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Items: 15


A chemical-genetic approach to study G protein regulation of beta cell function in vivo.

Guettier JM, Gautam D, Scarselli M, Ruiz de Azua I, Li JH, Rosemond E, Ma X, Gonzalez FJ, Armbruster BN, Lu H, Roth BL, Wess J.

Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19197-202. doi: 10.1073/pnas.0906593106. Epub 2009 Oct 26.


Remote control of neuronal activity in transgenic mice expressing evolved G protein-coupled receptors.

Alexander GM, Rogan SC, Abbas AI, Armbruster BN, Pei Y, Allen JA, Nonneman RJ, Hartmann J, Moy SS, Nicolelis MA, McNamara JO, Roth BL.

Neuron. 2009 Jul 16;63(1):27-39. doi: 10.1016/j.neuron.2009.06.014.


New insights into the function of M4 muscarinic acetylcholine receptors gained using a novel allosteric modulator and a DREADD (designer receptor exclusively activated by a designer drug).

Nawaratne V, Leach K, Suratman N, Loiacono RE, Felder CC, Armbruster BN, Roth BL, Sexton PM, Christopoulos A.

Mol Pharmacol. 2008 Oct;74(4):1119-31. doi: 10.1124/mol.108.049353. Epub 2008 Jul 15.


Distinct functions of POT1 at telomeres.

Barrientos KS, Kendellen MF, Freibaum BD, Armbruster BN, Etheridge KT, Counter CM.

Mol Cell Biol. 2008 Sep;28(17):5251-64. doi: 10.1128/MCB.00048-08. Epub 2008 Jun 2.


Biochemical analysis of inositol phosphate kinases.

Otto JC, Mulugu S, Fridy PC, Chiou ST, Armbruster BN, Ribeiro AA, York JD.

Methods Enzymol. 2007;434:171-85.


Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand.

Armbruster BN, Li X, Pausch MH, Herlitze S, Roth BL.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5163-8. Epub 2007 Mar 2.


Relating protein pharmacology by ligand chemistry.

Keiser MJ, Roth BL, Armbruster BN, Ernsberger P, Irwin JJ, Shoichet BK.

Nat Biotechnol. 2007 Feb;25(2):197-206.


Mining the receptorome.

Armbruster BN, Roth BL.

J Biol Chem. 2005 Feb 18;280(7):5129-32. Epub 2004 Dec 8. Review. No abstract available.


Inositol diphosphate signaling regulates telomere length.

York SJ, Armbruster BN, Greenwell P, Petes TD, York JD.

J Biol Chem. 2005 Feb 11;280(6):4264-9. Epub 2004 Nov 23.


Rescue of an hTERT mutant defective in telomere elongation by fusion with hPot1.

Armbruster BN, Linardic CM, Veldman T, Bansal NP, Downie DL, Counter CM.

Mol Cell Biol. 2004 Apr;24(8):3552-61.


In vivo regulation of hTERT expression and telomerase activity by androgen.

Guo C, Armbruster BN, Price DT, Counter CM.

J Urol. 2003 Aug;170(2 Pt 1):615-8.


Putative telomere-recruiting domain in the catalytic subunit of human telomerase.

Armbruster BN, Etheridge KT, Broccoli D, Counter CM.

Mol Cell Biol. 2003 May;23(9):3237-46.


The nucleolar localization domain of the catalytic subunit of human telomerase.

Etheridge KT, Banik SS, Armbruster BN, Zhu Y, Terns RM, Terns MP, Counter CM.

J Biol Chem. 2002 Jul 5;277(27):24764-70. Epub 2002 Apr 15.


N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo.

Armbruster BN, Banik SS, Guo C, Smith AC, Counter CM.

Mol Cell Biol. 2001 Nov;21(22):7775-86.


Neurofilament-L is a protein phosphatase-1-binding protein associated with neuronal plasma membrane and post-synaptic density.

Terry-Lorenzo RT, Inoue M, Connor JH, Haystead TA, Armbruster BN, Gupta RP, Oliver CJ, Shenolikar S.

J Biol Chem. 2000 Jan 28;275(4):2439-46.

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