485:1-8. doi: 10.1016/j.mce.2019.01.011. Epub 2019 Jan 14. Review.


Health Professional Training and Capacity Strengthening Through International Academic Partnerships: The First Five Years of the Human Resources for Health Program in Rwanda.

Cancedda C, Cotton P, Shema J, Rulisa S, Riviello R, Adams LV, Farmer PE, Kagwiza JN, Kyamanywa P, Mukamana D, Mumena C, Tumusiime DK, Mukashyaka L, Ndenga E, Twagirumugabe T, Mukara KB, Dusabejambo V, Walker TD, Nkusi E, Bazzett-Matabele L, Butera A, Rugwizangoga B, Kabayiza JC, Kanyandekwe S, Kalisa L, Ntirenganya F, Dixson J, Rogo T, McCall N, Corden M, Wong R, Mukeshimana M, Gatarayiha A, Ntagungira EK, Yaman A, Musabeyezu J, Sliney A, Nuthulaganti T, Kernan M, Okwi P, Rhatigan J, Barrow J, Wilson K, Levine AC, Reece R, Koster M, Moresky RT, O'Flaherty JE, Palumbo PE, Ginwalla R, Binanay CA, Thielman N, Relf M, Wright R, Hill M, Chyun D, Klar RT, McCreary LL, Hughes TL, Moen M, Meeks V, Barrows B, Durieux ME, McClain CD, Bunts A, Calland FJ, Hedt-Gauthier B, Milner D, Raviola G, Smith SE, Tuteja M, Magriples U, Rastegar A, Arnold L, Magaziner I, Binagwaho A.

Int J Health Policy Manag. 2018 Nov 1;7(11):1024-1039. doi: 10.15171/ijhpm.2018.61.


Attendance and Engagement in Parent Training Predict Child Behavioral Outcomes in Children Pharmacologically Treated for Attention-Deficit/Hyperactivity Disorder and Severe Aggression.

Joseph HM, Farmer C, Kipp H, Kolko D, Aman M, McGinley J, Arnold LE, Gadow KD, Findling RL, Molina BSG.

J Child Adolesc Psychopharmacol. 2019 Mar;29(2):90-99. doi: 10.1089/cap.2018.0119. Epub 2018 Dec 28.


Histopathology re-examination of the NTP toxicity/carcinogenicity studies of tert-butyl alcohol to identify renal tumor and toxicity modes of action.

Hard GC, Cohen SM, Ma J, Yu F, Arnold LL, Banton MI.

Regul Toxicol Pharmacol. 2019 Mar;102:65-73. doi: 10.1016/j.yrtph.2018.12.011. Epub 2018 Dec 24.


Palliative care initiation in pediatric oncology patients: A systematic review.

Cheng BT, Rost M, De Clercq E, Arnold L, Elger BS, Wangmo T.

Cancer Med. 2019 Jan;8(1):3-12. doi: 10.1002/cam4.1907. Epub 2018 Dec 7. Review.


A novel GABAA receptor ligand MIDD0301 with limited blood-brain barrier penetration relaxes airway smooth muscle ex vivo and in vivo.

Yocum GT, Perez-Zoghbi JF, Danielsson J, Kuforiji AS, Zhang Y, Li G, Rashid Roni MS, Kodali R, Stafford DC, Arnold LA, Cook JM, Emala CW Sr.

Am J Physiol Lung Cell Mol Physiol. 2019 Feb 1;316(2):L385-L390. doi: 10.1152/ajplung.00356.2018. Epub 2018 Nov 29.


Bullous Diabeticorum.

Arnold L, Vennard KC, Gilbert MP.

J Am Osteopath Assoc. 2018 Dec 1;118(12):832. doi: 10.7556/jaoa.2018.178. No abstract available.


Obtaining contextually relevant geographic data using Facebook recruitment in public health studies.

Nelson EJ, Loux T, Arnold LD, Siddiqui ST, Schootman M.

Health Place. 2019 Jan;55:37-42. doi: 10.1016/j.healthplace.2018.11.002. Epub 2018 Nov 19.


AMPK Activation Regulates LTBP4-Dependent TGF-β1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy.

Juban G, Saclier M, Yacoub-Youssef H, Kernou A, Arnold L, Boisson C, Ben Larbi S, Magnan M, Cuvellier S, Théret M, Petrof BJ, Desguerre I, Gondin J, Mounier R, Chazaud B.

Cell Rep. 2018 Nov 20;25(8):2163-2176.e6. doi: 10.1016/j.celrep.2018.10.077.

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