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Items: 1 to 50 of 69

1.

T-Bet independent development of IFNγ secreting natural T helper 1 cell population in the absence of Itk.

Kannan AK, Mohinta S, Huang W, Huang L, Koylass N, Appleton JA, August A.

Sci Rep. 2017 Apr 13;7:45935. doi: 10.1038/srep45935.

2.

Eosinophils in Helminth Infection: Defenders and Dupes.

Huang L, Appleton JA.

Trends Parasitol. 2016 Oct;32(10):798-807. doi: 10.1016/j.pt.2016.05.004. Epub 2016 Jun 1. Review.

3.

Eosinophils and IL-4 Support Nematode Growth Coincident with an Innate Response to Tissue Injury.

Huang L, Beiting DP, Gebreselassie NG, Gagliardo LF, Ruyechan MC, Lee NA, Lee JJ, Appleton JA.

PLoS Pathog. 2015 Dec 31;11(12):e1005347. doi: 10.1371/journal.ppat.1005347. eCollection 2015 Dec.

4.

Eosinophils mediate protective immunity against secondary nematode infection.

Huang L, Gebreselassie NG, Gagliardo LF, Ruyechan MC, Luber KL, Lee NA, Lee JJ, Appleton JA.

J Immunol. 2015 Jan 1;194(1):283-90. doi: 10.4049/jimmunol.1402219. Epub 2014 Nov 26.

5.

Eosinophil-derived IL-10 supports chronic nematode infection.

Huang L, Gebreselassie NG, Gagliardo LF, Ruyechan MC, Lee NA, Lee JJ, Appleton JA.

J Immunol. 2014 Oct 15;193(8):4178-87. doi: 10.4049/jimmunol.1400852. Epub 2014 Sep 10.

6.

Intestinal infection with Trichinella spiralis induces distinct, regional immune responses.

Blum LK, Mohanan S, Fabre MV, Yafawi RE, Appleton JA.

Vet Parasitol. 2013 May 20;194(2-4):101-5. doi: 10.1016/j.vetpar.2013.01.030. Epub 2013 Feb 5.

7.

Participation of MyD88 and interleukin-33 as innate drivers of Th2 immunity to Trichinella spiralis.

Scalfone LK, Nel HJ, Gagliardo LF, Cameron JL, Al-Shokri S, Leifer CA, Fallon PG, Appleton JA.

Infect Immun. 2013 Apr;81(4):1354-63. doi: 10.1128/IAI.01307-12. Epub 2013 Feb 12.

8.

Comparison of three immunoglobulin G assays for the diagnosis of failure of passive transfer of immunity in neonatal alpacas.

Pinn TL, Gagliardo LF, Purdy SR, Appleton JA, Stokol T.

J Vet Diagn Invest. 2013 Jan;25(1):91-8. doi: 10.1177/1040638712472182.

PMID:
23345272
9.

In vitro modelling of rat mucosal mast cell function in Trichinella spiralis infection.

Thrasher SM, Scalfone LK, Holowka D, Appleton JA.

Parasite Immunol. 2013 Jan;35(1):21-31. doi: 10.1111/pim.12014.

10.

Costs and benefits of immunity to worm infection.

Appleton JA.

J Immunol. 2012 Aug 1;189(3):1101-3. doi: 10.4049/jimmunol.1201596. No abstract available.

11.

Analysis of heavy-chain antibody responses and resistance to Parelaphostrongylus tenuis in experimentally infected alpacas.

Purdy SR, Gagliardo LF, Lefman S, Hamel PJ, Ku S, Mainini T, Hoyt G, Justus K, Daley-Bauer LP, Duffy MS, Appleton JA.

Clin Vaccine Immunol. 2012 Jul;19(7):1019-26. doi: 10.1128/CVI.00178-12. Epub 2012 May 16.

12.

Eosinophils preserve parasitic nematode larvae by regulating local immunity.

Gebreselassie NG, Moorhead AR, Fabre V, Gagliardo LF, Lee NA, Lee JJ, Appleton JA.

J Immunol. 2012 Jan 1;188(1):417-25. doi: 10.4049/jimmunol.1101980. Epub 2011 Nov 30.

13.

Contributions of conventional and heavy-chain IgG to immunity in fetal, neonatal, and adult alpacas.

Daley-Bauer LP, Purdy SR, Smith MC, Gagliardo LF, Davis WC, Appleton JA.

Clin Vaccine Immunol. 2010 Dec;17(12):2007-15. doi: 10.1128/CVI.00287-10. Epub 2010 Oct 6.

14.

Vaccine delivery by polymeric vehicles in the mouse reproductive tract induces sustained local and systemic immunity.

Kuo-Haller P, Cu Y, Blum J, Appleton JA, Saltzman WM.

Mol Pharm. 2010 Oct 4;7(5):1585-95. doi: 10.1021/mp100009e. Epub 2010 Aug 26.

15.

Combinatorial effects of interleukin 10 and interleukin 4 determine the progression of hepatic inflammation following murine enteric parasitic infection.

Douglas DB, Beiting DP, Loftus JP, Appleton JA, Bliss SK.

Hepatology. 2010 Jun;51(6):2162-71. doi: 10.1002/hep.23576.

16.

Effector functions of camelid heavy-chain antibodies in immunity to West Nile virus.

Daley LP, Kutzler MA, Bennett BW, Smith MC, Glaser AL, Appleton JA.

Clin Vaccine Immunol. 2010 Feb;17(2):239-46. doi: 10.1128/CVI.00421-09. Epub 2009 Dec 2.

17.

Expulsion of secondary Trichinella spiralis infection in rats occurs independently of mucosal mast cell release of mast cell protease II.

Blum LK, Thrasher SM, Gagliardo LF, Fabre V, Appleton JA.

J Immunol. 2009 Nov 1;183(9):5816-22. doi: 10.4049/jimmunol.0900944. Epub 2009 Oct 7.

18.

Eosinophil deficiency compromises parasite survival in chronic nematode infection.

Fabre V, Beiting DP, Bliss SK, Gebreselassie NG, Gagliardo LF, Lee NA, Lee JJ, Appleton JA.

J Immunol. 2009 Feb 1;182(3):1577-83.

19.

Immunity to Trichinella spiralis muscle infection.

Fabre MV, Beiting DP, Bliss SK, Appleton JA.

Vet Parasitol. 2009 Feb 23;159(3-4):245-8. doi: 10.1016/j.vetpar.2008.10.051. Epub 2008 Oct 22. Review.

20.

Cloning and analysis of a Trichinella pseudospiralis muscle larva secreted serine protease gene.

Cwiklinski K, Meskill D, Robinson MW, Pozio E, Appleton JA, Connolly B.

Vet Parasitol. 2009 Feb 23;159(3-4):268-71. doi: 10.1016/j.vetpar.2008.10.036. Epub 2008 Oct 22.

21.

Divergent metabolic adaptations to intestinal parasitic nematode infection in mice susceptible or resistant to obesity.

Wong T, Hildebrandt MA, Thrasher SM, Appleton JA, Ahima RS, Wu GD.

Gastroenterology. 2007 Dec;133(6):1979-88. Epub 2007 Sep 14.

22.

IL-10 regulates movement of intestinally derived CD4+ T cells to the liver.

Bliss SK, Bliss SP, Beiting DP, Alcaraz A, Appleton JA.

J Immunol. 2007 Jun 15;178(12):7974-83.

23.

Coordinated control of immunity to muscle stage Trichinella spiralis by IL-10, regulatory T cells, and TGF-beta.

Beiting DP, Gagliardo LF, Hesse M, Bliss SK, Meskill D, Appleton JA.

J Immunol. 2007 Jan 15;178(2):1039-47.

24.

Protein glycosylation in Parelaphostrongylus tenuis--first description of the Galalpha1-3Gal sequence in a nematode.

Duffy MS, Morris HR, Dell A, Appleton JA, Haslam SM.

Glycobiology. 2006 Sep;16(9):854-62. Epub 2006 May 15.

PMID:
16704967
26.

Cathepsin B homologue at the interface between a parasitic nematode and its intermediate host.

Duffy MS, Cevasco DK, Zarlenga DS, Sukhumavasi W, Appleton JA.

Infect Immun. 2006 Feb;74(2):1297-304.

28.

Application of monoclonal antibodies in functional and comparative investigations of heavy-chain immunoglobulins in new world camelids.

Daley LP, Gagliardo LF, Duffy MS, Smith MC, Appleton JA.

Clin Diagn Lab Immunol. 2005 Mar;12(3):380-6.

29.

Interleukin-10 limits local and body cavity inflammation during infection with muscle-stage Trichinella spiralis.

Beiting DP, Bliss SK, Schlafer DH, Roberts VL, Appleton JA.

Infect Immun. 2004 Jun;72(6):3129-37.

30.

IL-10 prevents liver necrosis during murine infection with Trichinella spiralis.

Bliss SK, Alcaraz A, Appleton JA.

J Immunol. 2003 Sep 15;171(6):3142-7.

31.

The effect of strenuous exercise on mRNA concentrations of interleukin-12, interferon-gamma and interleukin-4 in equine pulmonary and peripheral blood mononuclear cells.

Ainsworth DM, Appleton JA, Eicker SW, Luce R, Julia Flaminio M, Antczak DF.

Vet Immunol Immunopathol. 2003 Jan 10;91(1):61-71.

PMID:
12507851
32.

A putative serine protease among the excretory-secretory glycoproteins of L1 Trichinella spiralis.

Romaris F, North SJ, Gagliardo LF, Butcher BA, Ghosh K, Beiting DP, Panico M, Arasu P, Dell A, Morris HR, Appleton JA.

Mol Biochem Parasitol. 2002 Jul;122(2):149-60.

PMID:
12106869
33.

An aspartyl protease inhibitor orthologue expressed by Parelaphostrongylus tenuis is immunogenic in an atypical host.

Duffy MS, MacAfee N, Burt MD, Appleton JA.

Clin Diagn Lab Immunol. 2002 Jul;9(4):763-70.

34.
35.

IgG antibody responses to an inhaled antigen in horses with "heaves" (recurrent airway obstruction).

Ainsworth DM, Appleton JA, Antczak DF, Santiago MA, Aviza G.

Vet Immunol Immunopathol. 2002 Jan 15;84(3-4):169-80.

PMID:
11777532
36.

A pivotal role for glycans at the interface between Trichinella spiralis and its host.

Appleton JA, Romaris F.

Vet Parasitol. 2001 Nov 22;101(3-4):249-60. Review.

PMID:
11707300
37.

Invasion of epithelial cells by Trichinella spiralis: in vitro observations.

Romarís F, Appleton JA.

Parasite. 2001 Jun;8(2 Suppl):S48-50. Review.

38.

Phosphorylcholine-containing N-glycans of Trichinella spiralis: identification of multiantennary lacdiNAc structures.

Morelle W, Haslam SM, Olivier V, Appleton JA, Morris HR, Dell A.

Glycobiology. 2000 Sep;10(9):941-50.

PMID:
10988255
39.

Larvae-induced plasma membrane wounds and glycoprotein deposition are insufficient for Trichinella spiralis invasion of epithelial cells.

Butcher BA, Gagliardo LF, ManWarren T, Appleton JA.

Mol Biochem Parasitol. 2000 Apr 15;107(2):207-18.

PMID:
10779597
40.

Dominance of immunoglobulin G2c in the antiphosphorylcholine response of rats infected with Trichinella spiralis.

Peters PJ, Gagliardo LF, Sabin EA, Betchen AB, Ghosh K, Oblak JB, Appleton JA.

Infect Immun. 1999 Sep;67(9):4661-7.

41.

Terminal beta-linked tyvelose creates unique epitopes in Trichinella spiralis glycan antigens.

Ellis LA, McVay CS, Probert MA, Zhang J, Bundle DR, Appleton JA.

Glycobiology. 1997 Apr;7(3):383-90.

PMID:
9147047
42.

Workshop on a detailed characterization of Trichinella spiralis antigens: a platform for future studies on antigens and antibodies to this parasite.

Ortega-Pierres MG, Yepez-Mulia L, Homan W, Gamble HR, Lim PL, Takahashi Y, Wassom DI, Appleton JA.

Parasite Immunol. 1996 Jun;18(6):273-84. Review.

PMID:
9229380
43.

Molecular analysis of antigens targeted by protective antibodies in rapid expulsion of Trichinella spiralis [Mol. Biochem. Parasitol. 65 (1994) 201].

Arasu P, Ellis LA, Iglesias R, Ubeira FM, Appleton JA.

Mol Biochem Parasitol. 1995 Jul;73(1-2):295. No abstract available.

PMID:
8577344
44.
45.

Novel tyvelose-containing tri- and tetra-antennary N-glycans in the immunodominant antigens of the intracellular parasite Trichinella spiralis.

Reason AJ, Ellis LA, Appleton JA, Wisnewski N, Grieve RB, McNeil M, Wassom DL, Morris HR, Dell A.

Glycobiology. 1994 Oct;4(5):593-603.

PMID:
7881173
46.

Glycans as targets for monoclonal antibodies that protect rats against Trichinella spiralis.

Ellis LA, Reason AJ, Morris HR, Dell A, Iglesias R, Ubeira FM, Appleton JA.

Glycobiology. 1994 Oct;4(5):585-92.

PMID:
7881172
47.

Molecular analysis of antigens targeted by protective antibodies in rapid expulsion of Trichinella spiralis.

Arasu P, Ellis LA, Iglesias R, Ubeira FM, Appleton JA.

Mol Biochem Parasitol. 1994 Jun;65(2):201-11. Erratum in: Mol Biochem Parasitol. 1995 Jul;73(1-2):295.

PMID:
7526209
48.

Trichinella spiralis: the effect of specific antibody on muscle larvae in the small intestines of weaned rats.

Otubu OE, Carlisle-Nowak MS, McGregor DD, Jacobson RH, Appleton JA.

Exp Parasitol. 1993 Jun;76(4):394-400.

PMID:
8513877
49.

Identification of potential antigenic targets for rapid expulsion of Trichinella spiralis.

Appleton JA, Usack L.

Mol Biochem Parasitol. 1993 Mar;58(1):53-62.

PMID:
7681546
50.

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