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Items: 1 to 50 of 224

1.

Inosine monophosphate dehydrogenase activity in paediatrics: age-related regulation and response to mycophenolic acid.

Rother A, Glander P, Vitt E, Czock D, von Ahsen N, Armstrong VW, Oellerich M, Budde K, Feneberg R, Tönshoff B, Weber LT.

Eur J Clin Pharmacol. 2012 Jun;68(6):913-22. doi: 10.1007/s00228-011-1203-4. Epub 2012 Jan 25.

PMID:
22274404
2.

Proteomics approach to identify the interacting partners of cellular prion protein and characterization of Rab7a interaction in neuronal cells.

Zafar S, von Ahsen N, Oellerich M, Zerr I, Schulz-Schaeffer WJ, Armstrong VW, Asif AR.

J Proteome Res. 2011 Jul 1;10(7):3123-35. doi: 10.1021/pr2001989. Epub 2011 Jun 7.

PMID:
21604690
3.

Lipid-apheresis improves microcirculation of the upper limbs.

Rossenbach J, Mueller GA, Lange K, Armstrong VW, Schmitto JD, Hintze E, Helfmann J, Konstantinides S, Koziolek MJ.

J Clin Apher. 2011;26(4):167-73. doi: 10.1002/jca.20285. Epub 2011 Apr 15.

PMID:
21500250
4.

How delayed graft function impacts exposure to mycophenolic acid in patients after renal transplantation.

van Gelder T, Silva HT, de Fijter H, Budde K, Kuypers D, Mamelok RD, Armstrong VW, Oellerich M.

Ther Drug Monit. 2011 Apr;33(2):155-64. doi: 10.1097/FTD.0b013e31820c0a96.

PMID:
21383657
5.

Amyloid-β 1-42 levels are modified by apolipoprotein E ε4 in Creutzfeldt-Jakob disease in a similar manner as in Alzheimer's disease.

Varges D, Jung K, Gawinecka J, Heinemann U, Schmitz M, von Ahsen N, Krasnianski A, Armstrong VW, Zerr I.

J Alzheimers Dis. 2011;23(4):717-26. doi: 10.3233/JAD-2010-101527.

PMID:
21157024
6.

Population pharmacokinetics of mycophenolic acid in pediatric renal transplant patients using parametric and nonparametric approaches.

Prémaud A, Weber LT, Tönshoff B, Armstrong VW, Oellerich M, Urien S, Marquet P, Rousseau A.

Pharmacol Res. 2011 Mar;63(3):216-24. doi: 10.1016/j.phrs.2010.10.017. Epub 2010 Nov 5.

7.

Mycophenolic acid displays IMPDH-dependent and IMPDH-independent effects on renal fibroblast proliferation and function.

Petrova DT, Brandhorst G, Brehmer F, Gross O, Oellerich M, Armstrong VW.

Ther Drug Monit. 2010 Aug;32(4):405-12. doi: 10.1097/FTD.0b013e3181e44260.

PMID:
20592645
8.

Differential proteome and phosphoproteome signatures in human T-lymphoblast cells induced by sirolimus.

Schultze FC, Petrova DT, Oellerich M, Armstrong VW, Asif AR.

Cell Prolif. 2010 Aug;43(4):396-404. doi: 10.1111/j.1365-2184.2010.00690.x.

PMID:
20590665
9.

Retrospective analysis of long-term lipid apheresis at a single center.

Koziolek MJ, Hennig U, Zapf A, Bramlage C, Grupp C, Armstrong VW, Strutz F, Müller GA.

Ther Apher Dial. 2010 Apr;14(2):143-52. doi: 10.1111/j.1744-9987.2009.00747.x.

PMID:
20438535
10.

Low-density lipoprotein apheresis decreases ferritin, transferrin and vitamin B12, which may cause anemia in serially treated patients.

Bramlage CP, Armstrong VW, Zapf A, Bramlage P, Mueller GA, Koziolek MJ.

Ther Apher Dial. 2010 Apr;14(2):136-42. doi: 10.1111/j.1744-9987.2009.00715.x.

PMID:
20438534
11.

Mycophenolic acid predose concentrations and renal function in a mouse model for progressive renal fibrosis.

Brandhorst G, Brehmer F, Petrova DT, Gross O, Miosge N, Armstrong VW, Oellerich M.

Ther Drug Monit. 2010 Feb;32(1):73-8. doi: 10.1097/FTD.0b013e3181c91fc4.

PMID:
20042922
12.

Thirty years of Therapeutic Drug Monitoring.

Armstrong VW.

Ther Drug Monit. 2009 Dec;31(6):669. doi: 10.1097/FTD.0b013e3181c73b3a. No abstract available.

PMID:
19935360
13.

The acyl glucuronide metabolite of mycophenolic acid induces tubulin polymerization in vitro.

Feichtiger H, Wieland E, Armstrong VW, Shipkova M.

Clin Biochem. 2010 Jan;43(1-2):208-13. doi: 10.1016/j.clinbiochem.2009.08.023. Epub 2009 Sep 8.

PMID:
19744471
14.

Prenatal programming of metabolic syndrome in the common marmoset is associated with increased expression of 11beta-hydroxysteroid dehydrogenase type 1.

Nyirenda MJ, Carter R, Tang JI, de Vries A, Schlumbohm C, Hillier SG, Streit F, Oellerich M, Armstrong VW, Fuchs E, Seckl JR.

Diabetes. 2009 Dec;58(12):2873-9. doi: 10.2337/db09-0873. Epub 2009 Aug 31.

15.

Increased mycophenolic acid exposure in stable kidney transplant recipients on tacrolimus as compared with those on sirolimus: implications for pharmacokinetics.

Braun F, Schöcklmann H, Ziegler E, Kunzendorf U, Armstrong VW, Renders L.

Clin Pharmacol Ther. 2009 Oct;86(4):411-5. doi: 10.1038/clpt.2009.129. Epub 2009 Jul 15.

PMID:
19606088
16.

T-786C polymorphism of the NOS-3 gene and the endothelial cell response to fluid shear stress-a proteome analysis.

Asif AR, Oellerich M, Armstrong VW, Hecker M, Cattaruzza M.

J Proteome Res. 2009 Jun;8(6):3161-8. doi: 10.1021/pr800998k.

PMID:
19320461
17.

Pharmacokinetics of mycophenolic acid and its glucuronide metabolites in stable adult liver transplant recipients with renal dysfunction on a low-dose calcineurin inhibitor regimen and mycophenolate mofetil.

Beckebaum S, Armstrong VW, Cicinnati VR, Streit F, Klein CG, Gerken G, Paul A, Oellerich M.

Ther Drug Monit. 2009 Apr;31(2):205-10. doi: 10.1097/FTD.0b013e31819743d9.

PMID:
19307937
18.

Differential proteomic analysis of lymphocytes treated with mycophenolic acid reveals caspase 3-induced cleavage of rho GDP dissociation inhibitor 2.

Heller T, Asif AR, Petrova DT, Doncheva Y, Wieland E, Oellerich M, Shipkova M, Armstrong VW.

Ther Drug Monit. 2009 Apr;31(2):211-7. doi: 10.1097/FTD.0b013e318196fb73.

PMID:
19214148
19.

Opportunities to optimize tacrolimus therapy in solid organ transplantation: report of the European consensus conference.

Wallemacq P, Armstrong VW, Brunet M, Haufroid V, Holt DW, Johnston A, Kuypers D, Le Meur Y, Marquet P, Oellerich M, Thervet E, Toenshoff B, Undre N, Weber LT, Westley IS, Mourad M.

Ther Drug Monit. 2009 Apr;31(2):139-52. doi: 10.1097/FTD.0b013e318198d092.

PMID:
19177031
20.

Regulation of IL2 and NUCB1 in mononuclear cells treated with acyl glucuronide of mycophenolic acid reveals effects independent of inosine monophosphate dehydrogenase inhibition.

Petrova DT, Heller T, Hitt R, Wieland E, Oellerich M, Armstrong VW, Shipkova M.

Ther Drug Monit. 2009 Feb;31(1):31-41. doi: 10.1097/FTD.0b013e318192693e.

PMID:
19065122
21.

Long-term pharmacokinetics of mycophenolic acid in pediatric renal transplant recipients over 3 years posttransplant.

Weber LT, Hoecker B, Armstrong VW, Oellerich M, Tönshoff B.

Ther Drug Monit. 2008 Oct;30(5):570-5. doi: 10.1097/FTD.0b013e31818752d9.

PMID:
18758392
22.

Expression of chloride intracellular channel protein 1 (CLIC1) and tumor protein D52 (TPD52) as potential biomarkers for colorectal cancer.

Petrova DT, Asif AR, Armstrong VW, Dimova I, Toshev S, Yaramov N, Oellerich M, Toncheva D.

Clin Biochem. 2008 Oct;41(14-15):1224-36. doi: 10.1016/j.clinbiochem.2008.07.012. Epub 2008 Jul 30.

PMID:
18710659
23.

AcylMPAG plasma concentrations and mycophenolic acid-related side effects in patients undergoing renal transplantation are not related to the UGT2B7-840G>A gene polymorphism.

van Agteren M, Armstrong VW, van Schaik RH, de Fijter H, Hartmann A, Zeier M, Budde K, Kuypers D, Pisarski P, Le Meur Y, van der Werf M, Mamelok RD, Oellerich M, van Gelder T.

Ther Drug Monit. 2008 Aug;30(4):439-44. doi: 10.1097/FTD.0b013e318180c709.

PMID:
18641546
24.

Physiological role of the cellular prion protein (PrPc): protein profiling study in two cell culture systems.

Ramljak S, Asif AR, Armstrong VW, Wrede A, Groschup MH, Buschmann A, Schulz-Schaeffer W, Bodemer W, Zerr I.

J Proteome Res. 2008 Jul;7(7):2681-95. doi: 10.1021/pr7007187. Epub 2008 Jun 7.

PMID:
18537284
25.

Effect of the antioxidant idebenone on adverse events under mycophenolate mofetil therapy in a rat model.

Heller T, Geide A, Bonitz U, Wegner U, Gröne HJ, Armstrong VW, Oellerich M.

Transplantation. 2008 Mar 15;85(5):739-47. doi: 10.1097/TP.0b013e3181664e54.

PMID:
18337669
26.

Everolimus exposure in cardiac transplant recipients is influenced by concomitant calcineurin inhibitor.

Brandhorst G, Tenderich G, Zittermann A, Oezpeker C, Koerfer R, Oellerich M, Armstrong VW.

Ther Drug Monit. 2008 Feb;30(1):113-6. doi: 10.1097/FTD.0b013e318161a335.

PMID:
18223473
27.

Characterization of the inosine triphosphatase (ITPA) gene: haplotype structure, haplotype-phenotype correlation and promoter function.

von Ahsen N, Oellerich M, Armstrong VW.

Ther Drug Monit. 2008 Feb;30(1):16-22. doi: 10.1097/FTD.0b013e318161a21a.

PMID:
18223458
28.

ApoE distribution and family history in genetic prion diseases in Germany.

Krasnianski A, von Ahsen N, Heinemann U, Meissner B, Kretzschmar HA, Armstrong VW, Zerr I.

J Mol Neurosci. 2008;34(1):45-50. Epub 2007 Sep 11.

PMID:
18157657
29.

Homocysteine in restless legs syndrome.

Bachmann CG, Guth N, Helmschmied K, Armstrong VW, Paulus W, Happe S.

Sleep Med. 2008 May;9(4):388-92. Epub 2007 Sep 27.

PMID:
17900981
30.

Increased frequency of positive family history of dementia in sporadic CJD.

Krasnianski A, von Ahsen N, Heinemann U, Meissner B, Schulz-Schaeffer WJ, Kretzschmar HA, Armstrong VW, Zerr I.

Neurobiol Aging. 2009 Apr;30(4):615-21. Epub 2007 Sep 5.

PMID:
17822808
31.

Real-time assessment of hepatic function is related to clinical outcome in critically ill patients after polytrauma.

Dresing K, Armstrong VW, Leip CL, Streit F, Burchardi H, Stürmer KM, Oellerich M.

Clin Biochem. 2007 Nov;40(16-17):1194-200. Epub 2007 Jul 18.

PMID:
17707362
32.

Development of the first marmoset-specific DNA microarray (EUMAMA): a new genetic tool for large-scale expression profiling in a non-human primate.

Datson NA, Morsink MC, Atanasova S, Armstrong VW, Zischler H, Schlumbohm C, Dutilh BE, Huynen MA, Waegele B, Ruepp A, de Kloet ER, Fuchs E.

BMC Genomics. 2007 Jun 25;8:190.

33.

Plasma concentrations of mycophenolic acid acyl glucuronide are not associated with diarrhea in renal transplant recipients.

Heller T, van Gelder T, Budde K, de Fijter JW, Kuypers D, Arns W, Schmidt J, Rostaing L, Powis SH, Claesson K, Macphee IA, Pohanka E, Engelmayer J, Brandhorst G, Oellerich M, Armstrong VW.

Am J Transplant. 2007 Jul;7(7):1822-31. Epub 2007 May 26.

34.

Pharmacokinetics of mycophenolate mofetil in hematopoietic stem cell transplant recipients.

van Hest RM, Doorduijn JK, de Winter BC, Cornelissen JJ, Vulto AG, Oellerich M, Löwenberg B, Mathot RA, Armstrong VW, van Gelder T.

Ther Drug Monit. 2007 Jun;29(3):353-60.

PMID:
17529894
35.

Mycophenolic acid (MPA) and its glucuronide metabolites interact with transport systems responsible for excretion of organic anions in the basolateral membrane of the human kidney.

Wolff NA, Burckhardt BC, Burckhardt G, Oellerich M, Armstrong VW.

Nephrol Dial Transplant. 2007 Sep;22(9):2497-503. Epub 2007 May 25.

PMID:
17526543
36.

6-thioguanine nucleotide-adapted azathioprine therapy does not lead to higher remission rates than standard therapy in chronic active crohn disease: results from a randomized, controlled, open trial.

Reinshagen M, Schütz E, Armstrong VW, Behrens C, von Tirpitz C, Stallmach A, Herfarth H, Stein J, Bias P, Adler G, Shipkova M, Kruis W, Oellerich M, von Ahsen N.

Clin Chem. 2007 Jul;53(7):1306-14. Epub 2007 May 10.

37.

The role of therapeutic drug monitoring in individualizing immunosuppressive drug therapy: recent developments.

Oellerich M, Armstrong VW.

Ther Drug Monit. 2006 Dec;28(6):720-5. Review. No abstract available.

PMID:
17164686
38.

Marmoset CYP3A21, a model for human CYP3A4: protein expression and functional characterization of the promoter.

Koehler SC, Von Ahsen N, Schlumbohm C, Asif AR, Goedtel-Armbrust U, Oellerich M, Wojnowski L, Armstrong VW.

Xenobiotica. 2006 Dec;36(12):1210-26.

PMID:
17162468
39.

Rifampin induces alterations in mycophenolic acid glucuronidation and elimination: implications for drug exposure in renal allograft recipients.

Naesens M, Kuypers DR, Streit F, Armstrong VW, Oellerich M, Verbeke K, Vanrenterghem Y.

Clin Pharmacol Ther. 2006 Nov;80(5):509-21.

PMID:
17112807
40.

Proteins identified as targets of the acyl glucuronide metabolite of mycophenolic acid in kidney tissue from mycophenolate mofetil treated rats.

Asif AR, Armstrong VW, Voland A, Wieland E, Oellerich M, Shipkova M.

Biochimie. 2007 Mar;89(3):393-402. Epub 2006 Oct 16.

PMID:
17069946
41.

AmpliChip CYP450 GeneChip: a new gene chip that allows rapid and accurate CYP2D6 genotyping.

Heller T, Kirchheiner J, Armstrong VW, Luthe H, Tzvetkov M, Brockmöller J, Oellerich M.

Ther Drug Monit. 2006 Oct;28(5):673-7.

PMID:
17038884
42.

Validation of an abbreviated pharmacokinetic profile for the estimation of mycophenolic acid exposure in pediatric renal transplant recipients.

Weber LT, Hoecker B, Armstrong VW, Oellerich M, Tönshoff B.

Ther Drug Monit. 2006 Oct;28(5):623-31.

PMID:
17038876
43.

Quantification by liquid chromatography tandem mass spectrometry of mycophenolic acid and its phenol and acyl glucuronide metabolites.

Brandhorst G, Streit F, Goetze S, Oellerich M, Armstrong VW.

Clin Chem. 2006 Oct;52(10):1962-4. Epub 2006 Aug 24.

44.

Mycophenolate mofetil in organ transplantation: focus on metabolism, safety and tolerability.

Shipkova M, Armstrong VW, Oellerich M, Wieland E.

Expert Opin Drug Metab Toxicol. 2005 Oct;1(3):505-26. Review.

PMID:
16863458
45.

Differential expression of major histocompatibility complex class I molecules in the brain of a New World monkey, the common marmoset (Callithrix jacchus).

Rölleke U, Flügge G, Plehm S, Schlumbohm C, Armstrong VW, Dressel R, Uchanska-Ziegler B, Ziegler A, Fuchs E, Czéh B, Walter L.

J Neuroimmunol. 2006 Jul;176(1-2):39-50. Epub 2006 Jun 5.

PMID:
16750573
46.

Arginine challenge unravels persistent disturbances of urea cycle and gluconeogenesis in abstinent alcoholics.

Hasselblatt M, Krampe H, Jacobs S, Sindram H, Armstrong VW, Hecker M, Ehrenreich H.

Alcohol Alcohol. 2006 Jul-Aug;41(4):372-8. Epub 2006 May 10.

PMID:
16687468
47.

Biomarkers: the link between therapeutic drug monitoring and pharmacodynamics.

Oellerich M, Barten MJ, Armstrong VW.

Ther Drug Monit. 2006 Feb;28(1):35-8. Review. No abstract available.

PMID:
16418691
48.

Association of inosine triphosphatase 94C>A and thiopurine S-methyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study.

von Ahsen N, Armstrong VW, Behrens C, von Tirpitz C, Stallmach A, Herfarth H, Stein J, Bias P, Adler G, Shipkova M, Oellerich M, Kruis W, Reinshagen M, Schütz E.

Clin Chem. 2005 Dec;51(12):2282-8. Epub 2005 Oct 7. Erratum in: Clin Chem. 2006 Aug;52(8):1628. Schütz, Ekkehard [added].

49.

Contribution of CYP3A5 to the in vitro hepatic clearance of tacrolimus.

Kamdem LK, Streit F, Zanger UM, Brockmöller J, Oellerich M, Armstrong VW, Wojnowski L.

Clin Chem. 2005 Aug;51(8):1374-81. Epub 2005 Jun 10.

50.

Cerebral inflammatory response during and after cardiac surgery.

Mielck F, Ziarkowski A, Hanekop G, Armstrong VW, Hilgers R, Weyland A, Quintel M, Sonntag H.

Eur J Anaesthesiol. 2005 May;22(5):347-52.

PMID:
15918382

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