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Items: 1 to 20 of 48


Rewiring E2F1 with classical NHEJ via APLF suppression promotes bladder cancer invasiveness.

Richter C, Marquardt S, Li F, Spitschak A, Murr N, Edelhäuser BAH, Iliakis G, Pützer BM, Logotheti S.

J Exp Clin Cancer Res. 2019 Jul 8;38(1):292. doi: 10.1186/s13046-019-1286-9.


Downregulation of Transcription Factor T-Bet as a Protective Strategy in Monosodium Urate-Induced Gouty Inflammation.

Yang QB, He YL, Zhang QB, Mi QS, Zhou JG.

Front Immunol. 2019 May 29;10:1199. doi: 10.3389/fimmu.2019.01199. eCollection 2019.


Genetic and epigenetic profiling of the infertile male.

Cheung S, Parrella A, Rosenwaks Z, Palermo GD.

PLoS One. 2019 Mar 21;14(3):e0214275. doi: 10.1371/journal.pone.0214275. eCollection 2019.


Evolutionary diversity and novelty of DNA repair genes in asexual Bdelloid rotifers.

Hecox-Lea BJ, Mark Welch DB.

BMC Evol Biol. 2018 Nov 28;18(1):177. doi: 10.1186/s12862-018-1288-9.


XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.

Nemoz C, Ropars V, Frit P, Gontier A, Drevet P, Yu J, Guerois R, Pitois A, Comte A, Delteil C, Barboule N, Legrand P, Baconnais S, Yin Y, Tadi S, Barbet-Massin E, Berger I, Le Cam E, Modesti M, Rothenberg E, Calsou P, Charbonnier JB.

Nat Struct Mol Biol. 2018 Oct;25(10):971-980. doi: 10.1038/s41594-018-0133-6. Epub 2018 Oct 5.


Microscale Thermophoresis Analysis of Chromatin Interactions.

Corbeski I, Horn V, van der Valk RA, le Paige UB, Dame RT, van Ingen H.

Methods Mol Biol. 2018;1837:177-197. doi: 10.1007/978-1-4939-8675-0_11.


PARP2 mediates branched poly ADP-ribosylation in response to DNA damage.

Chen Q, Kassab MA, Dantzer F, Yu X.

Nat Commun. 2018 Aug 13;9(1):3233. doi: 10.1038/s41467-018-05588-5.


DNA repair factor APLF acts as a H2A-H2B histone chaperone through binding its DNA interaction surface.

Corbeski I, Dolinar K, Wienk H, Boelens R, van Ingen H.

Nucleic Acids Res. 2018 Aug 21;46(14):7138-7152. doi: 10.1093/nar/gky507.


Correction: Histone chaperone APLF regulates induction of pluripotency in murine fibroblasts (doi:10.1242/jcs.194035).

Syed KM, Joseph S, Mukherjee A, Majumder A, Teixeira JM, Dutta D, Pillai MR.

J Cell Sci. 2018 Apr 19;131(8). pii: jcs218842. doi: 10.1242/jcs.218842. No abstract available.


Enhanced expression of histone chaperone APLF associate with breast cancer.

Majumder A, Syed KM, Mukherjee A, Lankadasari MB, Azeez JM, Sreeja S, Harikumar KB, Pillai MR, Dutta D.

Mol Cancer. 2018 Mar 26;17(1):76. doi: 10.1186/s12943-018-0826-9.


Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications.

Kim K, Pedersen LC, Kirby TW, DeRose EF, London RE.

Nucleic Acids Res. 2017 Dec 1;45(21):12374-12387. doi: 10.1093/nar/gkx941.


Spinal Fusion for Pediatric Spondylolisthesis: National Trends, Complications, and Short-Term Outcomes.

Rumalla K, Yarbrough CK, Pugely AJ, Dorward IG.

Neurosurgery. 2018 May 1;82(5):701-709. doi: 10.1093/neuros/nyx295.


Germline whole exome sequencing and large-scale replication identifies FANCM as a likely high grade serous ovarian cancer susceptibility gene.

Dicks E, Song H, Ramus SJ, Oudenhove EV, Tyrer JP, Intermaggio MP, Kar S, Harrington P, Bowtell DD, Group AS, Cicek MS, Cunningham JM, Fridley BL, Alsop J, Jimenez-Linan M, Piskorz A, Goranova T, Kent E, Siddiqui N, Paul J, Crawford R, Poblete S, Lele S, Sucheston-Campbell L, Moysich KB, Sieh W, McGuire V, Lester J, Odunsi K, Whittemore AS, Bogdanova N, Dürst M, Hillemanns P, Karlan BY, Gentry-Maharaj A, Menon U, Tischkowitz M, Levine D, Brenton JD, Dörk T, Goode EL, Gayther SA, Pharoah DPP.

Oncotarget. 2017 Mar 3;8(31):50930-50940. doi: 10.18632/oncotarget.15871. eCollection 2017 Aug 1.


An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex.

Hammel M, Yu Y, Radhakrishnan SK, Chokshi C, Tsai MS, Matsumoto Y, Kuzdovich M, Remesh SG, Fang S, Tomkinson AE, Lees-Miller SP, Tainer JA.

J Biol Chem. 2016 Dec 30;291(53):26987-27006. doi: 10.1074/jbc.M116.751867. Epub 2016 Nov 14.


Histone chaperone APLF regulates induction of pluripotency in murine fibroblasts.

Syed KM, Joseph S, Mukherjee A, Majumder A, Teixeira JM, Dutta D, Pillai MR.

J Cell Sci. 2016 Dec 15;129(24):4576-4591. Epub 2016 Nov 14. Erratum in: J Cell Sci. 2018 Apr 19;131(8):.


Attenuated DNA damage repair delays therapy-related myeloid neoplasms in a mouse model.

Tong KI, Ota K, Komuro A, Ueda T, Ito A, Anne Koch C, Okada H.

Cell Death Dis. 2016 Oct 6;7(10):e2401. doi: 10.1038/cddis.2016.298.


The role of ADP-ribosylation in regulating DNA interstrand crosslink repair.

Gunn AR, Banos-Pinero B, Paschke P, Sanchez-Pulido L, Ariza A, Day J, Emrich M, Leys D, Ponting CP, Ahel I, Lakin ND.

J Cell Sci. 2016 Oct 15;129(20):3845-3858. Epub 2016 Sep 1.


End-processing nucleases and phosphodiesterases: An elite supporting cast for the non-homologous end joining pathway of DNA double-strand break repair.

Menon V, Povirk LF.

DNA Repair (Amst). 2016 Jul;43:57-68. doi: 10.1016/j.dnarep.2016.05.011. Epub 2016 May 18. Review.


The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins.

Grundy GJ, Rulten SL, Arribas-Bosacoma R, Davidson K, Kozik Z, Oliver AW, Pearl LH, Caldecott KW.

Nat Commun. 2016 Apr 11;7:11242. doi: 10.1038/ncomms11242.


Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains.

Cherry AL, Nott TJ, Kelly G, Rulten SL, Caldecott KW, Smerdon SJ.

DNA Repair (Amst). 2015 Nov;35:116-25. doi: 10.1016/j.dnarep.2015.10.002. Epub 2015 Oct 23.

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