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Items: 1 to 50 of 334

1.

Chemoselective Transformations of Aromatic Methoxymethyl Ethers Using Trialkylsilyl Triflate and 2,2'-Bipyridyl.

Yanagihara M, Ohta R, Murai K, Arisawa M, Fujioka H.

ACS Omega. 2019 May 14;4(5):8465-8471. doi: 10.1021/acsomega.9b00643. eCollection 2019 May 31.

2.

Metal-Free Nitrogen-Containing Polyheterocyclic Near-Infrared (NIR) Absorption Dyes: Synthesis, Absorption Properties, and Theoretical Calculation of Substituted 5-Methylisoindolo[2,1-a]quinolines.

Fujii Y, Suwa Y, Wada Y, Takehara T, Suzuki T, Kawashima Y, Kawashita N, Takagi T, Fujioka H, Arisawa M.

ACS Omega. 2019 Mar 8;4(3):5064-5075. doi: 10.1021/acsomega.9b00315. eCollection 2019 Mar 31.

3.

SF3B2-mediated RNA splicing drives human prostate cancer progression.

Kawamura N, Nimura K, Saga K, Ishibashi A, Kitamura K, Nagano H, Yoshikawa Y, Ishida K, Nonomura N, Arisawa M, Luo J, Kaneda Y.

Cancer Res. 2019 Aug 20. pii: canres.3965.2018. doi: 10.1158/0008-5472.CAN-18-3965. [Epub ahead of print]

PMID:
31431456
4.

Development of Metal Nanoparticle Catalysis toward Drug Discovery.

Arisawa M.

Chem Pharm Bull (Tokyo). 2019;67(8):733-771. doi: 10.1248/cpb.c19-00157. Review.

5.

Pd-Catalyzed Migratory Cycloisomerization of N-Allyl- o-allenylaniline Derivatives.

Ii Y, Hirabayashi S, Yoshioka S, Aoyama H, Murai K, Fujioka H, Arisawa M.

Org Lett. 2019 May 17;21(10):3501-3504. doi: 10.1021/acs.orglett.9b00676. Epub 2019 May 9.

PMID:
31070372
6.

Oxidative Rearrangement of Primary Amines Using PhI(OAc)2 and Cs2CO3.

Yamakoshi W, Arisawa M, Murai K.

Org Lett. 2019 May 3;21(9):3023-3027. doi: 10.1021/acs.orglett.9b00559. Epub 2019 Apr 18.

PMID:
30998017
7.

Design and synthesis of N1,N8-diacetylspermidine analogues having a linker with desired functional groups.

Ohta R, Oguro A, Nishimura K, Murai K, Fujioka H, Arisawa M.

Org Biomol Chem. 2019 Jan 23;17(4):867-875. doi: 10.1039/c8ob02900h.

PMID:
30628612
8.

Tricarboxylic acid cycle activity suppresses acetylation of mitochondrial proteins during early embryonic development in Caenorhabditis elegans.

Hada K, Hirota K, Inanobe A, Kako K, Miyata M, Araoi S, Matsumoto M, Ohta R, Arisawa M, Daitoku H, Hanada T, Fukamizu A.

J Biol Chem. 2019 Mar 1;294(9):3091-3099. doi: 10.1074/jbc.RA118.004726. Epub 2019 Jan 3.

PMID:
30606736
9.

Pd/TiO2-Photocatalyzed Self-Condensation of Primary Amines To Afford Secondary Amines at Ambient Temperature.

Wang LM, Kobayashi K, Arisawa M, Saito S, Naka H.

Org Lett. 2019 Jan 18;21(2):341-344. doi: 10.1021/acs.orglett.8b03271. Epub 2018 Nov 21.

PMID:
30460855
10.

Optically active iodohelicene derivatives exhibit histamine N-methyl transferase inhibitory activity.

Ichinose W, Sawato T, Kitano H, Shinozaki Y, Arisawa M, Saito N, Yoshikawa T, Yamaguchi M.

J Antibiot (Tokyo). 2019 Jun;72(6):476-481. doi: 10.1038/s41429-018-0118-z. Epub 2018 Nov 20.

PMID:
30459457
11.

Design and synthesis of histamine H3/H4 receptor ligands with a cyclopropane scaffold.

Watanabe M, Kobayashi T, Ito Y, Fukuda H, Yamada S, Arisawa M, Shuto S.

Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3630-3633. doi: 10.1016/j.bmcl.2018.10.041. Epub 2018 Oct 26.

PMID:
30385161
12.

Synthesis of Chiral cis-Cyclopropane Bearing Indole and Chromone as Potential TNFα Inhibitors.

Kanada R, Tanabe M, Muromoto R, Sato Y, Kuwahara T, Fukuda H, Arisawa M, Matsuda T, Watanabe M, Shuto S.

J Org Chem. 2018 Aug 3;83(15):7672-7682. doi: 10.1021/acs.joc.8b00466. Epub 2018 Jul 24.

PMID:
30004223
13.

Highly Discriminative and Chemoselective Deprotection/Transformations of Acetals with the Combination of Trialkylsilyl Triflate/2,4,6-Collidine.

Ohta R, Matsumoto N, Ueyama Y, Kuboki Y, Aoyama H, Murai K, Arisawa M, Maegawa T, Fujioka H.

J Org Chem. 2018 Jun 15;83(12):6432-6443. doi: 10.1021/acs.joc.8b00675. Epub 2018 Jun 7.

PMID:
29782161
14.

Cascade Multiple Diels-Alder Reactions of Styrene Derivatives with Maleimide or Maleic Anhydride.

Yoshioka S, Aoyama H, Fujioka H, Arisawa M.

J Org Chem. 2018 Jun 15;83(12):6599-6606. doi: 10.1021/acs.joc.8b00890. Epub 2018 Jun 6.

PMID:
29775066
15.

Palladium-Catalyzed Seven-Membered Silacycle Construction: 1,7-Enyne Hydroxycyclization To Give a Benzosilepine Skeleton.

Takamoto K, Yoshioka S, Fujioka H, Arisawa M.

Org Lett. 2018 Apr 6;20(7):1773-1776. doi: 10.1021/acs.orglett.8b00271. Epub 2018 Mar 12.

PMID:
29528660
16.

Catalytic Method for the Synthesis of C-N-Linked Bi(heteroaryl)s Using Heteroaryl Ethers and N-Benzoyl Heteroarenes.

Tanii S, Arisawa M, Tougo T, Yamaguchi M.

Org Lett. 2018 Apr 6;20(7):1756-1759. doi: 10.1021/acs.orglett.8b00245. Epub 2018 Mar 12.

PMID:
29528237
17.

Rhodium-Catalyzed Insertion Reaction of PhP Group of Pentaphenylcyclopentaphosphine with Acyclic and Cyclic Disulfides.

Arisawa M, Sawahata K, Yamada T, Sarkar D, Yamaguchi M.

Org Lett. 2018 Feb 16;20(4):938-941. doi: 10.1021/acs.orglett.7b03825. Epub 2018 Feb 7.

PMID:
29412679
18.

Ruthenium-Catalyzed 1,6-Aromatic Enamide-Silylalkyne Cycloisomerization: Approach to 2,3-Disubstituted Indoles.

Takamoto K, Ohno S, Hyogo N, Fujioka H, Arisawa M.

J Org Chem. 2017 Aug 18;82(16):8733-8742. doi: 10.1021/acs.joc.7b01288. Epub 2017 Aug 9.

PMID:
28730809
19.

Synthesis of 8-Substituted Analogues of Cyclic ADP-4-Thioribose and Their Unexpected Identification as Ca2+-Mobilizing Full Agonists.

Takano S, Tsuzuki T, Murayama T, Kameda T, Kumaki Y, Sakurai T, Fukuda H, Watanabe M, Arisawa M, Shuto S.

J Med Chem. 2017 Jul 13;60(13):5868-5875. doi: 10.1021/acs.jmedchem.7b00540. Epub 2017 Jul 3.

PMID:
28636353
20.

Concise synthesis of oxacyclic compounds using highly discriminative two-way transformations of α,β-unsaturated esters in the presence of enones.

Morita K, Ohta R, Aoyama H, Yahata K, Arisawa M, Fujioka H.

Chem Commun (Camb). 2017 Jun 16;53(49):6605-6608. doi: 10.1039/c7cc03287k.

PMID:
28580473
21.

One-pot enyne metathesis/Diels-Alder/oxidation to six-membered silacycles with a multi-ring core: discovery of novel fluorophores.

Yoshioka S, Fujii Y, Tsujino H, Uno T, Fujioka H, Arisawa M.

Chem Commun (Camb). 2017 May 30;53(44):5970-5973. doi: 10.1039/c7cc02788e.

PMID:
28480459
22.

Cycloisomerization between Aryl Enol Ether and Silylalkynes under Ruthenium Hydride Catalysis: Synthesis of 2,3-Disubstituted Benzofurans.

Ohno S, Takamoto K, Fujioka H, Arisawa M.

Org Lett. 2017 May 5;19(9):2422-2425. doi: 10.1021/acs.orglett.7b00985. Epub 2017 Apr 24.

PMID:
28436668
23.

Entry to Chiral 1,1,2,3-Tetrasubstituted Arylcyclopropanes by Pd(II)-Catalyzed Arylation via Directing Group-Mediated C(sp3)-H Activation.

Hoshiya N, Kondo M, Fukuda H, Arisawa M, Uenishi J, Shuto S.

J Org Chem. 2017 Mar 3;82(5):2535-2544. doi: 10.1021/acs.joc.6b02935. Epub 2017 Feb 22.

PMID:
28120614
24.

Cyclopropane-Based Peptidomimetics Mimicking Wide-Ranging Secondary Structures of Peptides: Conformational Analysis and Their Use in Rational Ligand Optimization.

Mizuno A, Kameda T, Kuwahara T, Endoh H, Ito Y, Yamada S, Hasegawa K, Yamano A, Watanabe M, Arisawa M, Shuto S.

Chemistry. 2017 Mar 2;23(13):3159-3168. doi: 10.1002/chem.201605312. Epub 2017 Feb 1.

PMID:
28000361
25.

Design and Synthesis of Cyclopropane Congeners of Resolvin E2, an Endogenous Proresolving Lipid Mediator, as Its Stable Equivalents.

Fukuda H, Muromoto R, Takakura Y, Ishimura K, Kanada R, Fushihara D, Tanabe M, Matsubara K, Hirao T, Hirashima K, Abe H, Arisawa M, Matsuda T, Shuto S.

Org Lett. 2016 Dec 16;18(24):6224-6227. Epub 2016 Nov 28.

PMID:
27978690
26.

Rhodium-Catalyzed Synthesis of Unsymmetric Di(heteroaryl) Sulfides Using Heteroaryl Ethers and S-Heteroaryl Thioesters via Heteroarylthio Exchange.

Arisawa M, Tazawa T, Tanii S, Horiuchi K, Yamaguchi M.

J Org Chem. 2017 Jan 6;82(1):804-810. doi: 10.1021/acs.joc.6b02585. Epub 2016 Dec 20.

PMID:
27936692
27.

Rhodium-catalyzed P-P bond exchange reaction of diphosphine disulfides.

Arisawa M, Yamada T, Tanii S, Kawada Y, Hashimoto H, Yamaguchi M.

Chem Commun (Camb). 2016 Nov 15;52(93):13580-13583.

PMID:
27805182
28.

Rhodium-catalyzed transformation of heteroaryl aryl ethers into heteroaryl fluorides.

Arisawa M, Tanii S, Tazawa T, Yamaguchi M.

Chem Commun (Camb). 2016 Sep 15;52(76):11390-11393.

PMID:
27709178
29.

Development of a Sulfur-Modified Glass-Supported Pd Nanoparticle Catalyst for Suzuki-Miyaura Coupling.

Xiao M, Hoshiya N, Fujiki K, Honma T, Tamenori Y, Shuto S, Fujioka H, Arisawa M.

Chem Pharm Bull (Tokyo). 2016;64(8):1154-60. doi: 10.1248/cpb.c16-00261.

30.

Design, Synthesis, and Identification of 4″α-Azidoethyl-cyclic ADP-Carbocyclic-ribose as a Highly Potent Analogue of Cyclic ADP-Ribose, a Ca(2+)-Mobilizing Second Messenger.

Sato T, Watanabe M, Tsuzuki T, Takano S, Murayama T, Sakurai T, Kameda T, Fukuda H, Arisawa M, Shuto S.

J Med Chem. 2016 Aug 11;59(15):7282-6. doi: 10.1021/acs.jmedchem.6b00437. Epub 2016 Jul 20.

PMID:
27391373
31.

Highly Sensitive Measurement of Inositol 1,4,5-Trisphosphate by Using a New Fluorescent Ligand and Ligand Binding Domain Combination.

Oura T, Murata K, Morita T, Nezu A, Arisawa M, Shuto S, Tanimura A.

Chembiochem. 2016 Aug 17;17(16):1509-12. doi: 10.1002/cbic.201600096. Epub 2016 Jun 30.

PMID:
27251449
32.

Identification of a Potent and Selective GPR4 Antagonist as a Drug Lead for the Treatment of Myocardial Infarction.

Fukuda H, Ito S, Watari K, Mogi C, Arisawa M, Okajima F, Kurose H, Shuto S.

ACS Med Chem Lett. 2016 Feb 24;7(5):493-7. doi: 10.1021/acsmedchemlett.6b00014. eCollection 2016 May 12.

33.

Redox Switching of Orthoquinone-Containing Aromatic Compounds with Hydrogen and Oxygen Gas.

Urakawa K, Sumimoto M, Arisawa M, Matsuda M, Ishikawa H.

Angew Chem Int Ed Engl. 2016 Jun 20;55(26):7432-6. doi: 10.1002/anie.201601906. Epub 2016 May 4.

PMID:
27145376
34.

Development of an Enyne Metathesis/Isomerization/Diels-Alder One-Pot Reaction for the Synthesis of a Novel Near-Infrared (NIR) Dye Core.

Yamashita K, Fujii Y, Yoshioka S, Aoyama H, Tsujino H, Uno T, Fujioka H, Arisawa M.

Chemistry. 2015 Nov 23;21(48):17491-4. doi: 10.1002/chem.201502313. Epub 2015 Oct 9.

PMID:
26449517
35.

Stereoselective Construction of 2,7-Disubstituted fused-Bis Tetrahydrofuran Skeletons: Biomimetic-Type Synthesis and Biological Evaluation of (±)- and (-)-Aplysiallene and Their Derivatives.

Yamakawa M, Kurachi T, Yoshikawa Y, Arisawa M, Okino Y, Suzuki K, Fujioka H.

J Org Chem. 2015 Oct 16;80(20):10261-77. doi: 10.1021/acs.joc.5b01882. Epub 2015 Oct 7.

PMID:
26443927
36.

Synthesis of 7-Deaza-cyclic Adenosine-5'-diphosphate-carbocyclic-ribose and Its 7-Bromo Derivative as Intracellular Ca(2+)-Mobilizing Agents.

Takano S, Tsuzuki T, Murayama T, Sakurai T, Fukuda H, Arisawa M, Shuto S.

J Org Chem. 2015 Jul 2;80(13):6619-27. doi: 10.1021/acs.joc.5b00723. Epub 2015 Jun 23.

PMID:
26075947
37.

Characterization of Imidazopyridine Compounds as Negative Allosteric Modulators of Proton-Sensing GPR4 in Extracellular Acidification-Induced Responses.

Tobo A, Tobo M, Nakakura T, Ebara M, Tomura H, Mogi C, Im DS, Murata N, Kuwabara A, Ito S, Fukuda H, Arisawa M, Shuto S, Nakaya M, Kurose H, Sato K, Okajima F.

PLoS One. 2015 Jun 12;10(6):e0129334. doi: 10.1371/journal.pone.0129334. eCollection 2015.

38.

Synthesis of thiiranes by rhodium-catalyzed sulfur addition reaction to reactive alkenes.

Arisawa M, Ichikawa T, Yamaguchi M.

Chem Commun (Camb). 2015 May 25;51(42):8821-4. doi: 10.1039/c5cc01570g.

PMID:
25920577
39.

A palladium-catalyzed addition reaction of aroyl/heteroaroyl acid anhydrides to norbornenes.

Arisawa M, Tanii S, Yamaguchi M.

Chem Commun (Camb). 2014 Dec 14;50(96):15267-70. doi: 10.1039/c4cc07759h.

PMID:
25347414
40.

Conformationally Restricted GABA with Bicyclo[3.1.0]hexane Backbone as the First Highly Selective BGT-1 Inhibitor.

Kobayashi T, Suemasa A, Igawa A, Ide S, Fukuda H, Abe H, Arisawa M, Minami M, Shuto S.

ACS Med Chem Lett. 2014 Jun 16;5(8):889-93. doi: 10.1021/ml500134k. eCollection 2014 Aug 14.

41.

Palladium-nanoparticle-catalyzed 1,7-palladium migration involving C-H activation, followed by intramolecular amination: regioselective synthesis of N1-arylbenzotriazoles and an evaluation of their inhibitory activity toward indoleamine 2,3-dioxygenase.

Takagi K, Al-Amin M, Hoshiya N, Wouters J, Sugimoto H, Shiro Y, Fukuda H, Shuto S, Arisawa M.

J Org Chem. 2014 Jul 3;79(13):6366-71. doi: 10.1021/jo5009838. Epub 2014 Jun 24.

PMID:
24906179
42.

Design, Synthesis, and Chemical and Biological Properties of Cyclic ADP-4-Thioribose as a Stable Equivalent of Cyclic ADP-Ribose.

Tsuzuki T, Takano S, Sakaguchi N, Kudoh T, Murayama T, Sakurai T, Hashii M, Higashida H, Weber K, Guse AH, Kameda T, Hirokawa T, Kumaki Y, Arisawa M, Potter BV, Shuto S.

Messenger (Los Angel). 2014 Jun-Dec;3(1-2):35-51. Epub 2014 Jun 1.

43.

Development of a new class of proteasome inhibitors with an epoxyketone warhead: Rational hybridization of non-peptidic belactosin derivatives and peptide epoxyketones.

Kawamura S, Unno Y, Asai A, Arisawa M, Shuto S.

Bioorg Med Chem. 2014 Jun 15;22(12):3091-5. doi: 10.1016/j.bmc.2014.04.032. Epub 2014 Apr 24.

PMID:
24814885
44.

Ligand-free Suzuki-Miyaura coupling with sulfur-modified gold-supported palladium in the synthesis of a conformationally-restricted cyclopropane compound library with three-dimensional diversity.

Arisawa M, Sato T, Hoshiya N, Al-Amin M, Kogami Y, Shuto S.

ACS Comb Sci. 2014 May 12;16(5):215-20. doi: 10.1021/co4001138. Epub 2014 Apr 3.

PMID:
24697302
45.

Rhodium-catalyzed synthesis of unsymmetrical di(aryl/heteroaryl)methanes using aryl/heteroarylmethyl ketones via CO-C bond cleavage.

Li G, Arisawa M, Yamaguchi M.

Chem Commun (Camb). 2014 Apr 28;50(33):4328-30. doi: 10.1039/c4cc00816b.

PMID:
24643329
46.

Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates.

Kawamura S, Unno Y, Asai A, Arisawa M, Shuto S.

J Med Chem. 2014 Mar 27;57(6):2726-35. doi: 10.1021/jm500045x. Epub 2014 Feb 25.

PMID:
24524217
47.

Rational hopping of a peptidic scaffold into non-peptidic scaffolds: structurally novel potent proteasome inhibitors derived from a natural product, belactosin A.

Kawamura S, Unno Y, Hirokawa T, Asai A, Arisawa M, Shuto S.

Chem Commun (Camb). 2014 Mar 7;50(19):2445-7. doi: 10.1039/c3cc48818g. Epub 2014 Jan 22.

48.
49.

Preparation of chiral bromomethylenecyclopropane and its use in Suzuki-Miyaura coupling: synthesis of the arylmethyl-(Z)-cyclopropane structure core.

Tanabe M, Watanabe M, Hoshiya N, Mizuno A, Fukuda H, Arisawa M, Shuto S.

J Org Chem. 2013 Dec 6;78(23):11714-20. doi: 10.1021/jo401675z. Epub 2013 Nov 20.

PMID:
24206361
50.

Conformational restriction approach to β-secretase (BACE1) inhibitors III: effective investigation of the binding mode by combinational use of X-ray analysis, isothermal titration calorimetry and theoretical calculations.

Yonezawa S, Fujiwara K, Yamamoto T, Hattori K, Yamakawa H, Muto C, Hosono M, Tanaka Y, Nakano T, Takemoto H, Arisawa M, Shuto S.

Bioorg Med Chem. 2013 Nov 1;21(21):6506-22. doi: 10.1016/j.bmc.2013.08.036. Epub 2013 Aug 28.

PMID:
24051074

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