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Items: 1 to 50 of 213

1.

Associations of variants In the hexokinase 1 and interleukin 18 receptor regions with oxyhemoglobin saturation during sleep.

Cade BE, Chen H, Stilp AM, Louie T, Ancoli-Israel S, Arens R, Barfield R, Below JE, Cai J, Conomos MP, Evans DS, Frazier-Wood AC, Gharib SA, Gleason KJ, Gottlieb DJ, Hillman DR, Johnson WC, Lederer DJ, Lee J, Loredo JS, Mei H, Mukherjee S, Patel SR, Post WS, Purcell SM, Ramos AR, Reid KJ, Rice K, Shah NA, Sofer T, Taylor KD, Thornton TA, Wang H, Yaffe K, Zee PC, Hanis CL, Palmer LJ, Rotter JI, Stone KL, Tranah GJ, Wilson JG, Sunyaev SR, Laurie CC, Zhu X, Saxena R, Lin X, Redline S.

PLoS Genet. 2019 Apr 16;15(4):e1007739. doi: 10.1371/journal.pgen.1007739. eCollection 2019 Apr.

2.

The hallmarks of CMV-specific CD8 T-cell differentiation.

van den Berg SPH, Pardieck IN, Lanfermeijer J, Sauce D, Klenerman P, van Baarle D, Arens R.

Med Microbiol Immunol. 2019 Apr 13. doi: 10.1007/s00430-019-00608-7. [Epub ahead of print] Review.

PMID:
30989333
3.

Peripheral and systemic antigens elicit an expandable pool of resident memory CD8+ T cells in the bone marrow.

Pascutti MF, Geerman S, Collins N, Brasser G, Nota B, Stark R, Behr F, Oja A, Slot E, Panagioti E, Prier JE, Hickson S, Wolkers MC, Heemskerk MHM, Hombrink P, Arens R, Mackay LK, van Gisbergen KPJM, Nolte MA.

Eur J Immunol. 2019 Jun;49(6):853-872. doi: 10.1002/eji.201848003. Epub 2019 Apr 2.

PMID:
30891737
4.

T cell co-stimulation and co-inhibition in cardiovascular disease: a double-edged sword.

Simons KH, de Jong A, Jukema JW, de Vries MR, Arens R, Quax PHA.

Nat Rev Cardiol. 2019 Jun;16(6):325-343. doi: 10.1038/s41569-019-0164-7. Review.

PMID:
30770894
5.

Demarcated thresholds of tumor-specific CD8 T cells elicited by MCMV-based vaccine vectors provide robust correlates of protection.

Beyranvand Nejad E, Ratts RB, Panagioti E, Meyer C, Oduro JD, Cicin-Sain L, Früh K, van der Burg SH, Arens R.

J Immunother Cancer. 2019 Jan 31;7(1):25. doi: 10.1186/s40425-019-0500-9.

6.

T RM maintenance is regulated by tissue damage via P2RX7.

Stark R, Wesselink TH, Behr FM, Kragten NAM, Arens R, Koch-Nolte F, van Gisbergen KPJM, van Lier RAW.

Sci Immunol. 2018 Dec 14;3(30). pii: eaau1022. doi: 10.1126/sciimmunol.aau1022.

PMID:
30552101
7.

Cytofast: A workflow for visual and quantitative analysis of flow and mass cytometry data to discover immune signatures and correlations.

Beyrend G, Stam K, Höllt T, Ossendorp F, Arens R.

Comput Struct Biotechnol J. 2018 Oct 24;16:435-442. doi: 10.1016/j.csbj.2018.10.004. eCollection 2018.

8.

Admixture mapping identifies novel loci for obstructive sleep apnea in Hispanic/Latino Americans.

Wang H, Cade BE, Sofer T, Sands SA, Chen H, Browning SR, Stilp AM, Louie TL, Thornton TA, Johnson WC, Below JE, Conomos MP, Evans DS, Gharib SA, Guo X, Wood AC, Mei H, Yaffe K, Loredo JS, Ramos AR, Barrett-Connor E, Ancoli-Israel S, Zee PC, Arens R, Shah NA, Taylor KD, Tranah GJ, Stone KL, Hanis CL, Wilson JG, Gottlieb DJ, Patel SR, Rice K, Post WS, Rotter JI, Sunyaev SR, Cai J, Lin X, Purcell SM, Laurie CC, Saxena R, Redline S, Zhu X.

Hum Mol Genet. 2019 Feb 15;28(4):675-687. doi: 10.1093/hmg/ddy387.

PMID:
30403821
9.

Cytomegalovirus infection and progressive differentiation of effector-memory T cells.

Pardieck IN, Beyrend G, Redeker A, Arens R.

F1000Res. 2018 Sep 26;7. pii: F1000 Faculty Rev-1554. doi: 10.12688/f1000research.15753.1. eCollection 2018. Review.

10.

Depressive symptomatology in school-aged children with obstructive sleep apnea syndrome: incidence, demographic factors, and changes following a randomized controlled trial of adenotonsillectomy.

Hodges E, Marcus CL, Kim JY, Xanthopoulos M, Shults J, Giordani B, Beebe DW, Rosen CL, Chervin RD, Mitchell RB, Katz ES, Gozal D, Redline S, Elden L, Arens R, Moore R, Taylor HG, Radcliffe J, Thomas NH.

Sleep. 2018 Dec 1;41(12). doi: 10.1093/sleep/zsy180.

PMID:
30212861
11.

OX40 Stimulation Enhances Protective Immune Responses Induced After Vaccination With Attenuated Malaria Parasites.

Othman AS, Franke-Fayard BM, Imai T, van der Gracht ETI, Redeker A, Salman AM, Marin-Mogollon C, Ramesar J, Chevalley-Maurel S, Janse CJ, Arens R, Khan SM.

Front Cell Infect Microbiol. 2018 Jul 19;8:247. doi: 10.3389/fcimb.2018.00247. eCollection 2018.

12.

FcγRI expression on macrophages is required for antibody-mediated tumor protection by cytomegalovirus-based vaccines.

Benonisson H, Sow HS, Breukel C, Claassens JWC, Brouwers C, Linssen MM, Redeker A, Fransen MF, van Hall T, Ossendorp F, Arens R, Verbeek S.

Oncotarget. 2018 Jun 29;9(50):29392-29402. doi: 10.18632/oncotarget.25630. eCollection 2018 Jun 29.

13.

Impact of congenital cytomegalovirus infection on transcriptomes from archived dried blood spots in relation to long-term clinical outcome.

Rovito R, Warnatz HJ, Kiełbasa SM, Mei H, Amstislavskiy V, Arens R, Yaspo ML, Lehrach H, Kroes ACM, Goeman JJ, Vossen ACTM.

PLoS One. 2018 Jul 19;13(7):e0200652. doi: 10.1371/journal.pone.0200652. eCollection 2018.

14.

Biomechanics of the soft-palate in sleep apnea patients with polycystic ovarian syndrome.

Subramaniam DR, Arens R, Wagshul ME, Sin S, Wootton DM, Gutmark EJ.

J Biomech. 2018 Jul 25;76:8-15. doi: 10.1016/j.jbiomech.2018.05.013. Epub 2018 May 17.

PMID:
29793766
15.

A flexible MHC class I multimer loading system for large-scale detection of antigen-specific T cells.

Luimstra JJ, Garstka MA, Roex MCJ, Redeker A, Janssen GMC, van Veelen PA, Arens R, Falkenburg JHF, Neefjes J, Ovaa H.

J Exp Med. 2018 May 7;215(5):1493-1504. doi: 10.1084/jem.20180156. Epub 2018 Apr 17.

16.

The role of CD27-CD70-mediated T cell co-stimulation in vasculogenesis, arteriogenesis and angiogenesis.

Simons KH, Aref Z, Peters HAB, Welten SP, Nossent AY, Jukema JW, Hamming JF, Arens R, de Vries MR, Quax PHA.

Int J Cardiol. 2018 Jun 1;260:184-190. doi: 10.1016/j.ijcard.2018.02.015.

17.

Features of Effective T Cell-Inducing Vaccines against Chronic Viral Infections.

Panagioti E, Klenerman P, Lee LN, van der Burg SH, Arens R.

Front Immunol. 2018 Feb 16;9:276. doi: 10.3389/fimmu.2018.00276. eCollection 2018. Review.

18.

The Contribution of Cytomegalovirus Infection to Immune Senescence Is Set by the Infectious Dose.

Redeker A, Remmerswaal EBM, van der Gracht ETI, Welten SPM, Höllt T, Koning F, Cicin-Sain L, Nikolich-Žugich J, Ten Berge IJM, van Lier RAW, van Unen V, Arens R.

Front Immunol. 2018 Jan 10;8:1953. doi: 10.3389/fimmu.2017.01953. eCollection 2017.

19.

Exhaustion and Inflation at Antipodes of T Cell Responses to Chronic Virus Infection.

Cicin-Sain L, Arens R.

Trends Microbiol. 2018 Jun;26(6):498-509. doi: 10.1016/j.tim.2017.11.012. Epub 2017 Dec 14. Review.

PMID:
29249600
20.

Multiethnic Meta-Analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea-related Quantitative Trait Locus in Men.

Chen H, Cade BE, Gleason KJ, Bjonnes AC, Stilp AM, Sofer T, Conomos MP, Ancoli-Israel S, Arens R, Azarbarzin A, Bell GI, Below JE, Chun S, Evans DS, Ewert R, Frazier-Wood AC, Gharib SA, Haba-Rubio J, Hagen EW, Heinzer R, Hillman DR, Johnson WC, Kutalik Z, Lane JM, Larkin EK, Lee SK, Liang J, Loredo JS, Mukherjee S, Palmer LJ, Papanicolaou GJ, Penzel T, Peppard PE, Post WS, Ramos AR, Rice K, Rotter JI, Sands SA, Shah NA, Shin C, Stone KL, Stubbe B, Sul JH, Tafti M, Taylor KD, Teumer A, Thornton TA, Tranah GJ, Wang C, Wang H, Warby SC, Wellman DA, Zee PC, Hanis CL, Laurie CC, Gottlieb DJ, Patel SR, Zhu X, Sunyaev SR, Saxena R, Lin X, Redline S.

Am J Respir Cell Mol Biol. 2018 Mar;58(3):391-401. doi: 10.1165/rcmb.2017-0237OC.

21.

Human plasmacytoid dendritic cells acquire phagocytic capacity by TLR9 ligation in the presence of soluble factors produced by renal epithelial cells.

Ruben JM, García-Romo GS, Breman E, van der Kooij S, Redeker A, Arens R, van Kooten C.

Kidney Int. 2018 Feb;93(2):355-364. doi: 10.1016/j.kint.2017.08.006. Epub 2017 Oct 20.

PMID:
29061332
22.

CMV immune evasion and manipulation of the immune system with aging.

Jackson SE, Redeker A, Arens R, van Baarle D, van den Berg SPH, Benedict CA, Čičin-Šain L, Hill AB, Wills MR.

Geroscience. 2017 Jun;39(3):273-291. doi: 10.1007/s11357-017-9986-6. Epub 2017 Jun 24.

23.

CD4+ T Cell and NK Cell Interplay Key to Regression of MHC Class Ilow Tumors upon TLR7/8 Agonist Therapy.

Doorduijn EM, Sluijter M, Salvatori DC, Silvestri S, Maas S, Arens R, Ossendorp F, van der Burg SH, van Hall T.

Cancer Immunol Res. 2017 Aug;5(8):642-653. doi: 10.1158/2326-6066.CIR-16-0334. Epub 2017 Jun 21.

24.

Sleep and Breathing the First Night After Adenotonsillectomy in Obese Children With Obstructive Sleep Apnea.

De A, Waltuch T, Gonik NJ, Nguyen-Famulare N, Muzumdar H, Bent JP, Isasi CR, Sin S, Arens R.

J Clin Sleep Med. 2017 Jun 15;13(6):805-811. doi: 10.5664/jcsm.6620.

25.

Inhibition of 14q32 microRNA miR-495 reduces lesion formation, intimal hyperplasia and plasma cholesterol levels in experimental restenosis.

Welten SMJ, de Jong RCM, Wezel A, de Vries MR, Boonstra MC, Parma L, Jukema JW, van der Sluis TC, Arens R, Bot I, Agrawal S, Quax PHA, Nossent AY.

Atherosclerosis. 2017 Jun;261:26-36. doi: 10.1016/j.atherosclerosis.2017.04.011. Epub 2017 Apr 13.

26.

Cytomegalovirus infection exacerbates autoimmune mediated neuroinflammation.

Vanheusden M, Broux B, Welten SPM, Peeters LM, Panagioti E, Van Wijmeersch B, Somers V, Stinissen P, Arens R, Hellings N.

Sci Rep. 2017 Apr 6;7(1):663. doi: 10.1038/s41598-017-00645-3.

27.

The Effects of Obstructive Sleep Apnea Syndrome on the Dentate Gyrus and Learning and Memory in Children.

Cha J, Zea-Hernandez JA, Sin S, Graw-Panzer K, Shifteh K, Isasi CR, Wagshul ME, Moran EE, Posner J, Zimmerman ME, Arens R.

J Neurosci. 2017 Apr 19;37(16):4280-4288. doi: 10.1523/JNEUROSCI.3583-16.2017. Epub 2017 Mar 20.

28.

Enforced OX40 Stimulation Empowers Booster Vaccines to Induce Effective CD4+ and CD8+ T Cell Responses against Mouse Cytomegalovirus Infection.

Panagioti E, Boon L, Arens R, van der Burg SH.

Front Immunol. 2017 Feb 20;8:144. doi: 10.3389/fimmu.2017.00144. eCollection 2017.

29.

Effects of Adenotonsillectomy on Parent-Reported Behavior in Children With Obstructive Sleep Apnea.

Thomas NH, Xanthopoulos MS, Kim JY, Shults J, Escobar E, Giordani B, Hodges E, Chervin RD, Paruthi S, Rosen CL, Taylor GH, Arens R, Katz ES, Beebe DW, Redline S, Radcliffe J, Marcus CL.

Sleep. 2017 Apr 1;40(4). doi: 10.1093/sleep/zsx018.

30.

Peptide Processing Is Critical for T-Cell Memory Inflation and May Be Optimized to Improve Immune Protection by CMV-Based Vaccine Vectors.

Dekhtiarenko I, Ratts RB, Blatnik R, Lee LN, Fischer S, Borkner L, Oduro JD, Marandu TF, Hoppe S, Ruzsics Z, Sonnemann JK, Mansouri M, Meyer C, Lemmermann NA, Holtappels R, Arens R, Klenerman P, Früh K, Reddehase MJ, Riemer AB, Cicin-Sain L.

PLoS Pathog. 2016 Dec 15;12(12):e1006072. doi: 10.1371/journal.ppat.1006072. eCollection 2016 Dec.

31.

Wnt Signaling as Master Regulator of T-Lymphocyte Responses: Implications for Transplant Therapy.

Staal FJ, Arens R.

Transplantation. 2016 Dec;100(12):2584-2592. Review.

PMID:
27861287
32.

The importance of correctly timing cancer immunotherapy.

Beyranvand Nejad E, Welters MJ, Arens R, van der Burg SH.

Expert Opin Biol Ther. 2017 Jan;17(1):87-103. Epub 2016 Nov 16. Review.

PMID:
27802061
33.

Improving Adoptive T Cell Therapy: The Particular Role of T Cell Costimulation, Cytokines, and Post-Transfer Vaccination.

Redeker A, Arens R.

Front Immunol. 2016 Sep 6;7:345. doi: 10.3389/fimmu.2016.00345. eCollection 2016. Review.

34.

The Breadth of Synthetic Long Peptide Vaccine-Induced CD8+ T Cell Responses Determines the Efficacy against Mouse Cytomegalovirus Infection.

Panagioti E, Redeker A, van Duikeren S, Franken KL, Drijfhout JW, van der Burg SH, Arens R.

PLoS Pathog. 2016 Sep 16;12(9):e1005895. doi: 10.1371/journal.ppat.1005895. eCollection 2016 Sep.

35.

Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8+ T Cells.

Beyranvand Nejad E, van der Sluis TC, van Duikeren S, Yagita H, Janssen GM, van Veelen PA, Melief CJ, van der Burg SH, Arens R.

Cancer Res. 2016 Oct 15;76(20):6017-6029. Epub 2016 Aug 28.

36.

MR Image Analytics to Characterize the Upper Airway Structure in Obese Children with Obstructive Sleep Apnea Syndrome.

Tong Y, Udupa JK, Sin S, Liu Z, Wileyto EP, Torigian DA, Arens R.

PLoS One. 2016 Aug 3;11(8):e0159327. doi: 10.1371/journal.pone.0159327. eCollection 2016.

37.

Cognitive Effects of Adenotonsillectomy for Obstructive Sleep Apnea.

Taylor HG, Bowen SR, Beebe DW, Hodges E, Amin R, Arens R, Chervin RD, Garetz SL, Katz ES, Moore RH, Morales KH, Muzumdar H, Paruthi S, Rosen CL, Sadhwani A, Thomas NH, Ware J, Marcus CL, Ellenberg SS, Redline S, Giordani B.

Pediatrics. 2016 Aug;138(2). pii: e20154458. doi: 10.1542/peds.2015-4458.

38.

Computational fluid dynamics upper airway effective compliance, critical closing pressure, and obstructive sleep apnea severity in obese adolescent girls.

Wootton DM, Sin S, Luo H, Yazdani A, McDonough JM, Wagshul ME, Isasi CR, Arens R.

J Appl Physiol (1985). 2016 Oct 1;121(4):925-931. doi: 10.1152/japplphysiol.00190.2016. Epub 2016 Jul 21.

39.

Minimally interactive segmentation of 4D dynamic upper airway MR images via fuzzy connectedness.

Tong Y, Udupa JK, Odhner D, Wu C, Sin S, Wagshul ME, Arens R.

Med Phys. 2016 May;43(5):2323. doi: 10.1118/1.4945698.

40.

An Official American Thoracic Society Clinical Practice Guideline: Pediatric Chronic Home Invasive Ventilation.

Sterni LM, Collaco JM, Baker CD, Carroll JL, Sharma GD, Brozek JL, Finder JD, Ackerman VL, Arens R, Boroughs DS, Carter J, Daigle KL, Dougherty J, Gozal D, Kevill K, Kravitz RM, Kriseman T, MacLusky I, Rivera-Spoljaric K, Tori AJ, Ferkol T, Halbower AC; ATS Pediatric Chronic Home Ventilation Workgroup.

Am J Respir Crit Care Med. 2016 Apr 15;193(8):e16-35. doi: 10.1164/rccm.201602-0276ST.

41.

Vaccination during myeloid cell depletion by cancer chemotherapy fosters robust T cell responses.

Welters MJ, van der Sluis TC, van Meir H, Loof NM, van Ham VJ, van Duikeren S, Santegoets SJ, Arens R, de Kam ML, Cohen AF, van Poelgeest MI, Kenter GG, Kroep JR, Burggraaf J, Melief CJ, van der Burg SH.

Sci Transl Med. 2016 Apr 13;8(334):334ra52. doi: 10.1126/scitranslmed.aad8307.

PMID:
27075626
42.

Association of glucose homeostasis measures with heart rate variability among Hispanic/Latino adults without diabetes: the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

Meyer ML, Gotman NM, Soliman EZ, Whitsel EA, Arens R, Cai J, Daviglus ML, Denes P, González HM, Moreiras J, Talavera GA, Heiss G.

Cardiovasc Diabetol. 2016 Mar 16;15:45. doi: 10.1186/s12933-016-0364-y.

43.

Genetic Associations with Obstructive Sleep Apnea Traits in Hispanic/Latino Americans.

Cade BE, Chen H, Stilp AM, Gleason KJ, Sofer T, Ancoli-Israel S, Arens R, Bell GI, Below JE, Bjonnes AC, Chun S, Conomos MP, Evans DS, Johnson WC, Frazier-Wood AC, Lane JM, Larkin EK, Loredo JS, Post WS, Ramos AR, Rice K, Rotter JI, Shah NA, Stone KL, Taylor KD, Thornton TA, Tranah GJ, Wang C, Zee PC, Hanis CL, Sunyaev SR, Patel SR, Laurie CC, Zhu X, Saxena R, Lin X, Redline S.

Am J Respir Crit Care Med. 2016 Oct 1;194(7):886-897.

44.

Vaccines for established cancer: overcoming the challenges posed by immune evasion.

van der Burg SH, Arens R, Ossendorp F, van Hall T, Melief CJ.

Nat Rev Cancer. 2016 Apr;16(4):219-33. doi: 10.1038/nrc.2016.16. Epub 2016 Mar 11. Review.

PMID:
26965076
45.

Viral Persistence Induces Antibody Inflation without Altering Antibody Avidity.

Welten SPM, Redeker A, Toes REM, Arens R.

J Virol. 2016 Apr 14;90(9):4402-4411. doi: 10.1128/JVI.03177-15. Print 2016 May.

46.

In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity.

Halle S, Keyser KA, Stahl FR, Busche A, Marquardt A, Zheng X, Galla M, Heissmeyer V, Heller K, Boelter J, Wagner K, Bischoff Y, Martens R, Braun A, Werth K, Uvarovskii A, Kempf H, Meyer-Hermann M, Arens R, Kremer M, Sutter G, Messerle M, Förster R.

Immunity. 2016 Feb 16;44(2):233-45. doi: 10.1016/j.immuni.2016.01.010. Epub 2016 Feb 9.

47.

Intracapsular and Extracapsular Tonsillectomy and Adenoidectomy in Pediatric Obstructive Sleep Apnea.

Mukhatiyar P, Nandalike K, Cohen HW, Sin S, Gangar M, Bent JP, Arens R.

JAMA Otolaryngol Head Neck Surg. 2016 Jan;142(1):25-31. doi: 10.1001/jamaoto.2015.2603.

PMID:
26583828
48.

Murine cytomegalovirus (CMV) infection via the intranasal route offers a robust model of immunity upon mucosal CMV infection.

Oduro JD, Redeker A, Lemmermann NA, Ebermann L, Marandu TF, Dekhtiarenko I, Holzki JK, Busch DH, Arens R, Čičin-Šain L.

J Gen Virol. 2016 Jan;97(1):185-95. doi: 10.1099/jgv.0.000339. Epub 2015 Nov 10.

PMID:
26555192
49.

The Quantity of Autocrine IL-2 Governs the Expansion Potential of CD8+ T Cells.

Redeker A, Welten SP, Baert MR, Vloemans SA, Tiemessen MM, Staal FJ, Arens R.

J Immunol. 2015 Nov 15;195(10):4792-801. doi: 10.4049/jimmunol.1501083. Epub 2015 Oct 9.

50.

Clinical utility of magnetic resonance imaging and ultrasonography for diagnosis of polycystic ovary syndrome in adolescent girls.

Kenigsberg LE, Agarwal C, Sin S, Shifteh K, Isasi CR, Crespi R, Ivanova J, Coupey SM, Heptulla RA, Arens R.

Fertil Steril. 2015 Nov;104(5):1302-9.e1-4. doi: 10.1016/j.fertnstert.2015.08.002. Epub 2015 Sep 3.

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