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Items: 1 to 50 of 225

1.

YO-001A, a new antifungal agent produced by Streptomyces sp. YO15-A001.

Yamamoto K, Futamura Y, Uson-Lopez RA, Aono H, Shimizu T, Osada H.

J Antibiot (Tokyo). 2019 Dec;72(12):986-990. doi: 10.1038/s41429-019-0239-z. Epub 2019 Oct 10.

PMID:
31601980
2.

Structure and biological activity of Metarhizin C, a stereoisomer of BR-050 from Tolypocladium album RK17-F0007.

Nogawa T, Kawatani M, Okano A, Futamura Y, Aono H, Shimizu T, Kato N, Kikuchi H, Osada H.

J Antibiot (Tokyo). 2019 Dec;72(12):996-1000. doi: 10.1038/s41429-019-0229-1. Epub 2019 Sep 3.

PMID:
31481762
3.

IL-6-PAD4 axis in the earliest phase of arthritis in knock-in gp130F759 mice, a model for rheumatoid arthritis.

Yahagi A, Saika T, Hirano H, Takai-Imamura M, Tsuji F, Aono H, Iseki M, Morita Y, Igarashi H, Saeki Y, Ishihara K.

RMD Open. 2019 Jun 21;5(2):e000853. doi: 10.1136/rmdopen-2018-000853. eCollection 2019.

4.

Risk factors for a kyphosis recurrence after short-segment temporary posterior fixation for thoracolumbar burst fractures.

Aono H, Ishii K, Takenaka S, Tobimatsu H, Nagamoto Y, Horii C, Yamashita T, Furuya M, Iwasaki M.

J Clin Neurosci. 2019 Aug;66:138-143. doi: 10.1016/j.jocn.2019.04.035. Epub 2019 May 11.

PMID:
31088766
5.

Phase II trial of S-1 plus cisplatin combined with bevacizumab for advanced non-squamous non-small cell lung cancer (TCOG LC-1202).

Miyanaga A, Kubota K, Hosomi Y, Okuma Y, Minato K, Fujimoto S, Okamoto H, Satouchi M, Isobe H, Aono H, Takiguchi Y, Gemma A; Tokyo Cooperative Oncology Group.

Jpn J Clin Oncol. 2019 Aug 1;49(8):749-754. doi: 10.1093/jjco/hyz064.

PMID:
31070750
6.

A novel inhibitor of tumorspheres reveals the activation of the serine biosynthetic pathway upon mitochondrial inhibition.

Subedi A, Muroi M, Futamura Y, Kawamura T, Aono H, Nishi M, Ryo A, Watanabe N, Osada H.

FEBS Lett. 2019 Apr;593(8):763-776. doi: 10.1002/1873-3468.13361. Epub 2019 Mar 23.

PMID:
30874300
7.

Rapidly progressive miliary brain metastasis of lung cancer after EGFR tyrosine kinase inhibitor discontinuation: An autopsy report.

Kurihara M, Koda H, Aono H, Sugimoto I, Sakurai Y, Sano T, Saito Y, Murayama S, Mori M.

Neuropathology. 2019 Apr;39(2):147-155. doi: 10.1111/neup.12542. Epub 2019 Mar 13.

PMID:
30868686
8.

SPACIA1/SAAL1 Deletion Results in a Moderate Delay in Collagen-Induced Arthritis Activity, along with mRNA Decay of Cyclin-dependent Kinase 6 Gene.

Fujii R, Komatsu R, Sato T, Seki I, Konomi K, Aono H, Niki H, Yudoh K, Nishioka K, Nakajima T.

Int J Mol Sci. 2018 Nov 30;19(12). pii: E3828. doi: 10.3390/ijms19123828.

9.

Bioenergetic and proteomic profiling to screen small molecule inhibitors that target cancer metabolisms.

Futamura Y, Muroi M, Aono H, Kawatani M, Hayashida M, Sekine T, Nogawa T, Osada H.

Biochim Biophys Acta Proteins Proteom. 2019 Jan;1867(1):28-37. doi: 10.1016/j.bbapap.2018.06.001. Epub 2018 Jun 6.

PMID:
29883687
10.

Controllable Risk Factors for Neurologic Complications in Posterior Lumbar Interbody Fusion as Revision Surgery.

Yamashita T, Okuda S, Aono H, Matsumoto T, Maeno T, Sugiura T, Iwasaki M.

World Neurosurg. 2018 Aug;116:e1181-e1187. doi: 10.1016/j.wneu.2018.05.197. Epub 2018 Jun 2.

PMID:
29870848
11.

Achieving bioinspired flapping wing hovering flight solutions on Mars via wing scaling.

Bluman JE, Pohly JA, Sridhar MK, Kang CK, Landrum DB, Fahimi F, Aono H.

Bioinspir Biomim. 2018 Jun 26;13(4):046010. doi: 10.1088/1748-3190/aac876.

PMID:
29809163
12.

Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I.

Robke L, Futamura Y, Konstantinidis G, Wilke J, Aono H, Mahmoud Z, Watanabe N, Wu YW, Osada H, Laraia L, Waldmann H.

Chem Sci. 2018 Feb 26;9(11):3014-3022. doi: 10.1039/c7sc05040b. eCollection 2018 Mar 21.

13.

Catalytic Enantioselective Synthesis of a Pyrrolizidine-Alkaloid-Inspired Compound Collection with Antiplasmodial Activity.

Jia ZJ, Takayama H, Futamura Y, Aono H, Bauer JO, Strohmann C, Antonchick AP, Osada H, Waldmann H.

J Org Chem. 2018 Jul 6;83(13):7033-7041. doi: 10.1021/acs.joc.7b03202. Epub 2018 Feb 20.

PMID:
29460633
14.

Fusion Rate and Clinical Outcomes in Two-Level Posterior Lumbar Interbody Fusion.

Aono H, Takenaka S, Nagamoto Y, Tobimatsu H, Yamashita T, Furuya M, Iwasaki M.

World Neurosurg. 2018 Apr;112:e473-e478. doi: 10.1016/j.wneu.2018.01.062. Epub 2018 Jan 31.

PMID:
29355805
15.

Relationship between Pain and Functional Status in Patients with Amyotrophic Lateral Sclerosis: A Multicenter Cross-Sectional Study.

Ishida N, Hongo S, Kumano A, Hatta H, Zakoji N, Hirutani M, Yamamoto Y, Aono H, Tuigi M, Suzuki R, Hanamitsu H, Wakasugi E, Takahashi M, Yamatani A.

J Palliat Med. 2018 May;21(5):588-591. doi: 10.1089/jpm.2017.0503. Epub 2018 Jan 10.

PMID:
29319397
16.

Effects of spanwise flexibility on the performance of flapping flyers in forward flight.

Kodali D, Medina C, Kang CK, Aono H.

J R Soc Interface. 2017 Nov;14(136). pii: 20170725. doi: 10.1098/rsif.2017.0725.

17.

Postoperative Spinal Subdural Lesions Following Lumbar Spine Surgery: Prevalence and Risk Factors.

Nagamoto Y, Takenaka S, Aono H.

Asian Spine J. 2017 Oct;11(5):793-803. doi: 10.4184/asj.2017.11.5.793. Epub 2017 Oct 11.

18.

Microglia may compensate for dopaminergic neuron loss in experimental Parkinsonism through selective elimination of glutamatergic synapses from the subthalamic nucleus.

Aono H, Choudhury ME, Higaki H, Miyanishi K, Kigami Y, Fujita K, Akiyama JI, Takahashi H, Yano H, Kubo M, Nishikawa N, Nomoto M, Tanaka J.

Glia. 2017 Nov;65(11):1833-1847. doi: 10.1002/glia.23199. Epub 2017 Aug 24.

PMID:
28836295
19.

Temporary short-segment pedicle screw fixation for thoracolumbar burst fractures: comparative study with or without vertebroplasty.

Aono H, Ishii K, Tobimatsu H, Nagamoto Y, Takenaka S, Furuya M, Chiaki H, Iwasaki M.

Spine J. 2017 Aug;17(8):1113-1119. doi: 10.1016/j.spinee.2017.03.022. Epub 2017 Mar 31.

PMID:
28373079
20.

Mitochondrial uncoupler exerts a synthetic lethal effect against β-catenin mutant tumor cells.

Shikata Y, Kiga M, Futamura Y, Aono H, Inoue H, Kawada M, Osada H, Imoto M.

Cancer Sci. 2017 Apr;108(4):772-784. doi: 10.1111/cas.13172.

21.

Proteomic profiling reveals that collismycin A is an iron chelator.

Kawatani M, Muroi M, Wada A, Inoue G, Futamura Y, Aono H, Shimizu K, Shimizu T, Igarashi Y, Takahashi-Ando N, Osada H.

Sci Rep. 2016 Dec 6;6:38385. doi: 10.1038/srep38385.

22.

Prediction of Postoperative Clinical Recovery of Drop Foot Attributable to Lumbar Degenerative Diseases, via a Bayesian Network.

Takenaka S, Aono H.

Clin Orthop Relat Res. 2017 Mar;475(3):872-880. doi: 10.1007/s11999-016-5180-x. Epub 2016 Dec 2.

23.

Differences in the time of onset of postoperative upper limb palsy among surgical procedures: a meta-analysis.

Takenaka S, Nagamoto Y, Aono H, Kaito T, Hosono N.

Spine J. 2016 Dec;16(12):1486-1499. doi: 10.1016/j.spinee.2016.09.014. Epub 2016 Oct 8. Review.

PMID:
27725308
24.

Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival.

Kawamura T, Kawatani M, Muroi M, Kondoh Y, Futamura Y, Aono H, Tanaka M, Honda K, Osada H.

Sci Rep. 2016 May 23;6:26521. doi: 10.1038/srep26521.

25.

Identification of a novel compound that inhibits osteoclastogenesis by suppressing nucleoside transporters.

Katsuyama S, Sugino K, Sasazawa Y, Nakano Y, Aono H, Morishita K, Kawatani M, Umezawa K, Osada H, Simizu S.

FEBS Lett. 2016 Apr;590(8):1152-62. doi: 10.1002/1873-3468.12146. Epub 2016 Apr 3.

26.

Surgical outcomes of temporary short-segment instrumentation without augmentation for thoracolumbar burst fractures.

Aono H, Tobimatsu H, Ariga K, Kuroda M, Nagamoto Y, Takenaka S, Furuya M, Iwasaki M.

Injury. 2016 Jun;47(6):1337-44. doi: 10.1016/j.injury.2016.03.003. Epub 2016 Mar 12.

PMID:
26994520
27.

Changes in gene expression and cellular localization of insulin-like growth factors 1 and 2 in the ovaries during ovary development of the yellowtail, Seriola quinqueradiata.

Higuchi K, Gen K, Izumida D, Kazeto Y, Hotta T, Takashi T, Aono H, Soyano K.

Gen Comp Endocrinol. 2016 Jun 1;232:86-95. doi: 10.1016/j.ygcen.2016.01.002. Epub 2016 Jan 4.

PMID:
26764214
28.

Treadmill exercise ameliorates ischemia-induced brain edema while suppressing Na⁺/H⁺ exchanger 1 expression.

Nishioka R, Sugimoto K, Aono H, Mise A, Choudhury ME, Miyanishi K, Islam A, Fujita T, Takeda H, Takahashi H, Yano H, Tanaka J.

Exp Neurol. 2016 Mar;277:150-161. doi: 10.1016/j.expneurol.2015.12.016. Epub 2015 Dec 24.

PMID:
26724742
29.

Feasibility study of docetaxel plus bevacizumab as first line therapy for elderly patients with advanced non-small-cell lung cancer: Thoracic Oncology Research Group (TORG) 1014.

Takagi Y, Hosomi Y, Oshita F, Okamoto H, Seki N, Minato K, Aono H, Yamada K, Okuma Y, Hida N, Sakamoto T, Miura Y, Yomota M, Satoh A, Kunitoh H, Sakamaki K, Shibuya M, Watanabe K.

BMC Cancer. 2015 Oct 19;15:740. doi: 10.1186/s12885-015-1756-1.

30.

Results of second-stage screening for skin cancers in Oita Prefecture, Japan.

Kai Y, Ishikawa K, Goto M, Sakai T, Ito A, Shono T, Shimada H, Shimizu F, Goto M, Hatano Y, Okamoto O, Katagiri K, Aono H, Eshima N, Fujiwara S.

J Dermatol. 2015 Dec;42(12):1160-4. doi: 10.1111/1346-8138.13016. Epub 2015 Jul 16.

PMID:
26177589
31.

A prospective, multicentre phase II trial of low-dose erlotinib in non-small cell lung cancer patients with EGFR mutations pretreated with chemotherapy: Thoracic Oncology Research Group 0911.

Yamada K, Aono H, Hosomi Y, Okamoto H, Kato T, Komase Y, Nishikawa M, Azuma K, Takeoka H, Okuma Y, Nakahara Y, Sato A, Oba MS, Morita S, Kunitoh H, Watanabe K.

Eur J Cancer. 2015 Sep;51(14):1904-10. doi: 10.1016/j.ejca.2015.06.120. Epub 2015 Jul 11.

PMID:
26174465
32.

CD200+ and CD200- macrophages accumulated in ischemic lesions of rat brain: the two populations cannot be classified as either M1 or M2 macrophages.

Matsumoto S, Tanaka J, Yano H, Takahashi H, Sugimoto K, Ohue S, Inoue A, Aono H, Kusakawa A, Watanabe H, Kumon Y, Ohnishi T.

J Neuroimmunol. 2015 May 15;282:7-20. doi: 10.1016/j.jneuroim.2015.03.013. Epub 2015 Mar 14.

PMID:
25903723
33.

Saireito (TJ-114), a Japanese traditional herbal medicine, reduces 5-fluorouracil-induced intestinal mucositis in mice by inhibiting cytokine-mediated apoptosis in intestinal crypt cells.

Kato S, Hayashi S, Kitahara Y, Nagasawa K, Aono H, Shibata J, Utsumi D, Amagase K, Kadowaki M.

PLoS One. 2015 Jan 7;10(1):e0116213. doi: 10.1371/journal.pone.0116213. eCollection 2015.

34.

Surgical outcomes for painless drop foot due to degenerative lumbar disorders.

Aono H, Nagamoto Y, Tobimatsu H, Takenaka S, Iwasaki M.

J Spinal Disord Tech. 2014 Oct;27(7):E258-61. doi: 10.1097/BSD.0000000000000102.

PMID:
24905505
35.

Type 1 Achilles tendon rupture caused by grooming trauma in a young dog.

Isaka M, Befu M, Matsubara N, Ishikawa M, Aono H, Namba S.

Open Vet J. 2014;4(1):56-8. Epub 2014 May 2.

36.

Mitigation of chromatography adsorbent lot performance variability through control of buffer solution design space.

Aono H, Iliescu I, Cecchini D, Wood S, McCue JT.

J Chromatogr A. 2013 Nov 29;1318:198-206. doi: 10.1016/j.chroma.2013.10.019. Epub 2013 Oct 15.

PMID:
24169043
37.

Identification of a molecular target of a novel fungal metabolite, pyrrolizilactone, by phenotypic profiling systems.

Futamura Y, Kawatani M, Muroi M, Aono H, Nogawa T, Osada H.

Chembiochem. 2013 Dec 16;14(18):2456-63. doi: 10.1002/cbic.201300499. Epub 2013 Oct 25.

PMID:
24166831
38.

Characteristics of lipid and fatty acid of marine gastropod Turbo cornutus: high levels of arachidonic and n-3 docosapentaenoic acid.

Saito H, Aono H.

Food Chem. 2014 Feb 15;145:135-44. doi: 10.1016/j.foodchem.2013.08.011. Epub 2013 Aug 11.

PMID:
24128459
39.

Primary amyloidoma in epidural and paravertebral space of the lumbar spine.

Aono H, Kakunaga S, Koide S, Tobimatsu H, Kuroda M, Kudawara I, Mori K, Konishi E, Ueda T.

Spine J. 2013 Oct;13(10):e27-30. doi: 10.1016/j.spinee.2013.05.051. Epub 2013 Jul 23.

PMID:
23890946
40.

Pyrrolizilactone, a new pyrrolizidinone metabolite produced by a fungus.

Nogawa T, Kawatani M, Uramoto M, Okano A, Aono H, Futamura Y, Koshino H, Takahashi S, Osada H.

J Antibiot (Tokyo). 2013 Oct;66(10):621-3. doi: 10.1038/ja.2013.55. Epub 2013 May 29. No abstract available.

PMID:
23715039
41.

Isolation of new polyketide metabolites, linearolides A and B, from Streptomyces sp. RK95-74.

Ueki M, Koshiro N, Aono H, Kawatani M, Uramoto M, Kawasaki H, Osada H.

J Antibiot (Tokyo). 2013 Jun;66(6):333-7. doi: 10.1038/ja.2013.19. Epub 2013 Mar 27.

42.

Three-dimensional and multienergy gamma-ray simultaneous imaging by using a Si/CdTe Compton camera.

Suzuki Y, Yamaguchi M, Odaka H, Shimada H, Yoshida Y, Torikai K, Satoh T, Arakawa K, Kawachi N, Watanabe S, Takeda S, Ishikawa SN, Aono H, Watanabe S, Takahashi T, Nakano T.

Radiology. 2013 Jun;267(3):941-7. doi: 10.1148/radiol.13121194. Epub 2013 Feb 15.

PMID:
23418002
43.

Heat generation and transfer behaviors of ti-coated carbon steel rod adaptable for ablation therapy of oral cancer.

Naohara T, Aono H, Maehara T, Hirazawa H, Matsutomo S, Watanabe Y.

J Funct Biomater. 2013 Feb 18;4(1):27-37. doi: 10.3390/jfb4010027.

45.

Bucillamine inhibits CD40-mediated Akt activation and antibody production in mouse B-cell lymphoma.

Tsuji F, Setoguchi C, Okamoto M, Seki I, Sasano M, Aono H.

Int Immunopharmacol. 2012 Sep;14(1):47-53. doi: 10.1016/j.intimp.2012.06.012. Epub 2012 Jun 23.

PMID:
22735757
46.

[Initial clinical experience of early cardiac rehabilitation for very elderly patients over 85 years old following open heart surgery].

Furukawa H, Kangai K, Minami K, Ohura K, Ochi Y, Ikumoto H, Fujimoto M, Aono H, Samukawa M.

Kyobu Geka. 2012 Jun;65(6):440-5. Japanese.

PMID:
22647324
47.

[Open heart surgery in a patient with a history of Takotsubo cardiomyopathy].

Furukawa H, Aono H, Samukawa M, Ichikawa S.

Kyobu Geka. 2012 Feb;65(2):136-40. Japanese.

PMID:
22314170
48.

Development of ti-coated ferromagnetic needle, adaptable for ablation cancer therapy by high-frequency induction heating.

Naohara T, Aono H, Maehara T, Hirazawa H, Matsutomo S, Watanabe Y.

J Funct Biomater. 2012 Mar 6;3(1):163-72. doi: 10.3390/jfb3010163.

49.

Role of transient receptor potential vanilloid 1 in inflammation and autoimmune diseases.

Tsuji F, Aono H.

Pharmaceuticals (Basel). 2012 Aug 17;5(8):837-52. doi: 10.3390/ph5080837.

50.

Overexpression of SPACIA1/SAAL1, a newly identified gene that is involved in synoviocyte proliferation, accelerates the progression of synovitis in mice and humans.

Sato T, Fujii R, Konomi K, Yagishita N, Aratani S, Araya N, Aono H, Yudoh K, Suzuki N, Beppu M, Yamano Y, Nishioka K, Nakajima T.

Arthritis Rheum. 2011 Dec;63(12):3833-42. doi: 10.1002/art.30617.

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