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Symptom Burden and End-of-Life Palliative Treatments during the Last Two Weeks of Life in Patients with Advanced Musculoskeletal Sarcoma.

Kawashima H, Ariizumi T, Yamagishi T, Ogose A, Ikoma M, Hotta T, Endo N.

J Palliat Med. 2019 Feb 14. doi: 10.1089/jpm.2018.0415. [Epub ahead of print]


Targeted Base Editing with CRISPR-Deaminase in Tomato.

Shimatani Z, Ariizumi T, Fujikura U, Kondo A, Ezura H, Nishida K.

Methods Mol Biol. 2019;1917:297-307. doi: 10.1007/978-1-4939-8991-1_22.


Evidence of the functional role of the ethylene receptor genes SlETR4 and SlETR5 in ethylene signal transduction in tomato.

Mubarok S, Hoshikawa K, Okabe Y, Yano R, Tri MD, Ariizumi T, Ezura H.

Mol Genet Genomics. 2018 Oct 31. doi: 10.1007/s00438-018-1505-7. [Epub ahead of print]


Successful resuscitation from cardiac arrest due to histologically revealed tumor embolism following bilateral intramedullary nailing of metastatic femoral lesions.

Fujita Y, Kawashima H, Ariizumi T, Watanabe Y, Aoki K, Imai H, Umezu H, Endo N.

J Orthop Sci. 2018 Oct 4. pii: S0949-2658(18)30256-2. doi: 10.1016/j.jos.2018.09.009. [Epub ahead of print] No abstract available.


Low Infection of Phelipanche aegyptiaca in Micro-Tom Mutants Deficient in CAROTENOIDCLEAVAGE DIOXYGENASE 8.

Hasegawa S, Tsutsumi T, Fukushima S, Okabe Y, Saito J, Katayama M, Shindo M, Yamada Y, Shimomura K, Yoneyama K, Akiyama K, Aoki K, Ariizumi T, Ezura H, Yamaguchi S, Umehara M.

Int J Mol Sci. 2018 Sep 6;19(9). pii: E2645. doi: 10.3390/ijms19092645.


Aberrant Stamen Development is Associated with Parthenocarpic Fruit Set Through Up-Regulation of Gibberellin Biosynthesis in Tomato.

Okabe Y, Yamaoka T, Ariizumi T, Ushijima K, Kojima M, Takebayashi Y, Sakakibara H, Kusano M, Shinozaki Y, Pulungan SI, Kubo Y, Nakano R, Ezura H.

Plant Cell Physiol. 2019 Jan 1;60(1):38-51. doi: 10.1093/pcp/pcy184.


Agrobacterium tumefaciens Enhances Biosynthesis of Two Distinct Auxins in the Formation of Crown Galls.

Mashiguchi K, Hisano H, Takeda-Kamiya N, Takebayashi Y, Ariizumi T, Gao Y, Ezura H, Sato K, Zhao Y, Hayashi KI, Kasahara H.

Plant Cell Physiol. 2019 Jan 1;60(1):29-37. doi: 10.1093/pcp/pcy182.


Prognostic impact of the tumor immune microenvironment in synovial sarcoma.

Oike N, Kawashima H, Ogose A, Hotta T, Hatano H, Ariizumi T, Sasaki T, Yamagishi T, Umezu H, Endo N.

Cancer Sci. 2018 Oct;109(10):3043-3054. doi: 10.1111/cas.13769. Epub 2018 Sep 16.


Identification and functional study of a mild allele of SlDELLA gene conferring the potential for improved yield in tomato.

Shinozaki Y, Ezura K, Hu J, Okabe Y, Bénard C, Prodhomme D, Gibon Y, Sun TP, Ezura H, Ariizumi T.

Sci Rep. 2018 Aug 13;8(1):12043. doi: 10.1038/s41598-018-30502-w.


Novel erythrocyte clumps revealed by an orphan gene Newtic1 in circulating blood and regenerating limbs of the adult newt.

Casco-Robles RM, Watanabe A, Eto K, Takeshima K, Obata S, Kinoshita T, Ariizumi T, Nakatani K, Nakada T, Tsonis PA, Casco-Robles MM, Sakurai K, Yahata K, Maruo F, Toyama F, Chiba C.

Sci Rep. 2018 May 10;8(1):7455. doi: 10.1038/s41598-018-25867-x.


JRE4 is a master transcriptional regulator of defense-related steroidal glycoalkaloids in tomato.

Nakayasu M, Shioya N, Shikata M, Thagun C, Abdelkareem A, Okabe Y, Ariizumi T, Arimura GI, Mizutani M, Ezura H, Hashimoto T, Shoji T.

Plant J. 2018 Jun;94(6):975-990. doi: 10.1111/tpj.13911. Epub 2018 Apr 29.


The Diagnostic and Prognostic Value of Hematological and Chemical Abnormalities in Soft Tissue Sarcoma: A Comparative Study in Patients with Benign and Malignant Soft Tissue Tumors.

Ariizumi T, Kawashima H, Ogose A, Sasaki T, Hotta T, Hatano H, Morita T, Endo N.

Ann Clin Lab Sci. 2018 Jan;48(1):11-17.


SlLAX1 is Required for Normal Leaf Development Mediated by Balanced Adaxial and Abaxial Pavement Cell Growth in Tomato.

Pulungan SI, Yano R, Okabe Y, Ichino T, Kojima M, Takebayashi Y, Sakakibara H, Ariizumi T, Ezura H.

Plant Cell Physiol. 2018 Jun 1;59(6):1170-1186. doi: 10.1093/pcp/pcy052.


Application and development of genome editing technologies to the Solanaceae plants.

Yamamoto T, Kashojiya S, Kamimura S, Kameyama T, Ariizumi T, Ezura H, Miura K.

Plant Physiol Biochem. 2018 Oct;131:37-46. doi: 10.1016/j.plaphy.2018.02.019. Epub 2018 Mar 2. Review.


Denosumab as a potential therapeutic option for leiomyosarcoma with osteoclast-like giant cells: A case report.

Sasaki T, Kawashima H, Ariizumi T, Yamagishi T, Oike N, Umezu H, Inagawa S, Hotta T, Endo N, Ogose A.

Mol Clin Oncol. 2018 Jan;8(1):30-33. doi: 10.3892/mco.2017.1489. Epub 2017 Nov 6.


Biology in the Dry Seed: Transcriptome Changes Associated with Dry Seed Dormancy and Dormancy Loss in the Arabidopsis GA-Insensitive sleepy1-2 Mutant.

Nelson SK, Ariizumi T, Steber CM.

Front Plant Sci. 2017 Dec 22;8:2158. doi: 10.3389/fpls.2017.02158. eCollection 2017.


In Vitro Induction of Xenopus Embryonic Organs Using Animal Cap Cells.

Ariizumi T, Michiue T, Asashima M.

Cold Spring Harb Protoc. 2017 Dec 1;2017(12):pdb.prot097410. doi: 10.1101/pdb.prot097410.


Genome-wide identification of pistil-specific genes expressed during fruit set initiation in tomato (Solanum lycopersicum).

Ezura K, Ji-Seong K, Mori K, Suzuki Y, Kuhara S, Ariizumi T, Ezura H.

PLoS One. 2017 Jul 6;12(7):e0180003. doi: 10.1371/journal.pone.0180003. eCollection 2017.


A malignant solitary fibrous tumour arising from the first lumbar vertebra and mimicking an osteosarcoma: a case report.

Oike N, Kawashima H, Ogose A, Hotta T, Hirano T, Ariizumi T, Yamagishi T, Umezu H, Inagawa S, Endo N.

World J Surg Oncol. 2017 May 11;15(1):100. doi: 10.1186/s12957-017-1161-0.


Frequent expression of human leukocyte antigen class I and the status of intratumoral immune cells in alveolar soft part sarcoma.

Ogose A, Kawashima H, Hotta T, Ariizumi T, Yamagishi T, Oike N, Sasaki T, Hatano H, Umezu H, Endo N.

Oncol Lett. 2017 Apr;13(4):2169-2176. doi: 10.3892/ol.2017.5696. Epub 2017 Feb 8.


Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion.

Shimatani Z, Kashojiya S, Takayama M, Terada R, Arazoe T, Ishii H, Teramura H, Yamamoto T, Komatsu H, Miura K, Ezura H, Nishida K, Ariizumi T, Kondo A.

Nat Biotechnol. 2017 May;35(5):441-443. doi: 10.1038/nbt.3833. Epub 2017 Mar 27.


SEXUAL STERILITY is Essential for Both Male and Female Gametogenesis in Tomato.

Hao S, Ariizumi T, Ezura H.

Plant Cell Physiol. 2017 Jan 1;58(1):22-34. doi: 10.1093/pcp/pcw214.


Extensor reconstruction of the knee using the fibular transposition technique after proximal tibial resection.

Kawashima H, Ogose A, Hotta T, Ariizumi T, Yamagishi T, Endo N.

Knee. 2017 Jun;24(3):657-662. doi: 10.1016/j.knee.2016.11.005. Epub 2016 Dec 1.


Chromosomal rearrangements in myoepithelial carcinoma of the breast that presented as metachronic double cancer with invasive ductal carcinoma in the ipsilateral breast.

Kawashima H, Ariizumi T, Saijo Y, Moriyama M, Umezu H, Ikeda Y, Ogose A, Endo N.

Cancer Genet. 2016 Nov;209(11):501-505. doi: 10.1016/j.cancergen.2016.10.005. Epub 2016 Oct 29.


Intravertebral cleft in pathological vertebral collapse resulting from cancer metastasis: report of three cases.

Hatano H, Oike N, Ariizumi T, Sasaki T, Kawashima H.

Skeletal Radiol. 2016 Dec;45(12):1747-1750. Epub 2016 Oct 6.


Involvement of vacuolar processing enzyme SlVPE5 in post-transcriptional process of invertase in sucrose accumulation in tomato.

Wang N, Duhita N, Ariizumi T, Ezura H.

Plant Physiol Biochem. 2016 Nov;108:71-78. doi: 10.1016/j.plaphy.2016.06.037. Epub 2016 Jun 29.


Activating glutamate decarboxylase activity by removing the autoinhibitory domain leads to hyper γ-aminobutyric acid (GABA) accumulation in tomato fruit.

Takayama M, Matsukura C, Ariizumi T, Ezura H.

Plant Cell Rep. 2017 Jan;36(1):103-116. doi: 10.1007/s00299-016-2061-4. Epub 2016 Oct 4.


Receptor-Activator of Nuclear KappaB Ligand Expression as a New Therapeutic Target in Primary Bone Tumors.

Yamagishi T, Kawashima H, Ogose A, Ariizumi T, Sasaki T, Hatano H, Hotta T, Endo N.

PLoS One. 2016 May 10;11(5):e0154680. doi: 10.1371/journal.pone.0154680. eCollection 2016.


The role of ethylene in the regulation of ovary senescence and fruit set in tomato (Solanum lycopersicum).

Shinozaki Y, Ezura H, Ariizumi T.

Plant Signal Behav. 2018 Apr 3;13(4):e1146844. doi: 10.1080/15592324.2016.1146844. Epub 2018 Apr 16.


TOMATOMA Update: Phenotypic and Metabolite Information in the Micro-Tom Mutant Resource.

Shikata M, Hoshikawa K, Ariizumi T, Fukuda N, Yamazaki Y, Ezura H.

Plant Cell Physiol. 2016 Jan;57(1):e11. doi: 10.1093/pcp/pcv194. Epub 2015 Dec 30.


Effect of temozolomide on the viability of musculoskeletal sarcoma cells.

Kusabe Y, Kawashima H, Ogose A, Sasaki T, Ariizumi T, Hotta T, Endo N.

Oncol Lett. 2015 Oct;10(4):2511-2518. Epub 2015 Jul 17.


Potential Use of a Weak Ethylene Receptor Mutant, Sletr1-2, as Breeding Material To Extend Fruit Shelf Life of Tomato.

Mubarok S, Okabe Y, Fukuda N, Ariizumi T, Ezura H.

J Agric Food Chem. 2015 Sep 16;63(36):7995-8007. doi: 10.1021/acs.jafc.5b02742. Epub 2015 Sep 1.


Tomato Glutamate Decarboxylase Genes SlGAD2 and SlGAD3 Play Key Roles in Regulating γ-Aminobutyric Acid Levels in Tomato (Solanum lycopersicum).

Takayama M, Koike S, Kusano M, Matsukura C, Saito K, Ariizumi T, Ezura H.

Plant Cell Physiol. 2015 Aug;56(8):1533-45. doi: 10.1093/pcp/pcv075. Epub 2015 May 25.


Ethylene suppresses tomato (Solanum lycopersicum) fruit set through modification of gibberellin metabolism.

Shinozaki Y, Hao S, Kojima M, Sakakibara H, Ozeki-Iida Y, Zheng Y, Fei Z, Zhong S, Giovannoni JJ, Rose JK, Okabe Y, Heta Y, Ezura H, Ariizumi T.

Plant J. 2015 Jul;83(2):237-51. doi: 10.1111/tpj.12882. Epub 2015 Jun 11.


Real-time polymerase chain reaction analysis of MDM2 and CDK4 expression using total RNA from core-needle biopsies is useful for diagnosing adipocytic tumors.

Sasaki T, Ogose A, Kawashima H, Hotta T, Hatano H, Ariizumi T, Umezu H, Ohashi R, Tohyama T, Tanabe N, Endo N.

BMC Cancer. 2014 Jun 26;14:468. doi: 10.1186/1471-2407-14-468.


Malignant transformation of fibrous dysplasia: A case report.

Hatano H, Morita T, Ariizumi T, Kawashima H, Ogose A.

Oncol Lett. 2014 Jul;8(1):384-386. Epub 2014 Apr 22.


Identification of the carotenoid modifying gene PALE YELLOW PETAL 1 as an essential factor in xanthophyll esterification and yellow flower pigmentation in tomato (Solanum lycopersicum).

Ariizumi T, Kishimoto S, Kakami R, Maoka T, Hirakawa H, Suzuki Y, Ozeki Y, Shirasawa K, Bernillon S, Okabe Y, Moing A, Asamizu E, Rothan C, Ohmiya A, Ezura H.

Plant J. 2014 Aug;79(3):453-65. doi: 10.1111/tpj.12570. Epub 2014 Jul 2.


The roles of the GA receptors GID1a, GID1b, and GID1c in sly1-independent GA signaling.

Hauvermale AL, Ariizumi T, Steber CM.

Plant Signal Behav. 2014;9(2):e28030. Epub 2014 Feb 12.


A novel tomato mutant, Solanum lycopersicum elongated fruit1 (Slelf1), exhibits an elongated fruit shape caused by increased cell layers in the proximal region of the ovary.

Chusreeaeom K, Ariizumi T, Asamizu E, Okabe Y, Shirasawa K, Ezura H.

Mol Genet Genomics. 2014 Jun;289(3):399-409. doi: 10.1007/s00438-014-0822-8. Epub 2014 Feb 12.


Inhibition of CUTIN DEFICIENT 2 Causes Defects in Cuticle Function and Structure and Metabolite Changes in Tomato Fruit.

Kimbara J, Yoshida M, Ito H, Kitagawa M, Takada W, Hayashi K, Shibutani Y, Kusano M, Okazaki Y, Nakabayashi R, Mori T, Saito K, Ariizumi T, Ezura H.

Plant Cell Physiol. 2013 Sep;54(9):1535-48. doi: 10.1093/pcp/pct100. Epub 2013 Aug 2.


Lifting della repression of Arabidopsis seed germination by nonproteolytic gibberellin signaling.

Ariizumi T, Hauvermale AL, Nelson SK, Hanada A, Yamaguchi S, Steber CM.

Plant Physiol. 2013 Aug;162(4):2125-39. doi: 10.1104/pp.113.219451. Epub 2013 Jul 1.


Telomelysin shows potent antitumor activity through apoptotic and non-apoptotic cell death in soft tissue sarcoma cells.

Li GD, Kawashima H, Ogose A, Ariizumi T, Hotta T, Kuwano R, Urata Y, Fujiwara T, Endo N.

Cancer Sci. 2013 Sep;104(9):1178-88. doi: 10.1111/cas.12208. Epub 2013 Jun 28.


Updating the Micro-Tom TILLING platform.

Okabe Y, Ariizumi T, Ezura H.

Breed Sci. 2013 Mar;63(1):42-8. doi: 10.1270/jsbbs.63.42. Epub 2013 Mar 1.


Genes that influence yield in tomato.

Ariizumi T, Shinozaki Y, Ezura H.

Breed Sci. 2013 Mar;63(1):3-13. doi: 10.1270/jsbbs.63.3. Epub 2013 Mar 1.


Mapping of Micro-Tom BAC-End Sequences to the Reference Tomato Genome Reveals Possible Genome Rearrangements and Polymorphisms.

Asamizu E, Shirasawa K, Hirakawa H, Sato S, Tabata S, Yano K, Ariizumi T, Shibata D, Ezura H.

Int J Plant Genomics. 2012;2012:437026. doi: 10.1155/2012/437026. Epub 2012 Nov 27.


Availability of Micro-Tom mutant library combined with TILLING in molecular breeding of tomato fruit shelf-life.

Okabe Y, Asamizu E, Ariizumi T, Shirasawa K, Tabata S, Ezura H.

Breed Sci. 2012 Jun;62(2):202-8. doi: 10.1270/jsbbs.62.202. Epub 2012 Jun 19.


Long-term efficacy of oral alendronate therapy in an elderly patient with polyostotic fibrous dysplasia: A case report.

Li GD, Ogose A, Hotta T, Kawashima H, Ariizumi T, Xu Y, Endo N.

Oncol Lett. 2011 Nov;2(6):1239-1242. Epub 2011 Aug 2.


Gibberellin signaling: a theme and variations on DELLA repression.

Hauvermale AL, Ariizumi T, Steber CM.

Plant Physiol. 2012 Sep;160(1):83-92. doi: 10.1104/pp.112.200956. Epub 2012 Jul 27. Review. No abstract available.


A novel class of sticky peel and light green mutations causes cuticle deficiency in leaves and fruits of tomato (Solanum lycopersicum).

Kimbara J, Yoshida M, Ito H, Hosoi K, Kusano M, Kobayashi M, Ariizumi T, Asamizu E, Ezura H.

Planta. 2012 Nov;236(5):1559-70. doi: 10.1007/s00425-012-1719-6. Epub 2012 Jul 27.


Tomato TILLING technology: development of a reverse genetics tool for the efficient isolation of mutants from Micro-Tom mutant libraries.

Okabe Y, Asamizu E, Saito T, Matsukura C, Ariizumi T, Brès C, Rothan C, Mizoguchi T, Ezura H.

Plant Cell Physiol. 2011 Nov;52(11):1994-2005. doi: 10.1093/pcp/pcr134. Epub 2011 Sep 30.

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