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Items: 18


TRIM8 is required for virus-induced IFN response in human plasmacytoid dendritic cells.

Maarifi G, Smith N, Maillet S, Moncorgé O, Chamontin C, Edouard J, Sohm F, Blanchet FP, Herbeuval JP, Lutfalla G, Levraud JP, Arhel NJ, Nisole S.

Sci Adv. 2019 Nov 20;5(11):eaax3511. doi: 10.1126/sciadv.aax3511. eCollection 2019 Nov.


Transportin-1 binds to the HIV-1 capsid via a nuclear localization signal and triggers uncoating.

Fernandez J, Machado AK, Lyonnais S, Chamontin C, Gärtner K, Léger T, Henriquet C, Garcia C, Portilho DM, Pugnière M, Chaloin L, Muriaux D, Yamauchi Y, Blaise M, Nisole S, Arhel NJ.

Nat Microbiol. 2019 Nov;4(11):1840-1850. doi: 10.1038/s41564-019-0575-6. Epub 2019 Oct 14.


[SUMO regulates the capacity of TRIM5α to inhibit HIV-1].

Nisole S, Fernandez J, Maarifi G, Arhel NJ.

Med Sci (Paris). 2019 Feb;35(2):106-109. doi: 10.1051/medsci/2019016. Epub 2019 Feb 18. French. No abstract available.


RanBP2 regulates the anti-retroviral activity of TRIM5α by SUMOylation at a predicted phosphorylated SUMOylation motif.

Maarifi G, Fernandez J, Portilho DM, Boulay A, Dutrieux J, Oddos S, Butler-Browne G, Nisole S, Arhel NJ.

Commun Biol. 2018 Nov 15;1:193. doi: 10.1038/s42003-018-0198-0. eCollection 2018.


Endogenous TRIM5α Function Is Regulated by SUMOylation and Nuclear Sequestration for Efficient Innate Sensing in Dendritic Cells.

Portilho DM, Fernandez J, Ringeard M, Machado AK, Boulay A, Mayer M, Müller-Trutwin M, Beignon AS, Kirchhoff F, Nisole S, Arhel NJ.

Cell Rep. 2016 Jan 12;14(2):355-69. doi: 10.1016/j.celrep.2015.12.039. Epub 2015 Dec 31.


PML/TRIM19-Dependent Inhibition of Retroviral Reverse-Transcription by Daxx.

Dutrieux J, Maarifi G, Portilho DM, Arhel NJ, Chelbi-Alix MK, Nisole S.

PLoS Pathog. 2015 Nov 13;11(11):e1005280. doi: 10.1371/journal.ppat.1005280. eCollection 2015 Nov.


TRIM5α is a SUMO substrate.

Dutrieux J, Portilho DM, Arhel NJ, Hazan U, Nisole S.

Retrovirology. 2015 Mar 24;12:28. doi: 10.1186/s12977-015-0155-7.


Microtubule-associated proteins 1 (MAP1) promote human immunodeficiency virus type I (HIV-1) intracytoplasmic routing to the nucleus.

Fernandez J, Portilho DM, Danckaert A, Munier S, Becker A, Roux P, Zambo A, Shorte S, Jacob Y, Vidalain PO, Charneau P, Clavel F, Arhel NJ.

J Biol Chem. 2015 Feb 20;290(8):4631-46. doi: 10.1074/jbc.M114.613133. Epub 2014 Dec 11.


Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration.

Di Nunzio F, Danckaert A, Fricke T, Perez P, Fernandez J, Perret E, Roux P, Shorte S, Charneau P, Diaz-Griffero F, Arhel NJ.

PLoS One. 2012;7(9):e46037. doi: 10.1371/journal.pone.0046037. Epub 2012 Sep 25. Erratum in: PLoS One. 2013;8(12). doi:10.1371/annotation/34f46796-5d53-4a23-b3df-b599b0369eb9.


HIV-derived vectors for therapy and vaccination against HIV.

Di Nunzio F, Félix T, Arhel NJ, Nisole S, Charneau P, Beignon AS.

Vaccine. 2012 Mar 28;30(15):2499-509. doi: 10.1016/j.vaccine.2012.01.089. Epub 2012 Feb 13. Review.


Implications of Nef: host cell interactions in viral persistence and progression to AIDS.

Arhel NJ, Kirchhoff F.

Curr Top Microbiol Immunol. 2009;339:147-75. doi: 10.1007/978-3-642-02175-6_8. Review.


Bisarsenical labeling of HIV-1 for real-time fluorescence microscopy.

Arhel NJ, Charneau P.

Methods Mol Biol. 2009;485:151-9. doi: 10.1007/978-1-59745-170-3_11.


Lack of endogenous TRIM5alpha-mediated restriction in rhesus macaque dendritic cells.

Arhel NJ, Nisole S, Carthagena L, Coutant F, Souque P, Brussel A, Estaquier J, Charneau P.

Blood. 2008 Nov 1;112(9):3772-6. doi: 10.1182/blood-2008-04-151761. Epub 2008 Aug 14.


HIV-1 DNA Flap formation promotes uncoating of the pre-integration complex at the nuclear pore.

Arhel NJ, Souquere-Besse S, Munier S, Souque P, Guadagnini S, Rutherford S, Prévost MC, Allen TD, Charneau P.

EMBO J. 2007 Jun 20;26(12):3025-37. Epub 2007 Jun 7.


The role of the retinoblastoma protein (Rb) in the nuclear localization of BAG-1: implications for colorectal tumour cell survival.

Clemo NK, Arhel NJ, Barnes JD, Baker J, Moorghen M, Packham GK, Paraskeva C, Williams AC.

Biochem Soc Trans. 2005 Aug;33(Pt 4):676-8. Review.


Nuclear BAG-1 expression inhibits apoptosis in colorectal adenoma-derived epithelial cells.

Barnes JD, Arhel NJ, Lee SS, Sharp A, Al-Okail M, Packham G, Hague A, Paraskeva C, Williams AC.

Apoptosis. 2005 Mar;10(2):301-11.


The retinoblastoma protein interacts with Bag-1 in human colonic adenoma and carcinoma derived cell lines.

Arhel NJ, Packham G, Townsend PA, Collard TJ, H-Zadeh AM, Sharp A, Cutress RI, Malik K, Hague A, Paraskeva C, Williams AC.

Int J Cancer. 2003 Sep 1;106(3):364-71.

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