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Items: 9


Integrated analysis of genetic variation and gene expression reveals novel variant for increased warfarin dose requirement in African Americans.

Hernandez W, Gamazon ER, Aquino-Michaels K, Smithberger E, O'Brien TJ, Harralson AF, Tuck M, Barbour A, Cavallari LH, Perera MA.

J Thromb Haemost. 2017 Apr;15(4):735-743. doi: 10.1111/jth.13639. Epub 2017 Mar 25.


Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues.

Wheeler HE, Shah KP, Brenner J, Garcia T, Aquino-Michaels K; GTEx Consortium, Cox NJ, Nicolae DL, Im HK.

PLoS Genet. 2016 Nov 11;12(11):e1006423. doi: 10.1371/journal.pgen.1006423. eCollection 2016 Nov.


The composition of the microbiota modulates allograft rejection.

Lei YM, Chen L, Wang Y, Stefka AT, Molinero LL, Theriault B, Aquino-Michaels K, Sivan AS, Nagler CR, Gajewski TF, Chong AS, Bartman C, Alegre ML.

J Clin Invest. 2016 Jul 1;126(7):2736-44. doi: 10.1172/JCI85295. Epub 2016 Jun 20.


Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy.

Sivan A, Corrales L, Hubert N, Williams JB, Aquino-Michaels K, Earley ZM, Benyamin FW, Lei YM, Jabri B, Alegre ML, Chang EB, Gajewski TF.

Science. 2015 Nov 27;350(6264):1084-9. doi: 10.1126/science.aac4255. Epub 2015 Nov 5.


A gene-based association method for mapping traits using reference transcriptome data.

Gamazon ER, Wheeler HE, Shah KP, Mozaffari SV, Aquino-Michaels K, Carroll RJ, Eyler AE, Denny JC; GTEx Consortium, Nicolae DL, Cox NJ, Im HK.

Nat Genet. 2015 Sep;47(9):1091-8. doi: 10.1038/ng.3367. Epub 2015 Aug 10.


Novel single nucleotide polymorphism in CYP2C9 is associated with changes in warfarin clearance and CYP2C9 expression levels in African Americans.

Hernandez W, Aquino-Michaels K, Drozda K, Patel S, Jeong Y, Takahashi H, Cavallari LH, Perera MA.

Transl Res. 2015 Jun;165(6):651-7. doi: 10.1016/j.trsl.2014.11.006. Epub 2014 Nov 22.


Poly-omic prediction of complex traits: OmicKriging.

Wheeler HE, Aquino-Michaels K, Gamazon ER, Trubetskoy VV, Dolan ME, Huang RS, Cox NJ, Im HK.

Genet Epidemiol. 2014 Jul;38(5):402-15. doi: 10.1002/gepi.21808. Epub 2014 May 2.


Ethnicity-specific pharmacogenetics: the case of warfarin in African Americans.

Hernandez W, Gamazon ER, Aquino-Michaels K, Patel S, O'Brien TJ, Harralson AF, Kittles RA, Barbour A, Tuck M, McIntosh SD, Douglas JN, Nicolae D, Cavallari LH, Perera MA.

Pharmacogenomics J. 2014 Jun;14(3):223-8. doi: 10.1038/tpj.2013.34. Epub 2013 Sep 10.


Association of the GGCX (CAA)16/17 repeat polymorphism with higher warfarin dose requirements in African Americans.

Cavallari LH, Perera M, Wadelius M, Deloukas P, Taube G, Patel SR, Aquino-Michaels K, Viana MA, Shapiro NL, Nutescu EA.

Pharmacogenet Genomics. 2012 Feb;22(2):152-8. doi: 10.1097/FPC.0b013e32834f288f.

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