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Items: 1 to 50 of 113

1.

Coordinate regulation of virulence and metabolic genes by the transcription factor HbhR in Mycobacterium marinum.

Raze D, Segers J, Mille C, Slupek S, Lecher S, Coutte L, Antoine R, Ducrocq L, Rouanet C, Appelmelk BJ, Locht C.

Mol Microbiol. 2020 Jan;113(1):52-67. doi: 10.1111/mmi.14400. Epub 2019 Oct 17.

PMID:
31587365
2.

Deciphering the molecular basis of mycobacteria and lipoglycan recognition by the C-type lectin Dectin-2.

Decout A, Silva-Gomes S, Drocourt D, Blattes E, Rivière M, Prandi J, Larrouy-Maumus G, Caminade AM, Hamasur B, Källenius G, Kaur D, Dobos KM, Lucas M, Sutcliffe IC, Besra GS, Appelmelk BJ, Gilleron M, Jackson M, Vercellone A, Tiraby G, Nigou J.

Sci Rep. 2018 Nov 15;8(1):16840. doi: 10.1038/s41598-018-35393-5.

3.

Inorganic Phosphate Limitation Modulates Capsular Polysaccharide Composition in Mycobacteria.

van de Weerd R, Boot M, Maaskant J, Sparrius M, Verboom T, van Leeuwen LM, Burggraaf MJ, Paauw NJ, Dainese E, Manganelli R, Bitter W, Appelmelk BJ, Geurtsen J.

J Biol Chem. 2016 May 27;291(22):11787-99. doi: 10.1074/jbc.M116.722454. Epub 2016 Apr 4.

4.

Human Milk Blocks DC-SIGN-Pathogen Interaction via MUC1.

Koning N, Kessen SF, Van Der Voorn JP, Appelmelk BJ, Jeurink PV, Knippels LM, Garssen J, Van Kooyk Y.

Front Immunol. 2015 Mar 13;6:112. doi: 10.3389/fimmu.2015.00112. eCollection 2015.

5.

A murine monoclonal antibody to glycogen: characterization of epitope-fine specificity by saturation transfer difference (STD) NMR spectroscopy and its use in mycobacterial capsular α-glucan research.

van de Weerd R, Berbís MA, Sparrius M, Maaskant JJ, Boot M, Paauw NJ, de Vries N, Boon L, Baba O, Cañada FJ, Geurtsen J, Jiménez-Barbero J, Appelmelk BJ.

Chembiochem. 2015 Apr 13;16(6):977-89. doi: 10.1002/cbic.201402713. Epub 2015 Mar 12.

PMID:
25766777
6.

Structure and function of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo.

Romano M, van de Weerd R, Brouwer FC, Roviello GN, Lacroix R, Sparrius M, van den Brink-van Stempvoort G, Maaskant JJ, van der Sar AM, Appelmelk BJ, Geurtsen JJ, Berisio R.

Structure. 2014 May 6;22(5):719-30. doi: 10.1016/j.str.2014.01.014. Epub 2014 Apr 3.

7.

Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity.

Stoop EJ, Mishra AK, Driessen NN, van Stempvoort G, Bouchier P, Verboom T, van Leeuwen LM, Sparrius M, Raadsen SA, van Zon M, van der Wel NN, Besra GS, Geurtsen J, Bitter W, Appelmelk BJ, van der Sar AM.

Cell Microbiol. 2013 Dec;15(12):2093-108. doi: 10.1111/cmi.12175. Epub 2013 Aug 22.

8.

Lipoarabinomannan mannose caps do not affect mycobacterial virulence or the induction of protective immunity in experimental animal models of infection and have minimal impact on in vitro inflammatory responses.

Afonso-Barroso A, Clark SO, Williams A, Rosa GT, Nóbrega C, Silva-Gomes S, Vale-Costa S, Ummels R, Stoker N, Movahedzadeh F, van der Ley P, Sloots A, Cot M, Appelmelk BJ, Puzo G, Nigou J, Geurtsen J, Appelberg R.

Cell Microbiol. 2013 Apr;15(4):660-74. doi: 10.1111/cmi.12065. Epub 2012 Nov 21.

PMID:
23121245
9.

Cyanovirin-N inhibits mannose-dependent Mycobacterium-C-type lectin interactions but does not protect against murine tuberculosis.

Driessen NN, Boshoff HI, Maaskant JJ, Gilissen SA, Vink S, van der Sar AM, Vandenbroucke-Grauls CM, Bewley CA, Appelmelk BJ, Geurtsen J.

J Immunol. 2012 Oct 1;189(7):3585-92. Epub 2012 Aug 31.

10.

ESX-5-deficient Mycobacterium marinum is hypervirulent in adult zebrafish.

Weerdenburg EM, Abdallah AM, Mitra S, de Punder K, van der Wel NN, Bird S, Appelmelk BJ, Bitter W, van der Sar AM.

Cell Microbiol. 2012 May;14(5):728-39. doi: 10.1111/j.1462-5822.2012.01755.x. Epub 2012 Feb 15.

PMID:
22256857
11.

Lipoarabinomannan and related glycoconjugates: structure, biogenesis and role in Mycobacterium tuberculosis physiology and host-pathogen interaction.

Mishra AK, Driessen NN, Appelmelk BJ, Besra GS.

FEMS Microbiol Rev. 2011 Nov;35(6):1126-57. doi: 10.1111/j.1574-6976.2011.00276.x. Epub 2011 May 31. Review.

12.

Gastric Autoimmunity.

Bergman MP, Faller G, D'Elios MM, Del Prete G, Vandenbroucke-Grauls CMJE, Appelmelk BJ.

In: Mobley HLT, Mendz GL, Hazell SL, editors. Helicobacter pylori: Physiology and Genetics. Washington (DC): ASM Press; 2001. Chapter 36.

13.

Lipopolysaccharide Lewis Antigens.

Appelmelk BJ, Vandenbroucke-Grauls CMJE.

In: Mobley HLT, Mendz GL, Hazell SL, editors. Helicobacter pylori: Physiology and Genetics. Washington (DC): ASM Press; 2001. Chapter 35.

14.

Mycobacterium marinum MMAR_2380, a predicted transmembrane acyltransferase, is essential for the presence of the mannose cap on lipoarabinomannan.

Driessen NN, Stoop EJM, Ummels R, Gurcha SS, Mishra AK, Larrouy-Maumus G, Nigou J, Gilleron M, Puzo G, Maaskant JJ, Sparrius M, Besra GS, Bitter W, Vandenbroucke-Grauls CMJE, Appelmelk BJ.

Microbiology. 2010 Nov;156(Pt 11):3492-3502. doi: 10.1099/mic.0.037507-0. Epub 2010 Aug 5.

15.

Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins.

Sani M, Houben EN, Geurtsen J, Pierson J, de Punder K, van Zon M, Wever B, Piersma SR, Jiménez CR, Daffé M, Appelmelk BJ, Bitter W, van der Wel N, Peters PJ.

PLoS Pathog. 2010 Mar 5;6(3):e1000794. doi: 10.1371/journal.ppat.1000794.

16.

A truncated lipoglycan from mycobacteria with altered immunological properties.

Birch HL, Alderwick LJ, Appelmelk BJ, Maaskant J, Bhatt A, Singh A, Nigou J, Eggeling L, Geurtsen J, Besra GS.

Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2634-9. doi: 10.1073/pnas.0915082107. Epub 2010 Jan 25.

17.

Identification of mycobacterial alpha-glucan as a novel ligand for DC-SIGN: involvement of mycobacterial capsular polysaccharides in host immune modulation.

Geurtsen J, Chedammi S, Mesters J, Cot M, Driessen NN, Sambou T, Kakutani R, Ummels R, Maaskant J, Takata H, Baba O, Terashima T, Bovin N, Vandenbroucke-Grauls CM, Nigou J, Puzo G, Lemassu A, Daffé M, Appelmelk BJ.

J Immunol. 2009 Oct 15;183(8):5221-31. doi: 10.4049/jimmunol.0900768. Epub 2009 Sep 25.

18.

Type VII secretion in mycobacteria: classification in line with cell envelope structure.

Bitter W, Houben EN, Luirink J, Appelmelk BJ.

Trends Microbiol. 2009 Aug;17(8):337-8. doi: 10.1016/j.tim.2009.05.007. Epub 2009 Aug 5. No abstract available.

PMID:
19660950
19.

Role of phosphatidylinositol mannosides in the interaction between mycobacteria and DC-SIGN.

Driessen NN, Ummels R, Maaskant JJ, Gurcha SS, Besra GS, Ainge GD, Larsen DS, Painter GF, Vandenbroucke-Grauls CM, Geurtsen J, Appelmelk BJ.

Infect Immun. 2009 Oct;77(10):4538-47. doi: 10.1128/IAI.01256-08. Epub 2009 Aug 3.

20.

PPE and PE_PGRS proteins of Mycobacterium marinum are transported via the type VII secretion system ESX-5.

Abdallah AM, Verboom T, Weerdenburg EM, Gey van Pittius NC, Mahasha PW, Jiménez C, Parra M, Cadieux N, Brennan MJ, Appelmelk BJ, Bitter W.

Mol Microbiol. 2009 Aug;73(3):329-40. doi: 10.1111/j.1365-2958.2009.06783.x. Epub 2009 Jul 7.

21.

Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.

Dunlop DC, Ulrich A, Appelmelk BJ, Burton DR, Dwek RA, Zitzmann N, Scanlan CN.

AIDS. 2008 Oct 18;22(16):2214-7. doi: 10.1097/QAD.0b013e328314b5df.

PMID:
18832887
22.

The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction.

Appelmelk BJ, den Dunnen J, Driessen NN, Ummels R, Pak M, Nigou J, Larrouy-Maumus G, Gurcha SS, Movahedzadeh F, Geurtsen J, Brown EJ, Eysink Smeets MM, Besra GS, Willemsen PT, Lowary TL, van Kooyk Y, Maaskant JJ, Stoker NG, van der Ley P, Puzo G, Vandenbroucke-Grauls CM, Wieland CW, van der Poll T, Geijtenbeek TB, van der Sar AM, Bitter W.

Cell Microbiol. 2008 Apr;10(4):930-44. Epub 2007 Dec 5.

PMID:
18070119
23.

Type VII secretion--mycobacteria show the way.

Abdallah AM, Gey van Pittius NC, Champion PA, Cox J, Luirink J, Vandenbroucke-Grauls CM, Appelmelk BJ, Bitter W.

Nat Rev Microbiol. 2007 Nov;5(11):883-91.

PMID:
17922044
24.

A specific secretion system mediates PPE41 transport in pathogenic mycobacteria.

Abdallah AM, Verboom T, Hannes F, Safi M, Strong M, Eisenberg D, Musters RJ, Vandenbroucke-Grauls CM, Appelmelk BJ, Luirink J, Bitter W.

Mol Microbiol. 2006 Nov;62(3):667-79.

25.

Variations in Helicobacter pylori lipopolysaccharide to evade the innate immune component surfactant protein D.

Khamri W, Moran AP, Worku ML, Karim QN, Walker MM, Annuk H, Ferris JA, Appelmelk BJ, Eggleton P, Reid KB, Thursz MR.

Infect Immun. 2005 Nov;73(11):7677-86.

26.

Carbohydrate specificities of the murine DC-SIGN homologue mSIGNR1.

Koppel EA, Ludwig IS, Appelmelk BJ, van Kooyk Y, Geijtenbeek TB.

Immunobiology. 2005;210(2-4):195-201.

PMID:
16164026
27.

A multiplexed and miniaturized serological tuberculosis assay identifies antigens that discriminate maximally between TB and non-TB sera.

Tong M, Jacobi CE, van de Rijke FM, Kuijper S, van de Werken S, Lowary TL, Hokke CH, Appelmelk BJ, Nagelkerke NJ, Tanke HJ, van Gijlswijk RP, Veuskens J, Kolk AH, Raap AK.

J Immunol Methods. 2005 Jun;301(1-2):154-63.

PMID:
15979638
28.

Long-term acid suppression by omeprazole in gastro-oesophageal reflux disease patients does not lead to anti-gastric autoantibody production.

Bergman MP, Klinkenberg-Knol EC, Faller G, Aar A, Lakhai W, Vandenbroucke-Grauls CM, Kuipers EJ, Appelmelk BJ.

Aliment Pharmacol Ther. 2005 Apr 15;21(8):977-83.

29.

Molecular specificity and functional properties of autoreactive T-cell response in human gastric autoimmunity.

D'Elios MM, Amedei A, Azzurri A, Benagiano M, Del Prete G, Bergman MP, Vandenbroucke-Grauls CM, Appelmelk BJ.

Int Rev Immunol. 2005 Jan-Apr;24(1-2):111-22. Review.

PMID:
15763992
30.

The story so far: Helicobacter pylori and gastric autoimmunity.

Bergman MP, Vandenbroucke-Grauls CM, Appelmelk BJ, D'Elios MM, Amedei A, Azzurri A, Benagiano M, Del Prete G.

Int Rev Immunol. 2005 Jan-Apr;24(1-2):63-91. Review.

PMID:
15763990
31.

Helicobacter pylori and gastric autoimmunity.

D'Elios MM, Bergman MP, Amedei A, Appelmelk BJ, Del Prete G.

Microbes Infect. 2004 Dec;6(15):1395-401. Review.

PMID:
15596126
32.

Helicobacter pylori modulates the T helper cell 1/T helper cell 2 balance through phase-variable interaction between lipopolysaccharide and DC-SIGN.

Bergman MP, Engering A, Smits HH, van Vliet SJ, van Bodegraven AA, Wirth HP, Kapsenberg ML, Vandenbroucke-Grauls CM, van Kooyk Y, Appelmelk BJ.

J Exp Med. 2004 Oct 18;200(8):979-90.

33.

Identification of the mycobacterial carbohydrate structure that binds the C-type lectins DC-SIGN, L-SIGN and SIGNR1.

Koppel EA, Ludwig IS, Hernandez MS, Lowary TL, Gadikota RR, Tuzikov AB, Vandenbroucke-Grauls CM, van Kooyk Y, Appelmelk BJ, Geijtenbeek TB.

Immunobiology. 2004;209(1-2):117-27.

PMID:
15481146
34.

A star with stripes: zebrafish as an infection model.

van der Sar AM, Appelmelk BJ, Vandenbroucke-Grauls CM, Bitter W.

Trends Microbiol. 2004 Oct;12(10):451-7. Review. No abstract available.

PMID:
15381194
35.

Gastric autoimmunity: the role of Helicobacter pylori and molecular mimicry.

D'Elios MM, Appelmelk BJ, Amedei A, Bergman MP, Del Prete G.

Trends Mol Med. 2004 Jul;10(7):316-23. Review.

PMID:
15242679
36.

Molecular mimicry between Helicobacter pylori antigens and H+, K+ --adenosine triphosphatase in human gastric autoimmunity.

Amedei A, Bergman MP, Appelmelk BJ, Azzurri A, Benagiano M, Tamburini C, van der Zee R, Telford JL, Vandenbroucke-Grauls CM, D'Elios MM, Del Prete G.

J Exp Med. 2003 Oct 20;198(8):1147-56.

37.

Zebrafish embryos as a model host for the real time analysis of Salmonella typhimurium infections.

van der Sar AM, Musters RJ, van Eeden FJ, Appelmelk BJ, Vandenbroucke-Grauls CM, Bitter W.

Cell Microbiol. 2003 Sep;5(9):601-11.

PMID:
12925130
38.

Limited role of lipopolysaccharide Lewis antigens in adherence of Helicobacter pylori to the human gastric epithelium.

Mahdavi J, Borén T, Vandenbroucke-Grauls C, Appelmelk BJ.

Infect Immun. 2003 May;71(5):2876-80.

39.

Characterization of H+,K+-ATPase T cell epitopes in human autoimmune gastritis.

Bergman MP, Amedei A, D'Elios MM, Azzurri A, Benagiano M, Tamburini C, van der Zee R, Vandenbroucke-Grauls CM, Appelmelk BJ, Del Prete G.

Eur J Immunol. 2003 Feb;33(2):539-45. Erratum in: Eur J Immunol. 2003 Apr;33(4):1139.

40.

Cutting edge: carbohydrate profiling identifies new pathogens that interact with dendritic cell-specific ICAM-3-grabbing nonintegrin on dendritic cells.

Appelmelk BJ, van Die I, van Vliet SJ, Vandenbroucke-Grauls CM, Geijtenbeek TB, van Kooyk Y.

J Immunol. 2003 Feb 15;170(4):1635-9.

41.

Phase variation in the Helicobacter pylori phospholipase A gene and its role in acid adaptation.

Tannaes T, Dekker N, Bukholm G, Bijlsma JJ, Appelmelk BJ.

Infect Immun. 2001 Dec;69(12):7334-40.

42.

[Adjuvant therapies for sepsis and shock: which are more effective?].

Groeneveld AB, Beishuizen A, Appelmelk BJ, Girbes AR.

Ned Tijdschr Geneeskd. 2001 Sep 8;145(36):1718-22. Review. Dutch.

PMID:
11572169
43.

Helicobacter pylori from asymptomatic hosts expressing heptoglycan but lacking Lewis O-chains: Lewis blood-group O-chains may play a role in Helicobacter pylori induced pathology.

Monteiro MA, St Michael F, Rasko DA, Taylor DE, Conlan JW, Chan KH, Logan SM, Appelmelk BJ, Perry MB.

Biochem Cell Biol. 2001;79(4):449-59.

PMID:
11527214
44.

The role of Helicobacter pylori virulence factors in interleukin production by monocytic cells.

de Jonge R, Kusters JG, Timmer MS, Gimmel V, Appelmelk BJ, Bereswill S, van Vliet AH, Meuwissen SG, Kist M, Vandenbroucke-Grauls CM, Kuipers EJ.

FEMS Microbiol Lett. 2001 Mar 15;196(2):235-8.

45.

Antigastric autoantibodies in ferrets naturally infected with Helicobacter mustelae.

Cróinín TO, Clyne M, Appelmelk BJ, Drumm B.

Infect Immun. 2001 Apr;69(4):2708-13.

46.

H. pylori adhesion and Lewis X.

Martin SL, McColm AA, Appelmelk BJ.

Gastroenterology. 2000 Nov;119(5):1414-6. No abstract available.

PMID:
11185463
47.

H(+),K(+)-atpase (proton pump) is the target autoantigen of Th1-type cytotoxic T cells in autoimmune gastritis.

D'Elios MM, Bergman MP, Azzurri A, Amedei A, Benagiano M, De Pont JJ, Cianchi F, Vandenbroucke-Grauls CM, Romagnani S, Appelmelk BJ, Del Prete G.

Gastroenterology. 2001 Feb;120(2):377-86.

PMID:
11159878
48.

Why Helicobacter pylori has Lewis antigens.

Appelmelk BJ, Monteiro MA, Martin SL, Moran AP, Vandenbroucke-Grauls CM.

Trends Microbiol. 2000 Dec;8(12):565-70. Review.

PMID:
11115753
49.

Phase variation in H type I and Lewis a epitopes of Helicobacter pylori lipopolysaccharide.

Appelmelk BJ, Martino MC, Veenhof E, Monteiro MA, Maaskant JJ, Negrini R, Lindh F, Perry M, Del Giudice G, Vandenbroucke-Grauls CM.

Infect Immun. 2000 Oct;68(10):5928-32. Erratum in: Infect Immun 2000 Dec;68(12):7214.

50.

H pylori and Lewis antigens.

Appelmelk BJ, Vandenbroucke-Grauls CM.

Gut. 2000 Jul;47(1):10-1. No abstract available.

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