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Items: 1 to 50 of 117

1.

A molecular mechanism underlying genotype-specific intrahepatic cholestasis resulting from MYO5B mutations.

Overeem AW, Li Q, Qiu YL, Carton-Garciá F, Leng C, Klappe K, Dronkers J, Hsiao NH, Wang JS, Arango D, van IJzendoorn SCD.

Hepatology. 2019 Nov 21. doi: 10.1002/hep.31002. [Epub ahead of print]

PMID:
31750554
2.

Loss of MYO5B expression deregulates late endosome size which hinders mitotic spindle orientation.

Leng C, Overeem AW, Cartón-Garcia F, Li Q, Klappe K, Kuipers J, Cui Y, Zuhorn IS, Arango D, van IJzendoorn SCD.

PLoS Biol. 2019 Nov 4;17(11):e3000531. doi: 10.1371/journal.pbio.3000531. eCollection 2019 Nov.

3.

Zileuton™ loaded in polymer micelles effectively reduce breast cancer circulating tumor cells and intratumoral cancer stem cells.

Gener P, Montero S, Xandri-Monje H, Díaz-Riascos ZV, Rafael D, Andrade F, Martínez-Trucharte F, González P, Seras-Franzoso J, Manzano A, Arango D, Sayós J, Abasolo I, Schwartz S Jr.

Nanomedicine. 2019 Oct 27;24:102106. doi: 10.1016/j.nano.2019.102106. [Epub ahead of print]

4.

Glucocorticoids and myosin5b loss of function induce heightened PKA signaling in addition to membrane traffic defects.

Forteza R, Ahsan MK, Cartón-García F, Arango D, Ameen NA, Salas PJ.

Mol Biol Cell. 2019 Dec 15;30(26):3076-3089. doi: 10.1091/mbc.E18-07-0415. Epub 2019 Oct 30.

PMID:
31664880
5.

Tumor Expression of Cyclin-Dependent Kinase 5 (Cdk5) Is a Prognostic Biomarker and Predicts Outcome of Oxaliplatin-Treated Metastatic Colorectal Cancer Patients.

Ruiz de Porras V, Bystrup S, Cabrero-de Las Heras S, Musulén E, Palomero L, Alonso MH, Nieto R, Arango D, Moreno V, Queralt C, Manzano JL, Layos L, Bugés C, Martinez-Balibrea E.

Cancers (Basel). 2019 Oct 11;11(10). pii: E1540. doi: 10.3390/cancers11101540.

6.

Serosurveillance for vaccine-preventable diseases: A look inside the pertussis experience

Hincapié D, Acevedo M, Hoyos MC, Ochoa J, González C, Pérez PA, Molina A, Restrepo BI, Arrubla M, Echeverri AP, Almanza RE, González LD, Santacruz-Sanmartín E, Orrego NE, Arango D, Gutiérrez AM, Londoño OL, Toro LM, Ríos M, Villada O, Mejía LA, Arenas PA, García D, Osorio E.

Biomedica. 2019 Aug 1;39(Supl. 2):130-143. doi: 10.7705/biomedica.v39i4.4181. English, Spanish.

7.

Pivotal Role of AKT2 during Dynamic Phenotypic Change of Breast Cancer Stem Cells.

Gener P, Rafael D, Seras-Franzoso J, Perez A, Pindado LA, Casas G, Arango D, Fernández Y, Díaz-Riascos ZV, Abasolo I, Schwartz S Jr.

Cancers (Basel). 2019 Jul 26;11(8). pii: E1058. doi: 10.3390/cancers11081058.

8.

Nanotechnology is an important strategy for combinational innovative chemo-immunotherapies against colorectal cancer.

Matos AI, Carreira B, Peres C, Moura LIF, Conniot J, Fourniols T, Scomparin A, Martínez-Barriocanal Á, Arango D, Conde JP, Préat V, Satchi-Fainaro R, Florindo HF.

J Control Release. 2019 Aug 10;307:108-138. doi: 10.1016/j.jconrel.2019.06.017. Epub 2019 Jun 19. Review.

PMID:
31226355
9.

Artemisinin-based combination therapy during pregnancy: outcome of pregnancy and infant mortality: a cohort study.

Nambozi M, Tinto H, Mwapasa V, Tagbor H, Kabuya JB, Hachizovu S, Traoré M, Valea I, Tahita MC, Ampofo G, Buyze J, Ravinetto R, Arango D, Thriemer K, Mulenga M, van Geertruyden JP, D'Alessandro U.

Malar J. 2019 Mar 28;18(1):105. doi: 10.1186/s12936-019-2737-7.

10.

Effect of intrasite vancomycin powder on development of epidural fibrosis.

Clippinger B, Ayzenberg M, Narvaez M, Arango D, Minimo C, Pahys J, Handal J.

Orthop Rev (Pavia). 2018 Dec 6;10(4):7777. doi: 10.4081/or.2018.7777. eCollection 2018 Dec 6.

11.

Acetylation of Cytidine in mRNA Promotes Translation Efficiency.

Arango D, Sturgill D, Alhusaini N, Dillman AA, Sweet TJ, Hanson G, Hosogane M, Sinclair WR, Nanan KK, Mandler MD, Fox SD, Zengeya TT, Andresson T, Meier JL, Coller J, Oberdoerffer S.

Cell. 2018 Dec 13;175(7):1872-1886.e24. doi: 10.1016/j.cell.2018.10.030. Epub 2018 Nov 15.

12.

Dynamism, Sensitivity, and Consequences of Mesenchymal and Stem-Like Phenotype of Cancer Cells.

Gener P, Seras-Franzoso J, Callejo PG, Andrade F, Rafael D, Martínez F, Montero S, Arango D, Sayós J, Abasolo I, Schwartz S Jr.

Stem Cells Int. 2018 Oct 10;2018:4516454. doi: 10.1155/2018/4516454. eCollection 2018. Review.

13.

A Chemical Signature for Cytidine Acetylation in RNA.

Thomas JM, Briney CA, Nance KD, Lopez JE, Thorpe AL, Fox SD, Bortolin-Cavaille ML, Sas-Chen A, Arango D, Oberdoerffer S, Cavaille J, Andresson T, Meier JL.

J Am Chem Soc. 2018 Oct 10;140(40):12667-12670. doi: 10.1021/jacs.8b06636. Epub 2018 Sep 25.

PMID:
30252461
14.

Validation of the Oswestry Risk of Knee Arthroplasty Index (ORKA-1) for Patients Undergoing Autologous Chondrocyte Implantation.

Ackermann J, Barbieri Mestriner A, Arango D, Ogura T, Gomoll AH.

Cartilage. 2018 Aug 27:1947603518796146. doi: 10.1177/1947603518796146. [Epub ahead of print]

PMID:
30146892
15.

Silencing of adaptor protein SH3BP2 reduces KIT/PDGFRA receptors expression and impairs gastrointestinal stromal tumors growth.

Serrano-Candelas E, Ainsua-Enrich E, Navinés-Ferrer A, Rodrigues P, García-Valverde A, Bazzocco S, Macaya I, Arribas J, Serrano C, Sayós J, Arango D, Martin M.

Mol Oncol. 2018 Aug;12(8):1383-1397. doi: 10.1002/1878-0261.12332. Epub 2018 Jun 30.

16.

AKT2 siRNA delivery with amphiphilic-based polymeric micelles show efficacy against cancer stem cells.

Rafael D, Gener P, Andrade F, Seras-Franzoso J, Montero S, Fernández Y, Hidalgo M, Arango D, Sayós J, Florindo HF, Abasolo I, Schwartz S Jr, Videira M.

Drug Deliv. 2018 Nov;25(1):961-972. doi: 10.1080/10717544.2018.1461276.

17.

DUSP5 is methylated in CIMP-high colorectal cancer but is not a major regulator of intestinal cell proliferation and tumorigenesis.

Tögel L, Nightingale R, Wu R, Chüeh AC, Al-Obaidi S, Luk I, Dávalos-Salas M, Chionh F, Murone C, Buchanan DD, Chatterton Z, Sieber OM, Arango D, Tebbutt NC, Williams D, Dhillon AS, Mariadason JM.

Sci Rep. 2018 Jan 29;8(1):1767. doi: 10.1038/s41598-018-20176-9.

18.

Mechanisms of inactivation of the tumour suppressor gene RHOA in colorectal cancer.

Dopeso H, Rodrigues P, Bilic J, Bazzocco S, Cartón-García F, Macaya I, de Marcondes PG, Anguita E, Masanas M, Jiménez-Flores LM, Martínez-Barriocanal Á, Nieto R, Segura MF, Schwartz S Jr, Mariadason JM, Arango D.

Br J Cancer. 2018 Jan;118(1):106-116. doi: 10.1038/bjc.2017.420. Epub 2017 Dec 5.

19.

Biomechanical analysis of four external fixation pin insertion techniques.

Arango D, Tiedeken N, Clippinger B, Samuel SP, Saldanha V, Shaffer G.

Orthop Rev (Pavia). 2017 Oct 3;9(3):7067. doi: 10.4081/or.2017.7067. eCollection 2017 Sep 30. Review. No abstract available.

20.

Profiling Cytidine Acetylation with Specific Affinity and Reactivity.

Sinclair WR, Arango D, Shrimp JH, Zengeya TT, Thomas JM, Montgomery DC, Fox SD, Andresson T, Oberdoerffer S, Meier JL.

ACS Chem Biol. 2017 Dec 15;12(12):2922-2926. doi: 10.1021/acschembio.7b00734. Epub 2017 Oct 17.

PMID:
29039931
21.

Acute Both Bone Fracture in a Chronic Contracted Forearm.

Ayzenberg M, Tiedeken NC, Arango DE, Raphael J.

J Orthop Case Rep. 2016 Nov-Dec;6(5):55-58. doi: 10.13107/jocr.2250-0685.630.

22.

Mortality in traffic accidents with older adults in Colombia.

Cardona AM, Arango DC, Fernández DY, Martínez AA.

Rev Saude Publica. 2017;51:21. doi: 10.1590/s1518-8787.2017051006405. Epub 2017 Mar 27. Spanish, English.

23.

Loss of the EPH receptor B6 contributes to colorectal cancer metastasis.

Mateo-Lozano S, Bazzocco S, Rodrigues P, Mazzolini R, Andretta E, Dopeso H, Fernández Y, Del Llano E, Bilic J, Suárez-López L, Macaya I, Cartón-García F, Nieto R, Jimenez-Flores LM, de Marcondes PG, Nuñez Y, Afonso E, Cacci K, Hernández-Losa J, Landolfi S, Abasolo I, Ramón Y Cajal S, Mariadason JM, Schwartz S Jr, Matsui T, Arango D.

Sci Rep. 2017 Mar 6;7:43702. doi: 10.1038/srep43702.

24.

Pullout strength of a novel hybrid fixation technique (Tape Locking Screw™) in soft-tissue ACL reconstruction: A biomechanical study in human and porcine bone.

Ayzenberg M, Arango D, Gershkovich GE, Samuel PS, Saing M.

Orthop Traumatol Surg Res. 2017 Jun;103(4):591-595. doi: 10.1016/j.otsr.2017.01.006. Epub 2017 Feb 24.

25.

Investigation of the role of tyrosine kinase receptor EPHA3 in colorectal cancer.

Andretta E, Cartón-García F, Martínez-Barriocanal Á, de Marcondes PG, Jimenez-Flores LM, Macaya I, Bazzocco S, Bilic J, Rodrigues P, Nieto R, Landolfi S, Ramon Y Cajal S, Schwartz S, Brown A, Dopeso H, Arango D.

Sci Rep. 2017 Feb 7;7:41576. doi: 10.1038/srep41576.

26.

Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells.

Tögel L, Nightingale R, Chueh AC, Jayachandran A, Tran H, Phesse T, Wu R, Sieber OM, Arango D, Dhillon AS, Dawson MA, Diez-Dacal B, Gahman TC, Filippakopoulos P, Shiau AK, Mariadason JM.

Mol Cancer Ther. 2016 Jun;15(6):1217-26. doi: 10.1158/1535-7163.MCT-15-0724. Epub 2016 Mar 16.

27.

Dietary Apigenin Exerts Immune-Regulatory Activity in Vivo by Reducing NF-κB Activity, Halting Leukocyte Infiltration and Restoring Normal Metabolic Function.

Cardenas H, Arango D, Nicholas C, Duarte S, Nuovo GJ, He W, Voss OH, Gonzalez-Mejia ME, Guttridge DC, Grotewold E, Doseff AI.

Int J Mol Sci. 2016 Mar 1;17(3):323. doi: 10.3390/ijms17030323.

28.

Cancer stem cells and personalized cancer nanomedicine.

Gener P, Rafael DF, Fernández Y, Ortega JS, Arango D, Abasolo I, Videira M, Schwartz S Jr.

Nanomedicine (Lond). 2016 Feb;11(3):307-20. doi: 10.2217/nnm.15.200. Epub 2016 Jan 20. Review.

PMID:
26785724
29.

Bilateral Hemiarthroplasty in a Patient with Below-Knee and Above-Knee Amputations: A Case Report.

Arango D, Tiedeken NC, Gershkovich G, Shaffer G.

JBJS Case Connect. 2016 Jan-Mar;6(1):e3. doi: 10.2106/JBJS.CC.O.00114.

PMID:
29252713
30.

Fluorescent CSC models evidence that targeted nanomedicines improve treatment sensitivity of breast and colon cancer stem cells.

Gener P, Gouveia LP, Sabat GR, de Sousa Rafael DF, Fort NB, Arranja A, Fernández Y, Prieto RM, Ortega JS, Arango D, Abasolo I, Videira M, Schwartz S Jr.

Nanomedicine. 2015 Nov;11(8):1883-92. doi: 10.1016/j.nano.2015.07.009. Epub 2015 Jul 31.

PMID:
26238079
31.

Myo5b knockout mice as a model of microvillus inclusion disease.

Cartón-García F, Overeem AW, Nieto R, Bazzocco S, Dopeso H, Macaya I, Bilic J, Landolfi S, Hernandez-Losa J, Schwartz S Jr, Ramon y Cajal S, van Ijzendoorn SC, Arango D.

Sci Rep. 2015 Jul 23;5:12312. doi: 10.1038/srep12312.

32.

The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner.

Shin J, Carr A, Corner GA, Tögel L, Dávalos-Salas M, Tran H, Chueh AC, Al-Obaidi S, Chionh F, Ahmed N, Buchanan DD, Young JP, Malo MS, Hodin RA, Arango D, Sieber OM, Augenlicht LH, Dhillon AS, Weber TK, Mariadason JM.

J Biol Chem. 2015 Jun 19;290(25):15392. doi: 10.1074/jbc.A114.557546. No abstract available.

33.

Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment.

Bazzocco S, Dopeso H, Carton-Garcia F, Macaya I, Andretta E, Chionh F, Rodrigues P, Garrido M, Alazzouzi H, Nieto R, Sanchez A, Schwartz S Jr, Bilic J, Mariadason JM, Arango D.

Clin Cancer Res. 2015 Aug 15;21(16):3695-704. doi: 10.1158/1078-0432.CCR-14-2457. Epub 2015 May 5.

34.

PTPRD is homozygously deleted and epigenetically downregulated in human hepatocellular carcinomas.

Acun T, Demir K, Oztas E, Arango D, Yakicier MC.

OMICS. 2015 Apr;19(4):220-9. doi: 10.1089/omi.2015.0010.

PMID:
25831062
35.

Dietary apigenin reduces LPS-induced expression of miR-155 restoring immune balance during inflammation.

Arango D, Diosa-Toro M, Rojas-Hernandez LS, Cooperstone JL, Schwartz SJ, Mo X, Jiang J, Schmittgen TD, Doseff AI.

Mol Nutr Food Res. 2015 Apr;59(4):763-72. doi: 10.1002/mnfr.201400705. Epub 2015 Feb 23.

PMID:
25641956
36.

Prevention of violence against women and girls: what does the evidence say?

Ellsberg M, Arango DJ, Morton M, Gennari F, Kiplesund S, Contreras M, Watts C.

Lancet. 2015 Apr 18;385(9977):1555-66. doi: 10.1016/S0140-6736(14)61703-7. Epub 2014 Nov 21. Review.

PMID:
25467575
37.

RHOA inactivation enhances Wnt signalling and promotes colorectal cancer.

Rodrigues P, Macaya I, Bazzocco S, Mazzolini R, Andretta E, Dopeso H, Mateo-Lozano S, Bilić J, Cartón-García F, Nieto R, Suárez-López L, Afonso E, Landolfi S, Hernandez-Losa J, Kobayashi K, Ramón y Cajal S, Tabernero J, Tebbutt NC, Mariadason JM, Schwartz S Jr, Arango D.

Nat Commun. 2014 Nov 21;5:5458. doi: 10.1038/ncomms6458.

38.

The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner.

Shin J, Carr A, Corner GA, Tögel L, Dávalos-Salas M, Tran H, Chueh AC, Al-Obaidi S, Chionh F, Ahmed N, Buchanan DD, Young JP, Malo MS, Hodin RA, Arango D, Sieber OM, Augenlicht LH, Dhillon AS, Weber TK, Mariadason JM.

J Biol Chem. 2014 Sep 5;289(36):25306-16. doi: 10.1074/jbc.M114.557546. Epub 2014 Jul 18. Erratum in: J Biol Chem. 2015 Jun 19;290(25):15392. Dávaos-Salas, Mercedes [Corrected to Dávalos-Salas, Mercedes].

39.

Open perilunate injury with lunate revascularization after complete ligamentous avulsion.

Arango D, Tiedeken NC, Ayzenberg M, Raphael J.

J Surg Case Rep. 2014 May 12;2014(5). pii: rju041. doi: 10.1093/jscr/rju041.

40.

Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.

Mouradov D, Sloggett C, Jorissen RN, Love CG, Li S, Burgess AW, Arango D, Strausberg RL, Buchanan D, Wormald S, O'Connor L, Wilding JL, Bicknell D, Tomlinson IP, Bodmer WF, Mariadason JM, Sieber OM.

Cancer Res. 2014 Jun 15;74(12):3238-47. doi: 10.1158/0008-5472.CAN-14-0013. Epub 2014 Apr 22.

41.

Apigenin protects endothelial cells from lipopolysaccharide (LPS)-induced inflammation by decreasing caspase-3 activation and modulating mitochondrial function.

Duarte S, Arango D, Parihar A, Hamel P, Yasmeen R, Doseff AI.

Int J Mol Sci. 2013 Aug 28;14(9):17664-79. doi: 10.3390/ijms140917664.

42.

National access to care for children with fractures.

Iobst C, Arango D, Segal D, Skaggs DL.

J Pediatr Orthop. 2013 Sep;33(6):587-91. doi: 10.1097/BPO.0b013e31829b2da4.

PMID:
23812144
43.

Molecular basis for the action of a dietary flavonoid revealed by the comprehensive identification of apigenin human targets.

Arango D, Morohashi K, Yilmaz A, Kuramochi K, Parihar A, Brahimaj B, Grotewold E, Doseff AI.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):E2153-62. doi: 10.1073/pnas.1303726110. Epub 2013 May 22.

44.

Two-year outcome with the AperFix system for ACL reconstruction.

Uribe JW, Arango D, Frank J, Kiebzak GM.

Orthopedics. 2013 Feb;36(2):e159-64. doi: 10.3928/01477447-20130122-17.

PMID:
23379927
45.

Selected anatomists: at the boundary of contemporary ethics.

Arango D, Greiffenstein P, O'Leary JP.

JAMA Surg. 2013 Jan;148(1):94-8. doi: 10.1001/jamasurgery.2013.407.

PMID:
23324845
46.

Human SMC2 protein, a core subunit of human condensin complex, is a novel transcriptional target of the WNT signaling pathway and a new therapeutic target.

Dávalos V, Súarez-López L, Castaño J, Messent A, Abasolo I, Fernandez Y, Guerra-Moreno A, Espín E, Armengol M, Musulen E, Ariza A, Sayós J, Arango D, Schwartz S Jr.

J Biol Chem. 2012 Dec 21;287(52):43472-81. doi: 10.1074/jbc.M112.428466. Epub 2012 Oct 24.

47.

Brush border myosin Ia inactivation in gastric but not endometrial tumors.

Mazzolini R, Rodrigues P, Bazzocco S, Dopeso H, Ferreira AM, Mateo-Lozano S, Andretta E, Woerner SM, Alazzouzi H, Landolfi S, Hernandez-Losa J, Macaya I, Suzuki H, Ramón y Cajal S, Mooseker MS, Mariadason JM, Gebert J, Hofstra RM, Reventós J, Yamamoto H, Schwartz S Jr, Arango D.

Int J Cancer. 2013 Apr 15;132(8):1790-9. doi: 10.1002/ijc.27856. Epub 2012 Oct 20.

48.

Apigenin induces DNA damage through the PKCδ-dependent activation of ATM and H2AX causing down-regulation of genes involved in cell cycle control and DNA repair.

Arango D, Parihar A, Villamena FA, Wang L, Freitas MA, Grotewold E, Doseff AI.

Biochem Pharmacol. 2012 Dec 15;84(12):1571-80. doi: 10.1016/j.bcp.2012.09.005. Epub 2012 Sep 14.

49.

High-throughput screening of transglutaminase activity using plasmonic fluorescent nanocomposites.

Achyuthan KE, Allen A, Arango DC, Harper JC, Brozik SM.

Anal Sci. 2012;28(9):905-10.

50.

Rational redesign of glucose oxidase for improved catalytic function and stability.

Holland JT, Harper JC, Dolan PL, Manginell MM, Arango DC, Rawlings JA, Apblett CA, Brozik SM.

PLoS One. 2012;7(6):e37924. doi: 10.1371/journal.pone.0037924. Epub 2012 Jun 13.

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