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Items: 32

1.

A Biocompatible Therapeutic Catheter-Deliverable Hydrogel for In Situ Tissue Engineering.

Steele AN, Stapleton LM, Farry JM, Lucian HJ, Paulsen MJ, Eskandari A, Hironaka CE, Thakore AD, Wang H, Yu AC, Chan D, Appel EA, Woo YJ.

Adv Healthc Mater. 2019 Mar;8(5):e1801147. doi: 10.1002/adhm.201801147. Epub 2019 Feb 4.

PMID:
30714355
2.

Non-Newtonian Polymer-Nanoparticle Hydrogels Enhance Cell Viability during Injection.

Lopez Hernandez H, Grosskopf AK, Stapleton LM, Agmon G, Appel EA.

Macromol Biosci. 2019 Jan;19(1):e1800275. doi: 10.1002/mabi.201800275. Epub 2018 Oct 22.

PMID:
30369048
3.

Supramolecular polymeric biomaterials.

Mann JL, Yu AC, Agmon G, Appel EA.

Biomater Sci. 2017 Dec 19;6(1):10-37. doi: 10.1039/c7bm00780a. Review.

PMID:
29164196
4.

Engineering the Mechanical Properties of Polymer Networks with Precise Doping of Primary Defects.

Chan D, Ding Y, Dauskardt RH, Appel EA.

ACS Appl Mater Interfaces. 2017 Dec 6;9(48):42217-42224. doi: 10.1021/acsami.7b14376. Epub 2017 Nov 22.

PMID:
29135222
5.

Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics.

Bertrand N, Grenier P, Mahmoudi M, Lima EM, Appel EA, Dormont F, Lim JM, Karnik R, Langer R, Farokhzad OC.

Nat Commun. 2017 Oct 3;8(1):777. doi: 10.1038/s41467-017-00600-w.

6.

Synthesis and Biological Evaluation of Ionizable Lipid Materials for the In Vivo Delivery of Messenger RNA to B Lymphocytes.

Fenton OS, Kauffman KJ, Kaczmarek JC, McClellan RL, Jhunjhunwala S, Tibbitt MW, Zeng MD, Appel EA, Dorkin JR, Mir FF, Yang JH, Oberli MA, Heartlein MW, DeRosa F, Langer R, Anderson DG.

Adv Mater. 2017 Sep;29(33). doi: 10.1002/adma.201606944. Epub 2017 Jul 6.

PMID:
28681930
7.

Decoupled Associative and Dissociative Processes in Strong yet Highly Dynamic Host-Guest Complexes.

Appel EA, Biedermann F, Hoogland D, Del Barrio J, Driscoll MD, Hay S, Wales DJ, Scherman OA.

J Am Chem Soc. 2017 Sep 20;139(37):12985-12993. doi: 10.1021/jacs.7b04821. Epub 2017 Sep 8.

PMID:
28661667
8.

Mixed Reversible Covalent Crosslink Kinetics Enable Precise, Hierarchical Mechanical Tuning of Hydrogel Networks.

Yesilyurt V, Ayoob AM, Appel EA, Borenstein JT, Langer R, Anderson DG.

Adv Mater. 2017 May;29(19). doi: 10.1002/adma.201605947. Epub 2017 Mar 15.

PMID:
28295624
9.

Single-Chain Polymeric Nanocarriers: A Platform for Determining Structure-Function Correlations in the Delivery of Molecular Cargo.

Chan D, Yu AC, Appel EA.

Biomacromolecules. 2017 Apr 10;18(4):1434-1439. doi: 10.1021/acs.biomac.7b00249. Epub 2017 Mar 17.

PMID:
28263572
10.

Scalable manufacturing of biomimetic moldable hydrogels for industrial applications.

Yu AC, Chen H, Chan D, Agmon G, Stapleton LM, Sevit AM, Tibbitt MW, Acosta JD, Zhang T, Franzia PW, Langer R, Appel EA.

Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14255-14260. Epub 2016 Nov 28.

11.

Supramolecular PEGylation of biopharmaceuticals.

Webber MJ, Appel EA, Vinciguerra B, Cortinas AB, Thapa LS, Jhunjhunwala S, Isaacs L, Langer R, Anderson DG.

Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14189-14194. Epub 2016 Nov 28.

12.

Injectable and Glucose-Responsive Hydrogels Based on Boronic Acid-Glucose Complexation.

Dong Y, Wang W, Veiseh O, Appel EA, Xue K, Webber MJ, Tang BC, Yang XW, Weir GC, Langer R, Anderson DG.

Langmuir. 2016 Aug 30;32(34):8743-7. doi: 10.1021/acs.langmuir.5b04755. Epub 2016 Aug 17.

13.

Bioinspired Alkenyl Amino Alcohol Ionizable Lipid Materials for Highly Potent In Vivo mRNA Delivery.

Fenton OS, Kauffman KJ, McClellan RL, Appel EA, Dorkin JR, Tibbitt MW, Heartlein MW, DeRosa F, Langer R, Anderson DG.

Adv Mater. 2016 Apr 20;28(15):2939-43. doi: 10.1002/adma.201505822. Epub 2016 Feb 18.

14.

Supramolecular biomaterials.

Webber MJ, Appel EA, Meijer EW, Langer R.

Nat Mater. 2016 Jan;15(1):13-26. doi: 10.1038/nmat4474. Review.

PMID:
26681596
15.

Injectable Self-Healing Glucose-Responsive Hydrogels with pH-Regulated Mechanical Properties.

Yesilyurt V, Webber MJ, Appel EA, Godwin C, Langer R, Anderson DG.

Adv Mater. 2016 Jan 6;28(1):86-91. doi: 10.1002/adma.201502902. Epub 2015 Nov 5.

16.

Formation of Cucurbit[8]uril-Based Supramolecular Hydrogel Beads Using Droplet-Based Microfluidics.

Xu X, Appel EA, Liu X, Parker RM, Scherman OA, Abell C.

Biomacromolecules. 2015 Sep 14;16(9):2743-9. doi: 10.1021/acs.biomac.5b01048. Epub 2015 Aug 28.

PMID:
26256409
17.

Self-assembled hydrogels utilizing polymer-nanoparticle interactions.

Appel EA, Tibbitt MW, Webber MJ, Mattix BA, Veiseh O, Langer R.

Nat Commun. 2015 Feb 19;6:6295. doi: 10.1038/ncomms7295.

18.

Non-cell-adhesive substrates for printing of arrayed biomaterials.

Appel EA, Larson BL, Luly KM, Kim JD, Langer R.

Adv Healthc Mater. 2015 Mar 11;4(4):501-5. doi: 10.1002/adhm.201400594. Epub 2014 Nov 27.

19.

The control of cargo release from physically crosslinked hydrogels by crosslink dynamics.

Appel EA, Forster RA, Rowland MJ, Scherman OA.

Biomaterials. 2014 Dec;35(37):9897-9903. doi: 10.1016/j.biomaterials.2014.08.001. Epub 2014 Sep 16.

PMID:
25239043
20.

Activation energies control the macroscopic properties of physically cross-linked materials.

Appel EA, Forster RA, Koutsioubas A, Toprakcioglu C, Scherman OA.

Angew Chem Int Ed Engl. 2014 Sep 15;53(38):10038-43. doi: 10.1002/anie.201403192. Epub 2014 Jul 23.

PMID:
25056596
21.

Gluing gels: A nanoparticle solution.

Appel EA, Scherman OA.

Nat Mater. 2014 Mar;13(3):231-2. doi: 10.1038/nmat3893. No abstract available.

PMID:
24553651
22.

Enhanced stability and activity of temozolomide in primary glioblastoma multiforme cells with cucurbit[n]uril.

Appel EA, Rowland MJ, Loh XJ, Heywood RM, Watts C, Scherman OA.

Chem Commun (Camb). 2012 Oct 11;48(79):9843-5. doi: 10.1039/c2cc35131e. Epub 2012 Aug 30.

PMID:
22936104
23.

Supramolecular polymeric hydrogels.

Appel EA, del Barrio J, Loh XJ, Scherman OA.

Chem Soc Rev. 2012 Sep 21;41(18):6195-214. doi: 10.1039/c2cs35264h. Epub 2012 Aug 13.

PMID:
22890548
24.

Ultrahigh-water-content supramolecular hydrogels exhibiting multistimuli responsiveness.

Appel EA, Loh XJ, Jones ST, Biedermann F, Dreiss CA, Scherman OA.

J Am Chem Soc. 2012 Jul 18;134(28):11767-73. doi: 10.1021/ja3044568. Epub 2012 Jul 3.

PMID:
22758793
25.

Toward biodegradable nanogel star polymers via organocatalytic ROP.

Appel EA, Lee VY, Nguyen TT, McNeil M, Nederberg F, Hedrick JL, Swope WC, Rice JE, Miller RD, Sly J.

Chem Commun (Camb). 2012 Jun 21;48(49):6163-5. doi: 10.1039/c2cc31406a. Epub 2012 May 16.

PMID:
22590707
26.

Sustained release of proteins from high water content supramolecular polymer hydrogels.

Appel EA, Loh XJ, Jones ST, Dreiss CA, Scherman OA.

Biomaterials. 2012 Jun;33(18):4646-52. doi: 10.1016/j.biomaterials.2012.02.030. Epub 2012 Mar 27.

PMID:
22459194
27.

Formation of single-chain polymer nanoparticles in water through host-guest interactions.

Appel EA, Dyson J, del Barrio J, Walsh Z, Scherman OA.

Angew Chem Int Ed Engl. 2012 Apr 23;51(17):4185-9. doi: 10.1002/anie.201108659. Epub 2012 Mar 15. No abstract available.

PMID:
22422662
28.

Triply triggered doxorubicin release from supramolecular nanocontainers.

Loh XJ, del Barrio J, Toh PP, Lee TC, Jiao D, Rauwald U, Appel EA, Scherman OA.

Biomacromolecules. 2012 Jan 9;13(1):84-91. doi: 10.1021/bm201588m. Epub 2011 Dec 23.

PMID:
22148638
29.

Supramolecular cross-linked networks via host-guest complexation with cucurbit[8]uril.

Appel EA, Biedermann F, Rauwald U, Jones ST, Zayed JM, Scherman OA.

J Am Chem Soc. 2010 Oct 13;132(40):14251-60. doi: 10.1021/ja106362w.

PMID:
20845973
30.

Supramolecular gold nanoparticle-polymer composites formed in water with cucurbit[8]uril.

Coulston RJ, Jones ST, Lee TC, Appel EA, Scherman OA.

Chem Commun (Camb). 2011 Jan 7;47(1):164-6. doi: 10.1039/c0cc03250f. Epub 2010 Sep 14.

PMID:
20842297
31.

Hierarchical supermolecular structures for sustained drug release.

Tan JP, Kim SH, Nederberg F, Appel EA, Waymouth RM, Zhang Y, Hedrick JL, Yang YY.

Small. 2009 Jul;5(13):1504-7. doi: 10.1002/smll.200801756. No abstract available.

PMID:
19326354
32.

Does Arizona really need more physicians?

King BF, Appel EA, Hedgecock D.

Ariz Med. 1985 Mar;42(3):169-74. No abstract available.

PMID:
3994535

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