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Items: 1 to 50 of 330

1.

A Multisensor System for the Characterization of the Field Pressure in Terrain. Accuracy, Response, and Adjustments.

Sicilia I, Aparicio S, Frutos B, Muñoz E, González M, Anaya JJ.

Sensors (Basel). 2019 Sep 12;19(18). pii: E3942. doi: 10.3390/s19183942.

2.

Probabilistic cell-type assignment of single-cell RNA-seq for tumor microenvironment profiling.

Zhang AW, O'Flanagan C, Chavez EA, Lim JLP, Ceglia N, McPherson A, Wiens M, Walters P, Chan T, Hewitson B, Lai D, Mottok A, Sarkozy C, Chong L, Aoki T, Wang X, Weng AP, McAlpine JN, Aparicio S, Steidl C, Campbell KR, Shah SP.

Nat Methods. 2019 Oct;16(10):1007-1015. doi: 10.1038/s41592-019-0529-1. Epub 2019 Sep 9.

PMID:
31501550
3.

Quantum Chemistry Insight into the Interactions Between Deep Eutectic Solvents and SO2.

Atilhan M, Altamash T, Aparicio S.

Molecules. 2019 Aug 15;24(16). pii: E2963. doi: 10.3390/molecules24162963.

4.

Effect of ambient temperature variations on an indigenous microalgae-nitrifying bacteria culture dominated by Chlorella.

González-Camejo J, Aparicio S, Ruano MV, Borrás L, Barat R, Ferrer J.

Bioresour Technol. 2019 Oct;290:121788. doi: 10.1016/j.biortech.2019.121788. Epub 2019 Jul 11.

PMID:
31326649
5.

Design of arginine-based therapeutic deep eutectic solvents as drug solubilization vehicles for active pharmaceutical ingredients.

Gutiérrez A, Aparicio S, Atilhan M.

Phys Chem Chem Phys. 2019 May 28;21(20):10621-10634. doi: 10.1039/c9cp01408j. Epub 2019 May 13.

PMID:
31080981
6.

Pharmacological systems analysis defines EIF4A3 functions in cell-cycle and RNA stress granule formation.

Mazloomian A, Araki S, Ohori M, El-Naggar AM, Yap D, Bashashati A, Nakao S, Sorensen PH, Nakanishi A, Shah S, Aparicio S.

Commun Biol. 2019 May 3;2:165. doi: 10.1038/s42003-019-0391-9. eCollection 2019.

7.

Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups.

Rueda OM, Sammut SJ, Seoane JA, Chin SF, Caswell-Jin JL, Callari M, Batra R, Pereira B, Bruna A, Ali HR, Provenzano E, Liu B, Parisien M, Gillett C, McKinney S, Green AR, Murphy L, Purushotham A, Ellis IO, Pharoah PD, Rueda C, Aparicio S, Caldas C, Curtis C.

Nature. 2019 Mar;567(7748):399-404. doi: 10.1038/s41586-019-1007-8. Epub 2019 Mar 13.

8.

clonealign: statistical integration of independent single-cell RNA and DNA sequencing data from human cancers.

Campbell KR, Steif A, Laks E, Zahn H, Lai D, McPherson A, Farahani H, Kabeer F, O'Flanagan C, Biele J, Brimhall J, Wang B, Walters P, Consortium I, Bouchard-Côté A, Aparicio S, Shah SP.

Genome Biol. 2019 Mar 12;20(1):54. doi: 10.1186/s13059-019-1645-z.

9.

Resource recovery from sulphate-rich sewage through an innovative anaerobic-based water resource recovery facility (WRRF).

Seco A, Aparicio S, González-Camejo J, Jiménez-Benítez A, Mateo O, Mora JF, Noriega-Hevia G, Sanchis-Perucho P, Serna-García R, Zamorano-López N, Giménez JB, Ruiz-Martínez A, Aguado D, Barat R, Borrás L, Bouzas A, Martí N, Pachés M, Ribes J, Robles A, Ruano MV, Serralta J, Ferrer J.

Water Sci Technol. 2018 Dec;78(9):1925-1936. doi: 10.2166/wst.2018.492.

PMID:
30566096
10.

A theoretical study on lidocaine solubility in deep eutectic solvents.

Gutiérrez A, Atilhan M, Aparicio S.

Phys Chem Chem Phys. 2018 Nov 7;20(43):27464-27473. doi: 10.1039/c8cp05641b.

PMID:
30357182
11.

Theoretical Study on Molten Alkali Carbonate Interfaces.

Gutiérrez A, Garroni S, Souentie S, Cuesta-López S, Yakoumis I, Aparicio S.

Langmuir. 2018 Oct 30;34(43):13065-13076. doi: 10.1021/acs.langmuir.8b02907. Epub 2018 Oct 22.

PMID:
30296102
12.

Decoding Transcriptome Dynamics of Genome-Encoded Polyadenylation and Autoregulation with Small-Molecule Modulators of Alternative Polyadenylation.

Araki S, Nakayama Y, Sano O, Nakao S, Shimizu-Ogasawara M, Toyoshiba H, Nakanishi A, Aparicio S.

Cell Chem Biol. 2018 Dec 20;25(12):1470-1484.e5. doi: 10.1016/j.chembiol.2018.09.006. Epub 2018 Oct 4.

PMID:
30293940
13.

Epigenetic Study in Parkinson's Disease: A Pilot Analysis of DNA Methylation in Candidate Genes in Brain.

Navarro-Sánchez L, Águeda-Gómez B, Aparicio S, Pérez-Tur J.

Cells. 2018 Sep 26;7(10). pii: E150. doi: 10.3390/cells7100150.

14.

High-Resolution Single-Cell DNA Methylation Measurements Reveal Epigenetically Distinct Hematopoietic Stem Cell Subpopulations.

Hui T, Cao Q, Wegrzyn-Woltosz J, O'Neill K, Hammond CA, Knapp DJHF, Laks E, Moksa M, Aparicio S, Eaves CJ, Karsan A, Hirst M.

Stem Cell Reports. 2018 Aug 14;11(2):578-592. doi: 10.1016/j.stemcr.2018.07.003. Epub 2018 Aug 2.

15.

Discovery of 3-Benzyl-1-( trans-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors.

Ito M, Tanaka T, Toita A, Uchiyama N, Kokubo H, Morishita N, Klein MG, Zou H, Murakami M, Kondo M, Sameshima T, Araki S, Endo S, Kawamoto T, Morin GB, Aparicio SA, Nakanishi A, Maezaki H, Imaeda Y.

J Med Chem. 2018 Sep 13;61(17):7710-7728. doi: 10.1021/acs.jmedchem.8b00683. Epub 2018 Aug 20.

PMID:
30067358
16.

Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer.

Zhang AW, McPherson A, Milne K, Kroeger DR, Hamilton PT, Miranda A, Funnell T, Little N, de Souza CPE, Laan S, LeDoux S, Cochrane DR, Lim JLP, Yang W, Roth A, Smith MA, Ho J, Tse K, Zeng T, Shlafman I, Mayo MR, Moore R, Failmezger H, Heindl A, Wang YK, Bashashati A, Grewal DS, Brown SD, Lai D, Wan ANC, Nielsen CB, Huebner C, Tessier-Cloutier B, Anglesio MS, Bouchard-Côté A, Yuan Y, Wasserman WW, Gilks CB, Karnezis AN, Aparicio S, McAlpine JN, Huntsman DG, Holt RA, Nelson BH, Shah SP.

Cell. 2018 Jun 14;173(7):1755-1769.e22. doi: 10.1016/j.cell.2018.03.073. Epub 2018 May 10.

17.

Homologous recombination deficiency and host anti-tumor immunity in triple-negative breast cancer.

Telli ML, Stover DG, Loi S, Aparicio S, Carey LA, Domchek SM, Newman L, Sledge GW, Winer EP.

Breast Cancer Res Treat. 2018 Aug;171(1):21-31. doi: 10.1007/s10549-018-4807-x. Epub 2018 May 7. Review.

PMID:
29736741
18.

A theoretical study on mixtures of amino acid-based ionic liquids.

Herrera C, Atilhan M, Aparicio S.

Phys Chem Chem Phys. 2018 Apr 18;20(15):10213-10223. doi: 10.1039/c7cp08533h.

PMID:
29594303
19.

Nutritional patterns associated with the maintenance of neurocognitive functions and the risk of dementia and Alzheimer's disease: A focus on human studies.

Pistollato F, Iglesias RC, Ruiz R, Aparicio S, Crespo J, Lopez LD, Manna PP, Giampieri F, Battino M.

Pharmacol Res. 2018 May;131:32-43. doi: 10.1016/j.phrs.2018.03.012. Epub 2018 Mar 16. Review.

PMID:
29555333
20.

Associations between genomic stratification of breast cancer and centrally reviewed tumour pathology in the METABRIC cohort.

Mukherjee A, Russell R, Chin SF, Liu B, Rueda OM, Ali HR, Turashvili G, Mahler-Araujo B, Ellis IO, Aparicio S, Caldas C, Provenzano E.

NPJ Breast Cancer. 2018 Mar 7;4:5. doi: 10.1038/s41523-018-0056-8. eCollection 2018.

21.

Molecular Modeling Analysis of CO2 Absorption by Glymes.

Gutiérrez A, Atilhan M, Aparicio S.

J Phys Chem B. 2018 Feb 15;122(6):1948-1957. doi: 10.1021/acs.jpcb.7b10276. Epub 2018 Feb 6.

PMID:
29377697
22.

Are by-products from beeswax recycling process a new promising source of bioactive compounds with biomedical properties?

Giampieri F, Quiles JL, Orantes-Bermejo FJ, Gasparrini M, Forbes-Hernandez TY, Sánchez-González C, Llopis J, Rivas-García L, Afrin S, Varela-López A, Cianciosi D, Reboredo-Rodriguez P, Fernández-Piñar CT, Iglesias RC, Ruiz R, Aparicio S, Crespo J, Dzul Lopez L, Xiao J, Battino M.

Food Chem Toxicol. 2018 Feb;112:126-133. doi: 10.1016/j.fct.2017.12.041. Epub 2017 Dec 25.

PMID:
29284135
23.

Wannier-Mott Excitons in Nanoscale Molecular Ices.

Chen YJ, Muñoz Caro GM, Aparicio S, Jiménez-Escobar A, Lasne J, Rosu-Finsen A, McCoustra MRS, Cassidy AM, Field D.

Phys Rev Lett. 2017 Oct 13;119(15):157703. doi: 10.1103/PhysRevLett.119.157703. Epub 2017 Oct 13.

PMID:
29077429
24.

Engineered in-vitro cell line mixtures and robust evaluation of computational methods for clonal decomposition and longitudinal dynamics in cancer.

Farahani H, de Souza CPE, Billings R, Yap D, Shumansky K, Wan A, Lai D, Mes-Masson AM, Aparicio S, P Shah S.

Sci Rep. 2017 Oct 18;7(1):13467. doi: 10.1038/s41598-017-13338-8.

25.

The use of natural compounds for the targeting and chemoprevention of ovarian cancer.

Pistollato F, Calderón Iglesias R, Ruiz R, Aparicio S, Crespo J, Dzul Lopez L, Giampieri F, Battino M.

Cancer Lett. 2017 Dec 28;411:191-200. doi: 10.1016/j.canlet.2017.09.050. Epub 2017 Oct 7.

PMID:
29017913
26.

Correction to: ReMixT: clone-specific genomic structure estimation in cancer.

McPherson AW, Roth A, Ha G, Chauve C, Steif A, de Souza CPE, Eirew P, Bouchard-Côté A, Aparicio S, Sahinalp SC, Shah SP.

Genome Biol. 2017 Oct 6;18(1):188. doi: 10.1186/s13059-017-1327-7. No abstract available.

27.

Chronic Silymarin, Quercetin and Naringenin Treatments Increase Monoamines Synthesis and Hippocampal Sirt1 Levels Improving Cognition in Aged Rats.

Sarubbo F, Ramis MR, Kienzer C, Aparicio S, Esteban S, Miralles A, Moranta D.

J Neuroimmune Pharmacol. 2018 Mar;13(1):24-38. doi: 10.1007/s11481-017-9759-0. Epub 2017 Aug 14.

PMID:
28808887
28.

ReMixT: clone-specific genomic structure estimation in cancer.

McPherson AW, Roth A, Ha G, Chauve C, Steif A, de Souza CPE, Eirew P, Bouchard-Côté A, Aparicio S, Sahinalp SC, Shah SP.

Genome Biol. 2017 Jul 27;18(1):140. doi: 10.1186/s13059-017-1267-2. Erratum in: Genome Biol. 2017 Oct 6;18(1):188.

29.

Insights into Glycol Ether-Alkanol Mixtures from a Combined Experimental and Theoretical Approach.

Alcalde R, Gutiérrez A, Atilhan M, Trenzado JL, Aparicio S.

J Phys Chem B. 2017 Jun 8;121(22):5601-5612. doi: 10.1021/acs.jpcb.7b03598. Epub 2017 May 26.

PMID:
28520432
30.

Elucidating the Properties of Graphene-Deep Eutectic Solvents Interface.

Atilhan M, Costa LT, Aparicio S.

Langmuir. 2017 May 30;33(21):5154-5165. doi: 10.1021/acs.langmuir.7b00767. Epub 2017 May 16.

PMID:
28485942
31.

Impact of serum HER2, TIMP-1, and CAIX on outcome for HER2+ metastatic breast cancer patients: CCTG MA.31 (lapatinib vs. trastuzumab).

Ho D, Huang J, Chapman JW, Leitzel K, Ali SM, Shepherd L, Parulekar WR, Ellis CE, Crescnzo RJ, Zhu L, Virk S, Nomikos D, Aparicio S, Gelmon KA, Carney WP, Lipton A.

Breast Cancer Res Treat. 2017 Aug;164(3):571-580. doi: 10.1007/s10549-017-4273-x. Epub 2017 May 8.

PMID:
28484925
32.

Discovery and Characterization of a Eukaryotic Initiation Factor 4A-3-Selective Inhibitor That Suppresses Nonsense-Mediated mRNA Decay.

Iwatani-Yoshihara M, Ito M, Ishibashi Y, Oki H, Tanaka T, Morishita D, Ito T, Kimura H, Imaeda Y, Aparicio S, Nakanishi A, Kawamoto T.

ACS Chem Biol. 2017 Jul 21;12(7):1760-1768. doi: 10.1021/acschembio.7b00041. Epub 2017 May 10.

PMID:
28440616
33.

Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes.

Wang YK, Bashashati A, Anglesio MS, Cochrane DR, Grewal DS, Ha G, McPherson A, Horlings HM, Senz J, Prentice LM, Karnezis AN, Lai D, Aniba MR, Zhang AW, Shumansky K, Siu C, Wan A, McConechy MK, Li-Chang H, Tone A, Provencher D, de Ladurantaye M, Fleury H, Okamoto A, Yanagida S, Yanaihara N, Saito M, Mungall AJ, Moore R, Marra MA, Gilks CB, Mes-Masson AM, McAlpine JN, Aparicio S, Huntsman DG, Shah SP.

Nat Genet. 2017 Jun;49(6):856-865. doi: 10.1038/ng.3849. Epub 2017 Apr 24.

PMID:
28436987
34.

Discovery of Novel 1,4-Diacylpiperazines as Selective and Cell-Active eIF4A3 Inhibitors.

Ito M, Tanaka T, Cary DR, Iwatani-Yoshihara M, Kamada Y, Kawamoto T, Aparicio S, Nakanishi A, Imaeda Y.

J Med Chem. 2017 Apr 27;60(8):3335-3351. doi: 10.1021/acs.jmedchem.6b01904. Epub 2017 Apr 11.

PMID:
28358513
35.

CDK12 regulates alternative last exon mRNA splicing and promotes breast cancer cell invasion.

Tien JF, Mazloomian A, Cheng SG, Hughes CS, Chow CCT, Canapi LT, Oloumi A, Trigo-Gonzalez G, Bashashati A, Xu J, Chang VC, Shah SP, Aparicio S, Morin GB.

Nucleic Acids Res. 2017 Jun 20;45(11):6698-6716. doi: 10.1093/nar/gkx187.

36.

Atrophin controls developmental signaling pathways via interactions with Trithorax-like.

Yeung K, Boija A, Karlsson E, Holmqvist PH, Tsatskis Y, Nisoli I, Yap D, Lorzadeh A, Moksa M, Hirst M, Aparicio S, Fanto M, Stenberg P, Mannervik M, McNeill H.

Elife. 2017 Mar 22;6. pii: e23084. doi: 10.7554/eLife.23084.

37.

Local environment structure and dynamics of CO2 in the 1-ethyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide and related ionic liquids.

Lourenço TC, Aparicio S, Costa GC, Costa LT.

J Chem Phys. 2017 Mar 14;146(10):104502. doi: 10.1063/1.4977786.

PMID:
28298100
38.

Discovery of selective ATP-competitive eIF4A3 inhibitors.

Ito M, Iwatani M, Kamada Y, Sogabe S, Nakao S, Tanaka T, Kawamoto T, Aparicio S, Nakanishi A, Imaeda Y.

Bioorg Med Chem. 2017 Apr 1;25(7):2200-2209. doi: 10.1016/j.bmc.2017.02.035. Epub 2017 Feb 20.

PMID:
28283335
39.

ddClone: joint statistical inference of clonal populations from single cell and bulk tumour sequencing data.

Salehi S, Steif A, Roth A, Aparicio S, Bouchard-Côté A, Shah SP.

Genome Biol. 2017 Mar 1;18(1):44. doi: 10.1186/s13059-017-1169-3.

40.

CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor.

Funnell T, Tasaki S, Oloumi A, Araki S, Kong E, Yap D, Nakayama Y, Hughes CS, Cheng SG, Tozaki H, Iwatani M, Sasaki S, Ohashi T, Miyazaki T, Morishita N, Morishita D, Ogasawara-Shimizu M, Ohori M, Nakao S, Karashima M, Sano M, Murai A, Nomura T, Uchiyama N, Kawamoto T, Hara R, Nakanishi O, Shumansky K, Rosner J, Wan A, McKinney S, Morin GB, Nakanishi A, Shah S, Toyoshiba H, Aparicio S.

Nat Commun. 2017 Feb 23;8(1):7. doi: 10.1038/s41467-016-0008-7.

41.

CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.

Xu H, Di Antonio M, McKinney S, Mathew V, Ho B, O'Neil NJ, Santos ND, Silvester J, Wei V, Garcia J, Kabeer F, Lai D, Soriano P, Banáth J, Chiu DS, Yap D, Le DD, Ye FB, Zhang A, Thu K, Soong J, Lin SC, Tsai AH, Osako T, Algara T, Saunders DN, Wong J, Xian J, Bally MB, Brenton JD, Brown GW, Shah SP, Cescon D, Mak TW, Caldas C, Stirling PC, Hieter P, Balasubramanian S, Aparicio S.

Nat Commun. 2017 Feb 17;8:14432. doi: 10.1038/ncomms14432.

42.

Erratum to: Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer.

Hu Z, Mao JH, Curtis C, Huang G, Gu S, Heiser L, Lenburg ME, Korkola JE, Bayani N, Samarajiwa S, Seoane JA, Dane MA, Esch A, Feiler HS, Wang NJ, Hardwicke MA, Laquerre S, Jackson J, Wood KW, Weber B, Spellman PT, Aparicio S, Wooster R, Caldas C, Gray JW.

Breast Cancer Res. 2017 Feb 9;19(1):17. doi: 10.1186/s13058-017-0809-6. No abstract available.

43.

Simultaneous CO2 and SO2 capture by using ionic liquids: a theoretical approach.

García G, Atilhan M, Aparicio S.

Phys Chem Chem Phys. 2017 Feb 15;19(7):5411-5422. doi: 10.1039/c6cp08151g.

PMID:
28164188
44.

Scalable whole-genome single-cell library preparation without preamplification.

Zahn H, Steif A, Laks E, Eirew P, VanInsberghe M, Shah SP, Aparicio S, Hansen CL.

Nat Methods. 2017 Feb;14(2):167-173. doi: 10.1038/nmeth.4140. Epub 2017 Jan 9.

PMID:
28068316
45.

Patient-derived xenograft (PDX) models in basic and translational breast cancer research.

Dobrolecki LE, Airhart SD, Alferez DG, Aparicio S, Behbod F, Bentires-Alj M, Brisken C, Bult CJ, Cai S, Clarke RB, Dowst H, Ellis MJ, Gonzalez-Suarez E, Iggo RD, Kabos P, Li S, Lindeman GJ, Marangoni E, McCoy A, Meric-Bernstam F, Piwnica-Worms H, Poupon MF, Reis-Filho J, Sartorius CA, Scabia V, Sflomos G, Tu Y, Vaillant F, Visvader JE, Welm A, Wicha MS, Lewis MT.

Cancer Metastasis Rev. 2016 Dec;35(4):547-573. doi: 10.1007/s10555-016-9653-x. Review.

46.

The RNA helicase DDX39B and its paralog DDX39A regulate androgen receptor splice variant AR-V7 generation.

Nakata D, Nakao S, Nakayama K, Araki S, Nakayama Y, Aparicio S, Hara T, Nakanishi A.

Biochem Biophys Res Commun. 2017 Jan 29;483(1):271-276. doi: 10.1016/j.bbrc.2016.12.153. Epub 2016 Dec 23.

PMID:
28025139
47.

Behavior of Deep Eutectic Solvents under External Electric Fields: A Molecular Dynamics Approach.

Atilhan M, Aparicio S.

J Phys Chem B. 2017 Jan 12;121(1):221-232. doi: 10.1021/acs.jpcb.6b09714. Epub 2016 Dec 22.

PMID:
27936795
48.

Analysis of Normal Human Mammary Epigenomes Reveals Cell-Specific Active Enhancer States and Associated Transcription Factor Networks.

Pellacani D, Bilenky M, Kannan N, Heravi-Moussavi A, Knapp DJHF, Gakkhar S, Moksa M, Carles A, Moore R, Mungall AJ, Marra MA, Jones SJM, Aparicio S, Hirst M, Eaves CJ.

Cell Rep. 2016 Nov 15;17(8):2060-2074. doi: 10.1016/j.celrep.2016.10.058.

49.

Routing Topologies of Wireless Sensor Networks for Health Monitoring of a Cultural Heritage Site.

Aparicio S, Martínez-Garrido MI, Ranz J, Fort R, Izquierdo MÁ.

Sensors (Basel). 2016 Oct 19;16(10). pii: E1732.

50.

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.

Bruna A, Rueda OM, Greenwood W, Batra AS, Callari M, Batra RN, Pogrebniak K, Sandoval J, Cassidy JW, Tufegdzic-Vidakovic A, Sammut SJ, Jones L, Provenzano E, Baird R, Eirew P, Hadfield J, Eldridge M, McLaren-Douglas A, Barthorpe A, Lightfoot H, O'Connor MJ, Gray J, Cortes J, Baselga J, Marangoni E, Welm AL, Aparicio S, Serra V, Garnett MJ, Caldas C.

Cell. 2016 Sep 22;167(1):260-274.e22. doi: 10.1016/j.cell.2016.08.041. Epub 2016 Sep 15.

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