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Items: 25

1.

Long-Term Cardiovascular Risk in Women With Hypertension During Pregnancy.

Honigberg MC, Zekavat SM, Aragam K, Klarin D, Bhatt DL, Scott NS, Peloso GM, Natarajan P.

J Am Coll Cardiol. 2019 Nov 6. pii: S0735-1097(19)37919-7. doi: 10.1016/j.jacc.2019.09.052. [Epub ahead of print]

PMID:
31727424
2.

Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease.

Klarin D, Busenkell E, Judy R, Lynch J, Levin M, Haessler J, Aragam K, Chaffin M, Haas M, Lindström S, Assimes TL, Huang J, Min Lee K, Shao Q, Huffman JE, Kabrhel C, Huang Y, Sun YV, Vujkovic M, Saleheen D, Miller DR, Reaven P, DuVall S, Boden WE, Pyarajan S, Reiner AP, Trégouët DA, Henke P, Kooperberg C, Gaziano JM, Concato J, Rader DJ, Cho K, Chang KM, Wilson PWF, Smith NL, O'Donnell CJ, Tsao PS, Kathiresan S, Obi A, Damrauer SM, Natarajan P; INVENT Consortium; Veterans Affairs’ Million Veteran Program.

Nat Genet. 2019 Nov;51(11):1574-1579. doi: 10.1038/s41588-019-0519-3. Epub 2019 Nov 1.

PMID:
31676865
3.

Response by Aragam et al to Letter Regarding Article, "Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery".

Aragam KG, Chaffin M, Ellinor PT, Kathiresan S, Lubitz SA.

Circulation. 2019 Jul 2;140(1):e7-e8. doi: 10.1161/CIRCULATIONAHA.119.040940. Epub 2019 Jul 1. No abstract available.

PMID:
31549875
4.

Sleep Duration and Myocardial Infarction.

Daghlas I, Dashti HS, Lane J, Aragam KG, Rutter MK, Saxena R, Vetter C.

J Am Coll Cardiol. 2019 Sep 10;74(10):1304-1314. doi: 10.1016/j.jacc.2019.07.022.

PMID:
31488267
5.

Genome-wide association study of peripheral artery disease in the Million Veteran Program.

Klarin D, Lynch J, Aragam K, Chaffin M, Assimes TL, Huang J, Lee KM, Shao Q, Huffman JE, Natarajan P, Arya S, Small A, Sun YV, Vujkovic M, Freiberg MS, Wang L, Chen J, Saleheen D, Lee JS, Miller DR, Reaven P, Alba PR, Patterson OV, DuVall SL, Boden WE, Beckman JA, Gaziano JM, Concato J, Rader DJ, Cho K, Chang KM, Wilson PWF, O'Donnell CJ, Kathiresan S; VA Million Veteran Program, Tsao PS, Damrauer SM.

Nat Med. 2019 Aug;25(8):1274-1279. doi: 10.1038/s41591-019-0492-5. Epub 2019 Jul 8.

PMID:
31285632
6.

Genetic Association of Finger Photoplethysmography-Derived Arterial Stiffness Index With Blood Pressure and Coronary Artery Disease.

Zekavat SM, Aragam K, Emdin C, Khera AV, Klarin D, Zhao H, Natarajan P.

Arterioscler Thromb Vasc Biol. 2019 Jun;39(6):1253-1261. doi: 10.1161/ATVBAHA.119.312626.

PMID:
31070453
7.

Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood.

Khera AV, Chaffin M, Wade KH, Zahid S, Brancale J, Xia R, Distefano M, Senol-Cosar O, Haas ME, Bick A, Aragam KG, Lander ES, Smith GD, Mason-Suares H, Fornage M, Lebo M, Timpson NJ, Kaplan LM, Kathiresan S.

Cell. 2019 Apr 18;177(3):587-596.e9. doi: 10.1016/j.cell.2019.03.028.

PMID:
31002795
8.

Biological and clinical insights from genetics of insomnia symptoms.

Lane JM, Jones SE, Dashti HS, Wood AR, Aragam KG, van Hees VT, Strand LB, Winsvold BS, Wang H, Bowden J, Song Y, Patel K, Anderson SG, Beaumont RN, Bechtold DA, Cade BE, Haas M, Kathiresan S, Little MA, Luik AI, Loudon AS, Purcell S, Richmond RC, Scheer FAJL, Schormair B, Tyrrell J, Winkelman JW, Winkelmann J; HUNT All In Sleep, Hveem K, Zhao C, Nielsen JB, Willer CJ, Redline S, Spiegelhalder K, Kyle SD, Ray DW, Zwart JA, Brumpton B, Frayling TM, Lawlor DA, Rutter MK, Weedon MN, Saxena R.

Nat Genet. 2019 Mar;51(3):387-393. doi: 10.1038/s41588-019-0361-7. Epub 2019 Feb 25.

9.

Cardiometabolic Polygenic Risk Scores and Osteoarthritis Outcomes: A Mendelian Randomization Study Using Data From the Malmö Diet and Cancer Study and the UK Biobank.

Hindy G, Åkesson KE, Melander O, Aragam KG, Haas ME, Nilsson PM, Kadam UT, Orho-Melander M.

Arthritis Rheumatol. 2019 Jun;71(6):925-934. doi: 10.1002/art.40812. Epub 2019 Apr 17.

10.

Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery.

Aragam KG, Chaffin M, Levinson RT, McDermott G, Choi SH, Shoemaker MB, Haas ME, Weng LC, Lindsay ME, Smith JG, Newton-Cheh C, Roden DM, London B, Wells QS, Ellinor PT, Kathiresan S, Lubitz SA; GRADE Investigators.

Circulation. 2018 Nov 11. doi: 10.1161/CIRCULATIONAHA.118.035774. [Epub ahead of print]

PMID:
30586722
11.

DNA Sequence Variation in ACVR1C Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes.

Emdin CA, Khera AV, Aragam K, Haas M, Chaffin M, Klarin D, Natarajan P, Bick A, Zekavat SM, Nomura A, Ardissino D, Wilson JG, Schunkert H, McPherson R, Watkins H, Elosua R, Bown MJ, Samani NJ, Baber U, Erdmann J, Gupta N, Danesh J, Saleheen D, Gabriel S, Kathiresan S.

Diabetes. 2019 Jan;68(1):226-234. doi: 10.2337/db18-0857. Epub 2018 Nov 2.

12.

Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure.

Haas ME, Aragam KG, Emdin CA, Bick AG; International Consortium for Blood Pressure, Hemani G, Davey Smith G, Kathiresan S.

Am J Hum Genet. 2018 Oct 4;103(4):461-473. doi: 10.1016/j.ajhg.2018.08.004. Epub 2018 Sep 13.

13.

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations.

Khera AV, Chaffin M, Aragam KG, Haas ME, Roselli C, Choi SH, Natarajan P, Lander ES, Lubitz SA, Ellinor PT, Kathiresan S.

Nat Genet. 2018 Sep;50(9):1219-1224. doi: 10.1038/s41588-018-0183-z. Epub 2018 Aug 13.

14.

Multi-ethnic genome-wide association study for atrial fibrillation.

Roselli C, Chaffin MD, Weng LC, Aeschbacher S, Ahlberg G, Albert CM, Almgren P, Alonso A, Anderson CD, Aragam KG, Arking DE, Barnard J, Bartz TM, Benjamin EJ, Bihlmeyer NA, Bis JC, Bloom HL, Boerwinkle E, Bottinger EB, Brody JA, Calkins H, Campbell A, Cappola TP, Carlquist J, Chasman DI, Chen LY, Chen YI, Choi EK, Choi SH, Christophersen IE, Chung MK, Cole JW, Conen D, Cook J, Crijns HJ, Cutler MJ, Damrauer SM, Daniels BR, Darbar D, Delgado G, Denny JC, Dichgans M, Dörr M, Dudink EA, Dudley SC, Esa N, Esko T, Eskola M, Fatkin D, Felix SB, Ford I, Franco OH, Geelhoed B, Grewal RP, Gudnason V, Guo X, Gupta N, Gustafsson S, Gutmann R, Hamsten A, Harris TB, Hayward C, Heckbert SR, Hernesniemi J, Hocking LJ, Hofman A, Horimoto ARVR, Huang J, Huang PL, Huffman J, Ingelsson E, Ipek EG, Ito K, Jimenez-Conde J, Johnson R, Jukema JW, Kääb S, Kähönen M, Kamatani Y, Kane JP, Kastrati A, Kathiresan S, Katschnig-Winter P, Kavousi M, Kessler T, Kietselaer BL, Kirchhof P, Kleber ME, Knight S, Krieger JE, Kubo M, Launer LJ, Laurikka J, Lehtimäki T, Leineweber K, Lemaitre RN, Li M, Lim HE, Lin HJ, Lin H, Lind L, Lindgren CM, Lokki ML, London B, Loos RJF, Low SK, Lu Y, Lyytikäinen LP, Macfarlane PW, Magnusson PK, Mahajan A, Malik R, Mansur AJ, Marcus GM, Margolin L, Margulies KB, März W, McManus DD, Melander O, Mohanty S, Montgomery JA, Morley MP, Morris AP, Müller-Nurasyid M, Natale A, Nazarian S, Neumann B, Newton-Cheh C, Niemeijer MN, Nikus K, Nilsson P, Noordam R, Oellers H, Olesen MS, Orho-Melander M, Padmanabhan S, Pak HN, Paré G, Pedersen NL, Pera J, Pereira A, Porteous D, Psaty BM, Pulit SL, Pullinger CR, Rader DJ, Refsgaard L, Ribasés M, Ridker PM, Rienstra M, Risch L, Roden DM, Rosand J, Rosenberg MA, Rost N, Rotter JI, Saba S, Sandhu RK, Schnabel RB, Schramm K, Schunkert H, Schurman C, Scott SA, Seppälä I, Shaffer C, Shah S, Shalaby AA, Shim J, Shoemaker MB, Siland JE, Sinisalo J, Sinner MF, Slowik A, Smith AV, Smith BH, Smith JG, Smith JD, Smith NL, Soliman EZ, Sotoodehnia N, Stricker BH, Sun A, Sun H, Svendsen JH, Tanaka T, Tanriverdi K, Taylor KD, Teder-Laving M, Teumer A, Thériault S, Trompet S, Tucker NR, Tveit A, Uitterlinden AG, Van Der Harst P, Van Gelder IC, Van Wagoner DR, Verweij N, Vlachopoulou E, Völker U, Wang B, Weeke PE, Weijs B, Weiss R, Weiss S, Wells QS, Wiggins KL, Wong JA, Woo D, Worrall BB, Yang PS, Yao J, Yoneda ZT, Zeller T, Zeng L, Lubitz SA, Lunetta KL, Ellinor PT.

Nat Genet. 2018 Jun 11;50(9):1225-1233. doi: 10.1038/s41588-018-0133-9.

15.

Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease.

Emdin CA, Khera AV, Chaffin M, Klarin D, Natarajan P, Aragam K, Haas M, Bick A, Zekavat SM, Nomura A, Ardissino D, Wilson JG, Schunkert H, McPherson R, Watkins H, Elosua R, Bown MJ, Samani NJ, Baber U, Erdmann J, Gupta N, Danesh J, Chasman D, Ridker P, Denny J, Bastarache L, Lichtman JH, D'Onofrio G, Mattera J, Spertus JA, Sheu WH, Taylor KD, Psaty BM, Rich SS, Post W, Rotter JI, Chen YI, Krumholz H, Saleheen D, Gabriel S, Kathiresan S.

Nat Commun. 2018 Apr 24;9(1):1613. doi: 10.1038/s41467-018-03911-8.

16.

Prognosis of patients with secondary mitral regurgitation and reduced ejection fraction.

Mowakeaa S, Dwivedi A, Grossman JR, Parikh G, Curillova Z, Aragam KG, Elmariah S, Kinlay S, Aragam J.

Open Heart. 2018 Jan 9;5(1):e000745. doi: 10.1136/openhrt-2017-000745. eCollection 2018.

17.

"Road Map" to Improving Enrollment in Cardiac Rehabilitation: Identifying Barriers and Evaluating Alternatives.

Pirruccello JP, Traynor K, Aragam KG.

J Am Heart Assoc. 2017 Oct 11;6(10). pii: e007468. doi: 10.1161/JAHA.117.007468. No abstract available.

18.

Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling.

Emdin CA, Khera AV, Klarin D, Natarajan P, Zekavat SM, Nomura A, Haas M, Aragam K, Ardissino D, Wilson JG, Schunkert H, McPherson R, Watkins H, Elosua R, Bown MJ, Samani NJ, Baber U, Erdmann J, Gormley P, Palotie A, Stitziel NO, Gupta N, Danesh J, Saleheen D, Gabriel S, Kathiresan S.

Circulation. 2018 Jan 16;137(3):222-232. doi: 10.1161/CIRCULATIONAHA.117.028021. Epub 2017 Oct 5.

19.

Preparing Fellows for Precision Cardiology: Are We Ready?

Vaduganathan M, Qamar A, Aragam K.

J Am Coll Cardiol. 2017 Sep 26;70(13):1675-1679. doi: 10.1016/j.jacc.2017.08.020. No abstract available.

20.

Reply: The Gaps in Cardiac Rehabilitation Referral: The Elephant in the Room.

Aragam KG, Seth M, Gurm HS.

J Am Coll Cardiol. 2015 Dec 8;66(22):2574-5. doi: 10.1016/j.jacc.2015.09.064. No abstract available.

21.

Gaps in referral to cardiac rehabilitation of patients undergoing percutaneous coronary intervention in the United States.

Aragam KG, Dai D, Neely ML, Bhatt DL, Roe MT, Rumsfeld JS, Gurm HS.

J Am Coll Cardiol. 2015 May 19;65(19):2079-88. doi: 10.1016/j.jacc.2015.02.063.

22.

The ethics of pacemaker reuse: might the best be the enemy of the good?

Aragam KG, Baman TS, Kirkpatrick JN, Goldman EB, Brown AC, Crawford T, Oral H, Eagle KA.

Heart. 2011 Dec;97(24):2005-6. doi: 10.1136/heartjnl-2011-301031. Epub 2011 Oct 13. Review. No abstract available.

PMID:
21997673
23.

Trends and disparities in referral to cardiac rehabilitation after percutaneous coronary intervention.

Aragam KG, Moscucci M, Smith DE, Riba AL, Zainea M, Chambers JL, Share D, Gurm HS.

Am Heart J. 2011 Mar;161(3):544-551.e2. doi: 10.1016/j.ahj.2010.11.016.

PMID:
21392610
24.

Antiplatelet therapy in acute coronary syndromes.

Aragam KG, Bhatt DL.

J Cardiovasc Pharmacol Ther. 2011 Mar;16(1):24-42. doi: 10.1177/1074248410381758. Epub 2010 Oct 5. Review.

PMID:
20924098
25.

Does simplicity compromise accuracy in ACS risk prediction? A retrospective analysis of the TIMI and GRACE risk scores.

Aragam KG, Tamhane UU, Kline-Rogers E, Li J, Fox KA, Goodman SG, Eagle KA, Gurm HS.

PLoS One. 2009 Nov 23;4(11):e7947. doi: 10.1371/journal.pone.0007947.

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