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Items: 9

1.

Epigenome-wide association study of lung function level and its change.

Imboden M, Wielscher M, Rezwan FI, Amaral AFS, Schaffner E, Jeong A, Beckmeyer-Borowko A, Harris SE, Starr JM, Deary IJ, Flexeder C, Waldenberger M, Peters A, Schulz H, Chen S, Sunny SK, Karmaus WJJ, Jiang Y, Erhart G, Kronenberg F, Arathimos R, Sharp GC, Henderson AJ, Fu Y, Piirilä P, Pietiläinen KH, Ollikainen M, Johansson A, Gyllensten U, de Vries M, van der Plaat DA, de Jong K, Boezen HM, Hall IP, Tobin MD, Jarvelin MR, Holloway JW, Jarvis D, Probst-Hensch NM.

Eur Respir J. 2019 Jul 4;54(1). pii: 1900457. doi: 10.1183/13993003.00457-2019. Print 2019 Jul.

2.

Genetic and observational evidence supports a causal role of sex hormones on the development of asthma.

Arathimos R, Granell R, Haycock P, Richmond RC, Yarmolinsky J, Relton CL, Tilling K.

Thorax. 2019 Jul;74(7):633-642. doi: 10.1136/thoraxjnl-2018-212207. Epub 2019 Apr 1.

3.

Evidence for DNA methylation mediating genetic liability to non-syndromic cleft lip/palate.

Howe LJ, Richardson TG, Arathimos R, Alvizi L, Passos-Bueno MR, Stanier P, Nohr E, Ludwig KU, Mangold E, Knapp M, Stergiakouli E, Pourcain BS, Smith GD, Sandy J, Relton CL, Lewis SJ, Hemani G, Sharp GC.

Epigenomics. 2019 Feb;11(2):133-145. doi: 10.2217/epi-2018-0091. Epub 2019 Jan 14.

4.

Epigenome-wide meta-analysis of DNA methylation and childhood asthma.

Reese SE, Xu CJ, den Dekker HT, Lee MK, Sikdar S, Ruiz-Arenas C, Merid SK, Rezwan FI, Page CM, Ullemar V, Melton PE, Oh SS, Yang IV, Burrows K, Söderhäll C, Jima DD, Gao L, Arathimos R, Küpers LK, Wielscher M, Rzehak P, Lahti J, Laprise C, Madore AM, Ward J, Bennett BD, Wang T, Bell DA; BIOS consortium, Vonk JM, Håberg SE, Zhao S, Karlsson R, Hollams E, Hu D, Richards AJ, Bergström A, Sharp GC, Felix JF, Bustamante M, Gruzieva O, Maguire RL, Gilliland F, Baïz N, Nohr EA, Corpeleijn E, Sebert S, Karmaus W, Grote V, Kajantie E, Magnus MC, Örtqvist AK, Eng C, Liu AH, Kull I, Jaddoe VWV, Sunyer J, Kere J, Hoyo C, Annesi-Maesano I, Arshad SH, Koletzko B, Brunekreef B, Binder EB, Räikkönen K, Reischl E, Holloway JW, Jarvelin MR, Snieder H, Kazmi N, Breton CV, Murphy SK, Pershagen G, Anto JM, Relton CL, Schwartz DA, Burchard EG, Huang RC, Nystad W, Almqvist C, Henderson AJ, Melén E, Duijts L, Koppelman GH, London SJ.

J Allergy Clin Immunol. 2019 Jun;143(6):2062-2074. doi: 10.1016/j.jaci.2018.11.043. Epub 2018 Dec 21.

5.

Associations of sex hormone-binding globulin and testosterone with genome-wide DNA methylation.

Arathimos R, Sharp GC, Granell R, Tilling K, Relton CL.

BMC Genet. 2018 Dec 14;19(1):113. doi: 10.1186/s12863-018-0703-y.

6.

SERPINA1 methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based cohorts.

Beckmeyer-Borowko A, Imboden M, Rezwan FI, Wielscher M, Amaral AFS, Jeong A, Schaffner E, Auvinen J, Sebert S, Karhunen V, Bettschart R, Turk A, Pons M, Stolz D, Kronenberg F, Arathimos R, Sharp GC, Relton C, Henderson AJ, Jarvelin MR, Jarvis D, Holloway JW, Probst-Hensch NM.

Respir Res. 2018 Aug 22;19(1):156. doi: 10.1186/s12931-018-0850-8.

7.

Maternal alcohol consumption and offspring DNA methylation: findings from six general population-based birth cohorts.

Sharp GC, Arathimos R, Reese SE, Page CM, Felix J, Küpers LK, Rifas-Shiman SL, Liu C; Cohorts for Heart and Aging Research in Genomic Epidemiology plus (CHARGE +) methylation alcohol working group, Burrows K, Zhao S, Magnus MC, Duijts L, Corpeleijn E, DeMeo DL, Litonjua A, Baccarelli A, Hivert MF, Oken E, Snieder H, Jaddoe V, Nystad W, London SJ, Relton CL, Zuccolo L.

Epigenomics. 2018 Jan;10(1):27-42. doi: 10.2217/epi-2017-0095. Epub 2017 Nov 27.

8.

Epigenome-wide association study of asthma and wheeze in childhood and adolescence.

Arathimos R, Suderman M, Sharp GC, Burrows K, Granell R, Tilling K, Gaunt TR, Henderson J, Ring S, Richmond RC, Relton CL.

Clin Epigenetics. 2017 Oct 13;9:112. doi: 10.1186/s13148-017-0414-7. eCollection 2017.

9.

Sex discordance in asthma and wheeze prevalence in two longitudinal cohorts.

Arathimos R, Granell R, Henderson J, Relton CL, Tilling K.

PLoS One. 2017 Apr 25;12(4):e0176293. doi: 10.1371/journal.pone.0176293. eCollection 2017.

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