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Items: 12


Multidomain Convergence of Argonaute during RISC Assembly Correlates with the Formation of Internal Water Clusters.

Park MS, Araya-Secchi R, Brackbill JA, Phan HD, Kehling AC, Abd El-Wahab EW, Dayeh DM, Sotomayor M, Nakanishi K.

Mol Cell. 2019 Aug 22;75(4):725-740.e6. doi: 10.1016/j.molcel.2019.06.011. Epub 2019 Jul 16.


A Mechanically Weak Extracellular Membrane-Adjacent Domain Induces Dimerization of Protocadherin-15.

De-la-Torre P, Choudhary D, Araya-Secchi R, Narui Y, Sotomayor M.

Biophys J. 2018 Dec 18;115(12):2368-2385. doi: 10.1016/j.bpj.2018.11.010. Epub 2018 Nov 16.


Beyond Cell-Cell Adhesion: Sensational Cadherins for Hearing and Balance.

Jaiganesh A, Narui Y, Araya-Secchi R, Sotomayor M.

Cold Spring Harb Perspect Biol. 2018 Sep 4;10(9). pii: a029280. doi: 10.1101/cshperspect.a029280. Review.


An elastic element in the protocadherin-15 tip link of the inner ear.

Araya-Secchi R, Neel BL, Sotomayor M.

Nat Commun. 2016 Nov 18;7:13458. doi: 10.1038/ncomms13458.


Exploring the Membrane Potential of Simple Dual-Membrane Systems as Models for Gap-Junction Channels.

Escalona Y, Garate JA, Araya-Secchi R, Huynh T, Zhou R, Perez-Acle T.

Biophys J. 2016 Jun 21;110(12):2678-2688. doi: 10.1016/j.bpj.2016.05.005.


Characterization of a novel water pocket inside the human Cx26 hemichannel structure.

Araya-Secchi R, Perez-Acle T, Kang SG, Huynh T, Bernardin A, Escalona Y, Garate JA, Martínez AD, García IE, Sáez JC, Zhou R.

Biophys J. 2014 Aug 5;107(3):599-612. doi: 10.1016/j.bpj.2014.05.037.


Dual inhibitory pathways of metallofullerenol Gd@C₈₂(OH)₂₂ on matrix metalloproteinase-2: molecular insight into drug-like nanomedicine.

Kang SG, Araya-Secchi R, Wang D, Wang B, Huynh T, Zhou R.

Sci Rep. 2014 Apr 24;4:4775. doi: 10.1038/srep04775.


Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function.

Jara O, Acuña R, García IE, Maripillán J, Figueroa V, Sáez JC, Araya-Secchi R, Lagos CF, Pérez-Acle T, Berthoud VM, Beyer EC, Martínez AD.

Mol Biol Cell. 2012 Sep;23(17):3299-311. Epub 2012 Jul 11.


Molecular dynamics study of the archaeal aquaporin AqpM.

Araya-Secchi R, Garate JA, Holmes DS, Perez-Acle T.

BMC Genomics. 2011 Dec 22;12 Suppl 4:S8. doi: 10.1186/1471-2164-12-S4-S8. Epub 2011 Dec 22.


Molecular modeling of Trypanosoma cruzi glutamate cysteine ligase and investigation of its interactions with glutathione.

Lagos CF, Araya-Secchi R, Thomas P, Pérez-Acle T, Tapia RA, Salas CO.

J Mol Model. 2012 May;18(5):2055-64. doi: 10.1007/s00894-011-1224-z. Epub 2011 Sep 6.


Computational modeling study of functional microdomains in cannabinoid receptor type 1.

Gonzalez A, Duran LS, Araya-Secchi R, Garate JA, Pessoa-Mahana CD, Lagos CF, Perez-Acle T.

Bioorg Med Chem. 2008 Apr 15;16(8):4378-89. doi: 10.1016/j.bmc.2008.02.070. Epub 2008 Feb 26.


An eleven amino acid residue deletion expands the substrate specificity of acetyl xylan esterase II (AXE II) from Penicillium purpurogenum.

Colombres M, Garate JA, Lagos CF, Araya-Secchi R, Norambuena P, Quiroz S, Larrondo L, Pérez-Acle T, Eyzaguirre J.

J Comput Aided Mol Des. 2008 Jan;22(1):19-28. Epub 2007 Dec 1.


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