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Items: 13

1.

Frequency-dependent exacerbation of Alzheimer's disease neuropathophysiology.

Kastanenka KV, Calvo-Rodriguez M, Hou SS, Zhou H, Takeda S, Arbel-Ornath M, Lariviere A, Lee YF, Kim A, Hawkes JM, Logan R, Feng D, Chen X, Gomperts SN, Bacskai BJ.

Sci Rep. 2019 Jun 20;9(1):8964. doi: 10.1038/s41598-019-44964-z.

2.

An acute functional screen identifies an effective antibody targeting amyloid-β oligomers based on calcium imaging.

Wang X, Kastanenka KV, Arbel-Ornath M, Commins C, Kuzuya A, Lariviere AJ, Krafft GA, Hefti F, Jerecic J, Bacskai BJ.

Sci Rep. 2018 Mar 15;8(1):4634. doi: 10.1038/s41598-018-22979-2.

3.

Soluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain.

Arbel-Ornath M, Hudry E, Boivin JR, Hashimoto T, Takeda S, Kuchibhotla KV, Hou S, Lattarulo CR, Belcher AM, Shakerdge N, Trujillo PB, Muzikansky A, Betensky RA, Hyman BT, Bacskai BJ.

Mol Neurodegener. 2017 Mar 21;12(1):27. doi: 10.1186/s13024-017-0169-9.

4.

Lymphatic Clearance of the Brain: Perivascular, Paravascular and Significance for Neurodegenerative Diseases.

Bakker EN, Bacskai BJ, Arbel-Ornath M, Aldea R, Bedussi B, Morris AW, Weller RO, Carare RO.

Cell Mol Neurobiol. 2016 Mar;36(2):181-94. doi: 10.1007/s10571-015-0273-8. Epub 2016 Mar 18. Review.

5.

Topological analyses in APP/PS1 mice reveal that astrocytes do not migrate to amyloid-β plaques.

Galea E, Morrison W, Hudry E, Arbel-Ornath M, Bacskai BJ, Gómez-Isla T, Stanley HE, Hyman BT.

Proc Natl Acad Sci U S A. 2015 Dec 22;112(51):15556-61. doi: 10.1073/pnas.1516779112. Epub 2015 Dec 7.

6.

Matrix metalloproteinase 9-mediated intracerebral hemorrhage induced by cerebral amyloid angiopathy.

Zhao L, Arbel-Ornath M, Wang X, Betensky RA, Greenberg SM, Frosch MP, Bacskai BJ.

Neurobiol Aging. 2015 Nov;36(11):2963-2971. doi: 10.1016/j.neurobiolaging.2015.07.016. Epub 2015 Jul 16.

7.

Abnormal synaptic Ca(2+) homeostasis and morphology in cortical neurons of familial hemiplegic migraine type 1 mutant mice.

Eikermann-Haerter K, Arbel-Ornath M, Yalcin N, Yu ES, Kuchibhotla KV, Yuzawa I, Hudry E, Willard CR, Climov M, Keles F, Belcher AM, Sengul B, Negro A, Rosen IA, Arreguin A, Ferrari MD, van den Maagdenberg AM, Bacskai BJ, Ayata C.

Ann Neurol. 2015 Aug;78(2):193-210. doi: 10.1002/ana.24449. Epub 2015 Jul 6.

8.

Gene transfer of human Apoe isoforms results in differential modulation of amyloid deposition and neurotoxicity in mouse brain.

Hudry E, Dashkoff J, Roe AD, Takeda S, Koffie RM, Hashimoto T, Scheel M, Spires-Jones T, Arbel-Ornath M, Betensky R, Davidson BL, Hyman BT.

Sci Transl Med. 2013 Nov 20;5(212):212ra161. doi: 10.1126/scitranslmed.3007000.

9.

Interstitial fluid drainage is impaired in ischemic stroke and Alzheimer's disease mouse models.

Arbel-Ornath M, Hudry E, Eikermann-Haerter K, Hou S, Gregory JL, Zhao L, Betensky RA, Frosch MP, Greenberg SM, Bacskai BJ.

Acta Neuropathol. 2013 Sep;126(3):353-64. doi: 10.1007/s00401-013-1145-2. Epub 2013 Jul 2.

10.

Reducing available soluble β-amyloid prevents progression of cerebral amyloid angiopathy in transgenic mice.

Gregory JL, Prada CM, Fine SJ, Garcia-Alloza M, Betensky RA, Arbel-Ornath M, Greenberg SM, Bacskai BJ, Frosch MP.

J Neuropathol Exp Neurol. 2012 Nov;71(11):1009-17. doi: 10.1097/NEN.0b013e3182729845.

11.

Inhibition of the NFAT pathway alleviates amyloid β neurotoxicity in a mouse model of Alzheimer's disease.

Hudry E, Wu HY, Arbel-Ornath M, Hashimoto T, Matsouaka R, Fan Z, Spires-Jones TL, Betensky RA, Bacskai BJ, Hyman BT.

J Neurosci. 2012 Feb 29;32(9):3176-92. doi: 10.1523/JNEUROSCI.6439-11.2012.

12.

Immunomodulation of AβPP processing alleviates amyloid-β-related pathology in Alzheimer's disease transgenic mice.

Arbel-Ornath M, Becker M, Rabinovich-Toidman P, Gartner M, Solomon B.

J Alzheimers Dis. 2010;22(2):469-82. doi: 10.3233/JAD-2010-100753.

PMID:
20847413
13.

Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation.

Wu HY, Hudry E, Hashimoto T, Kuchibhotla K, Rozkalne A, Fan Z, Spires-Jones T, Xie H, Arbel-Ornath M, Grosskreutz CL, Bacskai BJ, Hyman BT.

J Neurosci. 2010 Feb 17;30(7):2636-49. doi: 10.1523/JNEUROSCI.4456-09.2010.

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