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Treatment with diphenyl-pyrazole compound anle138b/c reveals that α-synuclein protects melanoma cells from autophagic cell death.

Turriani E, Lázaro DF, Ryazanov S, Leonov A, Giese A, Schön M, Schön MP, Griesinger C, Outeiro TF, Arndt-Jovin DJ, Becker D.

Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):E4971-E4977. doi: 10.1073/pnas.1700200114. Epub 2017 Jun 5.


Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells.

Oliveira LM, Falomir-Lockhart LJ, Botelho MG, Lin KH, Wales P, Koch JC, Gerhardt E, Taschenberger H, Outeiro TF, Lingor P, Schüle B, Arndt-Jovin DJ, Jovin TM.

Cell Death Dis. 2015 Nov 26;6:e1994. doi: 10.1038/cddis.2015.318.


Enhanced dimerization drives ligand-independent activity of mutant epidermal growth factor receptor in lung cancer.

Valley CC, Arndt-Jovin DJ, Karedla N, Steinkamp MP, Chizhik AI, Hlavacek WS, Wilson BS, Lidke KA, Lidke DS.

Mol Biol Cell. 2015 Nov 5;26(22):4087-99. doi: 10.1091/mbc.E15-05-0269. Epub 2015 Sep 2.


Conformational variability of recombination R-triplex formed by the mammalian telomeric sequence.

Shchyolkina AK, Kaluzhny DN, Borisova OF, Arndt-Jovin DJ, Jovin TM, Zhurkin VB.

J Biomol Struct Dyn. 2016 Jun;34(6):1298-306. doi: 10.1080/07391102.2015.1077344. Epub 2015 Oct 15.


Fluorogen activating protein-affibody probes: modular, no-wash measurement of epidermal growth factor receptors.

Wang Y, Telmer CA, Schmidt BF, Franke JD, Ort S, Arndt-Jovin DJ, Bruchez MP.

Bioconjug Chem. 2015 Jan 21;26(1):137-44. doi: 10.1021/bc500525b. Epub 2014 Dec 19.


Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication.

Flierl A, Oliveira LM, Falomir-Lockhart LJ, Mak SK, Hesley J, Soldner F, Arndt-Jovin DJ, Jaenisch R, Langston JW, Jovin TM, Schüle B.

PLoS One. 2014 Nov 12;9(11):e112413. doi: 10.1371/journal.pone.0112413. eCollection 2014.


Structure-function relationships of ErbB RTKs in the plasma membrane of living cells.

Arndt-Jovin DJ, Botelho MG, Jovin TM.

Cold Spring Harb Perspect Biol. 2014 Apr 1;6(4):a008961. doi: 10.1101/cshperspect.a008961. Review.


Magnetic nanoparticles as mediators of ligand-free activation of EGFR signaling.

Bharde AA, Palankar R, Fritsch C, Klaver A, Kanger JS, Jovin TM, Arndt-Jovin DJ.

PLoS One. 2013 Jul 23;8(7):e68879. doi: 10.1371/journal.pone.0068879. Print 2013.


Dynamic conformational transitions of the EGF receptor in living mammalian cells determined by FRET and fluorescence lifetime imaging microscopy.

Ziomkiewicz I, Loman A, Klement R, Fritsch C, Klymchenko AS, Bunt G, Jovin TM, Arndt-Jovin DJ.

Cytometry A. 2013 Sep;83(9):794-805. doi: 10.1002/cyto.a.22311. Epub 2013 Jul 9.


Differential endocytosis and signaling dynamics of insulin receptor variants IR-A and IR-B.

Giudice J, Leskow FC, Arndt-Jovin DJ, Jovin TM, Jares-Erijman EA.

J Cell Sci. 2011 Mar 1;124(Pt 5):801-11. doi: 10.1242/jcs.076869. Epub 2011 Feb 8. Retraction in: J Cell Sci. 2012 Jun 1;125(Pt 11):2786.


Minimizing light exposure with the programmable array microscope.

Caarls W, Rieger B, De Vries AH, Arndt-Jovin DJ, Jovin TM.

J Microsc. 2011 Jan;241(1):101-10. doi: 10.1111/j.1365-2818.2010.03413.x.


Distribution of resting and ligand-bound ErbB1 and ErbB2 receptor tyrosine kinases in living cells using number and brightness analysis.

Nagy P, Claus J, Jovin TM, Arndt-Jovin DJ.

Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16524-9. doi: 10.1073/pnas.1002642107. Epub 2010 Sep 2.


Targeted cellular delivery of quantum dots loaded on and in biotinylated liposomes.

Sigot V, Arndt-Jovin DJ, Jovin TM.

Bioconjug Chem. 2010 Aug 18;21(8):1465-72. doi: 10.1021/bc100054c.


Specific visualization of glioma cells in living low-grade tumor tissue.

Kantelhardt SR, Caarls W, de Vries AH, Hagen GM, Jovin TM, Schulz-Schaeffer W, Rohde V, Giese A, Arndt-Jovin DJ.

PLoS One. 2010 Jun 30;5(6):e11323. doi: 10.1371/journal.pone.0011323.


Induction of terminal differentiation in melanoma cells on downregulation of beta-amyloid precursor protein.

Botelho MG, Wang X, Arndt-Jovin DJ, Becker D, Jovin TM.

J Invest Dermatol. 2010 May;130(5):1400-10. doi: 10.1038/jid.2009.296. Epub 2009 Sep 17.


Tumor-targeted quantum dots can help surgeons find tumor boundaries.

Arndt-Jovin DJ, Kantelhardt SR, Caarls W, de Vries AH, Giese A, Jovin Ast TM.

IEEE Trans Nanobioscience. 2009 Mar;8(1):65-71. doi: 10.1109/TNB.2009.2016548. Epub 2009 Mar 16.


Fluorescence recovery after photobleaching and photoconversion in multiple arbitrary regions of interest using a programmable array microscope.

Hagen GM, Caarls W, Lidke KA, De Vries AH, Fritsch C, Barisas BG, Arndt-Jovin DJ, Jovin TM.

Microsc Res Tech. 2009 Jun;72(6):431-40. doi: 10.1002/jemt.20686.


Two-photon near- and far-field fluorescence microscopy with continuous-wave excitation.

Hell SW, Booth M, Wilms S, Schnetter CM, Kirsch AK, Arndt-Jovin DJ, Jovin TM.

Opt Lett. 1998 Aug 1;23(15):1238-40.


Quantitative single particle tracking of NGF-receptor complexes: transport is bidirectional but biased by longer retrograde run lengths.

Echarte MM, Bruno L, Arndt-Jovin DJ, Jovin TM, Pietrasanta LI.

FEBS Lett. 2007 Jun 26;581(16):2905-13. Epub 2007 May 25.


Ligand-conjugated quantum dots monitor antigen uptake and processing by dendritic cells.

Cambi A, Lidke DS, Arndt-Jovin DJ, Figdor CG, Jovin TM.

Nano Lett. 2007 Apr;7(4):970-7. Epub 2007 Mar 28.


Biotin-ligand complexes with streptavidin quantum dots for in vivo cell labeling of membrane receptors.

Lidke DS, Nagy P, Jovin TM, Arndt-Jovin DJ.

Methods Mol Biol. 2007;374:69-79.


Drosophila under the lens: imaging from chromosomes to whole embryos.

Fritsch C, Ploeger G, Arndt-Jovin DJ.

Chromosome Res. 2006;14(4):451-64. Review.


Recombination R-triplex: H-bonds contribution to stability as revealed with minor base substitutions for adenine.

Shchyolkina AK, Kaluzhny DN, Arndt-Jovin DJ, Jovin TM, Zhurkin VB.

Nucleic Acids Res. 2006 Jun 23;34(11):3239-45. Print 2006.


Fluorescence lifetime imaging in an optically sectioning programmable array microscope (PAM).

Hanley QS, Lidke KA, Heintzmann R, Arndt-Jovin DJ, Jovin TM.

Cytometry A. 2005 Oct;67(2):112-8.


Selective photoreactions in a programmable array microscope (PAM): photoinitiated polymerization, photodecaging, and photochromic conversion.

Fulwyler M, Hanley QS, Schnetter C, Young IT, Jares-Erijman EA, Arndt-Jovin DJ, Jovin TM.

Cytometry A. 2005 Oct;67(2):68-75.


Reaching out for signals: filopodia sense EGF and respond by directed retrograde transport of activated receptors.

Lidke DS, Lidke KA, Rieger B, Jovin TM, Arndt-Jovin DJ.

J Cell Biol. 2005 Aug 15;170(4):619-26.


Polycomb group protein complexes exchange rapidly in living Drosophila.

Ficz G, Heintzmann R, Arndt-Jovin DJ.

Development. 2005 Sep;132(17):3963-76. Epub 2005 Aug 3. Erratum in: Development. 2005 Sep;132(17):4016.


Parallel DNA double helices incorporating isoG or m5isoC bases studied by FTIR, CD and molecular modeling.

Geinguenaud F, Mondragon-Sanchez JA, Liquier J, Shchyolkina AK, Klement R, Arndt-Jovin DJ, Jovin TM, Taillandier E.

Spectrochim Acta A Mol Biomol Spectrosc. 2005 Feb;61(4):579-87.


One- and two-photon photoactivation of a paGFP-fusion protein in live Drosophila embryos.

Post JN, Lidke KA, Rieger B, Arndt-Jovin DJ.

FEBS Lett. 2005 Jan 17;579(2):325-30.


Imaging takes a quantum leap.

Lidke DS, Arndt-Jovin DJ.

Physiology (Bethesda). 2004 Dec;19:322-5. Review.


Formation of an intramolecular triple-stranded DNA structure monitored by fluorescence of 2-aminopurine or 6-methylisoxanthopterin.

Shchyolkina AK, Kaluzhny DN, Borisova OF, Hawkins ME, Jernigan RL, Jovin TM, Arndt-Jovin DJ, Zhurkin VB.

Nucleic Acids Res. 2004 Jan 22;32(2):432-40. Print 2004.


Quantum dot ligands provide new insights into erbB/HER receptor-mediated signal transduction.

Lidke DS, Nagy P, Heintzmann R, Arndt-Jovin DJ, Post JN, Grecco HE, Jares-Erijman EA, Jovin TM.

Nat Biotechnol. 2004 Feb;22(2):198-203. Epub 2004 Jan 4.


Imaging molecular interactions in cells by dynamic and static fluorescence anisotropy (rFLIM and emFRET).

Lidke DS, Nagy P, Barisas BG, Heintzmann R, Post JN, Lidke KA, Clayton AH, Arndt-Jovin DJ, Jovin TM.

Biochem Soc Trans. 2003 Oct;31(Pt 5):1020-7. Review.


The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci.

Ingelfinger D, Arndt-Jovin DJ, Lührmann R, Achsel T.

RNA. 2002 Dec;8(12):1489-501.


Dynamic fluorescence anisotropy imaging microscopy in the frequency domain (rFLIM).

Clayton AH, Hanley QS, Arndt-Jovin DJ, Subramaniam V, Jovin TM.

Biophys J. 2002 Sep;83(3):1631-49.


Fluorescence lifetime imaging: multi-point calibration, minimum resolvable differences, and artifact suppression.

Hanley QS, Subramaniam V, Arndt-Jovin DJ, Jovin TM.

Cytometry. 2001 Apr 1;43(4):248-60.


Protein-free parallel triple-stranded DNA complex formation.

Shchyolkina AK, Timofeev EN, Lysov YP, Florentiev VL, Jovin TM, Arndt-Jovin DJ.

Nucleic Acids Res. 2001 Feb 15;29(4):986-95.


Developmental regulation of DNA-topoisomerases during Drosophila embryogenesis.

Gemkow MJ, Dichter J, Arndt-Jovin DJ.

Exp Cell Res. 2001 Jan 15;262(2):114-21.


Three-dimensional spectral imaging by hadamard transform spectroscopy in a programmable array microscope.

Hanley QS, Verveer PJ, Arndt-Jovin DJ, Jovin TM.

J Microsc. 2000 Jan;197(Pt 1):5-14.


Picosecond multiphoton scanning near-field optical microscopy.

Jenei A, Kirsch AK, Subramaniam V, Arndt-Jovin DJ, Jovin TM.

Biophys J. 1999 Feb;76(2):1092-100.


Continuous wave two-photon scanning near-field optical microscopy.

Kirsch AK, Subramaniam V, Striker G, Schnetter C, Arndt-Jovin DJ, Jovin TM.

Biophys J. 1998 Sep;75(3):1513-21.


Structural hierarchy in the clustering of HLA class I molecules in the plasma membrane of human lymphoblastoid cells.

Damjanovich S, Vereb G, Schaper A, Jenei A, Matkó J, Starink JP, Fox GQ, Arndt-Jovin DJ, Jovin TM.

Proc Natl Acad Sci U S A. 1995 Feb 14;92(4):1122-6.


Visualization of lipid-receptor interactions on single cells by time-resolved imaging fluorescence microscopy.

Gadella TW Jr, Arndt-Jovin DJ, Jovin TM.

J Fluoresc. 1994 Dec;4(4):295-8. doi: 10.1007/BF01881443.


Human 170 kDa and 180 kDa topoisomerases II bind preferentially to curved and left-handed linear DNA.

Bechert T, Diekmann S, Arndt-Jovin DJ.

J Biomol Struct Dyn. 1994 Dec;12(3):605-23.


Raman microspectroscopic study of low-pH-induced changes in DNA structure of polytene chromosomes.

Puppels GJ, Otto C, Greve J, Robert-Nicoud M, Arndt-Jovin DJ, Jovin TM.

Biochemistry. 1994 Mar 22;33(11):3386-95.


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