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Non-genotoxic MDM2 inhibition selectively induces a pro-apoptotic p53 gene signature in chronic lymphocytic leukemia cells.

Ciardullo C, Aptullahoglu E, Woodhouse L, Lin WY, Wallis JP, Marr H, Marshall S, Bown N, Willmore E, Lunec J.

Haematologica. 2019 Dec;104(12):2429-2442. doi: 10.3324/haematol.2018.206631. Epub 2019 Apr 19.


In situ detection of JAK2V617F within viable hematopoietic cells using gold nanoparticle technology.

Sozer S, Aptullahoglu E, Shivarov V, Yavuz AS.

Int J Lab Hematol. 2019 Aug;41(4):e95-e98. doi: 10.1111/ijlh.12991. Epub 2019 Mar 1. No abstract available.


Targeting negative regulation of p53 by MDM2 and WIP1 as a therapeutic strategy in cutaneous melanoma.

Wu CE, Esfandiari A, Ho YH, Wang N, Mahdi AK, Aptullahoglu E, Lovat P, Lunec J.

Br J Cancer. 2018 Feb 20;118(4):495-508. doi: 10.1038/bjc.2017.433. Epub 2017 Dec 12.

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