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An Interactive Mobile Phone App (SMART 5-A-DAY) for Increasing Knowledge of and Adherence to Fruit and Vegetable Recommendations: Development and Pilot Randomized Controlled Trial.

Appleton KM, Passmore D, Burn I, Pidgeon H, Nation P, Boobyer C, Jiang N.

JMIR Mhealth Uhealth. 2019 Nov 20;7(11):e14380. doi: 10.2196/14380.


A Mobile Phone App for the Provision of Personalized Food-Based Information in an Eating-Out Situation: Development and Initial Evaluation.

Appleton KM, Bray J, Price S, Liebchen G, Jiang N, Mavridis I, Saulais L, Giboreau A, Perez-Cueto FJA, Coolen R, Ronge M, Hartwell H.

JMIR Form Res. 2019 Nov 4;3(4):e12966. doi: 10.2196/12966.


Rho-mediated signaling promotes BRAF inhibitor resistance in de-differentiated melanoma cells.

Misek SA, Appleton KM, Dexheimer TS, Lisabeth EM, Lo RS, Larsen SD, Gallo KA, Neubig RR.

Oncogene. 2019 Oct 28. doi: 10.1038/s41388-019-1074-1. [Epub ahead of print]


Treatments for depression: Side-effects, adverse events and health risks.

Kirsch I, Ness AR, Appleton KM.

J Affect Disord. 2019 Dec 1;259:38-39. doi: 10.1016/j.jad.2019.08.018. Epub 2019 Aug 13. No abstract available.


Modelling positive consequences: Increased vegetable intakes following modelled enjoyment versus modelled intake.

Appleton KM, Barrie E, Samuel TJ.

Appetite. 2019 Sep 1;140:76-81. doi: 10.1016/j.appet.2019.05.003. Epub 2019 May 3.


A Web-Based Intervention (MotivATE) to Increase Attendance at an Eating Disorder Service Assessment Appointment: Zelen Randomized Controlled Trial.

Denison-Day J, Muir S, Newell C, Appleton KM.

J Med Internet Res. 2019 Feb 27;21(2):e11874. doi: 10.2196/11874.


Trial to Encourage Adoption and Maintenance of a Mediterranean Diet (TEAM-MED): Protocol for a Randomised Feasibility Trial of a Peer Support Intervention for Dietary Behaviour Change in Adults at High Cardiovascular Disease Risk.

McEvoy CT, Moore SE, Appleton KM, Cupples ME, Erwin CM, Hunter SJ, Kee F, McCance D, Patterson CC, Young IS, McKinley MC, Woodside JV.

Int J Environ Res Public Health. 2018 May 31;15(6). pii: E1130. doi: 10.3390/ijerph15061130.


The Psychology of Nutrition with Advancing Age: Focus on Food Neophobia.

van den Heuvel E, Newbury A, Appleton KM.

Nutrients. 2019 Jan 12;11(1). pii: E151. doi: 10.3390/nu11010151.


Development of a peer support intervention to encourage dietary behaviour change towards a Mediterranean diet in adults at high cardiovascular risk.

McEvoy CT, Moore SE, Appleton KM, Cupples ME, Erwin C, Kee F, Prior L, Young IS, McKinley MC, Woodside JV.

BMC Public Health. 2018 Oct 22;18(1):1194. doi: 10.1186/s12889-018-6108-z.


Towards a Food-Based Intervention to Increase Protein Intakes in Older Adults: Challenges to and Facilitators of Egg Consumption.

van den Heuvel E, Murphy JL, Appleton KM.

Nutrients. 2018 Oct 2;10(10). pii: E1409. doi: 10.3390/nu10101409.


Could Eggs Help Increase Dietary Protein Intake in Older Adults? - Exploring Reasons for the Consumption and Non-Consumption of Eggs in People over 55 years old.

van den Heuvel E, Murphy JL, Appleton KM.

J Nutr Gerontol Geriatr. 2018 Jul-Dec;37(3-4):292-309. doi: 10.1080/21551197.2018.1505577. Epub 2018 Sep 14.


Improving motivation to change amongst individuals with eating disorders: A systematic review.

Denison-Day J, Appleton KM, Newell C, Muir S.

Int J Eat Disord. 2018 Sep;51(9):1033-1050. doi: 10.1002/eat.22945. Epub 2018 Sep 6.


Sweet taste exposure and the subsequent acceptance and preference for sweet taste in the diet: systematic review of the published literature.

Appleton KM, Tuorila H, Bertenshaw EJ, de Graaf C, Mela DJ.

Am J Clin Nutr. 2018 Mar 1;107(3):405-419. doi: 10.1093/ajcn/nqx031.


The value of facial attractiveness for encouraging fruit and vegetable consumption: analyses from a randomized controlled trial.

Appleton KM, McGrath AJ, McKinley MC, Draffin CR, Hamill LL, Young IS, Woodside JV.

BMC Public Health. 2018 Mar 1;18(1):298. doi: 10.1186/s12889-018-5202-6.


A Systematic Review of Behavioural Interventions Promoting Healthy Eating among Older People.

Zhou X, Perez-Cueto FJA, Santos QD, Monteleone E, Giboreau A, Appleton KM, Bjørner T, Bredie WLP, Hartwell H.

Nutrients. 2018 Jan 26;10(2). pii: E128. doi: 10.3390/nu10020128. Review.


Consumption of a High Quantity and a Wide Variety of Vegetables Are Predicted by Different Food Choice Motives in Older Adults from France, Italy and the UK.

Appleton KM, Dinnella C, Spinelli S, Morizet D, Saulais L, Hemingway A, Monteleone E, Depezay L, Perez-Cueto FJA, Hartwell H.

Nutrients. 2017 Aug 23;9(9). pii: E923. doi: 10.3390/nu9090923.


MotivATE: A Pretreatment Web-Based Program to Improve Attendance at UK Outpatient Services Among Adults With Eating Disorders.

Muir S, Newell C, Griffiths J, Walker K, Hooper H, Thomas S, Thomas PW, Arcelus J, Day J, Appleton KM.

JMIR Res Protoc. 2017 Jul 26;6(7):e146. doi: 10.2196/resprot.7440.


Low fruit and vegetable consumption is associated with low knowledge of the details of the 5-a-day fruit and vegetable message in the UK: findings from two cross-sectional questionnaire studies.

Appleton KM, Krumplevska K, Smith E, Rooney C, McKinley MC, Woodside JV.

J Hum Nutr Diet. 2018 Feb;31(1):121-130. doi: 10.1111/jhn.12487. Epub 2017 Jun 2.


Comparison of three nudge interventions (priming, default option, and perceived variety) to promote vegetable consumption in a self-service buffet setting.

Friis R, Skov LR, Olsen A, Appleton KM, Saulais L, Dinnella C, Hartwell H, Depezay L, Monteleone E, Giboreau A, Perez-Cueto FJA.

PLoS One. 2017 May 31;12(5):e0176028. doi: 10.1371/journal.pone.0176028. eCollection 2017.


Limited compensation at the following meal for protein and energy intake at a lunch meal in healthy free-living older adults.

Appleton KM.

Clin Nutr. 2018 Jun;37(3):970-977. doi: 10.1016/j.clnu.2017.03.032. Epub 2017 Apr 7.


The protective effects of social bonding on behavioral and pituitary-adrenal axis reactivity to chronic mild stress in prairie voles.

McNeal N, Appleton KM, Johnson AK, Scotti ML, Wardwell J, Murphy R, Bishop C, Knecht A, Grippo AJ.

Stress. 2017 Mar;20(2):175-182. doi: 10.1080/10253890.2017.1295444. Epub 2017 Mar 5.


Greater fruit selection following an appearance-based compared with a health-based health promotion poster.

Appleton KM.

J Public Health (Oxf). 2016 Dec 2;38(4):731-738. doi: 10.1093/pubmed/fdv147. No abstract available.


The efficacy of fish oil supplements in the treatment of depression: food for thought.

Bastiaansen JA, Munafò MR, Appleton KM, Oldehinkel AJ.

Transl Psychiatry. 2016 Dec 6;6(12):e975. doi: 10.1038/tp.2016.243. No abstract available.


S1P in HDL promotes interaction between SR-BI and S1PR1 and activates S1PR1-mediated biological functions: calcium flux and S1PR1 internalization.

Lee MH, Appleton KM, El-Shewy HM, Sorci-Thomas MG, Thomas MJ, Lopes-Virella MF, Luttrell LM, Hammad SM, Klein RL.

J Lipid Res. 2017 Feb;58(2):325-338. doi: 10.1194/jlr.M070706. Epub 2016 Nov 23.


Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC-Overexpressing Melanoma.

Haak AJ, Appleton KM, Lisabeth EM, Misek SA, Ji Y, Wade SM, Bell JL, Rockwell CE, Airik M, Krook MA, Larsen SD, Verhaegen M, Lawlor ER, Neubig RR.

Mol Cancer Ther. 2017 Jan;16(1):193-204. doi: 10.1158/1535-7163.MCT-16-0482. Epub 2016 Nov 11.


Sensory determinants of stated liking for vegetable names and actual liking for canned vegetables: A cross-country study among European adolescents.

Dinnella C, Morizet D, Masi C, Cliceri D, Depezay L, Appleton KM, Giboreau A, Perez-Cueto FJA, Hartwell H, Monteleone E.

Appetite. 2016 Dec 1;107:339-347. doi: 10.1016/j.appet.2016.08.110. Epub 2016 Aug 22.


How much is '5-a-day'? A qualitative investigation into consumer understanding of fruit and vegetable intake guidelines.

Rooney C, McKinley MC, Appleton KM, Young IS, McGrath AJ, Draffin CR, Hamill LL, Woodside JV.

J Hum Nutr Diet. 2017 Feb;30(1):105-113. doi: 10.1111/jhn.12393. Epub 2016 Jun 22.


The conformational signature of β-arrestin2 predicts its trafficking and signalling functions.

Lee MH, Appleton KM, Strungs EG, Kwon JY, Morinelli TA, Peterson YK, Laporte SA, Luttrell LM.

Nature. 2016 Mar 31;531(7596):665-8. doi: 10.1038/nature17154. Epub 2016 Mar 23.


A Role for Behavior in the Relationships Between Depression and Hostility and Cardiovascular Disease Incidence, Mortality, and All-Cause Mortality: the Prime Study.

Appleton KM, Woodside JV, Arveiler D, Haas B, Amouyel P, Montaye M, Ferrieres J, Ruidavets JB, Yarnell JW, Kee F, Evans A, Bingham A, Ducimetiere P, Patterson CC; PRIME study group.

Ann Behav Med. 2016 Aug;50(4):582-91. doi: 10.1007/s12160-016-9784-x.


ω-3 Fatty acids for major depressive disorder in adults: an abridged Cochrane review.

Appleton KM, Sallis HM, Perry R, Ness AR, Churchill R.

BMJ Open. 2016 Mar 2;6(3):e010172. doi: 10.1136/bmjopen-2015-010172. Review. Erratum in: BMJ Open. 2017 Jan 16;7(1):e010172corr1.


The Predictive Value of Depressive Symptoms for All-Cause Mortality: Findings From the PRIME Belfast Study Examining the Role of Inflammation and Cardiovascular Risk Markers.

Hughes MF, Patterson CC, Appleton KM, Blankenberg S, Woodside JV, Donnelly M, Linden G, Zeller T, Esquirol Y, Kee F.

Psychosom Med. 2016 May;78(4):401-11. doi: 10.1097/PSY.0000000000000289.


Increasing vegetable intakes: rationale and systematic review of published interventions.

Appleton KM, Hemingway A, Saulais L, Dinnella C, Monteleone E, Depezay L, Morizet D, Armando Perez-Cueto FJ, Bevan A, Hartwell H.

Eur J Nutr. 2016 Apr;55(3):869-96. doi: 10.1007/s00394-015-1130-8. Epub 2016 Jan 11. Review.


Participating in a fruit and vegetable intervention trial improves longer term fruit and vegetable consumption and barriers to fruit and vegetable consumption: a follow-up of the ADIT study.

Neville CE, McKinley MC, Draffin CR, Gallagher NE, Appleton KM, Young IS, Edgar JD, Woodside JV.

Int J Behav Nutr Phys Act. 2015 Dec 18;12:158. doi: 10.1186/s12966-015-0311-4.


Omega-3 fatty acids for depression in adults.

Appleton KM, Sallis HM, Perry R, Ness AR, Churchill R.

Cochrane Database Syst Rev. 2015 Nov 5;(11):CD004692. doi: 10.1002/14651858.CD004692.pub4. Review.


Effect of a Web-Based Behavior Change Program on Weight Loss and Cardiovascular Risk Factors in Overweight and Obese Adults at High Risk of Developing Cardiovascular Disease: Randomized Controlled Trial.

Watson S, Woodside JV, Ware LJ, Hunter SJ, McGrath A, Cardwell CR, Appleton KM, Young IS, McKinley MC.

J Med Internet Res. 2015 Jul 16;17(7):e177. doi: 10.2196/jmir.3828.


Combining vitamin C and carotenoid biomarkers better predicts fruit and vegetable intake than individual biomarkers in dietary intervention studies.

McGrath AJ, Hamill LL, Cardwell CR, Draffin CR, Neville CE, Appleton KM, McEneny J, McKinley MC, Young IS, Woodside JV.

Eur J Nutr. 2016 Jun;55(4):1377-88. doi: 10.1007/s00394-015-0953-7. Epub 2015 Jun 17.


A Role for Identification in the Gradual Decline in the Pleasantness of Flavors With Age.

Appleton KM, Smith E.

J Gerontol B Psychol Sci Soc Sci. 2016 Nov;71(6):987-994. Epub 2015 May 14.


Consumption of a high n-3 polyunsaturated fatty acid diet during gradual mild physiological stress in rats.

Appleton KM, Grippo AJ, Beltz TG, Johnson AK.

Prostaglandins Leukot Essent Fatty Acids. 2015 Apr;95:11-8. doi: 10.1016/j.plefa.2014.11.010. Epub 2014 Dec 4.


Energy compensation in the real world: good compensation for small portions of chocolate and biscuits over short time periods in complicit consumers using commercially available foods.

Appleton KM, McKeown PP, Woodside JV.

Appetite. 2015 Feb;85:104-10. doi: 10.1016/j.appet.2014.11.016. Epub 2014 Nov 18.


Development of inhibitors of heterotrimeric Gαi subunits.

Appleton KM, Bigham KJ, Lindsey CC, Hazard S, Lirjoni J, Parnham S, Hennig M, Peterson YK.

Bioorg Med Chem. 2014 Jul 1;22(13):3423-34. doi: 10.1016/j.bmc.2014.04.035. Epub 2014 Apr 26.


Suppression of GNAI2 message in ovarian cancer.

Raymond JR Jr, Appleton KM, Pierce JY, Peterson YK.

J Ovarian Res. 2014 Jan 14;7:6. doi: 10.1186/1757-2215-7-6.


Visualising future behaviour: Effects for snacking on biscuit bars, but no effects for snacking on fruit.

Adams C, Rennie L, Uskul AK, Appleton KM.

J Health Psychol. 2015 Aug;20(8):1037-48. doi: 10.1177/1359105313506760. Epub 2013 Nov 11.


Depression and mortality: artifact of measurement and analysis?

Appleton KM, Woodside JV, Arveiler D, Haas B, Amouyel P, Montaye M, Ferrieres J, Ruidavets JB, Yarnell JW, Kee F, Evans A, Bingham A, Ducimetiere P, Patterson CC; PRIME study group.

J Affect Disord. 2013 Nov;151(2):632-8. doi: 10.1016/j.jad.2013.07.010. Epub 2013 Jul 29.


The consumption of protein-rich foods in older adults: an exploratory focus group study.

Best RL, Appleton KM.

J Nutr Educ Behav. 2013 Nov-Dec;45(6):751-5. doi: 10.1016/j.jneb.2013.03.008. Epub 2013 Jul 2.


The arrestin-selective angiotensin AT1 receptor agonist [Sar1,Ile4,Ile8]-AngII negatively regulates bradykinin B2 receptor signaling via AT1-B2 receptor heterodimers.

Wilson PC, Lee MH, Appleton KM, El-Shewy HM, Morinelli TA, Peterson YK, Luttrell LM, Jaffa AA.

J Biol Chem. 2013 Jun 28;288(26):18872-84. doi: 10.1074/jbc.M113.472381. Epub 2013 May 9.


Emergent biological properties of arrestin pathway-selective biased agonism.

Appleton KM, Luttrell LM.

J Recept Signal Transduct Res. 2013 Jun;33(3):153-61. doi: 10.3109/10799893.2013.769004. Epub 2013 Feb 28.


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