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A novel approach to childhood obesity: circulating chemokines and growth factors as biomarkers of insulin resistance.

Rivera P, Martos-Moreno GÁ, Barrios V, Suárez J, Pavón FJ, Chowen JA, Rodríguez de Fonseca F, Argente J.

Pediatr Obes. 2018 Oct 22. doi: 10.1111/ijpo.12473. [Epub ahead of print]


Neurobiological characteristics underlying metabolic differences between males and females.

Chowen JA, Freire-Regatillo A, Argente J.

Prog Neurobiol. 2018 Sep 5. pii: S0301-0082(18)30083-2. doi: 10.1016/j.pneurobio.2018.09.001. [Epub ahead of print] Review.


Metabolomics changes in patients with PAPP-A2 deficiency in response to rhIGF1 treatment.

Mastrangelo A, Martos-Moreno GÁ, Rupérez FJ, Chowen JA, Barbas C, Argente J.

Growth Horm IGF Res. 2018 Aug 12;42-43:28-31. doi: 10.1016/j.ghir.2018.08.002. [Epub ahead of print]


Genetic causes of proportionate short stature.

Argente J, Pérez-Jurado LA.

Best Pract Res Clin Endocrinol Metab. 2018 Aug;32(4):499-522. doi: 10.1016/j.beem.2018.05.012. Epub 2018 Jun 6. Review.


[Parental obesity is associated with the severity of childhood obesity and its comorbidities].

Martínez-Villanueva J, González-Leal R, Argente J, Martos-Moreno GÁ.

An Pediatr (Barc). 2018 Jul 24. pii: S1695-4033(18)30301-1. doi: 10.1016/j.anpedi.2018.06.013. [Epub ahead of print] Spanish.


[Influence of neonatal anthropometry on the comorbidities of the obese patient].

González-Leal R, Martínez-Villanueva J, Argente J, Martos-Moreno GÁ.

An Pediatr (Barc). 2018 Jul 2. pii: S1695-4033(18)30227-3. doi: 10.1016/j.anpedi.2018.05.017. [Epub ahead of print] Spanish.


Clinical management of childhood hyperthyroidism with and without Down syndrome: a longitudinal study at a single center.

Dos Santos TJ, Martos-Moreno GÁ, Muñoz-Calvo MT, Pozo J, Rodríguez-Artalejo F, Argente J.

J Pediatr Endocrinol Metab. 2018 Jul 26;31(7):743-750. doi: 10.1515/jpem-2018-0132.


[Thickening of the pituitary stalk in children and adolescents with central diabetes insipidus: Causes and consequences].

Corredor Andrés B, Muñoz Calvo MT, López Pino MÁ, Márquez Rivera M, Travieso Suárez L, Pozo Román J, Argente J.

An Pediatr (Barc). 2018 Jun 9. pii: S1695-4033(18)30182-6. doi: 10.1016/j.anpedi.2018.05.002. [Epub ahead of print] Spanish.


Frequent and Rare HABP2 Variants Are Not Associated with Increased Susceptibility to Familial Nonmedullary Thyroid Carcinoma in the Spanish Population.

de Randamie R, Martos-Moreno GÁ, Lumbreras C, Chueca M, Donnay S, Luque M, Regojo RM, Mendiola M, Hardisson D, Argente J, Moreno JC.

Horm Res Paediatr. 2018;89(6):397-407. doi: 10.1159/000487395. Epub 2018 Jun 12.


Response to growth hormone in patients with RNPC3 mutations.

Martos-Moreno GÁ, Travieso-Suárez L, Pozo-Román J, Muñoz-Calvo MT, Chowen JA, Frilander MJ, Pérez-Jurado LA, Hawkins FG, Argente J.

EMBO Mol Med. 2018 Jul;10(7). pii: e9143. doi: 10.15252/emmm.201809143. No abstract available.


[Giant breast fibroadenomas in adolescents: Diagnostic and therapeutic procedures].

Corredor Andrés B, Márquez Rivera M, Lobo Bailón F, González Meli B, Azorín Cuadrillero D, Muñoz Calvo MT, Argente J.

An Pediatr (Barc). 2018 May 22. pii: S1695-4033(18)30017-1. doi: 10.1016/j.anpedi.2018.01.006. [Epub ahead of print] Spanish. No abstract available.


Neonatal Overnutrition Increases Testicular Size and Expression of Luteinizing Hormone β-Subunit in Peripubertal Male Rats.

Argente-Arizón P, Castro-González D, Díaz F, Fernández-Gómez MJ, Sánchez-Garrido MA, Tena-Sempere M, Argente J, Chowen JA.

Front Endocrinol (Lausanne). 2018 Apr 13;9:168. doi: 10.3389/fendo.2018.00168. eCollection 2018.


Nephrotic syndrome associated with severe hypertriglyceridemia in a pediatric patient: Answers.

Corredor-Andrés B, Muñoz-Calvo MT, Calero O, Aparicio C, Argente J, Calero M.

Pediatr Nephrol. 2018 Nov;33(11):2075-2078. doi: 10.1007/s00467-018-3919-1. Epub 2018 Mar 12. No abstract available.


Nephrotic syndrome associated with severe hypertriglyceridemia in a pediatric patient: Questions.

Corredor-Andrés B, Muñoz-Calvo MT, Calero O, Aparicio C, Argente J, Calero M.

Pediatr Nephrol. 2018 Nov;33(11):2073-2074. doi: 10.1007/s00467-018-3894-6. Epub 2018 Mar 12. No abstract available.


rhIGF-1 Treatment Increases Bone Mineral Density and Trabecular Bone Structure in Children with PAPP-A2 Deficiency.

Hawkins-Carranza FG, Muñoz-Calvo MT, Martos-Moreno GÁ, Allo-Miguel G, Del Río L, Pozo J, Chowen JA, Pérez-Jurado LA, Argente J.

Horm Res Paediatr. 2018;89(3):200-204. doi: 10.1159/000486336. Epub 2018 Feb 16.


[Bilateral pseudoangiomatous stromal hyperplasia of the breast].

Márquez Rivera M, Corredor Andrés B, Azorín Cuadrillero D, Muñoz Calvo MT, Argente J.

An Pediatr (Barc). 2018 Nov;89(5):309-311. doi: 10.1016/j.anpedi.2017.12.011. Epub 2018 Feb 13. Spanish. No abstract available.


The Protective Effects of IGF-I against β-Amyloid-related Downregulation of Hippocampal Somatostatinergic System Involve Activation of Akt and Protein Kinase A.

Aguado-Llera D, Canelles S, Frago LM, Chowen JA, Argente J, Arilla E, Barrios V.

Neuroscience. 2018 Mar 15;374:104-118. doi: 10.1016/j.neuroscience.2018.01.041. Epub 2018 Feb 3.


Resveratrol Intake During Pregnancy and Lactation Modulates the Early Metabolic Effects of Maternal Nutrition Differently in Male and Female Offspring.

Ros P, Díaz F, Freire-Regatillo A, Argente-Arizón P, Barrios V, Argente J, Chowen JA.

Endocrinology. 2018 Feb 1;159(2):810-825. doi: 10.1210/en.2017-00610.


Expanding the mutational spectrum in Johanson-Blizzard syndrome: identification of whole exon deletions and duplications in the UBR1 gene by multiplex ligation-dependent probe amplification analysis.

Sukalo M, Schäflein E, Schanze I, Everman DB, Rezaei N, Argente J, Lorda-Sanchez I, Deshpande C, Takahashi T, Kleger A, Zenker M.

Mol Genet Genomic Med. 2017 Nov;5(6):774-780. doi: 10.1002/mgg3.319. Epub 2017 Jul 31.


Estradiol Uses Different Mechanisms in Astrocytes from the Hippocampus of Male and Female Rats to Protect against Damage Induced by Palmitic Acid.

Frago LM, Canelles S, Freire-Regatillo A, Argente-Arizón P, Barrios V, Argente J, Garcia-Segura LM, Chowen JA.

Front Mol Neurosci. 2017 Oct 24;10:330. doi: 10.3389/fnmol.2017.00330. eCollection 2017.


The Hypothalamic Inflammatory/Gliosis Response to Neonatal Overnutrition Is Sex and Age Dependent.

Argente-Arizón P, Díaz F, Ros P, Barrios V, Tena-Sempere M, García-Segura LM, Argente J, Chowen JA.

Endocrinology. 2018 Jan 1;159(1):368-387. doi: 10.1210/en.2017-00539.


Evaluation of plasma cytokines in patients with cocaine use disorders in abstinence identifies transforming growth factor alpha (TGFα) as a potential biomarker of consumption and dual diagnosis.

Maza-Quiroga R, García-Marchena N, Romero-Sanchiz P, Barrios V, Pedraz M, Serrano A, Nogueira-Arjona R, Ruiz JJ, Soria M, Campos R, Chowen JA, Argente J, Torrens M, López-Gallardo M, Marco EM, Rodríguez de Fonseca F, Pavón FJ, Araos P.

PeerJ. 2017 Oct 12;5:e3926. doi: 10.7717/peerj.3926. eCollection 2017.


The increase in fiber size in male rat gastrocnemius after chronic central leptin infusion is related to activation of insulin signaling.

Burgos-Ramos E, Canelles S, Rodríguez A, Frago LM, Gómez-Ambrosi J, Chowen JA, Frühbeck G, Argente J, Barrios V.

Mol Cell Endocrinol. 2018 Jul 15;470:48-59. doi: 10.1016/j.mce.2017.09.029. Epub 2017 Sep 27.


Ghrelin: A Link Between Energy Homeostasis and the Immune System.

Chowen JA, Argente J.

Endocrinology. 2017 Jul 1;158(7):2077-2081. doi: 10.1210/en.2017-00350. No abstract available.


One level up: abnormal proteolytic regulation of IGF activity plays a role in human pathophysiology.

Argente J, Chowen JA, Pérez-Jurado LA, Frystyk J, Oxvig C.

EMBO Mol Med. 2017 Oct;9(10):1338-1345. doi: 10.15252/emmm.201707950. Review.


[Karyptype 48,XXXY/49,XXXXY and proximal radioulnar synostosis].

Girón Del Río R, Jeronimo Dos Santos T, Travieso-Suárez L, Muñoz Calvo MT, Argente J.

An Pediatr (Barc). 2018 May;88(5):282-284. doi: 10.1016/j.anpedi.2017.05.008. Epub 2017 Jul 24. Spanish. No abstract available.


[Hypophosphatasia: Clinical manifestations, diagnostic recommendations and therapeutic options].

Martos-Moreno GA, Calzada J, Couce ML, Argente J.

An Pediatr (Barc). 2018 Jun;88(6):356.e1-356.e11. doi: 10.1016/j.anpedi.2017.06.004. Epub 2017 Jul 16. Spanish.


The impact of intrauterine and extrauterine weight gain in premature infants on later body composition.

Saenz de Pipaon M, Dorronsoro I, Álvarez-Cuervo L, Butte NF, Madero R, Barrios V, Coya J, Martínez-Biarge M, Martos-Moreno GÁ, Fewtrell MS, Argente J, Quero J.

Pediatr Res. 2017 Oct;82(4):658-664. doi: 10.1038/pr.2017.123. Epub 2017 Jul 5.


Metabolomics allows the discrimination of the pathophysiological relevance of hyperinsulinism in obese prepubertal children.

Martos-Moreno GÁ, Mastrangelo A, Barrios V, García A, Chowen JA, Rupérez FJ, Barbas C, Argente J.

Int J Obes (Lond). 2017 Oct;41(10):1473-1480. doi: 10.1038/ijo.2017.137. Epub 2017 Jun 7.


Sex differences in the neuroendocrine control of metabolism and the implication of astrocytes.

Chowen JA, Argente-Arizón P, Freire-Regatillo A, Argente J.

Front Neuroendocrinol. 2018 Jan;48:3-12. doi: 10.1016/j.yfrne.2017.05.003. Epub 2017 May 25. Review.


Novel genes involved in severe early-onset obesity revealed by rare copy number and sequence variants.

Serra-Juhé C, Martos-Moreno GÁ, Bou de Pieri F, Flores R, González JR, Rodríguez-Santiago B, Argente J, Pérez-Jurado LA.

PLoS Genet. 2017 May 10;13(5):e1006657. doi: 10.1371/journal.pgen.1006657. eCollection 2017 May.


[Brachydactyly type C due to a nonsense mutation in the GDF5 gene].

Travieso-Suárez L, Pereda A, Pozo-Román J, Pérez de Nanclares G, Argente J.

An Pediatr (Barc). 2018 Feb;88(2):107-109. doi: 10.1016/j.anpedi.2017.03.001. Epub 2017 Apr 5. Spanish. No abstract available.


Non-Neuronal Cells in the Hypothalamic Adaptation to Metabolic Signals.

Freire-Regatillo A, Argente-Arizón P, Argente J, García-Segura LM, Chowen JA.

Front Endocrinol (Lausanne). 2017 Mar 21;8:51. doi: 10.3389/fendo.2017.00051. eCollection 2017. Review.


Polycystic Kidney Disease with Hyperinsulinemic Hypoglycemia Caused by a Promoter Mutation in Phosphomannomutase 2.

Cabezas OR, Flanagan SE, Stanescu H, García-Martínez E, Caswell R, Lango-Allen H, Antón-Gamero M, Argente J, Bussell AM, Brandli A, Cheshire C, Crowne E, Dumitriu S, Drynda R, Hamilton-Shield JP, Hayes W, Hofherr A, Iancu D, Issler N, Jefferies C, Jones P, Johnson M, Kesselheim A, Klootwijk E, Koettgen M, Lewis W, Martos JM, Mozere M, Norman J, Patel V, Parrish A, Pérez-Cerdá C, Pozo J, Rahman SA, Sebire N, Tekman M, Turnpenny PD, Hoff WV, Viering DHHM, Weedon MN, Wilson P, Guay-Woodford L, Kleta R, Hussain K, Ellard S, Bockenhauer D.

J Am Soc Nephrol. 2017 Aug;28(8):2529-2539. doi: 10.1681/ASN.2016121312. Epub 2017 Apr 3.


Microglial Proliferation in Obesity: When, Where, Why, and What Does It Mean?

Chowen JA, Horvath TL, Argente J.

Diabetes. 2017 Apr;66(4):804-805. doi: 10.2337/dbi16-0073. No abstract available.


Fifteen years of research on oral-facial-digital syndromes: from 1 to 16 causal genes.

Bruel AL, Franco B, Duffourd Y, Thevenon J, Jego L, Lopez E, Deleuze JF, Doummar D, Giles RH, Johnson CA, Huynen MA, Chevrier V, Burglen L, Morleo M, Desguerres I, Pierquin G, Doray B, Gilbert-Dussardier B, Reversade B, Steichen-Gersdorf E, Baumann C, Panigrahi I, Fargeot-Espaliat A, Dieux A, David A, Goldenberg A, Bongers E, Gaillard D, Argente J, Aral B, Gigot N, St-Onge J, Birnbaum D, Phadke SR, Cormier-Daire V, Eguether T, Pazour GJ, Herranz-Pérez V, Goldstein JS, Pasquier L, Loget P, Saunier S, Mégarbané A, Rosnet O, Leroux MR, Wallingford JB, Blacque OE, Nachury MV, Attie-Bitach T, Rivière JB, Faivre L, Thauvin-Robinet C.

J Med Genet. 2017 Jun;54(6):371-380. doi: 10.1136/jmedgenet-2016-104436. Epub 2017 Mar 13. Review.


Plasma Chemokines in Patients with Alcohol Use Disorders: Association of CCL11 (Eotaxin-1) with Psychiatric Comorbidity.

García-Marchena N, Araos PF, Barrios V, Sánchez-Marín L, Chowen JA, Pedraz M, Castilla-Ortega E, Romero-Sanchiz P, Ponce G, Gavito AL, Decara J, Silva D, Torrens M, Argente J, Rubio G, Serrano A, de Fonseca FR, Pavón FJ.

Front Psychiatry. 2017 Jan 18;7:214. doi: 10.3389/fpsyt.2016.00214. eCollection 2016.


Molecular and clinical analysis of ALPL in a cohort of patients with suspicion of Hypophosphatasia.

Tenorio J, Álvarez I, Riancho-Zarrabeitia L, Martos-Moreno GÁ, Mandrile G, de la Flor Crespo M, Sukchev M, Sherif M, Kramer I, Darnaude-Ortiz MT, Arias P, Gordo G, Dapía I, Martinez-Villanueva J, Gómez R, Iturzaeta JM, Otaify G, García-Unzueta M, Rubinacci A, Riancho JA, Aglan M, Temtamy S, Hamid MA, Argente J, Ruiz-Pérez VL, Heath KE, Lapunzina P.

Am J Med Genet A. 2017 Mar;173(3):601-610. doi: 10.1002/ajmg.a.37991. Epub 2017 Jan 27.


Glial cells and energy balance.

Argente-Arizón P, Guerra-Cantera S, Garcia-Segura LM, Argente J, Chowen JA.

J Mol Endocrinol. 2017 Jan;58(1):R59-R71. Epub 2016 Nov 18. Review.


Treatment With Recombinant Human Insulin-Like Growth Factor-1 Improves Growth in Patients With PAPP-A2 Deficiency.

Muñoz-Calvo MT, Barrios V, Pozo J, Chowen JA, Martos-Moreno GÁ, Hawkins F, Dauber A, Domené HM, Yakar S, Rosenfeld RG, Pérez-Jurado LA, Oxvig C, Frystyk J, Argente J.

J Clin Endocrinol Metab. 2016 Nov;101(11):3879-3883. Epub 2016 Sep 20.


Bridging the gap: metabolic and endocrine care of patients during transition.

Hokken-Koelega A, van der Lely AJ, Hauffa B, Häusler G, Johannsson G, Maghnie M, Argente J, DeSchepper J, Gleeson H, Gregory JW, Höybye C, Keleştimur F, Luger A, Müller HL, Neggers S, Popovic-Brkic V, Porcu E, Sävendahl L, Shalet S, Spiliotis B, Tauber M.

Endocr Connect. 2016 Nov;5(6):R44-R54. Epub 2016 Nov 1. Review.


Changes in Body Mass Index in Girls with Idiopathic Central Precocious Puberty under Gonadotropin-Releasing Hormone Analogue Therapy: The Spanish Registry.

Corripio R, Soriano-Guillén L, Herrero FJ, Cañete R, Castro-Feijoó L, Escribano A, Espino R, Labarta JI, Argente J.

Horm Res Paediatr. 2016;86(3):154-160. Epub 2016 Aug 13.


[Mutation in RET gene: Prophylactic thyroidectomy and postoperative follow-up].

Villamayor Martín R, Bartucci A, Muñoz Calvo MT, Pozo Román J, Argente J.

An Pediatr (Barc). 2016 Nov;85(5):266-267. doi: 10.1016/j.anpedi.2015.12.005. Epub 2016 Jan 19. Spanish. No abstract available.


Blockage of neonatal leptin signaling induces changes in the hypothalamus associated with delayed pubertal onset and modifications in neuropeptide expression during adulthood in male rats.

Mela V, Jimenez S, Freire-Regatillo A, Barrios V, Marco EM, Lopez-Rodriguez AB, Argente J, Viveros MP, Chowen JA.

Peptides. 2016 Dec;86:63-71. doi: 10.1016/j.peptides.2016.10.003. Epub 2016 Oct 14.


[Elevated thyroid hormone levels following low molecular weight heparin administration].

de Noriega Echevarría I, García-Salido A, Muñoz-Calvo MT, Argente J.

An Pediatr (Barc). 2017 Jul;87(1):50-51. doi: 10.1016/j.anpedi.2016.09.006. Epub 2016 Oct 21. Spanish. No abstract available.


[Persistent Müllerian duct syndrome due to a mutation in the anti-Müllerian hormone receptor gene (AMHR2)].

Orós-Millán ME, Muñoz-Calvo MT, Nishi MY, Bilharinho Mendonca B, Argente J.

An Pediatr (Barc). 2017 Feb;86(2):94-95. doi: 10.1016/j.anpedi.2016.06.011. Epub 2016 Jul 22. Spanish. No abstract available.


Acquired partial lipodystrophy (Barraquer-Simons syndrome) and IgA nephropathy.

de Lucas-Collantes C, Pozo-Román J, Aparicio-López C, de Prada-Vicente I, Argente J.

Nefrologia. 2016 Sep - Oct;36(5):556-558. doi: 10.1016/j.nefro.2016.03.003. Epub 2016 May 30. English, Spanish. No abstract available.


[X-linked hypophosphatemic rickets due to mutations in PHEX: Clinical and evolutionary variability].

Martos Moreno GÁ, Aparicio C, de Lucas C, Gil Peña H, Argente J.

An Pediatr (Barc). 2016 Jul;85(1):41-3. doi: 10.1016/j.anpedi.2016.04.012. Epub 2016 May 21. Spanish. No abstract available.


Age and sex dependent effects of early overnutrition on metabolic parameters and the role of neonatal androgens.

Argente-Arizón P, Ros P, Díaz F, Fuente-Martin E, Castro-González D, Sánchez-Garrido MÁ, Barrios V, Tena-Sempere M, Argente J, Chowen JA.

Biol Sex Differ. 2016 May 18;7:26. doi: 10.1186/s13293-016-0079-5. eCollection 2016.

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