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Items: 1 to 50 of 264

1.

Conserved temporal ordering of promoter activation implicates common mechanisms governing the immediate early response across cell types and stimuli.

Vacca A, Itoh M, Kawaji H, Arner E, Lassmann T, Daub CO, Carninci P, Forrest ARR, Hayashizaki Y; FANTOM Consortium, Aitken S, Semple CA.

Open Biol. 2018 Aug;8(8). pii: 180011. doi: 10.1098/rsob.180011.

2.

Selenium research in biochemistry and biophysics - 200 year anniversary issue.

Arnér ESJ, Brigelius-Flohé R.

Biochim Biophys Acta. 2018 Jul 24. pii: S0304-4165(18)30220-4. doi: 10.1016/j.bbagen.2018.07.026. [Epub ahead of print] No abstract available.

PMID:
30053537
3.

Loss of Tbk1 kinase activity protects mice from diet-induced metabolic dysfunction.

Cruz VH, Arner EN, Wynne KW, Scherer PE, Brekken RA.

Mol Metab. 2018 Jun 11. pii: S2212-8778(18)30420-4. doi: 10.1016/j.molmet.2018.06.007. [Epub ahead of print]

4.

Efficient selenocysteine-dependent reduction of toxoflavin by mammalian thioredoxin reductase.

Gencheva R, Cheng Q, Arnér ESJ.

Biochim Biophys Acta. 2018 May 25. pii: S0304-4165(18)30146-6. doi: 10.1016/j.bbagen.2018.05.014. [Epub ahead of print]

PMID:
29807072
5.

Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry.

Silvestri I, Lyu H, Fata F, Boumis G, Miele AE, Ardini M, Ippoliti R, Bellelli A, Jadhav A, Lea WA, Simeonov A, Cheng Q, Arnér ESJ, Thatcher GRJ, Petukhov PA, Williams DL, Angelucci F.

ACS Chem Biol. 2018 Jun 11. doi: 10.1021/acschembio.8b00349. [Epub ahead of print]

PMID:
29800515
6.

Transcriptional landscape of Mycobacterium tuberculosis infection in macrophages.

Roy S, Schmeier S, Kaczkowski B, Arner E, Alam T, Ozturk M, Tamgue O, Parihar SP, Kawaji H, Itoh M, Lassmann T, Carninci P, Hayashizaki Y, Forrest ARR, Guler R, Bajic VB, Brombacher F, Suzuki H.

Sci Rep. 2018 Apr 30;8(1):6758. doi: 10.1038/s41598-018-24509-6.

7.

NADPH-dependent and -independent disulfide reductase systems.

Miller CG, Holmgren A, Arnér ESJ, Schmidt EE.

Free Radic Biol Med. 2018 Mar 30. pii: S0891-5849(18)30162-X. doi: 10.1016/j.freeradbiomed.2018.03.051. [Epub ahead of print] Review.

PMID:
29609022
8.

Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy.

Stafford WC, Peng X, Olofsson MH, Zhang X, Luci DK, Lu L, Cheng Q, Trésaugues L, Dexheimer TS, Coussens NP, Augsten M, Ahlzén HM, Orwar O, Östman A, Stone-Elander S, Maloney DJ, Jadhav A, Simeonov A, Linder S, Arnér ESJ.

Sci Transl Med. 2018 Feb 14;10(428). pii: eaaf7444. doi: 10.1126/scitranslmed.aaf7444.

PMID:
29444979
9.

Correction to: Relatively frequent switching of transcription start sites during cerebellar development.

Zhang P, Dimont E, Ha T, Swanson DJ, Itoh M, Kawaji H, Lassmann T, Daub CO, Arner E; FANTOM Consortium, Carninci P, Hayashizaki Y, Forrest ARR, Hide W, Goldowitz D.

BMC Genomics. 2018 Jan 11;19(1):39. doi: 10.1186/s12864-017-4291-4.

10.

Discovery of Transcription Factors Novel to Mouse Cerebellar Granule Cell Development Through Laser-Capture Microdissection.

Zhang PGY, Yeung J, Gupta I, Ramirez M, Ha T, Swanson DJ, Nagao-Sato S, Itoh M, Kawaji H, Lassmann T, Daub CO, Arner E, de Hoon M; FANTOM consortium, Carninci P, Forrest ARR, Hayashizaki Y, Goldowitz D.

Cerebellum. 2018 Jun;17(3):308-325. doi: 10.1007/s12311-017-0912-3.

PMID:
29307116
11.

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis.

Ingold I, Berndt C, Schmitt S, Doll S, Poschmann G, Buday K, Roveri A, Peng X, Porto Freitas F, Seibt T, Mehr L, Aichler M, Walch A, Lamp D, Jastroch M, Miyamoto S, Wurst W, Ursini F, Arnér ESJ, Fradejas-Villar N, Schweizer U, Zischka H, Friedmann Angeli JP, Conrad M.

Cell. 2018 Jan 25;172(3):409-422.e21. doi: 10.1016/j.cell.2017.11.048. Epub 2017 Dec 28.

PMID:
29290465
12.

The A to Z of modulated cell patterning by mammalian thioredoxin reductases.

Dagnell M, Schmidt EE, Arnér ESJ.

Free Radic Biol Med. 2018 Feb 1;115:484-496. doi: 10.1016/j.freeradbiomed.2017.12.029. Epub 2017 Dec 24. Review.

PMID:
29278740
13.

Targeting the Selenoprotein Thioredoxin Reductase 1 for Anticancer Therapy.

Arnér ESJ.

Adv Cancer Res. 2017;136:139-151. doi: 10.1016/bs.acr.2017.07.005. Epub 2017 Aug 23. Review.

PMID:
29054416
14.

Genome-scale regression analysis reveals a linear relationship for promoters and enhancers after combinatorial drug treatment.

Rapakoulia T, Gao X, Huang Y, de Hoon M, Okada-Hatakeyama M, Suzuki H, Arner E.

Bioinformatics. 2017 Dec 1;33(23):3696-3700. doi: 10.1093/bioinformatics/btx503.

15.

Transcriptome Analysis Uncovers a Growth-Promoting Activity of Orosomucoid-1 on Hepatocytes.

Qin XY, Hara M, Arner E, Kawaguchi Y, Inoue I, Tatsukawa H, Furutani Y, Nagatsuma K, Matsuura T, Wei F, Kikuchi J, Sone H, Daub C, Kawaji H, Lassmann T, Itoh M, Suzuki H, Carninci P, Hayashizaki Y; FANTOM consortium, Kokudo N, Forrest ARR, Kojima S.

EBioMedicine. 2017 Oct;24:257-266. doi: 10.1016/j.ebiom.2017.09.008. Epub 2017 Sep 12.

16.

Selective Evaluation of Thioredoxin Reductase Enzymatic Activities.

Arnér ESJ.

Methods Mol Biol. 2018;1661:301-309. doi: 10.1007/978-1-4939-7258-6_21.

PMID:
28917053
17.

Overexpression of Recombinant Selenoproteins in E. coli.

Cheng Q, Arnér ESJ.

Methods Mol Biol. 2018;1661:231-240. doi: 10.1007/978-1-4939-7258-6_17.

PMID:
28917049
18.

Systematic analysis of transcription start sites in avian development.

Lizio M, Deviatiiarov R, Nagai H, Galan L, Arner E, Itoh M, Lassmann T, Kasukawa T, Hasegawa A, Ros MA, Hayashizaki Y, Carninci P, Forrest ARR, Kawaji H, Gusev O, Sheng G.

PLoS Biol. 2017 Sep 5;15(9):e2002887. doi: 10.1371/journal.pbio.2002887. eCollection 2017 Sep.

19.

FANTOM5 CAGE profiles of human and mouse samples.

Noguchi S, Arakawa T, Fukuda S, Furuno M, Hasegawa A, Hori F, Ishikawa-Kato S, Kaida K, Kaiho A, Kanamori-Katayama M, Kawashima T, Kojima M, Kubosaki A, Manabe RI, Murata M, Nagao-Sato S, Nakazato K, Ninomiya N, Nishiyori-Sueki H, Noma S, Saijyo E, Saka A, Sakai M, Simon C, Suzuki N, Tagami M, Watanabe S, Yoshida S, Arner P, Axton RA, Babina M, Baillie JK, Barnett TC, Beckhouse AG, Blumenthal A, Bodega B, Bonetti A, Briggs J, Brombacher F, Carlisle AJ, Clevers HC, Davis CA, Detmar M, Dohi T, Edge ASB, Edinger M, Ehrlund A, Ekwall K, Endoh M, Enomoto H, Eslami A, Fagiolini M, Fairbairn L, Farach-Carson MC, Faulkner GJ, Ferrai C, Fisher ME, Forrester LM, Fujita R, Furusawa JI, Geijtenbeek TB, Gingeras T, Goldowitz D, Guhl S, Guler R, Gustincich S, Ha TJ, Hamaguchi M, Hara M, Hasegawa Y, Herlyn M, Heutink P, Hitchens KJ, Hume DA, Ikawa T, Ishizu Y, Kai C, Kawamoto H, Kawamura YI, Kempfle JS, Kenna TJ, Kere J, Khachigian LM, Kitamura T, Klein S, Klinken SP, Knox AJ, Kojima S, Koseki H, Koyasu S, Lee W, Lennartsson A, Mackay-Sim A, Mejhert N, Mizuno Y, Morikawa H, Morimoto M, Moro K, Morris KJ, Motohashi H, Mummery CL, Nakachi Y, Nakahara F, Nakamura T, Nakamura Y, Nozaki T, Ogishima S, Ohkura N, Ohno H, Ohshima M, Okada-Hatakeyama M, Okazaki Y, Orlando V, Ovchinnikov DA, Passier R, Patrikakis M, Pombo A, Pradhan-Bhatt S, Qin XY, Rehli M, Rizzu P, Roy S, Sajantila A, Sakaguchi S, Sato H, Satoh H, Savvi S, Saxena A, Schmidl C, Schneider C, Schulze-Tanzil GG, Schwegmann A, Sheng G, Shin JW, Sugiyama D, Sugiyama T, Summers KM, Takahashi N, Takai J, Tanaka H, Tatsukawa H, Tomoiu A, Toyoda H, van de Wetering M, van den Berg LM, Verardo R, Vijayan D, Wells CA, Winteringham LN, Wolvetang E, Yamaguchi Y, Yamamoto M, Yanagi-Mizuochi C, Yoneda M, Yonekura Y, Zhang PG, Zucchelli S, Abugessaisa I, Arner E, Harshbarger J, Kondo A, Lassmann T, Lizio M, Sahin S, Sengstag T, Severin J, Shimoji H, Suzuki M, Suzuki H, Kawai J, Kondo N, Itoh M, Daub CO, Kasukawa T, Kawaji H, Carninci P, Forrest ARR, Hayashizaki Y.

Sci Data. 2017 Aug 29;4:170112. doi: 10.1038/sdata.2017.112.

20.

An integrated expression atlas of miRNAs and their promoters in human and mouse.

de Rie D, Abugessaisa I, Alam T, Arner E, Arner P, Ashoor H, Åström G, Babina M, Bertin N, Burroughs AM, Carlisle AJ, Daub CO, Detmar M, Deviatiiarov R, Fort A, Gebhard C, Goldowitz D, Guhl S, Ha TJ, Harshbarger J, Hasegawa A, Hashimoto K, Herlyn M, Heutink P, Hitchens KJ, Hon CC, Huang E, Ishizu Y, Kai C, Kasukawa T, Klinken P, Lassmann T, Lecellier CH, Lee W, Lizio M, Makeev V, Mathelier A, Medvedeva YA, Mejhert N, Mungall CJ, Noma S, Ohshima M, Okada-Hatakeyama M, Persson H, Rizzu P, Roudnicky F, Sætrom P, Sato H, Severin J, Shin JW, Swoboda RK, Tarui H, Toyoda H, Vitting-Seerup K, Winteringham L, Yamaguchi Y, Yasuzawa K, Yoneda M, Yumoto N, Zabierowski S, Zhang PG, Wells CA, Summers KM, Kawaji H, Sandelin A, Rehli M; FANTOM Consortium, Hayashizaki Y, Carninci P, Forrest ARR, de Hoon MJL.

Nat Biotechnol. 2017 Sep;35(9):872-878. doi: 10.1038/nbt.3947. Epub 2017 Aug 21.

21.

Thioredoxin reductase 1 and NADPH directly protect protein tyrosine phosphatase 1B from inactivation during H2O2 exposure.

Dagnell M, Pace PE, Cheng Q, Frijhoff J, Östman A, Arnér ESJ, Hampton MB, Winterbourn CC.

J Biol Chem. 2017 Sep 1;292(35):14371-14380. doi: 10.1074/jbc.M117.793745. Epub 2017 Jul 6.

PMID:
28684416
22.

Hepatocyte Hyperproliferation upon Liver-Specific Co-disruption of Thioredoxin-1, Thioredoxin Reductase-1, and Glutathione Reductase.

Prigge JR, Coppo L, Martin SS, Ogata F, Miller CG, Bruschwein MD, Orlicky DJ, Shearn CT, Kundert JA, Lytchier J, Herr AE, Mattsson Å, Taylor MP, Gustafsson TN, Arnér ESJ, Holmgren A, Schmidt EE.

Cell Rep. 2017 Jun 27;19(13):2771-2781. doi: 10.1016/j.celrep.2017.06.019.

23.

Abdominal subcutaneous adipose tissue cellularity in men and women.

Andersson DP, Arner E, Hogling DE, Rydén M, Arner P.

Int J Obes (Lond). 2017 Oct;41(10):1564-1569. doi: 10.1038/ijo.2017.148. Epub 2017 Jun 20.

PMID:
28630459
24.

APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase.

Peng X, Zhang MQ, Conserva F, Hosny G, Selivanova G, Bykov VJ, Arnér ES, Wiman KG.

Cell Death Dis. 2017 Apr 13;8(4):e2751. doi: 10.1038/cddis.2016.137. No abstract available.

25.

Time- and cell-resolved dynamics of redox-sensitive Nrf2, HIF and NF-κB activities in 3D spheroids enriched for cancer stem cells.

Kipp AP, Deubel S, Arnér ESJ, Johansson K.

Redox Biol. 2017 Aug;12:403-409. doi: 10.1016/j.redox.2017.03.013. Epub 2017 Mar 10.

26.

Rutin protects against H2O2-triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress.

Sthijns MMJPE, Schiffers PM, Janssen GM, Lemmens KJA, Ides B, Vangrieken P, Bouwman FG, Mariman EC, Pader I, Arnér ESJ, Johansson K, Bast A, Haenen GRMM.

Biochim Biophys Acta. 2017 May;1861(5 Pt A):1177-1189. doi: 10.1016/j.bbagen.2017.03.004. Epub 2017 Mar 7.

PMID:
28286015
27.

Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease.

Baillie JK, Arner E, Daub C, De Hoon M, Itoh M, Kawaji H, Lassmann T, Carninci P, Forrest AR, Hayashizaki Y; FANTOM Consortium, Faulkner GJ, Wells CA, Rehli M, Pavli P, Summers KM, Hume DA.

PLoS Genet. 2017 Mar 6;13(3):e1006641. doi: 10.1371/journal.pgen.1006641. eCollection 2017 Mar.

28.

An atlas of human long non-coding RNAs with accurate 5' ends.

Hon CC, Ramilowski JA, Harshbarger J, Bertin N, Rackham OJ, Gough J, Denisenko E, Schmeier S, Poulsen TM, Severin J, Lizio M, Kawaji H, Kasukawa T, Itoh M, Burroughs AM, Noma S, Djebali S, Alam T, Medvedeva YA, Testa AC, Lipovich L, Yip CW, Abugessaisa I, Mendez M, Hasegawa A, Tang D, Lassmann T, Heutink P, Babina M, Wells CA, Kojima S, Nakamura Y, Suzuki H, Daub CO, de Hoon MJ, Arner E, Hayashizaki Y, Carninci P, Forrest AR.

Nature. 2017 Mar 9;543(7644):199-204. doi: 10.1038/nature21374. Epub 2017 Mar 1.

PMID:
28241135
29.

Homozygous mutation in TXNRD1 is associated with genetic generalized epilepsy.

Kudin AP, Baron G, Zsurka G, Hampel KG, Elger CE, Grote A, Weber Y, Lerche H, Thiele H, Nürnberg P, Schulz H, Ruppert AK, Sander T, Cheng Q, Arnér ES, Schomburg L, Seeher S, Fradejas-Villar N, Schweizer U, Kunz WS.

Free Radic Biol Med. 2017 May;106:270-277. doi: 10.1016/j.freeradbiomed.2017.02.040. Epub 2017 Feb 21.

PMID:
28232204
30.
31.

Cytosolic thioredoxin reductase 1 is required for correct disulfide formation in the ER.

Poet GJ, Oka OB, van Lith M, Cao Z, Robinson PJ, Pringle MA, Arnér ES, Bulleid NJ.

EMBO J. 2017 Mar 1;36(5):693-702. doi: 10.15252/embj.201695336. Epub 2017 Jan 16.

32.

Transcriptional Dynamics During Human Adipogenesis and Its Link to Adipose Morphology and Distribution.

Ehrlund A, Mejhert N, Björk C, Andersson R, Kulyté A, Åström G, Itoh M, Kawaji H, Lassmann T, Daub CO, Carninci P, Forrest AR, Hayashizaki Y, Sandelin A, Ingelsson E; FANTOM Consortium, Rydén M, Laurencikiene J, Arner P, Arner E.

Diabetes. 2017 Jan;66(1):218-230. doi: 10.2337/db16-0631. Epub 2016 Nov 1.

33.

Discriminative identification of transcriptional responses of promoters and enhancers after stimulus.

Kleftogiannis D, Kalnis P, Arner E, Bajic VB.

Nucleic Acids Res. 2017 Feb 28;45(4):e25. doi: 10.1093/nar/gkw1015.

34.

Indolin-2-one compounds targeting thioredoxin reductase as potential anticancer drug leads.

Kaminska KK, Bertrand HC, Tajima H, Stafford WC, Cheng Q, Chen W, Wells G, Arner ES, Chew EH.

Oncotarget. 2016 Jun 28;7(26):40233-40251. doi: 10.18632/oncotarget.9579.

35.

Serum thioredoxin reductase is highly increased in mice with hepatocellular carcinoma and its activity is restrained by several mechanisms.

Zhang L, Cheng Q, Zhang L, Wang Y, Merrill GF, Ilani T, Fass D, Arnér ESJ, Zhang J.

Free Radic Biol Med. 2016 Oct;99:426-435. doi: 10.1016/j.freeradbiomed.2016.08.028. Epub 2016 Aug 28.

PMID:
27581528
36.

Selenoprotein Gene Nomenclature.

Gladyshev VN, Arnér ES, Berry MJ, Brigelius-Flohé R, Bruford EA, Burk RF, Carlson BA, Castellano S, Chavatte L, Conrad M, Copeland PR, Diamond AM, Driscoll DM, Ferreiro A, Flohé L, Green FR, Guigó R, Handy DE, Hatfield DL, Hesketh J, Hoffmann PR, Holmgren A, Hondal RJ, Howard MT, Huang K, Kim HY, Kim IY, Köhrle J, Krol A, Kryukov GV, Lee BJ, Lee BC, Lei XG, Liu Q, Lescure A, Lobanov AV, Loscalzo J, Maiorino M, Mariotti M, Sandeep Prabhu K, Rayman MP, Rozovsky S, Salinas G, Schmidt EE, Schomburg L, Schweizer U, Simonović M, Sunde RA, Tsuji PA, Tweedie S, Ursini F, Whanger PD, Zhang Y.

J Biol Chem. 2016 Nov 11;291(46):24036-24040. Epub 2016 Sep 19.

37.

Entinostat up-regulates the CAMP gene encoding LL-37 via activation of STAT3 and HIF-1α transcription factors.

Miraglia E, Nylén F, Johansson K, Arnér E, Cebula M, Farmand S, Ottosson H, Strömberg R, Gudmundsson GH, Agerberth B, Bergman P.

Sci Rep. 2016 Sep 16;6:33274. doi: 10.1038/srep33274.

38.

Datasets of genes coexpressed with FBN1 in mouse adipose tissue and during human adipogenesis.

Davis MR, Arner E, Duffy CR, De Sousa PA, Dahlman I, Arner P, Summers KM.

Data Brief. 2016 Jul 5;8:851-7. doi: 10.1016/j.dib.2016.06.055. eCollection 2016 Sep.

39.

Functional Crosstalk between the PP2A and SUMO Pathways Revealed by Analysis of STUbL Suppressor, razor 1-1.

Nie M, Arner E, Prudden J, Schaffer L, Head S, Boddy MN.

PLoS Genet. 2016 Jul 11;12(7):e1006165. doi: 10.1371/journal.pgen.1006165. eCollection 2016 Jul.

40.

Preclinical PET imaging of EGFR levels: pairing a targeting with a non-targeting Sel-tagged Affibody-based tracer to estimate the specific uptake.

Cheng Q, Wållberg H, Grafström J, Lu L, Thorell JO, Hägg Olofsson M, Linder S, Johansson K, Tegnebratt T, Arnér ES, Stone-Elander S, Ahlzén HS, Ståhl S; Sel-tag imaging project.

EJNMMI Res. 2016 Dec;6(1):58. doi: 10.1186/s13550-016-0213-8. Epub 2016 Jul 7.

41.

Expression of FBN1 during adipogenesis: Relevance to the lipodystrophy phenotype in Marfan syndrome and related conditions.

Davis MR, Arner E, Duffy CR, De Sousa PA, Dahlman I, Arner P, Summers KM.

Mol Genet Metab. 2016 Sep;119(1-2):174-85. doi: 10.1016/j.ymgme.2016.06.009. Epub 2016 Jun 23.

42.

Inhibitory nitrosylation of mammalian thioredoxin reductase 1: Molecular characterization and evidence for its functional role in cellular nitroso-redox imbalance.

Engelman R, Ziv T, Arnér ESJ, Benhar M.

Free Radic Biol Med. 2016 Aug;97:375-385. doi: 10.1016/j.freeradbiomed.2016.06.032. Epub 2016 Jul 1.

PMID:
27377780
43.

Thioredoxin reductase 1 suppresses adipocyte differentiation and insulin responsiveness.

Peng X, Giménez-Cassina A, Petrus P, Conrad M, Rydén M, Arnér ES.

Sci Rep. 2016 Jun 27;6:28080. doi: 10.1038/srep28080.

44.

DeepCAGE transcriptomics identify HOXD10 as a transcription factor regulating lymphatic endothelial responses to VEGF-C.

Klein S, Dieterich LC, Mathelier A, Chong C, Sliwa-Primorac A, Hong YK, Shin JW, Lizio M, Itoh M, Kawaji H, Lassmann T, Daub CO, Arner E; FANTOM consortium, Carninci P, Hayashizaki Y, Forrest AR, Wasserman WW, Detmar M.

J Cell Sci. 2016 Jul 1;129(13):2573-85. doi: 10.1242/jcs.186767. Epub 2016 May 19.

45.

Chemical Reactivity Window Determines Prodrug Efficiency toward Glutathione Transferase Overexpressing Cancer Cells.

van Gisbergen MW, Cebula M, Zhang J, Ottosson-Wadlund A, Dubois L, Lambin P, Tew KD, Townsend DM, Haenen GR, Drittij-Reijnders MJ, Saneyoshi H, Araki M, Shishido Y, Ito Y, Arnér ES, Abe H, Morgenstern R, Johansson K.

Mol Pharm. 2016 Jun 6;13(6):2010-25. doi: 10.1021/acs.molpharmaceut.6b00140. Epub 2016 Apr 28.

46.

Functional annotation of the vlinc class of non-coding RNAs using systems biology approach.

St Laurent G, Vyatkin Y, Antonets D, Ri M, Qi Y, Saik O, Shtokalo D, de Hoon MJ, Kawaji H, Itoh M, Lassmann T, Arner E, Forrest AR; FANTOM consortium, Nicolas E, McCaffrey TA, Carninci P, Hayashizaki Y, Wahlestedt C, Kapranov P.

Nucleic Acids Res. 2016 Apr 20;44(7):3233-52. doi: 10.1093/nar/gkw162. Epub 2016 Mar 21.

47.

Details in the catalytic mechanism of mammalian thioredoxin reductase 1 revealed using point mutations and juglone-coupled enzyme activities.

Xu J, Cheng Q, Arnér ES.

Free Radic Biol Med. 2016 May;94:110-20. doi: 10.1016/j.freeradbiomed.2016.02.013. Epub 2016 Feb 17.

PMID:
26898501
48.

A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredoxin and glutathione systems.

Dóka É, Pader I, Bíró A, Johansson K, Cheng Q, Ballagó K, Prigge JR, Pastor-Flores D, Dick TP, Schmidt EE, Arnér ES, Nagy P.

Sci Adv. 2016 Jan 22;2(1):e1500968. doi: 10.1126/sciadv.1500968. eCollection 2016 Jan.

49.

Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications.

Lei XG, Zhu JH, Cheng WH, Bao Y, Ho YS, Reddi AR, Holmgren A, Arnér ES.

Physiol Rev. 2016 Jan;96(1):307-64. doi: 10.1152/physrev.00010.2014. Review.

50.

Remodeling of retrotransposon elements during epigenetic induction of adult visual cortical plasticity by HDAC inhibitors.

Lennartsson A, Arner E, Fagiolini M, Saxena A, Andersson R, Takahashi H, Noro Y, Sng J, Sandelin A, Hensch TK, Carninci P.

Epigenetics Chromatin. 2015 Dec 14;8:55. doi: 10.1186/s13072-015-0043-3. eCollection 2015.

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