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Co-inhibition of mTORC1, HDAC and ESR1α retards the growth of triple-negative breast cancer and suppresses cancer stem cells.

Sulaiman A, McGarry S, Lam KM, El-Sahli S, Chambers J, Kaczmarek S, Li L, Addison C, Dimitroulakos J, Arnaout A, Nessim C, Yao Z, Ji G, Song H, Liu S, Xie Y, Gadde S, Li X, Wang L.

Cell Death Dis. 2018 Jul 26;9(8):815. doi: 10.1038/s41419-018-0811-7.


Diabetes Canada Position Statement for People with Types 1 and 2 Diabetes Who Fast During Ramadan.

Bajaj HS, Abouhassan T, Ahsan MR, Arnaout A, Hassanein M, Houlden RL, Khan T, Khandwala H, Verma S.

Can J Diabetes. 2018 Apr 27. pii: S1499-2671(18)30265-X. doi: 10.1016/j.jcjd.2018.04.007. [Epub ahead of print]


Dual inhibition of Wnt and Yes-associated protein signaling retards the growth of triple-negative breast cancer in both mesenchymal and epithelial states.

Sulaiman A, McGarry S, Li L, Jia D, Ooi S, Addison C, Dimitroulakos J, Arnaout A, Nessim C, Yao Z, Ji G, Song H, Gadde S, Li X, Wang L.

Mol Oncol. 2018 Apr;12(4):423-440. doi: 10.1002/1878-0261.12167. Epub 2018 Feb 21.


Training Canadian surgeons in oncoplastic breast surgery: Where do we stand?

Khayat E, Brackstone M, Maxwell J, Hanrahan R, Richardson J, Kapala M, Arnaout A.

Can J Surg. 2017 Dec;60(6):369-371.


What we learned in kindergarten: five tips for collaboration in oncology.

Arnaout A, Joy AA, Juliao M, Clemons M.

Curr Oncol. 2017 Oct;24(5):e437-e440. doi: 10.3747/co.24.3675. Epub 2017 Oct 25. No abstract available.


Training oncoplastic breast surgeons: the Canadian fellowship experience.

Maxwell J, Arnaout A, Hanrahan R, Brackstone M.

Curr Oncol. 2017 Oct;24(5):e394-e402. doi: 10.3747/co.24.3554. Epub 2017 Oct 25.


Radioactive Seed Localization Versus Wire-Guided Localization for Nonpalpable Breast Cancer: A Cost and Operating Room Efficiency Analysis.

Zhang Y, Seely J, Cordeiro E, Hefler J, Thavorn K, Mahajan M, Domina S, Aro J, Ibrahim AM, Arnaout A, Gravel D, Nessim C.

Ann Surg Oncol. 2017 Nov;24(12):3567-3573. doi: 10.1245/s10434-017-6084-z. Epub 2017 Sep 14.


Insights Into the Recognition and Management of SGLT2-Inhibitor-Associated Ketoacidosis: It's Not Just Euglycemic Diabetic Ketoacidosis.

Dizon S, Keely EJ, Malcolm J, Arnaout A.

Can J Diabetes. 2017 Oct;41(5):499-503. doi: 10.1016/j.jcjd.2017.05.004. Epub 2017 Aug 7. No abstract available.


Physician "out of office" alert: does it work?

Clemons M, Joy AA, Hilton J, Arnaout A, Brackstone M, Wheatley-Price P, Stober C, Dinniwell R, Mazzarello S, da Costa M, Hutton B.

Curr Oncol. 2017 Jun;24(3):e176-e179. doi: 10.3747/co.24.3548. Epub 2017 Jun 27. No abstract available.


How do the characteristics of breast cancer diagnostic assessment programmes influence service delivery: A mixed methods study.

Gagliardi AR, Honein-AbouHaidar G, Stuart-McEwan T, Smylie J, Arnaout A, Seely J, Wright FC, Dobrow MJ, Brouwers MC, Bukhanov K, McCready DR.

Eur J Cancer Care (Engl). 2018 Mar;27(2):e12727. doi: 10.1111/ecc.12727. Epub 2017 Jun 21.


The Southwest UK Burns Network (SWUK) experience of electronic cigarette explosions and review of literature.

Arnaout A, Khashaba H, Dobbs T, Dewi F, Pope-Jones S, Sack A, Estela C, Nguyen D.

Burns. 2017 Jun;43(4):e1-e6. doi: 10.1016/j.burns.2017.01.008. Epub 2017 Apr 12. Review.


Re: Burn injuries from exploding electronic cigarette batteries: An emerging public health hazard.

Arnaout A, Dewi F, Nguyen D.

J Plast Reconstr Aesthet Surg. 2017 Jul;70(7):981-982. doi: 10.1016/j.bjps.2017.02.021. Epub 2017 Feb 28. No abstract available.


The Web-based CanMEDS Resident Learning Portfolio Project (WEBCAM): how we got started.

Glen P, Balaa F, Momoli F, Martin L, Found D, Arnaout A.

Can J Surg. 2016 Dec;59(6):425-426.


Beware flammable fingernails. case report: synthetic fingernails result in full thickness burn and terminalisation.

Arnaout A, Cubitt J, Nguyen D.

Ann Burns Fire Disasters. 2016 Jun 30;29(2):144-145.


Both bulk and cancer stem cell subpopulations in triple-negative breast cancer are susceptible to Wnt, HDAC, and ERα coinhibition.

Sulaiman A, Sulaiman B, Khouri L, McGarry S, Nessim C, Arnaout A, Li X, Addison C, Dimitroulakos J, Wang L.

FEBS Lett. 2016 Dec;590(24):4606-4616. doi: 10.1002/1873-3468.12496. Epub 2016 Dec 9.


Novel Methodology for Comparing Standard-of-Care Interventions in Patients With Cancer.

Hilton J, Mazzarello S, Fergusson D, Joy AA, Robinson A, Arnaout A, Hutton B, Vandermeer L, Clemons M.

J Oncol Pract. 2016 Dec;12(12):e1016-e1024. Epub 2016 Sep 30.


Estrogen, progesterone, and HER2/neu receptor discordance between primary and metastatic breast tumours-a review.

Yeung C, Hilton J, Clemons M, Mazzarello S, Hutton B, Haggar F, Addison CL, Kuchuk I, Zhu X, Gelmon K, Arnaout A.

Cancer Metastasis Rev. 2016 Sep;35(3):427-37. doi: 10.1007/s10555-016-9631-3. Review.


Can the referring surgeon enhance accrual of breast cancer patients to medical and radiation oncology trials? The ENHANCE study.

Arnaout A, Kuchuk I, Bouganim N, Pond G, Verma S, Segal R, Dent S, Gertler S, Song X, Kanji F, Clemons M.

Curr Oncol. 2016 Jun;23(3):e276-9. doi: 10.3747/co.23.2394. Epub 2016 Jun 9.


Carbon Nanotubes in Biomedical Applications: Factors, Mechanisms, and Remedies of Toxicity.

Alshehri R, Ilyas AM, Hasan A, Arnaout A, Ahmed F, Memic A.

J Med Chem. 2016 Sep 22;59(18):8149-67. doi: 10.1021/acs.jmedchem.5b01770. Epub 2016 May 27. Review.


Cost implications of unwarranted imaging for distant metastasis in women with early-stage breast cancer in Ontario.

Thavorn K, Wang Z, Fergusson D, van Katwyk S, Arnaout A, Clemons M.

Curr Oncol. 2016 Feb;23(Suppl 1):S52-5. doi: 10.3747/co.23.2977. Epub 2016 Feb 29.


Issues Affecting the Loco-regional and Systemic Management of Patients with Invasive Lobular Carcinoma of the Breast.

Jacobs C, Clemons M, Addison C, Robertson S, Arnaout A.

Breast J. 2016 Jan-Feb;22(1):45-53. doi: 10.1111/tbj.12520. Review.


Providing mentorship support to general surgery residents: a model for structured group facilitation.

Champion C, Bennett S, Carver D, El Tawil K, Fabbro S, Howatt N, Noei F, Rae R, Haggar F, Arnaout A.

Can J Surg. 2015 Dec;58(6):372-3. Review.


Pneumocystis jiroveci pneumonia (PCP) in patients receiving neoadjuvant and adjuvant anthracycline-based chemotherapy for breast cancer: incidence and risk factors.

Waks AG, Tolaney SM, Galar A, Arnaout A, Porter JB, Marty FM, Winer EP, Hammond SP, Baden LR.

Breast Cancer Res Treat. 2015 Nov;154(2):359-67. doi: 10.1007/s10549-015-3573-2. Epub 2015 Sep 29.


Use of Preoperative Magnetic Resonance Imaging for Breast Cancer: A Canadian Population-Based Study.

Arnaout A, Catley C, Booth CM, McInnes M, Graham I, Kumar V, Simos D, Van Walraven C, Clemons M.

JAMA Oncol. 2015 Dec;1(9):1238-50. doi: 10.1001/jamaoncol.2015.3018.


Invasive Pleomorphic Lobular Carcinoma of the Breast: Pathologic, Clinical, and Therapeutic Considerations.

Al-Baimani K, Bazzarelli A, Clemons M, Robertson SJ, Addison C, Arnaout A.

Clin Breast Cancer. 2015 Dec;15(6):421-5. doi: 10.1016/j.clbc.2015.06.010. Epub 2015 Jun 22. Review.


Imaging for distant metastases in women with early-stage breast cancer: a population-based cohort study.

Simos D, Catley C, van Walraven C, Arnaout A, Booth CM, McInnes M, Fergusson D, Dent S, Clemons M.

CMAJ. 2015 Sep 8;187(12):E387-97. doi: 10.1503/cmaj.150003. Epub 2015 Jun 22.


Re: Chyle leak after axillary node dissection.

Javed MU, Arnaout A, Josty I.

J Plast Reconstr Aesthet Surg. 2015 Aug;68(8):e157. doi: 10.1016/j.bjps.2015.05.029. Epub 2015 Jun 9. No abstract available.


Treatment choices for patients with invasive lobular breast cancer: a doctor survey.

Jacobs C, Ibrahim MF, Clemons M, Hutton B, Simos D, Caudrelier JM, Graham ID, Smith S, Addison C, Arnaout A.

J Eval Clin Pract. 2015 Aug;21(4):740-8. doi: 10.1111/jep.12379. Epub 2015 Jun 9.


Alemtuzumab Induced Thyroid Disease in Multiple Sclerosis: A Review and Approach to Management.

Mahzari M, Arnaout A, Freedman MS.

Can J Neurol Sci. 2015 Sep;42(5):284-91. doi: 10.1017/cjn.2015.48. Epub 2015 May 20. Review.


Immune checkpoint inhibitor therapy associated hypophysitis.

Mahzari M, Liu D, Arnaout A, Lochnan H.

Clin Med Insights Endocrinol Diabetes. 2015 Mar 25;8:21-8. doi: 10.4137/CMED.S22469. eCollection 2015. Review.


Neoadjuvant endocrine therapy and window of opportunity trials: new standards in the treatment of breast cancer?

Levasseur N, Clemons M, Hilton J, Addison C, Robertson S, Ibrahim M, Arnaout A.

Minerva Chir. 2015 Jun;70(3):181-93. Epub 2015 Mar 4. Review.


Nipple discharge.

Mazzarello S, Arnaout A.

CMAJ. 2015 May 19;187(8):599. doi: 10.1503/cmaj.140633. Epub 2015 Mar 2. No abstract available.


Evaluating the feasibility of performing window of opportunity trials in breast cancer.

Arnaout A, Robertson S, Kuchuk I, Simos D, Pond GR, Addison CL, Namazi M, Clemons M.

Int J Surg Oncol. 2015;2015:785793. doi: 10.1155/2015/785793. Epub 2015 Jan 20.


Publishing clinical research: ten pearls for oncology trainees and junior oncologists.

Mazzarello S, Clemons M, Jacobs C, Arnaout A, Fralick M.

Curr Oncol. 2015 Feb;22(1):e1-5. doi: 10.3747/co.22.2258. No abstract available.


Concurrent chemoradiotherapy for locally advanced breast cancer-time for a new paradigm?

Mandilaras V, Bouganim N, Spayne J, Dent R, Arnaout A, Boileau JF, Brackstone M, Meterissian S, Clemons M.

Curr Oncol. 2015 Feb;22(1):25-32. doi: 10.3747/co.21.2043. Review.


Sentinel node biopsy after neoadjuvant chemotherapy in biopsy-proven node-positive breast cancer: the SN FNAC study.

Boileau JF, Poirier B, Basik M, Holloway CM, Gaboury L, Sideris L, Meterissian S, Arnaout A, Brackstone M, McCready DR, Karp SE, Trop I, Lisbona A, Wright FC, Younan RJ, Provencher L, Patocskai E, Omeroglu A, Robidoux A.

J Clin Oncol. 2015 Jan 20;33(3):258-64. doi: 10.1200/JCO.2014.55.7827. Epub 2014 Dec 1.


Imaging for metastatic disease in patients with newly diagnosed breast cancer: are doctor's perceptions in keeping with the guidelines?

Simos D, Hutton B, Graham ID, Arnaout A, Caudrelier JM, Clemons M.

J Eval Clin Pract. 2015 Feb;21(1):67-73. doi: 10.1111/jep.12240. Epub 2014 Oct 14.


Sensory recovery after primary repair of palmar digital nerves using a Revolnerv(®) collagen conduit: a prospective series of 27 cases.

Arnaout A, Fontaine C, Chantelot C.

Chir Main. 2014 Sep;33(4):279-85. doi: 10.1016/j.main.2014.05.002. Epub 2014 Jun 18.


Breast MALToma.

Qian Y, Seely J, Hakim S, Jamison BM, Arnaout A.

Breast J. 2014 Sep-Oct;20(5):551-2. doi: 10.1111/tbj.12313. Epub 2014 Jul 23. No abstract available.


Juvenile papillomatosis: a case report and literature review.

Lad S, Seely J, Elmaadawi M, Peddle S, Perkins G, Robertson S, Ibach K, Haggar F, Arnaout A.

Clin Breast Cancer. 2014 Oct;14(5):e103-5. doi: 10.1016/j.clbc.2014.03.003. Epub 2014 Jun 2. Review. No abstract available.


Patient perceptions and expectations regarding imaging for metastatic disease in early stage breast cancer.

Simos D, Hutton B, Graham ID, Arnaout A, Caudrelier JM, Mazzarello S, Clemons M.

Springerplus. 2014 Apr 5;3:176. doi: 10.1186/2193-1801-3-176. eCollection 2014.


Re: "Decreased risk of celiac disease in patients with Helicobacter pylori colonization".

Mooney PD, Evans KE, Barrett SM, Arnaout A, Sanders DS.

Am J Epidemiol. 2014 May 15;179(10):1275. doi: 10.1093/aje/kwu054. Epub 2014 Apr 3. No abstract available.


Neoadjuvant endocrine treatment for breast cancer: from bedside to bench and back again?

Saleh RR, Bouganim N, Hilton J, Arnaout A, Clemons M.

Curr Oncol. 2014 Feb;21(1):e122-8. doi: 10.3747/co.21.1627.


Surgical considerations in locally advanced breast cancer patients receiving neoadjuvant chemotherapy.

Arnaout A, Boileau JF, Brackstone M.

Curr Opin Support Palliat Care. 2014 Mar;8(1):39-45. doi: 10.1097/SPC.0000000000000031. Review.


Primary endocrine therapy as an approach for patients with localized breast cancer deemed not to be surgical candidates.

Hilton J, Arnaout A, Clemons M.

Curr Opin Support Palliat Care. 2014 Mar;8(1):53-8. doi: 10.1097/SPC.0000000000000026. Review.


Do alternative methods of measuring tumor size, including consideration of multicentric/multifocal disease, enhance prognostic information beyond TNM staging in women with early stage breast cancer: an analysis of the NCIC CTG MA.5 and MA.12 clinical trials.

Hilton JF, Bouganim N, Dong B, Chapman JW, Arnaout A, O'Malley F, Gelmon KA, Yerushalmi R, Levine MN, Bramwell VH, Whelan TJ, Pritchard KI, Shepherd LE, Clemons M.

Breast Cancer Res Treat. 2013 Nov;142(1):143-51. doi: 10.1007/s10549-013-2714-8. Epub 2013 Oct 11.


Improving breast diagnostic services with a Rapid Access Diagnostic and Support (RADS) program.

Arnaout A, Smylie J, Seely J, Robertson S, Knight K, Shin S, Ramsey T, Mallick R, Watters J.

Ann Surg Oncol. 2013 Oct;20(10):3335-40. doi: 10.1245/s10434-013-3120-5. Epub 2013 Aug 22.


Loss of expression and promoter methylation of SLIT2 are associated with sessile serrated adenoma formation.

Beggs AD, Jones A, Shepherd N, Arnaout A, Finlayson C, Abulafi AM, Morton DG, Matthews GM, Hodgson SV, Tomlinson IP.

PLoS Genet. 2013 May;9(5):e1003488. doi: 10.1371/journal.pgen.1003488. Epub 2013 May 9.


Clinical outcomes and treatment practice patterns of patients with HER2-positive metastatic breast cancer in the post-trastuzumab era.

Olson EM, Najita JS, Sohl J, Arnaout A, Burstein HJ, Winer EP, Lin NU.

Breast. 2013 Aug;22(4):525-31. doi: 10.1016/j.breast.2012.12.006. Epub 2013 Jan 23.


Excision of the primary tumour in patients with metastatic breast cancer: a clinical dilemma.

Samiee S, Berardi P, Bouganim N, Vandermeer L, Arnaout A, Dent S, Mirsky D, Chasen M, Caudrelier JM, Clemons M.

Curr Oncol. 2012 Aug;19(4):e270-9. doi: 10.3747/co.19.974.

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