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Items: 29

1.

Camelid single-domain antibodies raised by DNA immunization are potent inhibitors of EGFR signaling.

Rossotti MA, Henry KA, van Faassen H, Tanha J, Callaghan D, Hussack G, Arbabi-Ghahroudi M, MacKenzie CR.

Biochem J. 2019 Jan 7;476(1):39-50. doi: 10.1042/BCJ20180795.

PMID:
30455372
2.

Camelid Single-Domain Antibodies: Historical Perspective and Future Outlook.

Arbabi-Ghahroudi M.

Front Immunol. 2017 Nov 20;8:1589. doi: 10.3389/fimmu.2017.01589. eCollection 2017.

3.

A Rational Engineering Strategy for Designing Protein A-Binding Camelid Single-Domain Antibodies.

Henry KA, Sulea T, van Faassen H, Hussack G, Purisima EO, MacKenzie CR, Arbabi-Ghahroudi M.

PLoS One. 2016 Sep 15;11(9):e0163113. doi: 10.1371/journal.pone.0163113. eCollection 2016.

4.

Isolation of Camelid Single-Domain Antibodies Against Native Proteins Using Recombinant Multivalent Peptide Ligands.

Alturki NA, Henry KA, MacKenzie CR, Arbabi-Ghahroudi M.

Methods Mol Biol. 2015;1348:167-89. doi: 10.1007/978-1-4939-2999-3_16.

PMID:
26424272
5.

Beyond phage display: non-traditional applications of the filamentous bacteriophage as a vaccine carrier, therapeutic biologic, and bioconjugation scaffold.

Henry KA, Arbabi-Ghahroudi M, Scott JK.

Front Microbiol. 2015 Aug 4;6:755. doi: 10.3389/fmicb.2015.00755. eCollection 2015. Review.

6.

Targeting surface-layer proteins with single-domain antibodies: a potential therapeutic approach against Clostridium difficile-associated disease.

Kandalaft H, Hussack G, Aubry A, van Faassen H, Guan Y, Arbabi-Ghahroudi M, MacKenzie R, Logan SM, Tanha J.

Appl Microbiol Biotechnol. 2015 Oct;99(20):8549-62. doi: 10.1007/s00253-015-6594-1. Epub 2015 May 5.

7.

High affinity anti-Internalin B VHH antibody fragments isolated from naturally and artificially immunized repertoires.

Gene RW, Kumaran J, Aroche C, van Faassen H, Hall JC, MacKenzie CR, Arbabi-Ghahroudi M.

J Immunol Methods. 2015 Jan;416:29-39. doi: 10.1016/j.jim.2014.10.009. Epub 2014 Nov 8.

PMID:
25450000
8.

Protease-resistant single-domain antibodies inhibit Campylobacter jejuni motility.

Hussack G, Riazi A, Ryan S, van Faassen H, MacKenzie R, Tanha J, Arbabi-Ghahroudi M.

Protein Eng Des Sel. 2014 Jun;27(6):191-8. doi: 10.1093/protein/gzu011. Epub 2014 Apr 16.

PMID:
24742504
9.

Single-domain antibodies and their utility.

Baral TN, MacKenzie R, Arbabi Ghahroudi M.

Curr Protoc Immunol. 2013 Nov 18;103:Unit 2.17.. doi: 10.1002/0471142735.im0217s103.

PMID:
24510545
10.

In vivo neutralization of α-cobratoxin with high-affinity llama single-domain antibodies (VHHs) and a VHH-Fc antibody.

Richard G, Meyers AJ, McLean MD, Arbabi-Ghahroudi M, MacKenzie R, Hall JC.

PLoS One. 2013 Jul 22;8(7):e69495. doi: 10.1371/journal.pone.0069495. Print 2013.

11.

Expression of single-domain antibodies in bacterial systems.

Baral TN, Arbabi-Ghahroudi M.

Methods Mol Biol. 2012;911:257-75. doi: 10.1007/978-1-61779-968-6_16.

PMID:
22886257
12.

Isolation and characterization of Clostridium difficile toxin-specific single-domain antibodies.

Hussack G, Arbabi-Ghahroudi M, Mackenzie CR, Tanha J.

Methods Mol Biol. 2012;911:211-39. doi: 10.1007/978-1-61779-968-6_14.

PMID:
22886255
13.

Semiautomated panning of naive camelidae libraries and selection of single-domain antibodies against peptide antigens.

Kumaran J, Mackenzie CR, Arbabi-Ghahroudi M.

Methods Mol Biol. 2012;911:105-24. doi: 10.1007/978-1-61779-968-6_7.

PMID:
22886248
14.

A V(L) single-domain antibody library shows a high-propensity to yield non-aggregating binders.

Hussack G, Keklikian A, Alsughayyir J, Hanifi-Moghaddam P, Arbabi-Ghahroudi M, van Faassen H, Hou ST, Sad S, MacKenzie R, Tanha J.

Protein Eng Des Sel. 2012 Jun;25(6):313-8. doi: 10.1093/protein/gzs014. Epub 2012 Apr 6.

PMID:
22490957
15.

Crystal structure of a human single domain antibody dimer formed through V(H)-V(H) non-covalent interactions.

Baral TN, Chao SY, Li S, Tanha J, Arbabi-Ghahroudi M, Zhang J, Wang S.

PLoS One. 2012;7(1):e30149. doi: 10.1371/journal.pone.0030149. Epub 2012 Jan 12.

16.

Selection and expression of recombinant single domain antibodies from a hyper-immunized library against the hapten azoxystrobin.

Makvandi-Nejad S, Fjällman T, Arbabi-Ghahroudi M, MacKenzie CR, Hall JC.

J Immunol Methods. 2011 Oct 28;373(1-2):8-18. doi: 10.1016/j.jim.2011.07.006. Epub 2011 Jul 18.

PMID:
21777591
17.

Neutralization of Clostridium difficile toxin A with single-domain antibodies targeting the cell receptor binding domain.

Hussack G, Arbabi-Ghahroudi M, van Faassen H, Songer JG, Ng KK, MacKenzie R, Tanha J.

J Biol Chem. 2011 Mar 18;286(11):8961-76. doi: 10.1074/jbc.M110.198754. Epub 2011 Jan 7.

18.

Site-directed mutagenesis for improving biophysical properties of VH domains.

Arbabi-Ghahroudi M, Mackenzie R, Tanha J.

Methods Mol Biol. 2010;634:309-30. doi: 10.1007/978-1-60761-652-8_22.

PMID:
20676993
19.

Intracellular expression of a single domain antibody reduces cytotoxicity of 15-acetyldeoxynivalenol in yeast.

Doyle PJ, Saeed H, Hermans A, Gleddie SC, Hussack G, Arbabi-Ghahroudi M, Seguin C, Savard ME, Mackenzie CR, Hall JC.

J Biol Chem. 2009 Dec 11;284(50):35029-39. doi: 10.1074/jbc.M109.045047. Epub 2009 Sep 25.

20.

Differential tumor-targeting abilities of three single-domain antibody formats.

Bell A, Wang ZJ, Arbabi-Ghahroudi M, Chang TA, Durocher Y, Trojahn U, Baardsnes J, Jaramillo ML, Li S, Baral TN, O'Connor-McCourt M, Mackenzie R, Zhang J.

Cancer Lett. 2010 Mar 1;289(1):81-90. doi: 10.1016/j.canlet.2009.08.003. Epub 2009 Aug 28.

PMID:
19716651
21.

Selection of non-aggregating VH binders from synthetic VH phage-display libraries.

Arbabi-Ghahroudi M, MacKenzie R, Tanha J.

Methods Mol Biol. 2009;525:187-216, xiii. doi: 10.1007/978-1-59745-554-1_10.

PMID:
19252860
22.

Isolation of monoclonal antibody fragments from phage display libraries.

Arbabi-Ghahroudi M, Tanha J, MacKenzie R.

Methods Mol Biol. 2009;502:341-64. doi: 10.1007/978-1-60327-565-1_20.

PMID:
19082566
23.

Aggregation-resistant VHs selected by in vitro evolution tend to have disulfide-bonded loops and acidic isoelectric points.

Arbabi-Ghahroudi M, To R, Gaudette N, Hirama T, Ding W, MacKenzie R, Tanha J.

Protein Eng Des Sel. 2009 Feb;22(2):59-66. doi: 10.1093/protein/gzn071. Epub 2008 Nov 24.

PMID:
19033278
24.

Cloning, expression, and characterization of a single-domain antibody fragment with affinity for 15-acetyl-deoxynivalenol.

Doyle PJ, Arbabi-Ghahroudi M, Gaudette N, Furzer G, Savard ME, Gleddie S, McLean MD, Mackenzie CR, Hall JC.

Mol Immunol. 2008 Aug;45(14):3703-13. doi: 10.1016/j.molimm.2008.06.005. Epub 2008 Jul 15.

PMID:
18632156
25.

Identification of hitherto undefined B-cell epitopes by antibodies in the sera of vitiligo patients using phage-display Peptide library.

Jadali Z, Eslami MB, Sanati MH, Mansoori P, Mahmoudi M, Maghsoodi N, Arbabi Ghahroudi M.

Iran J Allergy Asthma Immunol. 2003 Dec;2(4):197-201.

26.

Prokaryotic expression of antibodies.

Arbabi-Ghahroudi M, Tanha J, MacKenzie R.

Cancer Metastasis Rev. 2005 Dec;24(4):501-19. Review.

PMID:
16408159
27.

Isolation of monomeric human V(H)s by a phage selection.

To R, Hirama T, Arbabi-Ghahroudi M, MacKenzie R, Wang P, Xu P, Ni F, Tanha J.

J Biol Chem. 2005 Dec 16;280(50):41395-403. Epub 2005 Oct 12.

28.

Potent enzyme inhibitors derived from dromedary heavy-chain antibodies.

Lauwereys M, Arbabi Ghahroudi M, Desmyter A, Kinne J, Hölzer W, De Genst E, Wyns L, Muyldermans S.

EMBO J. 1998 Jul 1;17(13):3512-20.

29.

Selection and identification of single domain antibody fragments from camel heavy-chain antibodies.

Arbabi Ghahroudi M, Desmyter A, Wyns L, Hamers R, Muyldermans S.

FEBS Lett. 1997 Sep 15;414(3):521-6.

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