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Items: 1 to 50 of 573

1.

Endoscopic detection and differentiation of esophageal lesions using a deep neural network.

Ohmori M, Ishihara R, Aoyama K, Nakagawa K, Iwagami H, Matsuura N, Shichijo S, Yamamoto K, Nagaike K, Nakahara M, Inoue T, Aoi K, Okada H, Tada T.

Gastrointest Endosc. 2019 Oct 1. pii: S0016-5107(19)32301-6. doi: 10.1016/j.gie.2019.09.034. [Epub ahead of print]

PMID:
31585124
2.

Convolutional Neural Network for Differentiating Gastric Cancer from Gastritis Using Magnified Endoscopy with Narrow Band Imaging.

Horiuchi Y, Aoyama K, Tokai Y, Hirasawa T, Yoshimizu S, Ishiyama A, Yoshio T, Tsuchida T, Fujisaki J, Tada T.

Dig Dis Sci. 2019 Oct 4. doi: 10.1007/s10620-019-05862-6. [Epub ahead of print]

PMID:
31584138
3.

Odf2 haploinsufficiency causes a new type of decapitated and decaudated spermatozoa, Odf2-DDS, in mice.

Ito C, Akutsu H, Yao R, Yoshida K, Yamatoya K, Mutoh T, Makino T, Aoyama K, Ishikawa H, Kunimoto K, Tsukita S, Noda T, Kikkawa M, Toshimori K.

Sci Rep. 2019 Oct 3;9(1):14249. doi: 10.1038/s41598-019-50516-2.

4.

KDM2B in polycomb repressive complex 1.1 functions as a tumor suppressor in the initiation of T-cell leukemogenesis.

Isshiki Y, Nakajima-Takagi Y, Oshima M, Aoyama K, Rizk M, Kurosawa S, Saraya A, Kondo T, Sakaida E, Nakaseko C, Yokote K, Koseki H, Iwama A.

Blood Adv. 2019 Sep 10;3(17):2537-2549. doi: 10.1182/bloodadvances.2018028522.

5.

Artificial plateau construction during the Preclassic period at the Maya site of Ceibal, Guatemala.

Inomata T, Triadan D, Pinzón F, Aoyama K.

PLoS One. 2019 Aug 30;14(8):e0221943. doi: 10.1371/journal.pone.0221943. eCollection 2019.

6.

Clinical usefulness of a deep learning-based system as the first screening on small-bowel capsule endoscopy reading.

Aoki T, Yamada A, Aoyama K, Saito H, Fujisawa G, Odawara N, Kondo R, Tsuboi A, Ishibashi R, Nakada A, Niikura R, Fujishiro M, Oka S, Ishihara S, Matsuda T, Nakahori M, Tanaka S, Koike K, Tada T.

Dig Endosc. 2019 Aug 23. doi: 10.1111/den.13517. [Epub ahead of print]

PMID:
31441972
7.

Association of Maternal Age With Severe Maternal Morbidity and Mortality in Canada.

Aoyama K, Pinto R, Ray JG, Hill AD, Scales DC, Lapinsky SE, Hladunewich MA, Seaward GR, Fowler RA.

JAMA Netw Open. 2019 Aug 2;2(8):e199875. doi: 10.1001/jamanetworkopen.2019.9875.

8.

Parkinson's disease is a type of amyloidosis featuring accumulation of amyloid fibrils of α-synuclein.

Araki K, Yagi N, Aoyama K, Choong CJ, Hayakawa H, Fujimura H, Nagai Y, Goto Y, Mochizuki H.

Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17963-17969. doi: 10.1073/pnas.1906124116. Epub 2019 Aug 19.

9.

Bmi1 restricts the adipogenic differentiation of bone marrow stromal cells to maintain the integrity of the hematopoietic stem cell niche.

Kato Y, Hou LB, Miyagi S, Nitta E, Aoyama K, Shinoda D, Yamazaki S, Kuribayashi W, Isshiki Y, Koide S, Si S, Saraya A, Matsuzaki Y, van Lohuizen M, Iwama A.

Exp Hematol. 2019 Aug;76:24-37. doi: 10.1016/j.exphem.2019.07.006. Epub 2019 Aug 11.

PMID:
31408689
10.

Artificial intelligence using a convolutional neural network for automatic detection of small-bowel angioectasia in capsule endoscopy images.

Tsuboi A, Oka S, Aoyama K, Saito H, Aoki T, Yamada A, Matsuda T, Fujishiro M, Ishihara S, Nakahori M, Koike K, Tanaka S, Tada T.

Dig Endosc. 2019 Aug 7. doi: 10.1111/den.13507. [Epub ahead of print]

PMID:
31392767
11.

Congenital goitrous hypothyroidism is caused by dysfunction of the iodide transporter SLC26A7.

Ishii J, Suzuki A, Kimura T, Tateyama M, Tanaka T, Yazawa T, Arimasu Y, Chen IS, Aoyama K, Kubo Y, Saitoh S, Mizuno H, Kamma H.

Commun Biol. 2019 Jul 24;2:270. doi: 10.1038/s42003-019-0503-6. eCollection 2019.

12.

Assessment of Therapeutic Interventions and Lung Protective Ventilation in Patients With Moderate to Severe Acute Respiratory Distress Syndrome: A Systematic Review and Network Meta-analysis.

Aoyama H, Uchida K, Aoyama K, Pechlivanoglou P, Englesakis M, Yamada Y, Fan E.

JAMA Netw Open. 2019 Jul 3;2(7):e198116. doi: 10.1001/jamanetworkopen.2019.8116.

13.

New PCNT candidate missense variant in a patient with oral and maxillofacial osteodysplasia: a case report.

Aoyama KI, Kimura M, Yamazaki H, Uchibori M, Kojima R, Osawa Y, Hosomichi K, Ota Y, Tanaka M, Yamada S, Nishimura G.

BMC Med Genet. 2019 Jul 16;20(1):126. doi: 10.1186/s12881-019-0858-z.

14.

Direct Writing of Copper Micropatterns Using Near-Infrared Femtosecond Laser-Pulse-Induced Reduction of Glyoxylic Acid Copper Complex.

Mizoshiri M, Aoyama K, Uetsuki A, Ohishi T.

Micromachines (Basel). 2019 Jun 17;10(6). pii: E401. doi: 10.3390/mi10060401.

15.

Transition from Leigh syndrome to MELAS syndrome in a patient with heteroplasmic MT-ND3 m.10158T>C.

Kori A, Hori I, Tanaka T, Aoyama K, Ito K, Hattori A, Ban K, Okazaki Y, Murayama K, Saitoh S.

Brain Dev. 2019 Oct;41(9):803-807. doi: 10.1016/j.braindev.2019.05.006. Epub 2019 Jun 6.

PMID:
31178082
16.

Complete response following toxic epidermal necrolysis in relapsed adult T cell leukemia/lymphoma after haploidentical stem cell transplantation.

Morishige S, Nishi M, Saruta H, Arakawa F, Yamasaki Y, Oya S, Nakamura T, Seki R, Yamaguchi M, Aoyama K, Mouri F, Osaki K, Ohshima K, Nagafuji K.

Int J Hematol. 2019 Oct;110(4):506-511. doi: 10.1007/s12185-019-02675-1. Epub 2019 May 31.

PMID:
31152415
17.

Classification for invasion depth of esophageal squamous cell carcinoma using a deep neural network compared with experienced endoscopists.

Nakagawa K, Ishihara R, Aoyama K, Ohmori M, Nakahira H, Matsuura N, Shichijo S, Nishida T, Yamada T, Yamaguchi S, Ogiyama H, Egawa S, Kishida O, Tada T.

Gastrointest Endosc. 2019 Sep;90(3):407-414. doi: 10.1016/j.gie.2019.04.245. Epub 2019 May 8.

PMID:
31077698
18.

The myeloid differentiation factor 88 signaling in donor T cells accelerates graft-versus-host disease.

Matsuoka S, Hashimoto D, Kadowaki M, Ohigashi H, Hayase E, Yokoyama E, Hasegawa Y, Tateno T, Chen X, Aoyama K, Oka H, Onozawa M, Takeda K, Akashi K, Teshima T.

Haematologica. 2019 May 2. pii: haematol.2018.203380. doi: 10.3324/haematol.2018.203380. [Epub ahead of print]

19.

Application of convolutional neural networks for evaluating Helicobacter pylori infection status on the basis of endoscopic images.

Shichijo S, Endo Y, Aoyama K, Takeuchi Y, Ozawa T, Takiyama H, Matsuo K, Fujishiro M, Ishihara S, Ishihara R, Tada T.

Scand J Gastroenterol. 2019 Feb;54(2):158-163. doi: 10.1080/00365521.2019.1577486. Epub 2019 Mar 17.

PMID:
30879352
20.

PD-L1 expression combined with microsatellite instability/CD8+ tumor infiltrating lymphocytes as a useful prognostic biomarker in gastric cancer.

Morihiro T, Kuroda S, Kanaya N, Kakiuchi Y, Kubota T, Aoyama K, Tanaka T, Kikuchi S, Nagasaka T, Nishizaki M, Kagawa S, Tazawa H, Fujiwara T.

Sci Rep. 2019 Mar 15;9(1):4633. doi: 10.1038/s41598-019-41177-2.

21.

Role for tyrosine phosphorylation of SUV39H1 histone methyltransferase in enhanced trimethylation of histone H3K9 via neuregulin-1/ErbB4 nuclear signaling.

Nakajo H, Ishibashi K, Aoyama K, Kubota S, Hasegawa H, Yamaguchi N, Yamaguchi N.

Biochem Biophys Res Commun. 2019 Apr 16;511(4):765-771. doi: 10.1016/j.bbrc.2019.02.130. Epub 2019 Mar 2.

PMID:
30833073
22.

PARP1 inhibition alleviates injury in ARH3-deficient mice and human cells.

Mashimo M, Bu X, Aoyama K, Kato J, Ishiwata-Endo H, Stevens LA, Kasamatsu A, Wolfe LA, Toro C, Adams D, Markello T, Gahl WA, Moss J.

JCI Insight. 2019 Feb 21;4(4). pii: 124519. doi: 10.1172/jci.insight.124519. eCollection 2019 Feb 21.

23.

[A Case of Gastric Small Cell Carcinoma with Rapid Regrowth after Surgery].

Watanabe M, Miyake T, Mikane Y, Syoji R, Kajiwara Y, Aoyama K, Nogami T, Nishikawa H, Shinoura S, Shigemitsu K, Nonaka Y, Hayashi D.

Gan To Kagaku Ryoho. 2019 Jan;46(1):145-147. Japanese.

PMID:
30765669
24.

Design, Synthesis, and Evaluation of (4 R)-1-{3-[2-(18F)Fluoro-4-methylpyridin-3-yl]phenyl}-4-[4-(1,3-thiazol-2-ylcarbonyl)piperazin-1-yl]pyrrolidin-2-one ([18F]T-401) as a Novel Positron-Emission Tomography Imaging Agent for Monoacylglycerol Lipase.

Hattori Y, Aoyama K, Maeda J, Arimura N, Takahashi Y, Sasaki M, Fujinaga M, Seki C, Nagai Y, Kawamura K, Yamasaki T, Zhang MR, Higuchi M, Koike T.

J Med Chem. 2019 Mar 14;62(5):2362-2375. doi: 10.1021/acs.jmedchem.8b01576. Epub 2019 Feb 26.

PMID:
30753069
25.

[A Case of Long-Term Disease-Free Survival of a Gastric Cancer Patient with Peritoneal Dissemination and Transverse Colon Invasion].

Kajiwara Y, Aoyama K, Mikane Y, Shoji R, Watanabe M, Nogami T, Nishikawa H, Shinoura S, Shigemitsu K, Nonaka Y, Hayashi D, Tokuda N, Miyake T.

Gan To Kagaku Ryoho. 2018 Dec;45(13):2461-2463. Japanese.

PMID:
30692498
26.

Trousseau syndrome in a patient with advanced oral squamous cell carcinoma: a case report.

Aoyama KI, Tamura M, Uchibori M, Nakanishi Y, Arai T, Aoki T, Osawa Y, Kaneko A, Ota Y.

J Med Case Rep. 2019 Jan 29;13(1):26. doi: 10.1186/s13256-018-1833-6.

27.

Automatic detection of erosions and ulcerations in wireless capsule endoscopy images based on a deep convolutional neural network.

Aoki T, Yamada A, Aoyama K, Saito H, Tsuboi A, Nakada A, Niikura R, Fujishiro M, Oka S, Ishihara S, Matsuda T, Tanaka S, Koike K, Tada T.

Gastrointest Endosc. 2019 Feb;89(2):357-363.e2. doi: 10.1016/j.gie.2018.10.027. Epub 2018 Oct 25.

PMID:
30670179
28.

Genetic and transcriptional landscape of plasma cells in POEMS syndrome.

Nagao Y, Mimura N, Takeda J, Yoshida K, Shiozawa Y, Oshima M, Aoyama K, Saraya A, Koide S, Rizq O, Hasegawa Y, Shiraishi Y, Chiba K, Tanaka H, Nishijima D, Isshiki Y, Kayamori K, Kawajiri-Manako C, Oshima-Hasegawa N, Tsukamoto S, Mitsukawa S, Takeda Y, Ohwada C, Takeuchi M, Iseki T, Misawa S, Miyano S, Ohara O, Yokote K, Sakaida E, Kuwabara S, Sanada M, Iwama A, Ogawa S, Nakaseko C.

Leukemia. 2019 Jul;33(7):1723-1735. doi: 10.1038/s41375-018-0348-x. Epub 2019 Jan 11.

PMID:
30635632
29.

Diagnosis using deep-learning artificial intelligence based on the endocytoscopic observation of the esophagus.

Kumagai Y, Takubo K, Kawada K, Aoyama K, Endo Y, Ozawa T, Hirasawa T, Yoshio T, Ishihara S, Fujishiro M, Tamaru JI, Mochiki E, Ishida H, Tada T.

Esophagus. 2019 Apr;16(2):180-187. doi: 10.1007/s10388-018-0651-7. Epub 2018 Dec 13.

PMID:
30547352
30.

Risk prediction models for maternal mortality: A systematic review and meta-analysis.

Aoyama K, D'Souza R, Pinto R, Ray JG, Hill A, Scales DC, Lapinsky SE, Seaward GR, Hladunewich M, Shah PS, Fowler RA.

PLoS One. 2018 Dec 4;13(12):e0208563. doi: 10.1371/journal.pone.0208563. eCollection 2018.

31.

Speech Recognition in Noise in Adults and Children Who Speak English or Chinese as Their First Language.

Schafer EC, Aoyama K, Ho T, Castillo P, Conlin J, Jones J, Thompson S.

J Am Acad Audiol. 2018 Nov/Dec;29(10):885-897. doi: 10.3766/jaaa.17066.

PMID:
30479261
32.

Ezh1 Targets Bivalent Genes to Maintain Self-Renewing Stem Cells in Ezh2-Insufficient Myelodysplastic Syndrome.

Aoyama K, Oshima M, Koide S, Suzuki E, Mochizuki-Kashio M, Kato Y, Tara S, Shinoda D, Hiura N, Nakajima-Takagi Y, Sashida G, Iwama A.

iScience. 2018 Nov 30;9:161-174. doi: 10.1016/j.isci.2018.10.008. Epub 2018 Oct 15.

33.

To what extent does the EQ-5D-3L correlate with the FACT-H&N of patients with oral cancer during the perioperative period?

Aoki T, Ota Y, Sasaki M, Aoyama KI, Akiba T, Shirasugi Y, Naito M, Shiroiwa T.

Int J Clin Oncol. 2019 Apr;24(4):350-358. doi: 10.1007/s10147-018-1364-6. Epub 2018 Nov 3.

PMID:
30392116
34.

Temporal Variations in Incidence andOutcomes of Critical Illness Among Pregnant and Postpartum Women inCanada: A Population-Based Observational Study.

Aoyama K, Ray JG, Pinto R, Hill A, Scales DC, Lapinsky SE, Fowler RA.

J Obstet Gynaecol Can. 2019 May;41(5):631-640. doi: 10.1016/j.jogc.2018.07.021. Epub 2018 Oct 29.

PMID:
30385209
35.

Renal effects of sodium glucose co-transporter 2 inhibitors in Japanese type 2 diabetes mellitus patients with home blood pressure monitoring.

Kobayashi K, Toyoda M, Kimura M, Hatori N, Furuki T, Sakai H, Takihata M, Umezono T, Ito S, Suzuki D, Takeda H, Kanamori A, Degawa H, Yamamoto H, Machimura H, Mokubo A, Chin K, Obana M, Hishiki T, Aoyama K, Nakajima S, Umezawa S, Shimura H, Aoyama T, Sato K, Miyakawa M.

Clin Exp Hypertens. 2019;41(7):637-644. doi: 10.1080/10641963.2018.1529778. Epub 2018 Oct 29.

PMID:
30373408
36.

Novel computer-assisted diagnosis system for endoscopic disease activity in patients with ulcerative colitis.

Ozawa T, Ishihara S, Fujishiro M, Saito H, Kumagai Y, Shichijo S, Aoyama K, Tada T.

Gastrointest Endosc. 2019 Feb;89(2):416-421.e1. doi: 10.1016/j.gie.2018.10.020. Epub 2018 Oct 24.

PMID:
30367878
37.

Circumstances of La, Eu, Dy, and Yb Cations Intercalated via Ion Exchange in γ-Zirconium Phosphate.

Takei T, Aoyama K, Yanagida S, Kumada N, Nakajima Y.

Inorg Chem. 2018 Nov 5;57(21):13097-13103. doi: 10.1021/acs.inorgchem.8b01003. Epub 2018 Oct 11.

PMID:
30351093
38.

Salt and marine products in the Classic Maya economy from use-wear study of stone tools.

McKillop H, Aoyama K.

Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):10948-10952. doi: 10.1073/pnas.1803639115. Epub 2018 Oct 8.

39.

Retrospective analysis of effects of sodium-glucose co-transporter 2 inhibitor in Japanese type 2 diabetes mellitus patients with chronic kidney disease.

Kobayashi K, Toyoda M, Kimura M, Hatori N, Furuki T, Sakai H, Takihata M, Umezono T, Ito S, Suzuki D, Takeda H, Kanamori A, Degawa H, Yamamoto H, Machimura H, Mokubo A, Chin K, Obana M, Hishiki T, Aoyama K, Nakajima S, Umezawa S, Shimura H, Aoyama T, Sato K, Miyakawa M.

Diab Vasc Dis Res. 2019 Jan;16(1):103-107. doi: 10.1177/1479164118802759. Epub 2018 Oct 4.

PMID:
30284913
40.

Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors.

Aida J, Fushimi M, Kusumoto T, Sugiyama H, Arimura N, Ikeda S, Sasaki M, Sogabe S, Aoyama K, Koike T.

J Med Chem. 2018 Oct 25;61(20):9205-9217. doi: 10.1021/acs.jmedchem.8b00824. Epub 2018 Oct 10.

PMID:
30251836
41.

Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome.

Tara S, Isshiki Y, Nakajima-Takagi Y, Oshima M, Aoyama K, Tanaka T, Shinoda D, Koide S, Saraya A, Miyagi S, Manabe I, Matsui H, Koseki H, Bardwell VJ, Iwama A.

Blood. 2018 Dec 6;132(23):2470-2483. doi: 10.1182/blood-2018-01-827964. Epub 2018 Sep 18.

PMID:
30228234
42.

Forkhead box protein A1 confers resistance to transforming growth factor-β-induced apoptosis in breast cancer cells through inhibition of Smad3 nuclear translocation.

Hirata K, Takakura Y, Shibazaki M, Morii M, Honda T, Oshima M, Aoyama K, Iwama A, Nakayama Y, Takano H, Yamaguchi N, Yamaguchi N.

J Cell Biochem. 2018 Sep 11. doi: 10.1002/jcb.27551. [Epub ahead of print]

PMID:
30206966
43.

Desuppression of TGF-β signaling via nuclear c-Abl-mediated phosphorylation of TIF1γ/TRIM33 at Tyr-524, -610, and -1048.

Yuki R, Tatewaki T, Yamaguchi N, Aoyama K, Honda T, Kubota S, Morii M, Manabe I, Kuga T, Tomonaga T, Yamaguchi N.

Oncogene. 2019 Jan;38(5):637-655. doi: 10.1038/s41388-018-0481-z. Epub 2018 Sep 3.

PMID:
30177833
44.

Diagnostic outcomes of esophageal cancer by artificial intelligence using convolutional neural networks.

Horie Y, Yoshio T, Aoyama K, Yoshimizu S, Horiuchi Y, Ishiyama A, Hirasawa T, Tsuchida T, Ozawa T, Ishihara S, Kumagai Y, Fujishiro M, Maetani I, Fujisaki J, Tada T.

Gastrointest Endosc. 2019 Jan;89(1):25-32. doi: 10.1016/j.gie.2018.07.037. Epub 2018 Aug 16.

PMID:
30120958
45.

Strategy of optical negative feedback for narrow linewidth semiconductor lasers.

Aoyama K, Yokota N, Yasaka H.

Opt Express. 2018 Aug 6;26(16):21159-21169. doi: 10.1364/OE.26.021159.

PMID:
30119420
46.

Ezh2 loss propagates hypermethylation at T cell differentiation-regulating genes to promote leukemic transformation.

Wang C, Oshima M, Sato D, Matsui H, Kubota S, Aoyama K, Nakajima-Takagi Y, Koide S, Matsubayashi J, Mochizuki-Kashio M, Nakano-Yokomizo T, Bai J, Nagao T, Kanai A, Iwama A, Sashida G.

J Clin Invest. 2018 Aug 31;128(9):3872-3886. doi: 10.1172/JCI94645. Epub 2018 Aug 6.

47.

Longitudinal changes in the quality of life of oral cancer patients during the perioperative period.

Aoki T, Ota Y, Suzuki T, Denda Y, Aoyama KI, Akiba T, Naito M, Arai T.

Int J Clin Oncol. 2018 Dec;23(6):1038-1045. doi: 10.1007/s10147-018-1322-3. Epub 2018 Jul 25.

PMID:
30047071
48.

HER2-targeted gold nanoparticles potentially overcome resistance to trastuzumab in gastric cancer.

Kubota T, Kuroda S, Kanaya N, Morihiro T, Aoyama K, Kakiuchi Y, Kikuchi S, Nishizaki M, Kagawa S, Tazawa H, Fujiwara T.

Nanomedicine. 2018 Aug;14(6):1919-1929. doi: 10.1016/j.nano.2018.05.019. Epub 2018 Jun 8.

PMID:
29885899
49.

Autologous Bone Marrow Transplantation for Polymyositis Combined with Myasthenia Gravis and Aplastic Anemia: A Case Report.

Mitsumune S, Manabe Y, Yunoki T, Kono S, Aoyama K, Shinno Y, Narai H, Abe K.

Case Rep Neurol. 2018 Apr 17;10(1):108-111. doi: 10.1159/000488476. eCollection 2018 Jan-Apr.

50.

Anti-inflammatory effects of heat-killed Lactobacillus plantarum L-137 on cardiac and adipose tissue in rats with metabolic syndrome.

Uchinaka A, Azuma N, Mizumoto H, Nakano S, Minamiya M, Yoneda M, Aoyama K, Komatsu Y, Yamada Y, Murohara T, Nagata K.

Sci Rep. 2018 May 25;8(1):8156. doi: 10.1038/s41598-018-26588-x.

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