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Items: 1 to 50 of 92

1.

Nicotine smoking concentrations modulate GABAergic synaptic transmission in murine medial prefrontal cortex by activation of α7* and β2* nicotinic receptors.

Cuevas-Olguin R, Esquivel-Rendon E, Vargas-Mireles J, Barajas-Lόpez C, Salgado-Delgado R, Saderi N, Arias HR, Atzori M, Miranda-Morales M.

Eur J Neurosci. 2019 Oct 15. doi: 10.1111/ejn.14595. [Epub ahead of print]

PMID:
31613395
2.

Selectivity of (±)-citalopram at nicotinic acetylcholine receptors and different inhibitory mechanisms between habenular α3β4* and α9α10 subtypes.

Arias HR, Jin XT, Gallino S, Peng C, Feuerbach D, García-Colunga J, Elgoyhen AB, Drenan RM, Ortells MO.

Neurochem Int. 2019 Dec;131:104552. doi: 10.1016/j.neuint.2019.104552. Epub 2019 Sep 20.

PMID:
31545995
3.

Alkaloids Purified from Aristotelia chilensis Inhibit the Human α3β4 Nicotinic Acetylcholine Receptor with Higher Potencies Compared with the Human α4β2 and α7 Subtypes.

Arias HR, Ortells MO, Feuerbach D, Burgos V, Paz C.

J Nat Prod. 2019 Jul 26;82(7):1953-1960. doi: 10.1021/acs.jnatprod.9b00314. Epub 2019 Jul 5.

PMID:
31276409
4.

3-Furan-2-yl-N-p-tolyl-acrylamide, a highly selective positive allosteric modulator of α7 nicotinic receptors, produces anxiolytic-like activity in mice.

Targowska-Duda KM, Budzynska B, Michalak A, Jozwiak K, Biala G, Arias HR.

J Psychopharmacol. 2019 May;33(5):558-567. doi: 10.1177/0269881118821100. Epub 2019 Jan 15.

PMID:
30644335
5.

Tricyclic antidepressants inhibit hippocampal α7* and α9α10 nicotinic acetylcholine receptors by different mechanisms.

Arias HR, Vázquez-Gómez E, Hernández-Abrego A, Gallino S, Feuerbach D, Ortells MO, Elgoyhen AB, García-Colunga J.

Int J Biochem Cell Biol. 2018 Jul;100:1-10. doi: 10.1016/j.biocel.2018.04.017. Epub 2018 Apr 25.

PMID:
29704625
6.

Positive allosteric modulators of α7* or β2* nicotinic acetylcholine receptors trigger different kinase pathways in mitochondria.

Uspenska K, Lykhmus O, Arias HR, Pons S, Maskos U, Komisarenko S, Skok M.

Int J Biochem Cell Biol. 2018 Jun;99:226-235. doi: 10.1016/j.biocel.2018.04.018. Epub 2018 Apr 25.

PMID:
29704624
7.

Drimane Sesquiterpenoids Noncompetitively Inhibit Human α4β2 Nicotinic Acetylcholine Receptors with Higher Potency Compared to Human α3β4 and α7 Subtypes.

Arias HR, Feuerbach D, Schmidt B, Heydenreich M, Paz C, Ortells MO.

J Nat Prod. 2018 Apr 27;81(4):811-817. doi: 10.1021/acs.jnatprod.7b00893. Epub 2018 Apr 10.

PMID:
29634269
8.

Molecular interactions of type I and type II positive allosteric modulators with the human α7 nicotinic acetylcholine receptor: an in silico study.

Targowska-Duda KM, Kaczor AA, Jozwiak K, Arias HR.

J Biomol Struct Dyn. 2019 Feb;37(2):411-439. doi: 10.1080/07391102.2018.1427634. Epub 2018 Feb 16.

PMID:
29363414
9.

Coronaridine congeners modulate mitochondrial α3β4* nicotinic acetylcholine receptors with different potency and through distinct intra-mitochondrial pathways.

Arias HR, Lykhmus O, Uspenska K, Skok M.

Neurochem Int. 2018 Mar;114:26-32. doi: 10.1016/j.neuint.2017.12.008. Epub 2017 Dec 23.

PMID:
29277577
10.

Selectivity of coronaridine congeners at nicotinic acetylcholine receptors and inhibitory activity on mouse medial habenula.

Arias HR, Jin X, Feuerbach D, Drenan RM.

Int J Biochem Cell Biol. 2017 Nov;92:202-209. doi: 10.1016/j.biocel.2017.10.006. Epub 2017 Oct 16.

11.

Nicotine facilitates nicotinic acetylcholine receptor targeting to mitochondria but makes them less susceptible to selective ligands.

Uspenska K, Lykhmus O, Gergalova G, Chernyshov V, Arias HR, Komisarenko S, Skok M.

Neurosci Lett. 2017 Aug 24;656:43-50. doi: 10.1016/j.neulet.2017.07.009. Epub 2017 Jul 9.

PMID:
28700952
12.

Significance of the nicotinic alpha7 receptor in cognition and antipsychotic-like behavior in the rat.

Wadenberg MG, Manetti D, Romanelli MN, Arias HR.

Behav Brain Res. 2017 Aug 30;333:129-134. doi: 10.1016/j.bbr.2017.07.001. Epub 2017 Jul 3.

PMID:
28684359
13.

3-Furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the α7 nicotinic receptor, reverses schizophrenia-like cognitive and social deficits in rats.

Potasiewicz A, Hołuj M, Kos T, Popik P, Arias HR, Nikiforuk A.

Neuropharmacology. 2017 Feb;113(Pt A):188-197. doi: 10.1016/j.neuropharm.2016.10.002. Epub 2016 Oct 4.

PMID:
27717880
14.

Bupropion and its photoreactive analog (±)-SADU-3-72 interact with luminal and non-luminal sites at human α4β2 nicotinic acetylcholine receptors.

Arias HR, Feuerbach D, Ortells MO.

Neurochem Int. 2016 Nov;100:67-77. doi: 10.1016/j.neuint.2016.08.013. Epub 2016 Sep 6.

PMID:
27612850
15.

Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content.

Arias HR, Ravazzini F, Targowska-Duda KM, Kaczor AA, Feuerbach D, Boffi JC, Draczkowski P, Montag D, Brown BM, Elgoyhen AB, Jozwiak K, Puia G.

Int J Biochem Cell Biol. 2016 Jul;76:19-30. doi: 10.1016/j.biocel.2016.04.015. Epub 2016 Apr 26.

PMID:
27129924
16.

Exploring the positive allosteric modulation of human α7 nicotinic receptors from a single-channel perspective.

Andersen ND, Nielsen BE, Corradi J, Tolosa MF, Feuerbach D, Arias HR, Bouzat C.

Neuropharmacology. 2016 Aug;107:189-200. doi: 10.1016/j.neuropharm.2016.02.032. Epub 2016 Feb 27.

PMID:
26926428
17.

Role of Nicotinic and Muscarinic Receptors on Synaptic Plasticity and Neurological Diseases.

Fuenzalida M, Pérez MÁ, Arias HR.

Curr Pharm Des. 2016;22(14):2004-14. Review.

PMID:
26818867
18.

The positive allosteric modulator of α7 nicotinic acetylcholine receptors, 3-furan-2-yl-N-p-tolyl-acrylamide, enhances memory processes and stimulates ERK1/2 phosphorylation in mice.

Targowska-Duda KM, Wnorowski A, Budzynska B, Jozwiak K, Biala G, Arias HR.

Behav Brain Res. 2016 Apr 1;302:142-51. doi: 10.1016/j.bbr.2016.01.002. Epub 2016 Jan 8.

PMID:
26778787
19.

The Antinociceptive and Antiinflammatory Properties of 3-furan-2-yl-N-p-tolyl-acrylamide, a Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptors in Mice.

Bagdas D, Targowska-Duda KM, López JJ, Perez EG, Arias HR, Damaj MI.

Anesth Analg. 2015 Nov;121(5):1369-77. doi: 10.1213/ANE.0000000000000902.

20.

Pro-cognitive activity in rats of 3-furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the α7 nicotinic acetylcholine receptor.

Potasiewicz A, Kos T, Ravazzini F, Puia G, Arias HR, Popik P, Nikiforuk A.

Br J Pharmacol. 2015 Nov;172(21):5123-35. doi: 10.1111/bph.13277. Epub 2015 Oct 10. Erratum in: Br J Pharmacol. 2016 Jan;173(2):411.

21.

Similarities between the Binding Sites of SB-206553 at Serotonin Type 2 and Alpha7 Acetylcholine Nicotinic Receptors: Rationale for Its Polypharmacological Profile.

Möller-Acuña P, Contreras-Riquelme JS, Rojas-Fuentes C, Nuñez-Vivanco G, Alzate-Morales J, Iturriaga-Vásquez P, Arias HR, Reyes-Parada M.

PLoS One. 2015 Aug 5;10(8):e0134444. doi: 10.1371/journal.pone.0134444. eCollection 2015.

22.

The antidepressant-like activity of nicotine, but not of 3-furan-2-yl-N-p-tolyl-acrylamide, is regulated by the nicotinic receptor β4 subunit.

Arias HR, Targowska-Duda KM, Feuerbach D, Jozwiak K.

Neurochem Int. 2015 Aug;87:110-6. doi: 10.1016/j.neuint.2015.06.006. Epub 2015 Jun 23.

PMID:
26116439
23.

Coronaridine congeners inhibit human α3β4 nicotinic acetylcholine receptors by interacting with luminal and non-luminal sites.

Arias HR, Targowska-Duda KM, Feuerbach D, Jozwiak K.

Int J Biochem Cell Biol. 2015 Aug;65:81-90. doi: 10.1016/j.biocel.2015.05.015. Epub 2015 May 27.

PMID:
26022277
24.

Functional and structural interaction of (-)-lobeline with human α4β2 and α4β4 nicotinic acetylcholine receptor subtypes.

Arias HR, Feuerbach D, Ortells M.

Int J Biochem Cell Biol. 2015 Jul;64:15-24. doi: 10.1016/j.biocel.2015.03.003. Epub 2015 Mar 18.

PMID:
25794424
25.

Pharmacological and molecular studies on the interaction of varenicline with different nicotinic acetylcholine receptor subtypes. Potential mechanism underlying partial agonism at human α4β2 and α3β4 subtypes.

Arias HR, Feuerbach D, Targowska-Duda K, Kaczor AA, Poso A, Jozwiak K.

Biochim Biophys Acta. 2015 Feb;1848(2):731-41. doi: 10.1016/j.bbamem.2014.11.003. Epub 2014 Dec 2.

26.

Bupropion-induced inhibition of α7 nicotinic acetylcholine receptors expressed in heterologous cells and neurons from dorsal raphe nucleus and hippocampus.

Vázquez-Gómez E, Arias HR, Feuerbach D, Miranda-Morales M, Mihailescu S, Targowska-Duda KM, Jozwiak K, García-Colunga J.

Eur J Pharmacol. 2014 Oct 5;740:103-11. doi: 10.1016/j.ejphar.2014.06.059. Epub 2014 Jul 9.

PMID:
25016090
27.

Antidepressant activity in mice elicited by 3-furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the α7 nicotinic acetylcholine receptor.

Targowska-Duda KM, Feuerbach D, Biala G, Jozwiak K, Arias HR.

Neurosci Lett. 2014 May 21;569:126-30. doi: 10.1016/j.neulet.2014.03.067. Epub 2014 Apr 5.

PMID:
24708923
28.

Molecular interactions between mecamylamine enantiomers and the transmembrane domain of the human α4β2 nicotinic receptor.

Bondarenko V, Targowska-Duda KM, Jozwiak K, Tang P, Arias HR.

Biochemistry. 2014 Feb 11;53(5):908-18. doi: 10.1021/bi400969x. Epub 2014 Jan 30.

29.

Differential pharmacological activity of JN403 between α7 and muscle nicotinic acetylcholine receptors.

Arias HR, De Rosa MJ, Bergé I, Feuerbach D, Bouzat C.

Biochemistry. 2013 Nov 26;52(47):8480-8. doi: 10.1021/bi4012572. Epub 2013 Nov 11.

PMID:
24164482
30.

Role of the nicotinic receptor β4 subunit in the antidepressant activity of novel N,6-dimethyltricyclo[5.2.1.0²,⁶]decan-2-amine enantiomers.

Targowska-Duda KM, Jozwiak K, Arias HR.

Neurosci Lett. 2013 Oct 11;553:186-90. doi: 10.1016/j.neulet.2013.08.036. Epub 2013 Aug 27.

PMID:
23994392
31.

The β4 nicotinic receptor subunit modulates the chronic antidepressant effect mediated by bupropion.

Radhakrishnan R, Santamaría A, Escobar L, Arias HR.

Neurosci Lett. 2013 Oct 25;555:68-72. doi: 10.1016/j.neulet.2013.08.009. Epub 2013 Aug 24.

PMID:
23981664
32.

Novel 2-(substituted benzyl)quinuclidines inhibit human α7 and α4β2 nicotinic receptors by different mechanisms.

Arias HR, López JJ, Feuerbach D, Fierro A, Ortells MO, Pérez EG.

Int J Biochem Cell Biol. 2013 Nov;45(11):2420-30. doi: 10.1016/j.biocel.2013.08.003. Epub 2013 Aug 14.

PMID:
23954208
33.

(-)-Reboxetine inhibits muscle nicotinic acetylcholine receptors by interacting with luminal and non-luminal sites.

Arias HR, Ortells MO, Feuerbach D.

Neurochem Int. 2013 Nov;63(5):423-31. doi: 10.1016/j.neuint.2013.07.009. Epub 2013 Jul 31.

PMID:
23917086
34.

Structural and functional interaction of (±)-2-(N-tert-butylamino)-3'-iodo-4'-azidopropiophenone, a photoreactive bupropion derivative, with nicotinic acetylcholine receptors.

Arias HR, Feuerbach D, Targowska-Duda KM, Aggarwal S, Lapinsky DJ, Jozwiak K.

Neurochem Int. 2012 Dec;61(8):1433-41. doi: 10.1016/j.neuint.2012.10.011. Epub 2012 Oct 26. Erratum in: Neurochem Int. 2013 Nov;63(5):533.

PMID:
23103524
35.

Functional and structural interaction of (-)-reboxetine with the human α4β2 nicotinic acetylcholine receptor.

Arias HR, Fedorov NB, Benson LC, Lippiello PM, Gatto GJ, Feuerbach D, Ortells MO.

J Pharmacol Exp Ther. 2013 Jan;344(1):113-23. doi: 10.1124/jpet.112.197905. Epub 2012 Sep 25.

PMID:
23010362
36.

Structure-activity relationship of ibogaine analogs interacting with nicotinic acetylcholine receptors in different conformational states.

Arias HR, Feuerbach D, Targowska-Duda KM, Jozwiak K.

Int J Biochem Cell Biol. 2011 Sep;43(9):1330-9. doi: 10.1016/j.biocel.2011.05.011. Epub 2011 May 27.

PMID:
21642011
37.

Novel positive allosteric modulators of the human α7 nicotinic acetylcholine receptor.

Arias HR, Gu RX, Feuerbach D, Guo BB, Ye Y, Wei DQ.

Biochemistry. 2011 Jun 14;50(23):5263-78. doi: 10.1021/bi102001m. Epub 2011 May 17.

PMID:
21510634
38.

Positive and negative modulation of nicotinic receptors.

Arias HR.

Adv Protein Chem Struct Biol. 2010;80:153-203. doi: 10.1016/B978-0-12-381264-3.00005-9. Review.

PMID:
21109220
39.

Neuronal networks of nicotine addiction.

Ortells MO, Arias HR.

Int J Biochem Cell Biol. 2010 Dec;42(12):1931-5. doi: 10.1016/j.biocel.2010.08.019. Epub 2010 Sep 15. Review.

PMID:
20833261
40.

Interaction of ibogaine with human alpha3beta4-nicotinic acetylcholine receptors in different conformational states.

Arias HR, Rosenberg A, Targowska-Duda KM, Feuerbach D, Yuan XJ, Jozwiak K, Moaddel R, Wainer IW.

Int J Biochem Cell Biol. 2010 Sep;42(9):1525-35.

41.

Interaction of selective serotonin reuptake inhibitors with neuronal nicotinic acetylcholine receptors.

Arias HR, Feuerbach D, Targowska-Duda KM, Russell M, Jozwiak K.

Biochemistry. 2010 Jul 13;49(27):5734-42. doi: 10.1021/bi100536t. Erratum in: Biochemistry. 2010 Aug 17;49(32):6970.

PMID:
20527991
42.

Catharanthine alkaloids are noncompetitive antagonists of muscle-type nicotinic acetylcholine receptors.

Arias HR, Feuerbach D, Targowska-Duda KM, Jozwiak K.

Neurochem Int. 2010 Sep;57(2):153-61. doi: 10.1016/j.neuint.2010.05.007. Epub 2010 May 20.

PMID:
20493225
43.

Different interaction between the agonist JN403 and the competitive antagonist methyllycaconitine with the human alpha7 nicotinic acetylcholine receptor.

Arias HR, Gu RX, Feuerbach D, Wei DQ.

Biochemistry. 2010 May 18;49(19):4169-80. doi: 10.1021/bi901999v.

PMID:
20377277
44.

Neurochemical and behavioral effects elicited by bupropion and diethylpropion in rats.

Santamaría A, Arias HR.

Behav Brain Res. 2010 Jul 29;211(1):132-9. doi: 10.1016/j.bbr.2010.03.023. Epub 2010 Mar 20.

PMID:
20307582
45.

Interaction of 18-methoxycoronaridine with nicotinic acetylcholine receptors in different conformational states.

Arias HR, Rosenberg A, Feuerbach D, Targowska-Duda KM, Maciejewski R, Jozwiak K, Moaddel R, Glick SD, Wainer IW.

Biochim Biophys Acta. 2010 Jun;1798(6):1153-63. doi: 10.1016/j.bbamem.2010.03.013. Epub 2010 Mar 19.

46.

Tricyclic antidepressants and mecamylamine bind to different sites in the human alpha4beta2 nicotinic receptor ion channel.

Arias HR, Rosenberg A, Targowska-Duda KM, Feuerbach D, Jozwiak K, Moaddel R, Wainer IW.

Int J Biochem Cell Biol. 2010 Jun;42(6):1007-18. doi: 10.1016/j.biocel.2010.03.002. Epub 2010 Mar 17.

47.

Different interaction between tricyclic antidepressants and mecamylamine with the human alpha3beta4 nicotinic acetylcholine receptor ion channel.

Arias HR, Targowska-Duda KM, Feuerbach D, Sullivan CJ, Maciejewski R, Jozwiak K.

Neurochem Int. 2010 Mar;56(4):642-9. doi: 10.1016/j.neuint.2010.01.011. Epub 2010 Feb 1.

PMID:
20117161
48.

Inhibitory mechanisms and binding site location for serotonin selective reuptake inhibitors on nicotinic acetylcholine receptors.

Arias HR, Feuerbach D, Bhumireddy P, Ortells MO.

Int J Biochem Cell Biol. 2010 May;42(5):712-24. doi: 10.1016/j.biocel.2010.01.007. Epub 2010 Jan 14.

PMID:
20079457
49.
50.

Pharmacological and neurotoxicological actions mediated by bupropion and diethylpropion.

Arias HR, Santamaría A, Ali SF.

Int Rev Neurobiol. 2009;88:223-55. doi: 10.1016/S0074-7742(09)88009-4. Review.

PMID:
19897080

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