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Items: 4

1.

Novel Therapeutic Approaches Targeting the Renin-Angiotensin System and Associated Peptides in Hypertension and Heart Failure.

Arendse LB, Danser AHJ, Poglitsch M, Touyz RM, Burnett JC Jr, Llorens-Cortes C, Ehlers MR, Sturrock ED.

Pharmacol Rev. 2019 Oct;71(4):539-570. doi: 10.1124/pr.118.017129. Review.

PMID:
31537750
2.

Structural basis for the C-domain-selective angiotensin-converting enzyme inhibition by bradykinin-potentiating peptide b (BPPb).

Sturrock ED, Lubbe L, Cozier GE, Schwager SLU, Arowolo AT, Arendse LB, Belcher E, Acharya KR.

Biochem J. 2019 May 31;476(10):1553-1570. doi: 10.1042/BCJ20190290.

PMID:
31072910
3.

Molecular Basis for Multiple Omapatrilat Binding Sites within the ACE C-Domain: Implications for Drug Design.

Cozier GE, Arendse LB, Schwager SL, Sturrock ED, Acharya KR.

J Med Chem. 2018 Nov 21;61(22):10141-10154. doi: 10.1021/acs.jmedchem.8b01309. Epub 2018 Nov 7.

PMID:
30372620
4.

Effects of polymorphic variation on the thermostability of heterogenous populations of CYP3A4 and CYP2C9 enzymes in solution.

Arendse LB, Blackburn JM.

Sci Rep. 2018 Aug 8;8(1):11876. doi: 10.1038/s41598-018-30195-1.

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