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Items: 33


Taking aim at a challenging target in pre-clinical models of prostate cancer.

Arendt LM.

Transl Androl Urol. 2019 Mar;8(Suppl 1):S88-S90. doi: 10.21037/tau.2019.01.02. No abstract available.


Mammary adipose stromal cells derived from obese women reduce sensitivity to the aromatase inhibitor anastrazole in an organotypic breast model.

Morgan MM, Arendt LM, Alarid ET, Beebe DJ, Johnson BP.

FASEB J. 2019 Jul;33(7):8623-8633. doi: 10.1096/fj.201802347RRR. Epub 2019 Apr 19.


Obesity-Activated Adipose-Derived Stromal Cells Promote Breast Cancer Growth and Invasion.

Hillers LE, D'Amato JV, Chamberlin T, Paderta G, Arendt LM.

Neoplasia. 2018 Nov;20(11):1161-1174. doi: 10.1016/j.neo.2018.09.004. Epub 2018 Oct 12.


Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity.

Chamberlin T, D'Amato JV, Arendt LM.

Breast Cancer Res. 2017 Nov 29;19(1):128. doi: 10.1186/s13058-017-0921-7.


Automated quantification of three-dimensional organization of fiber-like structures in biological tissues.

Liu Z, Pouli D, Sood D, Sundarakrishnan A, Hui Mingalone CK, Arendt LM, Alonzo C, Quinn KP, Kuperwasser C, Zeng L, Schnelldorfer T, Kaplan DL, Georgakoudi I.

Biomaterials. 2017 Feb;116:34-47. doi: 10.1016/j.biomaterials.2016.11.041. Epub 2016 Nov 25.


Modeling Breast Tumor Development with a Humanized Mouse Model.

Arendt LM.

Methods Mol Biol. 2016;1458:247-59. doi: 10.1007/978-1-4939-3801-8_18.


Growth of human breast tissues from patient cells in 3D hydrogel scaffolds.

Sokol ES, Miller DH, Breggia A, Spencer KC, Arendt LM, Gupta PB.

Breast Cancer Res. 2016 Mar 1;18(1):19. doi: 10.1186/s13058-016-0677-5.


Working stiff: how obesity boosts cancer risk.

Arendt LM, Kuperwasser C.

Sci Transl Med. 2015 Aug 19;7(301):301fs34. doi: 10.1126/scitranslmed.aac9446.


Form and function: how estrogen and progesterone regulate the mammary epithelial hierarchy.

Arendt LM, Kuperwasser C.

J Mammary Gland Biol Neoplasia. 2015 Jun;20(1-2):9-25. doi: 10.1007/s10911-015-9337-0. Epub 2015 Jul 19. Review.


Ultra-sensitive protein detection via Single Molecule Arrays towards early stage cancer monitoring.

Schubert SM, Arendt LM, Zhou W, Baig S, Walter SR, Buchsbaum RJ, Kuperwasser C, Walt DR.

Sci Rep. 2015 Jun 8;5:11034. doi: 10.1038/srep11034.


Humanization of the mouse mammary gland.

Wronski A, Arendt LM, Kuperwasser C.

Methods Mol Biol. 2015;1293:173-86. doi: 10.1007/978-1-4939-2519-3_10.


CoREST1 promotes tumor formation and tumor stroma interactions in a mouse model of breast cancer.

Mazumdar S, Arendt LM, Phillips S, Sedic M, Kuperwasser C, Gill G.

PLoS One. 2015 Mar 20;10(3):e0121281. doi: 10.1371/journal.pone.0121281. eCollection 2015.


Human breast progenitor cell numbers are regulated by WNT and TBX3.

Arendt LM, St Laurent J, Wronski A, Caballero S, Lyle SR, Naber SP, Kuperwasser C.

PLoS One. 2014 Oct 28;9(10):e111442. doi: 10.1371/journal.pone.0111442. eCollection 2014.


Anatomical localization of progenitor cells in human breast tissue reveals enrichment of uncommitted cells within immature lobules.

Arendt LM, Keller PJ, Skibinski A, Goncalves K, Naber SP, Buchsbaum RJ, Gilmore H, Come SE, Kuperwasser C.

Breast Cancer Res. 2014 Oct 15;16(5):453. doi: 10.1186/s13058-014-0453-3.


Pregnancy-associated breast cancers are driven by differences in adipose stromal cells present during lactation.

McCready J, Arendt LM, Glover E, Iyer V, Briendel JL, Lyle SR, Naber SP, Jay DG, Kuperwasser C.

Breast Cancer Res. 2014 Jan 9;16(1):R2. doi: 10.1186/bcr3594.


Obesity promotes breast cancer by CCL2-mediated macrophage recruitment and angiogenesis.

Arendt LM, McCready J, Keller PJ, Baker DD, Naber SP, Seewaldt V, Kuperwasser C.

Cancer Res. 2013 Oct 1;73(19):6080-93. doi: 10.1158/0008-5472.CAN-13-0926. Epub 2013 Aug 19.


Prolactin promotes mammary pathogenesis independently from cyclin D1.

Asher JM, O'Leary KA, Rugowski DE, Arendt LM, Schuler LA.

Am J Pathol. 2012 Jul;181(1):294-302. doi: 10.1016/j.ajpath.2012.03.041. Epub 2012 May 29.


Estrogen promotes ER-negative tumor growth and angiogenesis through mobilization of bone marrow-derived monocytes.

Iyer V, Klebba I, McCready J, Arendt LM, Betancur-Boissel M, Wu MF, Zhang X, Lewis MT, Kuperwasser C.

Cancer Res. 2012 Jun 1;72(11):2705-13. doi: 10.1158/0008-5472.CAN-11-3287. Epub 2012 Mar 30.


Stem cell maintenance of the mammary gland: it takes two.

Keller PJ, Arendt LM, Kuperwasser C.

Cell Stem Cell. 2011 Dec 2;9(6):496-7. doi: 10.1016/j.stem.2011.11.008.


Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells.

Rudnick JA, Arendt LM, Klebba I, Hinds JW, Iyer V, Gupta PB, Naber SP, Kuperwasser C.

PLoS One. 2011;6(9):e24605. doi: 10.1371/journal.pone.0024605. Epub 2011 Sep 21.


Defining the cellular precursors to human breast cancer.

Keller PJ, Arendt LM, Skibinski A, Logvinenko T, Klebba I, Dong S, Smith AE, Prat A, Perou CM, Gilmore H, Schnitt S, Naber SP, Garlick JA, Kuperwasser C.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2772-7. doi: 10.1073/pnas.1017626108. Epub 2011 Sep 21.


Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state.

Chaffer CL, Brueckmann I, Scheel C, Kaestli AJ, Wiggins PA, Rodrigues LO, Brooks M, Reinhardt F, Su Y, Polyak K, Arendt LM, Kuperwasser C, Bierie B, Weinberg RA.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):7950-5. doi: 10.1073/pnas.1102454108. Epub 2011 Apr 15.


Prolactin-induced mouse mammary carcinomas model estrogen resistant luminal breast cancer.

Arendt LM, Rugowski DE, Grafwallner-Huseth TA, Garcia-Barchino MJ, Rui H, Schuler LA.

Breast Cancer Res. 2011 Jan 28;13(1):R11. doi: 10.1186/bcr2819.


Mapping the cellular and molecular heterogeneity of normal and malignant breast tissues and cultured cell lines.

Keller PJ, Lin AF, Arendt LM, Klebba I, Jones AD, Rudnick JA, DiMeo TA, Gilmore H, Jefferson DM, Graham RA, Naber SP, Schnitt S, Kuperwasser C.

Breast Cancer Res. 2010;12(5):R87. doi: 10.1186/bcr2755. Epub 2010 Oct 21.


The contribution of dynamic stromal remodeling during mammary development to breast carcinogenesis.

McCready J, Arendt LM, Rudnick JA, Kuperwasser C.

Breast Cancer Res. 2010;12(3):205. doi: 10.1186/bcr2578. Epub 2010 Jun 17. Review.


Stroma in breast development and disease.

Arendt LM, Rudnick JA, Keller PJ, Kuperwasser C.

Semin Cell Dev Biol. 2010 Feb;21(1):11-8. doi: 10.1016/j.semcdb.2009.10.003. Epub 2009 Oct 24. Review.


Ovarian hormones are not required for PRL-induced mammary tumorigenesis, but estrogen enhances neoplastic processes.

Arendt LM, Evans LC, Rugowski DE, Garcia-Barchino MJ, Rui H, Schuler LA.

J Endocrinol. 2009 Oct;203(1):99-110. doi: 10.1677/JOE-09-0221. Epub 2009 Jul 27.


Complex prolactin crosstalk in breast cancer: new therapeutic implications.

Carver KC, Arendt LM, Schuler LA.

Mol Cell Endocrinol. 2009 Aug 13;307(1-2):1-7. doi: 10.1016/j.mce.2009.03.014. Epub 2009 Apr 1.


Prolactin-growth factor crosstalk reduces mammary estrogen responsiveness despite elevated ERalpha expression.

Arendt LM, Grafwallner-Huseth TL, Schuler LA.

Am J Pathol. 2009 Mar;174(3):1065-74. doi: 10.2353/ajpath.2009.080719. Epub 2009 Jan 29.


Transgenic models to study actions of prolactin in mammary neoplasia.

Arendt LM, Schuler LA.

J Mammary Gland Biol Neoplasia. 2008 Mar;13(1):29-40. doi: 10.1007/s10911-008-9073-9. Epub 2008 Jan 25. Review.


Prolactin potentiates transforming growth factor alpha induction of mammary neoplasia in transgenic mice.

Arendt LM, Rose-Hellekant TA, Sandgren EP, Schuler LA.

Am J Pathol. 2006 Apr;168(4):1365-74.


Prolactin induces ERalpha-positive and ERalpha-negative mammary cancer in transgenic mice.

Rose-Hellekant TA, Arendt LM, Schroeder MD, Gilchrist K, Sandgren EP, Schuler LA.

Oncogene. 2003 Jul 24;22(30):4664-74.

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