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A Second RNA-Binding Site in the NS1 Protein of Influenza B Virus.

Ma LC, Guan R, Hamilton K, Aramini JM, Mao L, Wang S, Krug RM, Montelione GT.

Structure. 2016 Sep 6;24(9):1562-72. doi: 10.1016/j.str.2016.07.001. Epub 2016 Aug 18.


Recombinant expression, antimicrobial activity and mechanism of action of tritrpticin analogs containing fluoro-tryptophan residues.

Arias M, Hoffarth ER, Ishida H, Aramini JM, Vogel HJ.

Biochim Biophys Acta. 2016 May;1858(5):1012-23. doi: 10.1016/j.bbamem.2015.12.023. Epub 2015 Dec 23.


A community resource of experimental data for NMR / X-ray crystal structure pairs.

Everett JK, Tejero R, Murthy SB, Acton TB, Aramini JM, Baran MC, Benach J, Cort JR, Eletsky A, Forouhar F, Guan R, Kuzin AP, Lee HW, Liu G, Mani R, Mao B, Mills JL, Montelione AF, Pederson K, Powers R, Ramelot T, Rossi P, Seetharaman J, Snyder D, Swapna GV, Vorobiev SM, Wu Y, Xiao R, Yang Y, Arrowsmith CH, Hunt JF, Kennedy MA, Prestegard JH, Szyperski T, Tong L, Montelione GT.

Protein Sci. 2016 Jan;25(1):30-45. doi: 10.1002/pro.2774. Epub 2015 Sep 22. Review.


The RAS-Binding Domain of Human BRAF Protein Serine/Threonine Kinase Exhibits Allosteric Conformational Changes upon Binding HRAS.

Aramini JM, Vorobiev SM, Tuberty LM, Janjua H, Campbell ET, Seetharaman J, Su M, Huang YJ, Acton TB, Xiao R, Tong L, Montelione GT.

Structure. 2015 Aug 4;23(8):1382-1393. doi: 10.1016/j.str.2015.06.003. Epub 2015 Jul 9.


Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction.

Aiyer S, Swapna GV, Malani N, Aramini JM, Schneider WM, Plumb MR, Ghanem M, Larue RC, Sharma A, Studamire B, Kvaratskhelia M, Bushman FD, Montelione GT, Roth MJ.

Nucleic Acids Res. 2014 May;42(9):5917-28. doi: 10.1093/nar/gku175. Epub 2014 Mar 12.


(19)F NMR reveals multiple conformations at the dimer interface of the nonstructural protein 1 effector domain from influenza A virus.

Aramini JM, Hamilton K, Ma LC, Swapna GVT, Leonard PG, Ladbury JE, Krug RM, Montelione GT.

Structure. 2014 Apr 8;22(4):515-525. doi: 10.1016/j.str.2014.01.010. Epub 2014 Feb 27.


Assessment of template-based protein structure predictions in CASP10.

Huang YJ, Mao B, Aramini JM, Montelione GT.

Proteins. 2014 Feb;82 Suppl 2:43-56. doi: 10.1002/prot.24488.


PDBStat: a universal restraint converter and restraint analysis software package for protein NMR.

Tejero R, Snyder D, Mao B, Aramini JM, Montelione GT.

J Biomol NMR. 2013 Aug;56(4):337-51. doi: 10.1007/s10858-013-9753-7. Epub 2013 Jul 30.


Structures of apo- and ssDNA-bound YdbC from Lactococcus lactis uncover the function of protein domain family DUF2128 and expand the single-stranded DNA-binding domain proteome.

Rossi P, Barbieri CM, Aramini JM, Bini E, Lee HW, Janjua H, Xiao R, Acton TB, Montelione GT.

Nucleic Acids Res. 2013 Feb 1;41(4):2756-68. doi: 10.1093/nar/gks1348. Epub 2013 Jan 8.


Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples.

Lange OF, Rossi P, Sgourakis NG, Song Y, Lee HW, Aramini JM, Ertekin A, Xiao R, Acton TB, Montelione GT, Baker D.

Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10873-8. doi: 10.1073/pnas.1203013109. Epub 2012 Jun 25.


Solution NMR structure of Alr2454 from Nostoc sp. PCC 7120, the first structural representative of Pfam domain family PF11267.

Aramini JM, Petrey D, Lee DY, Janjua H, Xiao R, Acton TB, Everett JK, Montelione GT.

J Struct Funct Genomics. 2012 Sep;13(3):171-6. doi: 10.1007/s10969-012-9135-5. Epub 2012 May 17.


Solution NMR structure, backbone dynamics, and heme-binding properties of a novel cytochrome c maturation protein CcmE from Desulfovibrio vulgaris.

Aramini JM, Hamilton K, Rossi P, Ertekin A, Lee HW, Lemak A, Wang H, Xiao R, Acton TB, Everett JK, Montelione GT.

Biochemistry. 2012 May 8;51(18):3705-7. doi: 10.1021/bi300457b. Epub 2012 Apr 24.


Human cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered N-terminal region.

Ertekin A, Aramini JM, Rossi P, Leonard PG, Janjua H, Xiao R, Maglaqui M, Lee HW, Prestegard JH, Montelione GT.

J Biol Chem. 2012 May 11;287(20):16541-9. doi: 10.1074/jbc.M112.343863. Epub 2012 Mar 14.


Solution NMR structure of the ribosomal protein RP-L35Ae from Pyrococcus furiosus.

Snyder DA, Aramini JM, Yu B, Huang YJ, Xiao R, Cort JR, Shastry R, Ma LC, Liu J, Rost B, Acton TB, Kennedy MA, Montelione GT.

Proteins. 2012 Jul;80(7):1901-6. doi: 10.1002/prot.24071. Epub 2012 Apr 16.


Blind testing of routine, fully automated determination of protein structures from NMR data.

Rosato A, Aramini JM, Arrowsmith C, Bagaria A, Baker D, Cavalli A, Doreleijers JF, Eletsky A, Giachetti A, Guerry P, Gutmanas A, Güntert P, He Y, Herrmann T, Huang YJ, Jaravine V, Jonker HR, Kennedy MA, Lange OF, Liu G, Malliavin TE, Mani R, Mao B, Montelione GT, Nilges M, Rossi P, van der Schot G, Schwalbe H, Szyperski TA, Vendruscolo M, Vernon R, Vranken WF, Vries Sd, Vuister GW, Wu B, Yang Y, Bonvin AM.

Structure. 2012 Feb 8;20(2):227-36. doi: 10.1016/j.str.2012.01.002.


Solution NMR structure of VF0530 from Vibrio fischeri reveals a nucleic acid-binding function.

Aramini JM, Rossi P, Fischer M, Xiao R, Acton TB, Montelione GT.

Proteins. 2011 Oct;79(10):2988-91. doi: 10.1002/prot.23121. Epub 2011 Aug 26.


Dimer interface of the effector domain of non-structural protein 1 from influenza A virus: an interface with multiple functions.

Aramini JM, Ma LC, Zhou L, Schauder CM, Hamilton K, Amer BR, Mack TR, Lee HW, Ciccosanti CT, Zhao L, Xiao R, Krug RM, Montelione GT.

J Biol Chem. 2011 Jul 22;286(29):26050-60. doi: 10.1074/jbc.M111.248765. Epub 2011 May 26.


Backbone and Ile-δ1, Leu, Val methyl 1H, 13C and 15N NMR chemical shift assignments for human interferon-stimulated gene 15 protein.

Yin C, Aramini JM, Ma LC, Cort JR, Swapna GV, Krug RM, Montelione GT.

Biomol NMR Assign. 2011 Oct;5(2):215-9. doi: 10.1007/s12104-011-9303-8. Epub 2011 May 5.


Solution NMR structure of the plasmid-encoded fimbriae regulatory protein PefI from Salmonella enterica serovar Typhimurium.

Aramini JM, Rossi P, Cort JR, Ma LC, Xiao R, Acton TB, Montelione GT.

Proteins. 2011 Jan;79(1):335-9. doi: 10.1002/prot.22869. No abstract available.


Structures of influenza A proteins and insights into antiviral drug targets.

Das K, Aramini JM, Ma LC, Krug RM, Arnold E.

Nat Struct Mol Biol. 2010 May;17(5):530-8. doi: 10.1038/nsmb.1779. Epub 2010 Apr 11. Review.


Structural basis of O6-alkylguanine recognition by a bacterial alkyltransferase-like DNA repair protein.

Aramini JM, Tubbs JL, Kanugula S, Rossi P, Ertekin A, Maglaqui M, Hamilton K, Ciccosanti CT, Jiang M, Xiao R, Soong TT, Rost B, Acton TB, Everett JK, Pegg AE, Tainer JA, Montelione GT.

J Biol Chem. 2010 Apr 30;285(18):13736-41. doi: 10.1074/jbc.M109.093591. Epub 2010 Mar 8.


Accurate automated protein NMR structure determination using unassigned NOESY data.

Raman S, Huang YJ, Mao B, Rossi P, Aramini JM, Liu G, Montelione GT, Baker D.

J Am Chem Soc. 2010 Jan 13;132(1):202-7. doi: 10.1021/ja905934c.


A microscale protein NMR sample screening pipeline.

Rossi P, Swapna GV, Huang YJ, Aramini JM, Anklin C, Conover K, Hamilton K, Xiao R, Acton TB, Ertekin A, Everett JK, Montelione GT.

J Biomol NMR. 2010 Jan;46(1):11-22. doi: 10.1007/s10858-009-9386-z. Epub 2009 Nov 14.


Emerging antiviral targets for influenza A virus.

Krug RM, Aramini JM.

Trends Pharmacol Sci. 2009 Jun;30(6):269-77. doi: 10.1016/ Epub 2009 May 8. Review.


Construct optimization for protein NMR structure analysis using amide hydrogen/deuterium exchange mass spectrometry.

Sharma S, Zheng H, Huang YJ, Ertekin A, Hamuro Y, Rossi P, Tejero R, Acton TB, Xiao R, Jiang M, Zhao L, Ma LC, Swapna GV, Aramini JM, Montelione GT.

Proteins. 2009 Sep;76(4):882-94. doi: 10.1002/prot.22394.


NMR and X-RAY structures of human E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1) reveal structural and functional conservation in the metazoan UFM1-UBA5-UFC1 ubiquination pathway.

Liu G, Forouhar F, Eletsky A, Atreya HS, Aramini JM, Xiao R, Huang YJ, Abashidze M, Seetharaman J, Liu J, Rost B, Acton T, Montelione GT, Hunt JF, Szyperski T.

J Struct Funct Genomics. 2009 Apr;10(2):127-36. doi: 10.1007/s10969-008-9054-7. Epub 2008 Dec 20.


Structural elucidation of the Cys-His-Glu-Asn proteolytic relay in the secreted CHAP domain enzyme from the human pathogen Staphylococcus saprophyticus.

Rossi P, Aramini JM, Xiao R, Chen CX, Nwosu C, Owens LA, Maglaqui M, Nair R, Fischer M, Acton TB, Honig B, Rost B, Montelione GT.

Proteins. 2009 Feb 1;74(2):515-9. doi: 10.1002/prot.22267. No abstract available.


Quantum chemical 13C(alpha) chemical shift calculations for protein NMR structure determination, refinement, and validation.

Vila JA, Aramini JM, Rossi P, Kuzin A, Su M, Seetharaman J, Xiao R, Tong L, Montelione GT, Scheraga HA.

Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14389-94. doi: 10.1073/pnas.0807105105. Epub 2008 Sep 11.


Solution NMR structure of the NlpC/P60 domain of lipoprotein Spr from Escherichia coli: structural evidence for a novel cysteine peptidase catalytic triad.

Aramini JM, Rossi P, Huang YJ, Zhao L, Jiang M, Maglaqui M, Xiao R, Locke J, Nair R, Rost B, Acton TB, Inouye M, Montelione GT.

Biochemistry. 2008 Sep 16;47(37):9715-7. doi: 10.1021/bi8010779. Epub 2008 Aug 21.


Solution NMR structure of the SOS response protein YnzC from Bacillus subtilis.

Aramini JM, Sharma S, Huang YJ, Swapna GV, Ho CK, Shetty K, Cunningham K, Ma LC, Zhao L, Owens LA, Jiang M, Xiao R, Liu J, Baran MC, Acton TB, Rost B, Montelione GT.

Proteins. 2008 Jul;72(1):526-30. doi: 10.1002/prot.22064. No abstract available.


Consistent blind protein structure generation from NMR chemical shift data.

Shen Y, Lange O, Delaglio F, Rossi P, Aramini JM, Liu G, Eletsky A, Wu Y, Singarapu KK, Lemak A, Ignatchenko A, Arrowsmith CH, Szyperski T, Montelione GT, Baker D, Bax A.

Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4685-90. doi: 10.1073/pnas.0800256105. Epub 2008 Mar 7.


Solution NMR structure of Escherichia coli ytfP expands the structural coverage of the UPF0131 protein domain family.

Aramini JM, Huang YJ, Swapna GV, Cort JR, Rajan PK, Xiao R, Shastry R, Acton TB, Liu J, Rost B, Kennedy MA, Montelione GT.

Proteins. 2007 Aug 15;68(3):789-95. No abstract available.


Microgram-scale protein structure determination by NMR.

Aramini JM, Rossi P, Anklin C, Xiao R, Montelione GT.

Nat Methods. 2007 Jun;4(6):491-3. Epub 2007 May 13.


SPINS: a laboratory information management system for organizing and archiving intermediate and final results from NMR protein structure determinations.

Baran MC, Moseley HN, Aramini JM, Bayro MJ, Monleon D, Locke JY, Montelione GT.

Proteins. 2006 Mar 1;62(4):843-51.


1H, 13C, and 15N resonance assignments for Escherichia coli ytfP, a member of the broadly conserved UPF0131 protein domain family.

Aramini JM, Swapna GV, Huang YJ, Rajan PK, Xiao R, Shastry R, Acton TB, Cort JR, Kennedy MA, Montelione GT.

J Biomol NMR. 2005 Nov;33(3):197. No abstract available.


Comparisons of NMR spectral quality and success in crystallization demonstrate that NMR and X-ray crystallography are complementary methods for small protein structure determination.

Snyder DA, Chen Y, Denissova NG, Acton T, Aramini JM, Ciano M, Karlin R, Liu J, Manor P, Rajan PA, Rossi P, Swapna GV, Xiao R, Rost B, Hunt J, Montelione GT.

J Am Chem Soc. 2005 Nov 30;127(47):16505-11.


A generalized approach to automated NMR peak list editing: application to reduced dimensionality triple resonance spectra.

Moseley HN, Riaz N, Aramini JM, Szyperski T, Montelione GT.

J Magn Reson. 2004 Oct;170(2):263-77.


Solution structure of a DNA duplex containing an alpha-anomeric adenosine: insights into substrate recognition by endonuclease IV.

Aramini JM, Cleaver SH, Pon RT, Cunningham RP, Germann MW.

J Mol Biol. 2004 Apr 16;338(1):77-91.


Biophysical characterization of the complex between double-stranded RNA and the N-terminal domain of the NS1 protein from influenza A virus: evidence for a novel RNA-binding mode.

Chien CY, Xu Y, Xiao R, Aramini JM, Sahasrabudhe PV, Krug RM, Montelione GT.

Biochemistry. 2004 Feb 24;43(7):1950-62.


Backbone 1H, 15N and 13C assignments for the 21 kDa Caenorhabditis elegans homologue of "brain-specific" protein.

Monleón D, Chiang Y, Aramini JM, Swapna GV, Macapagal D, Gunsalus KC, Kim S, Szyperski T, Montelione GT.

J Biomol NMR. 2004 Jan;28(1):91-2. No abstract available.


Solution NMR structure of the 30S ribosomal protein S28E from Pyrococcus horikoshii.

Aramini JM, Huang YJ, Cort JR, Goldsmith-Fischman S, Xiao R, Shih LY, Ho CK, Liu J, Rost B, Honig B, Kennedy MA, Acton TB, Montelione GT.

Protein Sci. 2003 Dec;12(12):2823-30.


Resonance assignments for the hypothetical protein yggU from Escherichia coli.

Aramini JM, Mills JL, Xiao R, Acton TB, Wu MJ, Szyperski T, Montelione GT.

J Biomol NMR. 2003 Nov;27(3):285-6. No abstract available.


Solution structures of casein peptides: NMR, FTIR, CD, and molecular modeling studies of alphas1-casein, 1-23.

Malin EL, Alaimo MH, Brown EM, Aramini JM, Germann MW, Farrell HM Jr, McSweeney PL, Fox PF.

J Protein Chem. 2001 Jul;20(5):391-404.


Structural, dynamic, and enzymatic properties of mixed alpha/beta-oligonucleotides containing polarity reversals.

Germann MW, Aramini JM, Kalisch BW, van de Sande JH.

Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):493-9. Review.


NMR studies of DNA duplexes containing alpha-anomeric nucleotides and polarity reversals.

Aramini JM, Germann MW.

Biochem Cell Biol. 1998;76(2-3):403-10. Review.


Quadrupolar metal ion NMR studies of metalloproteins.

Aramini JM, Vogel HJ.

Biochem Cell Biol. 1998;76(2-3):210-22. Review.


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