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Items: 1 to 50 of 155

1.

Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy.

Pfitzer L, Moser C, Gegenfurtner F, Arner A, Foerster F, Atzberger C, Zisis T, Kubisch-Dohmen R, Busse J, Smith R, Timinszky G, Kalinina OV, Müller R, Wagner E, Vollmar AM, Zahler S.

Cell Death Dis. 2019 Apr 3;10(4):302. doi: 10.1038/s41419-019-1546-9.

2.

Aortic effects of thyroid hormone in male mice.

Gachkar S, Nock S, Geissler C, Oelkrug R, Johann K, Resch J, Rahman A, Arner A, Kirchner H, Mittag J.

J Mol Endocrinol. 2019 Apr 1;62(3):91-99. doi: 10.1530/JME-18-0217.

PMID:
30608905
3.

De novo mutations in FLNC leading to early-onset restrictive cardiomyopathy and congenital myopathy.

Kiselev A, Vaz R, Knyazeva A, Khudiakov A, Tarnovskaya S, Liu J, Sergushichev A, Kazakov S, Frishman D, Smolina N, Pervunina T, Jorholt J, Sjoberg G, Vershinina T, Rudenko D, Arner A, Sejersen T, Lindstrand A, Kostareva A.

Hum Mutat. 2018 Sep;39(9):1161-1172. doi: 10.1002/humu.23559. Epub 2018 Jun 17.

PMID:
29858533
4.

Rigor bonds cause reduced sarcomeric volume in skinned porcine skeletal muscle under PSE-like conditions.

Liu J, Schwartzkopf M, Arner A.

Meat Sci. 2018 May;139:91-96. doi: 10.1016/j.meatsci.2018.01.014. Epub 2018 Feb 3.

PMID:
29413682
5.

Vascular smooth muscle contraction in hypertension.

Touyz RM, Alves-Lopes R, Rios FJ, Camargo LL, Anagnostopoulou A, Arner A, Montezano AC.

Cardiovasc Res. 2018 Mar 15;114(4):529-539. doi: 10.1093/cvr/cvy023. Review.

6.

Signaling and metabolic properties of fast and slow smooth muscle types from mice.

Boberg L, Szekeres FLM, Arner A.

Pflugers Arch. 2018 Apr;470(4):681-691. doi: 10.1007/s00424-017-2096-6. Epub 2018 Jan 29.

7.

Increased Vulnerability of the Hippocampus in Transgenic Mice Overexpressing APP and Triple Repeat Tau.

Arner A, Rockenstein E, Mante M, Florio J, Masliah D, Salehi B, Adame A, Overk C, Masliah E, Rissman RA.

J Alzheimers Dis. 2018;61(3):1201-1219. doi: 10.3233/JAD-170388.

8.

In Vivo Function of the Chaperonin TRiC in α-Actin Folding during Sarcomere Assembly.

Berger J, Berger S, Li M, Jacoby AS, Arner A, Bavi N, Stewart AG, Currie PD.

Cell Rep. 2018 Jan 9;22(2):313-322. doi: 10.1016/j.celrep.2017.12.069.

9.

Long-term cardiovascular reprogramming by short-term perinatal exposure to nicotine's main metabolite cotinine.

Bastianini S, Lo Martire V, Silvani A, Zoccoli G, Berteotti C, Lagercrantz H, Arner A, Cohen G.

Acta Paediatr. 2018 Apr;107(4):638-646. doi: 10.1111/apa.14181. Epub 2018 Jan 4.

PMID:
29224235
10.

Ion currents of cardiomyocytes in different regions of the Göttingen minipig heart.

Arlock P, Mow T, Sjöberg T, Arner A, Steen S, Laursen M.

J Pharmacol Toxicol Methods. 2017 Jul;86:12-18. doi: 10.1016/j.vascn.2017.02.022. Epub 2017 Feb 22.

PMID:
28254506
11.

Blood pressure regulation by CD4+ lymphocytes expressing choline acetyltransferase.

Olofsson PS, Steinberg BE, Sobbi R, Cox MA, Ahmed MN, Oswald M, Szekeres F, Hanes WM, Introini A, Liu SF, Holodick NE, Rothstein TL, Lövdahl C, Chavan SS, Yang H, Pavlov VA, Broliden K, Andersson U, Diamond B, Miller EJ, Arner A, Gregersen PK, Backx PH, Mak TW, Tracey KJ.

Nat Biotechnol. 2016 Oct;34(10):1066-1071. doi: 10.1038/nbt.3663. Epub 2016 Sep 12.

12.

On the water-holding of myofibrils: Effect of sarcoplasmic protein denaturation.

Liu J, Arner A, Puolanne E, Ertbjerg P.

Meat Sci. 2016 Sep;119:32-40. doi: 10.1016/j.meatsci.2016.04.020. Epub 2016 Apr 19.

PMID:
27129081
13.

Role of Active Contraction and Tropomodulins in Regulating Actin Filament Length and Sarcomere Structure in Developing Zebrafish Skeletal Muscle.

Mazelet L, Parker MO, Li M, Arner A, Ashworth R.

Front Physiol. 2016 Mar 31;7:91. doi: 10.3389/fphys.2016.00091. eCollection 2016.

14.

Knockdown of fast skeletal myosin-binding protein C in zebrafish results in a severe skeletal myopathy.

Li M, Andersson-Lendahl M, Sejersen T, Arner A.

J Gen Physiol. 2016 Apr;147(4):309-22. doi: 10.1085/jgp.201511452.

15.

X-ray phase-contrast tomography for high-spatial-resolution zebrafish muscle imaging.

Vågberg W, Larsson DH, Li M, Arner A, Hertz HM.

Sci Rep. 2015 Nov 13;5:16625. doi: 10.1038/srep16625.

16.

Immobilization of Dystrophin and Laminin α2-Chain Deficient Zebrafish Larvae In Vivo Prevents the Development of Muscular Dystrophy.

Li M, Arner A.

PLoS One. 2015 Nov 4;10(11):e0139483. doi: 10.1371/journal.pone.0139483. eCollection 2015.

17.

Adaptation of active tone in the mouse descending thoracic aorta under acute changes in loading.

Murtada SI, Lewin S, Arner A, Humphrey JD.

Biomech Model Mechanobiol. 2016 Jun;15(3):579-92. doi: 10.1007/s10237-015-0711-z. Epub 2015 Jul 29.

18.

Protein kinase C activation of a blebbistatin sensitive contractile component in the wall of hypertrophying mouse urinary bladder.

Boberg L, Rahman A, Poljakovic M, Arner A.

Neurourol Urodyn. 2015 Feb;34(2):196-202. doi: 10.1002/nau.22531. Epub 2013 Nov 26.

PMID:
25794194
19.

Loss of Tropomodulin4 in the zebrafish mutant träge causes cytoplasmic rod formation and muscle weakness reminiscent of nemaline myopathy.

Berger J, Tarakci H, Berger S, Li M, Hall TE, Arner A, Currie PD.

Dis Model Mech. 2014 Dec;7(12):1407-15. doi: 10.1242/dmm.017376. Epub 2014 Oct 2.

20.

Muscle dysfunction and structural defects of dystrophin-null sapje mutant zebrafish larvae are rescued by ataluren treatment.

Li M, Andersson-Lendahl M, Sejersen T, Arner A.

FASEB J. 2014 Apr;28(4):1593-9. doi: 10.1096/fj.13-240044. Epub 2013 Dec 26.

PMID:
24371125
21.

The small GTPase Rac1 is required for smooth muscle contraction.

Rahman A, Davis B, Lövdahl C, Hanumaiah VT, Feil R, Brakebusch C, Arner A.

J Physiol. 2014 Mar 1;592(5):915-26. doi: 10.1113/jphysiol.2013.262998. Epub 2013 Dec 2.

22.

Inappropriate heat dissipation ignites brown fat thermogenesis in mice with a mutant thyroid hormone receptor α1.

Warner A, Rahman A, Solsjö P, Gottschling K, Davis B, Vennström B, Arner A, Mittag J.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16241-6. doi: 10.1073/pnas.1310300110. Epub 2013 Sep 17.

23.

The zebrafish amyloid precursor protein-b is required for motor neuron guidance and synapse formation.

Abramsson A, Kettunen P, Banote RK, Lott E, Li M, Arner A, Zetterberg H.

Dev Biol. 2013 Sep 15;381(2):377-88. doi: 10.1016/j.ydbio.2013.06.026. Epub 2013 Jul 9.

24.

Knockdown of desmin in zebrafish larvae affects interfilament spacing and mechanical properties of skeletal muscle.

Li M, Andersson-Lendahl M, Sejersen T, Arner A.

J Gen Physiol. 2013 Mar;141(3):335-45. doi: 10.1085/jgp.201210915.

25.

Thyroid hormone is required for hypothalamic neurons regulating cardiovascular functions.

Mittag J, Lyons DJ, Sällström J, Vujovic M, Dudazy-Gralla S, Warner A, Wallis K, Alkemade A, Nordström K, Monyer H, Broberger C, Arner A, Vennström B.

J Clin Invest. 2013 Jan;123(1):509-16. doi: 10.1172/JCI65252. Epub 2012 Dec 21.

26.

AMP-activated kinase relaxes agonist induced contractions in the mouse aorta via effects on PKC signaling and inhibits NO-induced relaxation.

Davis B, Rahman A, Arner A.

Eur J Pharmacol. 2012 Nov 15;695(1-3):88-95. doi: 10.1016/j.ejphar.2012.07.025. Epub 2012 Aug 19.

PMID:
22921370
27.

Busulphan-cyclophosphamide cause endothelial injury, remodeling of resistance arteries and enhanced expression of endothelial nitric oxide synthase.

Al-Hashmi S, Boels PJ, Zadjali F, Sadeghi B, Sällström J, Hultenby K, Hassan Z, Arner A, Hassan M.

PLoS One. 2012;7(1):e30897. doi: 10.1371/journal.pone.0030897. Epub 2012 Jan 27.

28.

Experiments and mechanochemical modeling of smooth muscle contraction: significance of filament overlap.

Murtada SC, Arner A, Holzapfel GA.

J Theor Biol. 2012 Mar 21;297:176-86. doi: 10.1016/j.jtbi.2011.11.012. Epub 2011 Nov 18.

PMID:
22108241
29.

Developmental toxicity of the environmental pollutant 4-nonylphenol in zebrafish.

Chandrasekar G, Arner A, Kitambi SS, Dahlman-Wright K, Lendahl MA.

Neurotoxicol Teratol. 2011 Nov-Dec;33(6):752-64. doi: 10.1016/j.ntt.2011.09.009. Epub 2011 Oct 5.

PMID:
22002180
30.

Role of Rho-kinase and protein kinase C during contraction of hypertrophic detrusor in mice with partial urinary bladder outlet obstruction.

Boberg L, Poljakovic M, Rahman A, Eccles R, Arner A.

BJU Int. 2012 Jan;109(1):132-40. doi: 10.1111/j.1464-410X.2011.10435.x. Epub 2011 Aug 29.

31.

Multiple phenotypes in adult mice following inactivation of the Coxsackievirus and Adenovirus Receptor (Car) gene.

Pazirandeh A, Sultana T, Mirza M, Rozell B, Hultenby K, Wallis K, Vennström B, Davis B, Arner A, Heuchel R, Löhr M, Philipson L, Sollerbrant K.

PLoS One. 2011;6(6):e20203. doi: 10.1371/journal.pone.0020203. Epub 2011 Jun 3.

32.

Intimal hyperplasia in balloon dilated coronary arteries is reduced by local delivery of the NO donor, SIN-1 via a cGMP-dependent pathway.

Harnek J, Zoucas E, de Sá VP, Ekblad E, Arner A, Stenram U.

BMC Cardiovasc Disord. 2011 Jun 11;11:30. doi: 10.1186/1471-2261-11-30.

33.

Recapitulation of developmental cardiogenesis governs the morphological and functional regeneration of adult newt hearts following injury.

Witman N, Murtuza B, Davis B, Arner A, Morrison JI.

Dev Biol. 2011 Jun 1;354(1):67-76. doi: 10.1016/j.ydbio.2011.03.021. Epub 2011 Mar 30.

34.

Inflammation-induced airway smooth muscle responsiveness is strain dependent in mice.

Säfholm J, Lövdahl C, Swedin L, Boels PJ, Dahlén SE, Arner A, Adner M.

Pulm Pharmacol Ther. 2011 Aug;24(4):361-6. doi: 10.1016/j.pupt.2011.01.001. Epub 2011 Jan 19. Review.

PMID:
21255673
35.

Endotoxin induces differentiated contractile responses in porcine pulmonary arteries and veins.

Persson BP, Boels PJ, Lövdahl C, Rossi P, Arner A, Oldner A.

J Vasc Res. 2011;48(3):206-18. doi: 10.1159/000319796. Epub 2010 Nov 23.

36.

Adaptations of the autonomous nervous system controlling heart rate are impaired by a mutant thyroid hormone receptor-alpha1.

Mittag J, Davis B, Vujovic M, Arner A, Vennström B.

Endocrinology. 2010 May;151(5):2388-95. doi: 10.1210/en.2009-1201. Epub 2010 Mar 12.

PMID:
20228172
37.

Adenosine A(1) receptors and vascular reactivity.

Wang Y, Yang JN, Arner A, Boels PJ, Fredholm BB.

Acta Physiol (Oxf). 2010 Jun;199(2):211-20. doi: 10.1111/j.1748-1716.2010.02093.x. Epub 2010 Feb 2.

PMID:
20132147
38.

Separate and overlapping metabolic functions of LXRalpha and LXRbeta in C57Bl/6 female mice.

Korach-André M, Parini P, Larsson L, Arner A, Steffensen KR, Gustafsson JA.

Am J Physiol Endocrinol Metab. 2010 Feb;298(2):E167-78. doi: 10.1152/ajpendo.00184.2009. Epub 2009 Aug 18.

39.

Receptor-induced phasic activity of newborn mouse bladders is inhibited by protein kinase C and involves T-type Ca2+ channels.

Ekman M, Andersson KE, Arner A.

BJU Int. 2009 Sep;104(5):690-7. doi: 10.1111/j.1464-410X.2009.08576.x. Epub 2009 Apr 17.

40.

Bosentan enhances viral load via endothelin-1 receptor type-A-mediated p38 mitogen-activated protein kinase activation while improving cardiac function during coxsackievirus-induced myocarditis.

Marchant D, Dou Y, Luo H, Garmaroudi FS, McDonough JE, Si X, Walker E, Luo Z, Arner A, Hegele RG, Laher I, McManus BM.

Circ Res. 2009 Mar 27;104(6):813-21. doi: 10.1161/CIRCRESAHA.108.191171. Epub 2009 Feb 12.

PMID:
19213955
41.

Signal transduction pathways of muscarinic receptor mediated activation in the newborn and adult mouse urinary bladder.

Ekman M, Andersson KE, Arner A.

BJU Int. 2009 Jan;103(1):90-7. doi: 10.1111/j.1464-410X.2008.07935.x. Epub 2008 Aug 22.

42.

Role of desmin in active force transmission and maintenance of structure during growth of urinary bladder.

Scott RS, Li Z, Paulin D, Uvelius B, Small JV, Arner A.

Am J Physiol Cell Physiol. 2008 Aug;295(2):C324-31. doi: 10.1152/ajpcell.90622.2007. Epub 2008 Jun 18.

43.

Structure and function of skeletal muscle in zebrafish early larvae.

Dou Y, Andersson-Lendahl M, Arner A.

J Gen Physiol. 2008 May;131(5):445-53. doi: 10.1085/jgp.200809982.

44.

An in vitro model for studying neuromuscular transmission in the mouse pharynx.

Ekberg O, Ekman M, Eriksson LI, Malm R, Sundman E, Arner A.

Dysphagia. 2009 Mar;24(1):32-9. doi: 10.1007/s00455-008-9168-x. Epub 2008 Apr 25.

PMID:
18437460
45.

Endotoxemic pulmonary hypertension is largely mediated by endothelin-induced venous constriction.

Rossi P, Persson B, Boels PJ, Arner A, Weitzberg E, Oldner A.

Intensive Care Med. 2008 May;34(5):873-80. doi: 10.1007/s00134-007-0980-9. Epub 2008 Jan 24.

PMID:
18214440
46.

Hypermetabolism in mice caused by the central action of an unliganded thyroid hormone receptor alpha1.

Sjögren M, Alkemade A, Mittag J, Nordström K, Katz A, Rozell B, Westerblad H, Arner A, Vennström B.

EMBO J. 2007 Oct 31;26(21):4535-45. Epub 2007 Oct 11.

47.

Intracellular calcium in hypertrophic smooth muscle from rat urinary bladder.

Arner A, Sjuve Scott R, Haase H, Morano I, Uvelius B.

Scand J Urol Nephrol. 2007;41(4):270-7.

PMID:
17763216
48.

Blebbistatin specifically inhibits actin-myosin interaction in mouse cardiac muscle.

Dou Y, Arlock P, Arner A.

Am J Physiol Cell Physiol. 2007 Sep;293(3):C1148-53. Epub 2007 Jul 5.

49.

Increased Rho activation and PKC-mediated smooth muscle contractility in the absence of caveolin-1.

Shakirova Y, Bonnevier J, Albinsson S, Adner M, Rippe B, Broman J, Arner A, Swärd K.

Am J Physiol Cell Physiol. 2006 Dec;291(6):C1326-35.

50.

Lung dysfunction causes systemic hypoxia in estrogen receptor beta knockout (ERbeta-/-) mice.

Morani A, Barros RP, Imamov O, Hultenby K, Arner A, Warner M, Gustafsson JA.

Proc Natl Acad Sci U S A. 2006 May 2;103(18):7165-9. Epub 2006 Apr 24.

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