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Items: 32


Comparative effectiveness of common therapies for Wilson disease: A systematic review and meta-analysis of controlled studies.

Appenzeller-Herzog C, Mathes T, Heeres MLS, Weiss KH, Houwen RHJ, Ewald H.

Liver Int. 2019 Jun 17. doi: 10.1111/liv.14179. [Epub ahead of print]


Human ER Oxidoreductin-1α (Ero1α) Undergoes Dual Regulation through Complementary Redox Interactions with Protein-Disulfide Isomerase.

Kanemura S, Okumura M, Yutani K, Ramming T, Hikima T, Appenzeller-Herzog C, Akiyama S, Inaba K.

J Biol Chem. 2016 Nov 11;291(46):23952-23964. Epub 2016 Oct 4.


ER-luminal thiol/selenol-mediated regulation of Ca2+ signalling.

Appenzeller-Herzog C, Simmen T.

Biochem Soc Trans. 2016 Apr 15;44(2):452-9. doi: 10.1042/BST20150233. Review.


Transit of H2O2 across the endoplasmic reticulum membrane is not sluggish.

Appenzeller-Herzog C, Bánhegyi G, Bogeski I, Davies KJ, Delaunay-Moisan A, Forman HJ, Görlach A, Kietzmann T, Laurindo F, Margittai E, Meyer AJ, Riemer J, Rützler M, Simmen T, Sitia R, Toledano MB, Touw IP.

Free Radic Biol Med. 2016 May;94:157-60. doi: 10.1016/j.freeradbiomed.2016.02.030. Epub 2016 Feb 27.


Cysteines 208 and 241 in Ero1α are required for maximal catalytic turnover.

Ramming T, Kanemura S, Okumura M, Inaba K, Appenzeller-Herzog C.

Redox Biol. 2016 Apr;7:14-20. doi: 10.1016/j.redox.2015.11.004. Epub 2015 Nov 14.


The antioxidant machinery of the endoplasmic reticulum: Protection and signaling.

Delaunay-Moisan A, Appenzeller-Herzog C.

Free Radic Biol Med. 2015 Jun;83:341-51. doi: 10.1016/j.freeradbiomed.2015.02.019. Epub 2015 Mar 2. Review.


A PDI-catalyzed thiol-disulfide switch regulates the production of hydrogen peroxide by human Ero1.

Ramming T, Okumura M, Kanemura S, Baday S, Birk J, Moes S, Spiess M, Jenö P, Bernèche S, Inaba K, Appenzeller-Herzog C.

Free Radic Biol Med. 2015 Jun;83:361-72. doi: 10.1016/j.freeradbiomed.2015.02.011. Epub 2015 Feb 17.


Redox controls UPR to control redox.

Eletto D, Chevet E, Argon Y, Appenzeller-Herzog C.

J Cell Sci. 2014 Sep 1;127(Pt 17):3649-58. doi: 10.1242/jcs.153643. Epub 2014 Aug 8. Review.


Biochemical evidence that regulation of Ero1β activity in human cells does not involve the isoform-specific cysteine 262.

Hansen HG, Søltoft CL, Schmidt JD, Birk J, Appenzeller-Herzog C, Ellgaard L.

Biosci Rep. 2014 Apr 1;34(2). pii: e00103. Print 2014 Apr 1.


Cell biology of cysteine-based molecular switches.

Appenzeller-Herzog C, Inaba K, Delaunay-Moisan A.

Int J Cell Biol. 2014;2014:157038. doi: 10.1155/2014/157038. Epub 2014 Feb 6. No abstract available.


GPx8 peroxidase prevents leakage of H2O2 from the endoplasmic reticulum.

Ramming T, Hansen HG, Nagata K, Ellgaard L, Appenzeller-Herzog C.

Free Radic Biol Med. 2014 May;70:106-16. doi: 10.1016/j.freeradbiomed.2014.01.018. Epub 2014 Feb 22.


Erratum: Green fluorescent protein-based monitoring of endoplasmic reticulum redox poise.

Appenzeller-Herzog C, Birk J.

Front Genet. 2013 Nov 26;4:255. eCollection 2013.


Destroy and exploit: catalyzed removal of hydroperoxides from the endoplasmic reticulum.

Ramming T, Appenzeller-Herzog C.

Int J Cell Biol. 2013;2013:180906. doi: 10.1155/2013/180906. Epub 2013 Oct 24. Review.


Intracellular glutathione pools are heterogeneously concentrated.

Montero D, Tachibana C, Rahr Winther J, Appenzeller-Herzog C.

Redox Biol. 2013 Oct 28;1:508-13. doi: 10.1016/j.redox.2013.10.005. eCollection 2013.


Endoplasmic reticulum oxidoreductin-1α (Ero1α) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress.

Wright J, Birk J, Haataja L, Liu M, Ramming T, Weiss MA, Appenzeller-Herzog C, Arvan P.

J Biol Chem. 2013 Oct 25;288(43):31010-8. doi: 10.1074/jbc.M113.510065. Epub 2013 Sep 10.


Green fluorescent protein-based monitoring of endoplasmic reticulum redox poise.

Birk J, Ramming T, Odermatt A, Appenzeller-Herzog C.

Front Genet. 2013 Jun 13;4:108. doi: 10.3389/fgene.2013.00108. eCollection 2013. Erratum in: Front Genet. 2013 Nov 26;4:255.


Endoplasmic reticulum: reduced and oxidized glutathione revisited.

Birk J, Meyer M, Aller I, Hansen HG, Odermatt A, Dick TP, Meyer AJ, Appenzeller-Herzog C.

J Cell Sci. 2013 Apr 1;126(Pt 7):1604-17. doi: 10.1242/jcs.117218. Epub 2013 Feb 19.


Hyperactivity of the Ero1α oxidase elicits endoplasmic reticulum stress but no broad antioxidant response.

Hansen HG, Schmidt JD, Søltoft CL, Ramming T, Geertz-Hansen HM, Christensen B, Sørensen ES, Juncker AS, Appenzeller-Herzog C, Ellgaard L.

J Biol Chem. 2012 Nov 16;287(47):39513-23. doi: 10.1074/jbc.M112.405050. Epub 2012 Oct 1.


Suppression of the Nrf2-dependent antioxidant response by glucocorticoids and 11β-HSD1-mediated glucocorticoid activation in hepatic cells.

Kratschmar DV, Calabrese D, Walsh J, Lister A, Birk J, Appenzeller-Herzog C, Moulin P, Goldring CE, Odermatt A.

PLoS One. 2012;7(5):e36774. doi: 10.1371/journal.pone.0036774. Epub 2012 May 11.


Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling.

Appenzeller-Herzog C, Hall MN.

Trends Cell Biol. 2012 May;22(5):274-82. doi: 10.1016/j.tcb.2012.02.006. Epub 2012 Mar 21. Review.


The physiological functions of mammalian endoplasmic oxidoreductin 1: on disulfides and more.

Ramming T, Appenzeller-Herzog C.

Antioxid Redox Signal. 2012 May 15;16(10):1109-18. doi: 10.1089/ars.2011.4475. Epub 2012 Feb 15. Review.


Updates on "endoplasmic reticulum redox".

Appenzeller-Herzog C.

Antioxid Redox Signal. 2012 Apr 15;16(8):760-2. doi: 10.1089/ars.2011.4463. Epub 2012 Jan 13. No abstract available.


Glutathione- and non-glutathione-based oxidant control in the endoplasmic reticulum.

Appenzeller-Herzog C.

J Cell Sci. 2011 Mar 15;124(Pt 6):847-55. doi: 10.1242/jcs.080895.


Identification of the PDI-family member ERp90 as an interaction partner of ERFAD.

Riemer J, Hansen HG, Appenzeller-Herzog C, Johansson L, Ellgaard L.

PLoS One. 2011 Feb 16;6(2):e17037. doi: 10.1371/journal.pone.0017037.


Disulphide production by Ero1α-PDI relay is rapid and effectively regulated.

Appenzeller-Herzog C, Riemer J, Zito E, Chin KT, Ron D, Spiess M, Ellgaard L.

EMBO J. 2010 Oct 6;29(19):3318-29. doi: 10.1038/emboj.2010.203. Epub 2010 Aug 27.


A luminal flavoprotein in endoplasmic reticulum-associated degradation.

Riemer J, Appenzeller-Herzog C, Johansson L, Bodenmiller B, Hartmann-Petersen R, Ellgaard L.

Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14831-6. doi: 10.1073/pnas.0900742106. Epub 2009 Aug 19.


A novel disulphide switch mechanism in Ero1alpha balances ER oxidation in human cells.

Appenzeller-Herzog C, Riemer J, Christensen B, Sørensen ES, Ellgaard L.

EMBO J. 2008 Nov 19;27(22):2977-87. doi: 10.1038/emboj.2008.202. Epub 2008 Oct 2.


The human PDI family: versatility packed into a single fold.

Appenzeller-Herzog C, Ellgaard L.

Biochim Biophys Acta. 2008 Apr;1783(4):535-48. Epub 2007 Dec 3. Review.


The ER-Golgi intermediate compartment (ERGIC): in search of its identity and function.

Appenzeller-Herzog C, Hauri HP.

J Cell Sci. 2006 Jun 1;119(Pt 11):2173-83. Review.


Carbohydrate- and conformation-dependent cargo capture for ER-exit.

Appenzeller-Herzog C, Nyfeler B, Burkhard P, Santamaria I, Lopez-Otin C, Hauri HP.

Mol Biol Cell. 2005 Mar;16(3):1258-67. Epub 2005 Jan 5.


pH-induced conversion of the transport lectin ERGIC-53 triggers glycoprotein release.

Appenzeller-Herzog C, Roche AC, Nufer O, Hauri HP.

J Biol Chem. 2004 Mar 26;279(13):12943-50. Epub 2004 Jan 12.

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