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Items: 1 to 50 of 316

1.

Nontypeable Haemophilus influenzae Has Evolved Preferential Use of N-Acetylneuraminic Acid as a Host Adaptation.

Ng PSK, Day CJ, Atack JM, Hartley-Tassell LE, Winter LE, Marshanski T, Padler-Karavani V, Varki A, Barenkamp SJ, Apicella MA, Jennings MP.

MBio. 2019 May 7;10(3). pii: e00422-19. doi: 10.1128/mBio.00422-19.

2.

Commensal Bacteria: Not Just Innocent Bystanders.

Apicella MA.

MBio. 2019 Jan 15;10(1). pii: e02723-18. doi: 10.1128/mBio.02723-18.

3.

Molecular characterization of the interaction of sialic acid with the periplasmic binding protein from Haemophilus ducreyi.

Gangi Setty T, Mowers JC, Hobbs AG, Maiya SP, Syed S, Munson RS Jr, Apicella MA, Subramanian R.

J Biol Chem. 2018 Dec 28;293(52):20073-20084. doi: 10.1074/jbc.RA118.005151. Epub 2018 Oct 12.

PMID:
30315109
4.

Prenatal diagnosis, natural history, postnatal treatment and outcome of 222 cases of spina bifida: experience of a tertiary center.

Masini L, De Luca C, Noia G, Caruso A, Lanzone A, Rendeli C, Ausili E, Massimi L, Tamburrini G, Apicella M, De Santis M.

Ultrasound Obstet Gynecol. 2019 Mar;53(3):302-308. doi: 10.1002/uog.20136. Epub 2019 Feb 11.

PMID:
30288814
5.

Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies.

Apicella M, Giannoni E, Fiore S, Ferrari KJ, Fernández-Pérez D, Isella C, Granchi C, Minutolo F, Sottile A, Comoglio PM, Medico E, Pietrantonio F, Volante M, Pasini D, Chiarugi P, Giordano S, Corso S.

Cell Metab. 2018 Dec 4;28(6):848-865.e6. doi: 10.1016/j.cmet.2018.08.006. Epub 2018 Aug 30.

PMID:
30174307
6.

Nontypeable Haemophilus influenzae Lipooligosaccharide Expresses a Terminal Ketodeoxyoctanoate In Vivo, Which Can Be Used as a Target for Bactericidal Antibody.

Apicella MA, Coffin J, Ketterer M, Post DMB, Day CJ, Jen FE, Jennings MP.

MBio. 2018 Jul 31;9(4). pii: e01401-18. doi: 10.1128/mBio.01401-18.

7.

miR-205 mediates adaptive resistance to MET inhibition via ERRFI1 targeting and raised EGFR signaling.

Migliore C, Morando E, Ghiso E, Anastasi S, Leoni VP, Apicella M, Cora' D, Sapino A, Pietrantonio F, De Braud F, Columbano A, Segatto O, Giordano S.

EMBO Mol Med. 2018 Sep;10(9). pii: e8746. doi: 10.15252/emmm.201708746.

8.

Characterization of a nontypeable Haemophilus influenzae thermonuclease.

Cho C, Chande AT, Gakhar L, Hunt J, Ketterer MR, Apicella MA.

PLoS One. 2018 May 10;13(5):e0197010. doi: 10.1371/journal.pone.0197010. eCollection 2018.

9.

Perturbing the acetylation status of the Type IV pilus retraction motor, PilT, reduces Neisseria gonorrhoeae viability.

Hockenberry AM, Post DMB, Rhodes KA, Apicella M, So M.

Mol Microbiol. 2018 Dec;110(5):677-688. doi: 10.1111/mmi.13979. Epub 2018 Oct 28.

PMID:
29719082
10.

Rituximab Treatment Prevents Lymphoma Onset in Gastric Cancer Patient-Derived Xenografts.

Corso S, Cargnelutti M, Durando S, Menegon S, Apicella M, Migliore C, Capeloa T, Ughetto S, Isella C, Medico E, Bertotti A, Sassi F, Sarotto I, Casorzo L, Pisacane A, Mangioni M, Sottile A, Degiuli M, Fumagalli U, Sgroi G, Molfino S, De Manzoni G, Rosati R, De Simone M, Marrelli D, Saragoni L, Rausei S, Pallabazzer G, Roviello F, Cassoni P, Sapino A, Bass A, Giordano S.

Neoplasia. 2018 May;20(5):443-455. doi: 10.1016/j.neo.2018.02.003. Epub 2018 Mar 23.

11.

Healthy lifestyle promotion in primary schools through the board game Kaledo: a pilot cluster randomized trial.

Viggiano E, Viggiano A, Di Costanzo A, Viggiano A, Viggiano A, Andreozzi E, Romano V, Vicidomini C, Di Tuoro D, Gargano G, Incarnato L, Fevola C, Volta P, Tolomeo C, Scianni G, Santangelo C, Apicella M, Battista R, Raia M, Valentino I, Palumbo M, Messina G, Messina A, Monda M, De Luca B, Amaro S.

Eur J Pediatr. 2018 Sep;177(9):1371-1375. doi: 10.1007/s00431-018-3091-4. Epub 2018 Jan 20.

PMID:
29353440
12.

Chronic exposure to high doses of selenium in the first trimester of pregnancy: Case report and brief literature review.

D'Oria L, Apicella M, De Luca C, Licameli A, Neri C, Pellegrino M, Simeone D, De Santis M.

Birth Defects Res. 2018 Mar 1;110(4):372-375. doi: 10.1002/bdr2.1148. Epub 2018 Jan 19. Review.

PMID:
29350490
13.

Downregulating Neuropilin-2 Triggers a Novel Mechanism Enabling EGFR-Dependent Resistance to Oncogene-Targeted Therapies.

Rizzolio S, Battistini C, Cagnoni G, Apicella M, Vella V, Giordano S, Tamagnone L.

Cancer Res. 2018 Feb 15;78(4):1058-1068. doi: 10.1158/0008-5472.CAN-17-2020. Epub 2017 Dec 11.

14.

Characterization of Inner and Outer Membrane Proteins from Francisella tularensis Strains LVS and Schu S4 and Identification of Potential Subunit Vaccine Candidates.

Post DMB, Slütter B, Schilling B, Chande AT, Rasmussen JA, Jones BD, D'Souza AK, Reinders LM, Harty JT, Gibson BW, Apicella MA.

MBio. 2017 Oct 10;8(5). pii: e01592-17. doi: 10.1128/mBio.01592-17.

15.

Targeted therapies for gastric cancer: failures and hopes from clinical trials.

Apicella M, Corso S, Giordano S.

Oncotarget. 2017 Jan 26;8(34):57654-57669. doi: 10.18632/oncotarget.14825. eCollection 2017 Aug 22. Review.

16.

Identification and characterization of AckA-dependent protein acetylation in Neisseria gonorrhoeae.

Post DMB, Schilling B, Reinders LM, D'Souza AK, Ketterer MR, Kiel SJ, Chande AT, Apicella MA, Gibson BW.

PLoS One. 2017 Jun 27;12(6):e0179621. doi: 10.1371/journal.pone.0179621. eCollection 2017.

17.

Environmental cues and symbiont microbe-associated molecular patterns function in concert to drive the daily remodelling of the crypt-cell brush border of the Euprymna scolopes light organ.

Heath-Heckman EA, Foster J, Apicella MA, Goldman WE, McFall-Ngai M.

Cell Microbiol. 2016 Nov;18(11):1642-1652. doi: 10.1111/cmi.12602. Epub 2016 May 3.

18.

Four seasons for reflecting: Winter. Touch.

Piccoli GB, Giuva D, Ruff D, Genovese P, Apicella M, Kuprina N, Finnel S.

Nephrol Dial Transplant. 2016 Dec;31(12):2019-2022. Epub 2016 Sep 20. No abstract available.

PMID:
27651469
19.

Non-typeable Haemophilus influenzae protects human airway epithelial cells from a subsequent respiratory syncytial virus challenge.

Hartwig SM, Ketterer M, Apicella MA, Varga SM.

Virology. 2016 Nov;498:128-135. doi: 10.1016/j.virol.2016.08.020. Epub 2016 Aug 27.

20.

Dual MET/EGFR therapy leads to complete response and resistance prevention in a MET-amplified gastroesophageal xenopatient cohort.

Apicella M, Migliore C, Capelôa T, Menegon S, Cargnelutti M, Degiuli M, Sapino A, Sottile A, Sarotto I, Casorzo L, Cassoni P, De Simone M, Comoglio PM, Marsoni S, Corso S, Giordano S.

Oncogene. 2017 Mar 2;36(9):1200-1210. doi: 10.1038/onc.2016.283. Epub 2016 Aug 15.

PMID:
27524418
21.

Desialylation of Neisseria gonorrhoeae Lipooligosaccharide by Cervicovaginal Microbiome Sialidases: The Potential for Enhancing Infectivity in Men.

Ketterer MR, Rice PA, Gulati S, Kiel S, Byerly L, Fortenberry JD, Soper DE, Apicella MA.

J Infect Dis. 2016 Dec 1;214(11):1621-1628. Epub 2016 Jul 28.

22.

Evidence Suggesting That Francisella tularensis O-Antigen Capsule Contains a Lipid A-Like Molecule That Is Structurally Distinct from the More Abundant Free Lipid A.

Barker JH, Kaufman JW, Apicella MA, Weiss JP.

PLoS One. 2016 Jun 21;11(6):e0157842. doi: 10.1371/journal.pone.0157842. eCollection 2016.

23.

Seminal Plasma Promotes Neisseria gonorrhoeae Aggregation and Biofilm Formation.

Anderson MT, Byerly L, Apicella MA, Seifert HS.

J Bacteriol. 2016 Jul 28;198(16):2228-35. doi: 10.1128/JB.00165-16. Print 2016 Aug 15.

24.

Is gonococcal disease preventable? The importance of understanding immunity and pathogenesis in vaccine development.

Edwards JL, Jennings MP, Apicella MA, Seib KL.

Crit Rev Microbiol. 2016 Nov;42(6):928-41. doi: 10.3109/1040841X.2015.1105782. Epub 2016 Jan 23. Review.

25.

Comparative Analyses of the Lipooligosaccharides from Nontypeable Haemophilus influenzae and Haemophilus haemolyticus Show Differences in Sialic Acid and Phosphorylcholine Modifications.

Post DM, Ketterer MR, Coffin JE, Reinders LM, Munson RS Jr, Bair T, Murphy TF, Foster ED, Gibson BW, Apicella MA.

Infect Immun. 2016 Jan 4;84(3):765-74. doi: 10.1128/IAI.01185-15.

26.

Glycan:glycan interactions: High affinity biomolecular interactions that can mediate binding of pathogenic bacteria to host cells.

Day CJ, Tran EN, Semchenko EA, Tram G, Hartley-Tassell LE, Ng PS, King RM, Ulanovsky R, McAtamney S, Apicella MA, Tiralongo J, Morona R, Korolik V, Jennings MP.

Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):E7266-75. doi: 10.1073/pnas.1421082112. Epub 2015 Dec 16.

27.

Structural and functional features of a developmentally regulated lipopolysaccharide-binding protein.

Krasity BC, Troll JV, Lehnert EM, Hackett KT, Dillard JP, Apicella MA, Goldman WE, Weiss JP, McFall-Ngai MJ.

MBio. 2015 Oct 13;6(5):e01193-15. doi: 10.1128/mBio.01193-15.

28.

Dysregulation of the Transforming Growth Factor β Pathway in Induced Pluripotent Stem Cells Generated from Patients with Diamond Blackfan Anemia.

Ge J, Apicella M, Mills JA, Garçon L, French DL, Weiss MJ, Bessler M, Mason PJ.

PLoS One. 2015 Aug 10;10(8):e0134878. doi: 10.1371/journal.pone.0134878. eCollection 2015.

29.

The potential impact of vaccination on the prevalence of gonorrhea.

Craig AP, Gray RT, Edwards JL, Apicella MA, Jennings MP, Wilson DP, Seib KL.

Vaccine. 2015 Aug 26;33(36):4520-4525. doi: 10.1016/j.vaccine.2015.07.015. Epub 2015 Jul 17.

30.

Interactions of Francisella tularensis with Alveolar Type II Epithelial Cells and the Murine Respiratory Epithelium.

Faron M, Fletcher JR, Rasmussen JA, Apicella MA, Jones BD.

PLoS One. 2015 May 26;10(5):e0127458. doi: 10.1371/journal.pone.0127458. eCollection 2015.

31.

Impaired Telomere Maintenance and Decreased Canonical WNT Signaling but Normal Ribosome Biogenesis in Induced Pluripotent Stem Cells from X-Linked Dyskeratosis Congenita Patients.

Gu BW, Apicella M, Mills J, Fan JM, Reeves DA, French D, Podsakoff GM, Bessler M, Mason PJ.

PLoS One. 2015 May 18;10(5):e0127414. doi: 10.1371/journal.pone.0127414. eCollection 2015.

32.

A thermonuclease of Neisseria gonorrhoeae enhances bacterial escape from killing by neutrophil extracellular traps.

Juneau RA, Stevens JS, Apicella MA, Criss AK.

J Infect Dis. 2015 Jul 15;212(2):316-24. doi: 10.1093/infdis/jiv031. Epub 2015 Jan 20.

33.

Comparative analyses of proteins from Haemophilus influenzae biofilm and planktonic populations using metabolic labeling and mass spectrometry.

Post DM, Held JM, Ketterer MR, Phillips NJ, Sahu A, Apicella MA, Gibson BW.

BMC Microbiol. 2014 Dec 31;14:329. doi: 10.1186/s12866-014-0329-9.

34.

Role of the nuclease of nontypeable Haemophilus influenzae in dispersal of organisms from biofilms.

Cho C, Chande A, Gakhar L, Bakaletz LO, Jurcisek JA, Ketterer M, Shao J, Gotoh K, Foster E, Hunt J, O'Brien E, Apicella MA.

Infect Immun. 2015 Mar;83(3):950-7. doi: 10.1128/IAI.02601-14. Epub 2014 Dec 29.

35.

Platelet Activating Factor Receptor Activation Improves siRNA Uptake and RNAi Responses in Well-differentiated Airway Epithelia.

Krishnamurthy S, Behlke MA, Apicella MA, McCray PB Jr, Davidson BL.

Mol Ther Nucleic Acids. 2014 Jul 15;3:e175. doi: 10.1038/mtna.2014.26.

36.

Bacterial periplasmic sialic acid-binding proteins exhibit a conserved binding site.

Gangi Setty T, Cho C, Govindappa S, Apicella MA, Ramaswamy S.

Acta Crystallogr D Biol Crystallogr. 2014 Jul;70(Pt 7):1801-11. doi: 10.1107/S139900471400830X. Epub 2014 Jun 24.

37.

Lipid a is more than acyl chains.

Apicella MA.

Infect Immun. 2014 Jun;82(6):2160-1. doi: 10.1128/IAI.01830-14. Epub 2014 Apr 7.

38.

Quantification of confocal images of biofilms grown on irregular surfaces.

Sommerfeld Ross S, Tu MH, Falsetta ML, Ketterer MR, Kiedrowski MR, Horswill AR, Apicella MA, Reinhardt JM, Fiegel J.

J Microbiol Methods. 2014 May;100:111-20. doi: 10.1016/j.mimet.2014.02.020. Epub 2014 Mar 13.

39.

A model symbiosis reveals a role for sheathed-flagellum rotation in the release of immunogenic lipopolysaccharide.

Brennan CA, Hunt JR, Kremer N, Krasity BC, Apicella MA, McFall-Ngai MJ, Ruby EG.

Elife. 2014 Mar 4;3:e01579. doi: 10.7554/eLife.01579.

40.

Francisella tularensis Schu S4 lipopolysaccharide core sugar and O-antigen mutants are attenuated in a mouse model of tularemia.

Rasmussen JA, Post DM, Gibson BW, Lindemann SR, Apicella MA, Meyerholz DK, Jones BD.

Infect Immun. 2014 Apr;82(4):1523-39. doi: 10.1128/IAI.01640-13. Epub 2014 Jan 22.

41.

Hexa-acylated lipid A is required for host inflammatory response to Neisseria gonorrhoeae in experimental gonorrhea.

Zhou X, Gao X, Broglie PM, Kebaier C, Anderson JE, Thom N, Apicella MA, Sempowski GD, Duncan JA.

Infect Immun. 2014 Jan;82(1):184-92. doi: 10.1128/IAI.00890-13. Epub 2013 Oct 14.

42.

Site-specific acylation changes in the lipid A of Escherichia coli lpxL mutants grown at high temperatures.

Schilling B, Hunt J, Gibson BW, Apicella MA.

Innate Immun. 2014 Apr;20(3):269-82. doi: 10.1177/1753425913490534. Epub 2013 Jun 28.

43.

Ribosomal and hematopoietic defects in induced pluripotent stem cells derived from Diamond Blackfan anemia patients.

Garçon L, Ge J, Manjunath SH, Mills JA, Apicella M, Parikh S, Sullivan LM, Podsakoff GM, Gadue P, French DL, Mason PJ, Bessler M, Weiss MJ.

Blood. 2013 Aug 8;122(6):912-21. doi: 10.1182/blood-2013-01-478321. Epub 2013 Jun 6.

44.

Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer.

Bardelli A, Corso S, Bertotti A, Hobor S, Valtorta E, Siravegna G, Sartore-Bianchi A, Scala E, Cassingena A, Zecchin D, Apicella M, Migliardi G, Galimi F, Lauricella C, Zanon C, Perera T, Veronese S, Corti G, Amatu A, Gambacorta M, Diaz LA Jr, Sausen M, Velculescu VE, Comoglio P, Trusolino L, Di Nicolantonio F, Giordano S, Siena S.

Cancer Discov. 2013 Jun;3(6):658-73. doi: 10.1158/2159-8290.CD-12-0558. Epub 2013 Jun 2.

45.

Safety and immunological outcomes following human inoculation with nontypeable Haemophilus influenzae.

Winokur PL, Chaloner K, Doern GV, Ferreira J, Apicella MA.

J Infect Dis. 2013 Sep 1;208(5):728-38. doi: 10.1093/infdis/jit238. Epub 2013 May 28.

46.

Analysis of nontypeable haemophilus influenzae phase-variable genes during experimental human nasopharyngeal colonization.

Poole J, Foster E, Chaloner K, Hunt J, Jennings MP, Bair T, Knudtson K, Christensen E, Munson RS Jr, Winokur PL, Apicella MA.

J Infect Dis. 2013 Sep 1;208(5):720-7. doi: 10.1093/infdis/jit240. Epub 2013 May 28.

47.

Dual pili post-translational modifications synergize to mediate meningococcal adherence to platelet activating factor receptor on human airway cells.

Jen FE, Warren MJ, Schulz BL, Power PM, Swords WE, Weiser JN, Apicella MA, Edwards JL, Jennings MP.

PLoS Pathog. 2013;9(5):e1003377. doi: 10.1371/journal.ppat.1003377. Epub 2013 May 16.

48.

Characterization of an ntrX mutant of Neisseria gonorrhoeae reveals a response regulator that controls expression of respiratory enzymes in oxidase-positive proteobacteria.

Atack JM, Srikhanta YN, Djoko KY, Welch JP, Hasri NH, Steichen CT, Vanden Hoven RN, Grimmond SM, Othman DS, Kappler U, Apicella MA, Jennings MP, Edwards JL, McEwan AG.

J Bacteriol. 2013 Jun;195(11):2632-41. doi: 10.1128/JB.02062-12. Epub 2013 Apr 5.

49.

Bacterial bioluminescence regulates expression of a host cryptochrome gene in the squid-Vibrio symbiosis.

Heath-Heckman EA, Peyer SM, Whistler CA, Apicella MA, Goldman WE, McFall-Ngai MJ.

MBio. 2013 Apr 2;4(2). pii: e00167-13. doi: 10.1128/mBio.00167-13.

50.

Recombinant truncated AniA of pathogenic Neisseria elicits a non-native immune response and functional blocking antibodies.

Shewell LK, Ku SC, Schulz BL, Jen FE, Mubaiwa TD, Ketterer MR, Apicella MA, Jennings MP.

Biochem Biophys Res Commun. 2013 Feb 8;431(2):215-20. doi: 10.1016/j.bbrc.2012.12.132. Epub 2013 Jan 9.

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