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Items: 1 to 50 of 121

1.

The KdpFABC complex - K+ transport against all odds.

Pedersen BP, Stokes DL, Apell HJ.

Mol Membr Biol. 2019 Dec;35(1):21-38. doi: 10.1080/09687688.2019.1638977.

PMID:
31259644
2.

Subtle mutation, far-reaching effects.

Apell HJ.

J Gen Physiol. 2017 Nov 6;149(11):969-973. doi: 10.1085/jgp.201711899. Epub 2017 Oct 20. No abstract available.

3.

Modulation of the Na,K-ATPase by Magnesium Ions.

Apell HJ, Hitzler T, Schreiber G.

Biochemistry. 2017 Feb 21;56(7):1005-1016. doi: 10.1021/acs.biochem.6b01243. Epub 2017 Feb 9.

PMID:
28124894
4.

Electrostatic Stabilization Plays a Central Role in Autoinhibitory Regulation of the Na+,K+-ATPase.

Jiang Q, Garcia A, Han M, Cornelius F, Apell HJ, Khandelia H, Clarke RJ.

Biophys J. 2017 Jan 24;112(2):288-299. doi: 10.1016/j.bpj.2016.12.008.

5.

Assaying P-Type ATPases Reconstituted in Liposomes.

Apell HJ, Damnjanovic B.

Methods Mol Biol. 2016;1377:127-56. doi: 10.1007/978-1-4939-3179-8_14.

PMID:
26695029
6.

Molecular Mechanisms and Kinetic Effects of FXYD1 and Phosphomimetic Mutants on Purified Human Na,K-ATPase.

Mishra NK, Habeck M, Kirchner C, Haviv H, Peleg Y, Eisenstein M, Apell HJ, Karlish SJ.

J Biol Chem. 2015 Nov 27;290(48):28746-59. doi: 10.1074/jbc.M115.687913. Epub 2015 Oct 1.

7.

Probing the extracellular access channel of the Na,K-ATPase.

Grădinaru RV, Apell HJ.

Biochemistry. 2015 Apr 21;54(15):2508-19. doi: 10.1021/acs.biochem.5b00182. Epub 2015 Apr 9.

PMID:
25839323
8.

TtOmp85, a β-barrel assembly protein, functions by barrel augmentation.

Estrada Mallarino L, Fan E, Odermatt M, Müller M, Lin M, Liang J, Heinzelmann M, Fritsche F, Apell HJ, Welte W.

Biochemistry. 2015 Jan 27;54(3):844-52. doi: 10.1021/bi5011305. Epub 2015 Jan 8.

9.

KdpFABC reconstituted in Escherichia coli lipid vesicles: substrate dependence of the transport rate.

Damnjanovic B, Apell HJ.

Biochemistry. 2014 Sep 9;53(35):5674-82. doi: 10.1021/bi5008244. Epub 2014 Aug 28.

PMID:
25144826
10.

A novel tumor necrosis factor-mediated mechanism of direct epithelial sodium channel activation.

Czikora I, Alli A, Bao HF, Kaftan D, Sridhar S, Apell HJ, Gorshkov B, White R, Zimmermann A, Wendel A, Pauly-Evers M, Hamacher J, Garcia-Gabay I, Fischer B, Verin A, Bagi Z, Pittet JF, Shabbir W, Lemmens-Gruber R, Chakraborty T, Lazrak A, Matthay MA, Eaton DC, Lucas R.

Am J Respir Crit Care Med. 2014 Sep 1;190(5):522-32. doi: 10.1164/rccm.201405-0833OC.

11.

Does the sodium pump have secret levels?

Apell HJ.

Biophys J. 2014 Jun 17;106(12):2552-4. doi: 10.1016/j.bpj.2014.05.003. No abstract available.

12.

Role of protons in the pump cycle of KdpFABC investigated by time-resolved kinetic experiments.

Damnjanovic B, Apell HJ.

Biochemistry. 2014 May 20;53(19):3218-28. doi: 10.1021/bi500336w. Epub 2014 May 5.

PMID:
24766073
13.

Extracellular allosteric Na(+) binding to the Na(+),K(+)-ATPase in cardiac myocytes.

Garcia A, Fry NA, Karimi K, Liu CC, Apell HJ, Rasmussen HH, Clarke RJ.

Biophys J. 2013 Dec 17;105(12):2695-705. doi: 10.1016/j.bpj.2013.11.004.

14.

Surface charges of the membrane crucially affect regulation of Na,K-ATPase by phospholemman (FXYD1).

Cirri E, Kirchner C, Becker S, Katz A, Karlish SJ, Apell HJ.

J Membr Biol. 2013 Dec;246(12):967-79. doi: 10.1007/s00232-013-9600-5. Epub 2013 Oct 9.

PMID:
24105627
15.

Mechanistic analysis of the pump cycle of the KdpFABC P-type ATPase.

Damnjanovic B, Weber A, Potschies M, Greie JC, Apell HJ.

Biochemistry. 2013 Aug 20;52(33):5563-76. doi: 10.1021/bi400729e. Epub 2013 Aug 9.

PMID:
23930894
16.

Quantitative calculation of the role of the Na(+),K(+)-ATPase in thermogenesis.

Clarke RJ, Catauro M, Rasmussen HH, Apell HJ.

Biochim Biophys Acta. 2013 Oct;1827(10):1205-12. doi: 10.1016/j.bbabio.2013.06.010. Epub 2013 Jul 11.

17.

Kinetic comparisons of heart and kidney Na+,K(+)-ATPases.

Garcia A, Rasmussen HH, Apell HJ, Clarke RJ.

Biophys J. 2012 Aug 22;103(4):677-88. doi: 10.1016/j.bpj.2012.07.032. Erratum in: Biophys J. 2013 Mar 5;104(5):1214.

18.

Kinetics of luminal proton binding to the SR Ca-ATPase.

Fibich A, Apell HJ.

Biophys J. 2011 Oct 19;101(8):1896-904. doi: 10.1016/j.bpj.2011.09.014.

19.

Specific volume and compressibility of bilayer lipid membranes with incorporated Na,K-ATPase.

Hianik T, Rybár P, Krivánek R, Petríková M, Roudna M, Apell HJ.

Gen Physiol Biophys. 2011 Jun;30(2):145-53. doi: 10.4149/gpb_2011_02_145.

PMID:
21613669
20.

Phospholemman (FXYD1) raises the affinity of the human α1β1 isoform of Na,K-ATPase for Na ions.

Cirri E, Katz A, Mishra NK, Belogus T, Lifshitz Y, Garty H, Karlish SJ, Apell HJ.

Biochemistry. 2011 May 10;50(18):3736-48. doi: 10.1021/bi2001714. Epub 2011 Apr 15.

PMID:
21449573
21.

FXYD proteins stabilize Na,K-ATPase: amplification of specific phosphatidylserine-protein interactions.

Mishra NK, Peleg Y, Cirri E, Belogus T, Lifshitz Y, Voelker DR, Apell HJ, Garty H, Karlish SJ.

J Biol Chem. 2011 Mar 18;286(11):9699-712. doi: 10.1074/jbc.M110.184234. Epub 2011 Jan 12.

22.

Kinetics of K(+) occlusion by the phosphoenzyme of the Na(+),K(+)-ATPase.

Myers SL, Cornelius F, Apell HJ, Clarke RJ.

Biophys J. 2011 Jan 5;100(1):70-9. doi: 10.1016/j.bpj.2010.11.038.

23.

Proton diet for the sodium pump.

Apell HJ, Benz G, Sauerbrunn D.

Biochemistry. 2011 Jan 25;50(3):409-18. Epub 2010 Dec 27.

PMID:
21142048
24.

Inhibition of the gastric H,K-ATPase by clotrimazole.

Witzke A, Lindner K, Munson K, Apell HJ.

Biochemistry. 2010 Jun 1;49(21):4524-32. doi: 10.1021/bi1004014.

PMID:
20423050
25.

Interaction of ATP with the phosphoenzyme of the Na+,K+-ATPase.

Khalid M, Fouassier G, Apell HJ, Cornelius F, Clarke RJ.

Biochemistry. 2010 Feb 16;49(6):1248-58. doi: 10.1021/bi9019548.

PMID:
20063899
26.

Investigation of electrogenic partial reactions in detergent-solubilized Na,K-ATPase.

Habeck M, Cirri E, Katz A, Karlish SJ, Apell HJ.

Biochemistry. 2009 Sep 29;48(38):9147-55. doi: 10.1021/bi901148k.

PMID:
19708718
27.

ATP binding equilibria of the Na(+),K(+)-ATPase.

Pilotelle-Bunner A, Matthews JM, Cornelius F, Apell HJ, Sebban P, Clarke RJ.

Biochemistry. 2008 Dec 9;47(49):13103-14. doi: 10.1021/bi801593g.

PMID:
19006328
28.

Effect of clotrimazole on the pump cycle of the Na,K-ATPase.

Bartolommei G, Devaux N, Tadini-Buoninsegni F, Moncelli M, Apell HJ.

Biophys J. 2008 Aug;95(4):1813-25. doi: 10.1529/biophysj.108.133546. Epub 2008 May 9.

29.

Kinetics of proton binding to the sarcoplasmic reticulum Ca-ATPase in the E1 state.

Fibich A, Janko K, Apell HJ.

Biophys J. 2007 Nov 1;93(9):3092-104. Epub 2007 Jul 5.

30.

Allosteric effect of ATP on Na(+),K(+)-ATPase conformational kinetics.

Clarke RJ, Apell HJ, Kong BY.

Biochemistry. 2007 Jun 12;46(23):7034-44. Epub 2007 May 19.

PMID:
17511477
31.

Correct folding of the beta-barrel of the human membrane protein VDAC requires a lipid bilayer.

Shanmugavadivu B, Apell HJ, Meins T, Zeth K, Kleinschmidt JH.

J Mol Biol. 2007 Apr 20;368(1):66-78. Epub 2007 Feb 3.

PMID:
17336328
32.

Amphipathic polymers: tools to fold integral membrane proteins to their active form.

Pocanschi CL, Dahmane T, Gohon Y, Rappaport F, Apell HJ, Kleinschmidt JH, Popot JL.

Biochemistry. 2006 Nov 28;45(47):13954-61.

PMID:
17115690
33.

Palytoxin-induced effects on partial reactions of the Na,K-ATPase.

Harmel N, Apell HJ.

J Gen Physiol. 2006 Jul;128(1):103-18.

34.

Photochemical behavior and Na+,K+-ATPase sensitivity of voltage-sensitive styrylpyridinium fluorescent membrane probes.

Amoroso S, Agon VV, Starke-Peterkovic T, McLeod MD, Apell HJ, Sebban P, Clarke RJ.

Photochem Photobiol. 2006 Mar-Apr;82(2):495-502.

PMID:
16613504
35.

The major outer membrane protein of Fusobacterium nucleatum (FomA) folds and inserts into lipid bilayers via parallel folding pathways.

Pocanschi CL, Apell HJ, Puntervoll P, Høgh B, Jensen HB, Welte W, Kleinschmidt JH.

J Mol Biol. 2006 Jan 20;355(3):548-61. Epub 2005 Nov 9.

PMID:
16310217
36.

Effect of chaotropic anions on the sodium transport by the Na,K-ATPase.

Ayuyan AG, Sokolov VS, Lenz AA, Apell HJ.

Eur Biophys J. 2006 Feb;35(3):247-54. Epub 2005 Nov 16.

PMID:
16292645
37.

Mechanism of the Na,K-ATPase inhibition by MCS derivatives.

Stimac R, Kerek F, Apell HJ.

J Membr Biol. 2005 May;205(2):89-101.

PMID:
16283589
38.

Kinetics of Ca2+ binding to the SR Ca-ATPase in the E1 state.

Peinelt C, Apell HJ.

Biophys J. 2005 Oct;89(4):2427-33. Epub 2005 Jul 22.

39.

Electrogenic partial reactions of the gastric H,K-ATPase.

Diller A, Vagin O, Sachs G, Apell HJ.

Biophys J. 2005 May;88(5):3348-59. Epub 2005 Mar 4.

40.

Photodynamic inactivation of the Na,K-ATPase occurs via different pathways.

Killig F, Stark G, Apell HJ.

J Membr Biol. 2004 Aug 1;200(3):133-44.

PMID:
15625822
41.

How do P-type ATPases transport ions?

Apell HJ.

Bioelectrochemistry. 2004 Jun;63(1-2):149-56. Review.

PMID:
15110265
42.
43.

Structure-function relationship in P-type ATPases--a biophysical approach.

Apell HJ.

Rev Physiol Biochem Pharmacol. 2003;150:1-35. Epub 2003 Jun 17. Review.

PMID:
12811587
44.

Macrocyclic carbon suboxide oligomers as potent inhibitors of the Na,K-ATPase.

Stimac R, Kerek F, Apell HJ.

Ann N Y Acad Sci. 2003 Apr;986:327-9. No abstract available.

PMID:
12763840
45.

Time-resolved partial reactions of the SR Ca-ATPase investigated with a fluorescent styryl dye.

Peinelt C, Apell HJ.

Ann N Y Acad Sci. 2003 Apr;986:325-6. No abstract available.

PMID:
12763839
46.

Salt effects on the kinetics of the electrogenic Na+ transport in the Na,K-ATPase.

Ayuyan AG, Sokolov VS, Apell HJ.

Ann N Y Acad Sci. 2003 Apr;986:252-4. No abstract available.

PMID:
12763811
47.

Negative changes of the membrane capacitance due to electrogenic Na transport by the Na,K-ATPase.

Sokolov VS, Lenz AA, Apell HJ.

Ann N Y Acad Sci. 2003 Apr;986:229-31. No abstract available.

PMID:
12763802
48.

Kinetic investigations of the mechanism of the rate-determining step of the Na+,K+-ATPase pump cycle.

Clarke RJ, Humphrey PA, Lüpfert C, Apell HJ, Cornelius F.

Ann N Y Acad Sci. 2003 Apr;986:159-62.

PMID:
12763790
49.

Toward an understanding of ion transport through the Na,K-ATPase.

Apell HJ.

Ann N Y Acad Sci. 2003 Apr;986:133-40.

PMID:
12763786
50.

Characterization of the macrocyclic carbon suboxide factors as potent Na,K-ATPase and SR Ca-ATPase inhibitors.

Kerek F, Stimac R, Apell HJ, Freudenmann F, Moroder L.

Biochim Biophys Acta. 2002 Dec 23;1567(1-2):213-20.

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