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Items: 7


DNA Methylation Changes in Regional Lung Macrophages Are Associated with Metabolic Differences.

Armstrong DA, Chen Y, Dessaint JA, Aridgides DS, Channon JY, Mellinger DL, Christensen BC, Ashare A.

Immunohorizons. 2019 Jul 2;3(7):274-281. doi: 10.4049/immunohorizons.1900042.


Functional and metabolic impairment in cigarette smoke-exposed macrophages is tied to oxidative stress.

Aridgides DS, Mellinger DL, Armstrong DA, Hazlett HF, Dessaint JA, Hampton TH, Atkins GT, Carroll JL, Ashare A.

Sci Rep. 2019 Jul 3;9(1):9624. doi: 10.1038/s41598-019-46045-7.


Genome-wide DNA methylation profiling shows a distinct epigenetic signature associated with lung macrophages in cystic fibrosis.

Chen Y, Armstrong DA, Salas LA, Hazlett HF, Nymon AB, Dessaint JA, Aridgides DS, Mellinger DL, Liu X, Christensen BC, Ashare A.

Clin Epigenetics. 2018 Dec 10;10(1):152. doi: 10.1186/s13148-018-0580-2.


Trypanosoma cruzi Neurotrophic Factor Facilitates Cardiac Repair in a Mouse Model of Chronic Chagas Disease.

Ledoux T, Aridgides D, Salvador R, Ngwenyama N, Panagiotidou S, Alcaide P, Blanton RM, Perrin MA.

J Pharmacol Exp Ther. 2019 Jan;368(1):11-20. doi: 10.1124/jpet.118.251900. Epub 2018 Oct 22.


Parasite-derived neurotrophic factor/trans-sialidase of Trypanosoma cruzi links neurotrophic signaling to cardiac innate immune response.

Salvador R, Aridgides D, PereiraPerrin M.

Infect Immun. 2014 Sep;82(9):3687-96. doi: 10.1128/IAI.02098-14. Epub 2014 Jun 16.


Trypanosoma cruzi coaxes cardiac fibroblasts into preventing cardiomyocyte death by activating nerve growth factor receptor TrkA.

Aridgides D, Salvador R, PereiraPerrin M.

PLoS One. 2013;8(2):e57450. doi: 10.1371/journal.pone.0057450. Epub 2013 Feb 21.


Trypanosoma cruzi highjacks TrkC to enter cardiomyocytes and cardiac fibroblasts while exploiting TrkA for cardioprotection against oxidative stress.

Aridgides D, Salvador R, PereiraPerrin M.

Cell Microbiol. 2013 Aug;15(8):1357-66. doi: 10.1111/cmi.12119. Epub 2013 Mar 14.

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