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Items: 1 to 50 of 450

1.

Photo-immune therapy with liposomally formulated phospholipid-conjugated indocyanine green induces specific antitumor responses with heat shock protein-70 expression in a glioblastoma model.

Shibata S, Shinozaki N, Suganami A, Ikegami S, Kinoshita Y, Hasegawa R, Kentaro H, Okamoto Y, Aoki I, Tamura Y, Iwadate Y.

Oncotarget. 2019 Jan 4;10(2):175-183. doi: 10.18632/oncotarget.26544. eCollection 2019 Jan 4.

2.

Prenatal Irradiation-Induced Hippocampal Abnormalities in Rats Evaluated Using Manganese-Enhanced MRI.

Saito S, Sawada K, Aoki I.

Front Neural Circuits. 2018 Dec 17;12:112. doi: 10.3389/fncir.2018.00112. eCollection 2018.

3.

Isotropic 25-Micron 3D Neuroimaging Using ex vivo Microstructural Manganese-Enhanced MRI (MEMRI).

Sato C, Sawada K, Wright D, Higashi T, Aoki I.

Front Neural Circuits. 2018 Dec 6;12:110. doi: 10.3389/fncir.2018.00110. eCollection 2018.

4.

Comparison of diffusion-weighted MRI and anti-Stokes Raman scattering (CARS) measurements of the inter-compartmental exchange-time of water in expression-controlled aquaporin-4 cells.

Obata T, Kershaw J, Tachibana Y, Miyauchi T, Abe Y, Shibata S, Kawaguchi H, Ikoma Y, Takuwa H, Aoki I, Yasui M.

Sci Rep. 2018 Dec 18;8(1):17954. doi: 10.1038/s41598-018-36264-9.

5.

Atypical Protein Kinase C λ/ι Expression Is Associated with Malignancy of Oral Squamous Cell Carcinoma.

Baba J, Kioi M, Akimoto K, Nagashima Y, Taguri M, Inayama Y, Aoki I, Ohno S, Mitsudo K, Tohnai I.

Anticancer Res. 2018 Nov;38(11):6291-6297. doi: 10.21873/anticanres.12985.

PMID:
30396949
6.

Anti-Erosive Effect of Solutions Containing Sodium Fluoride, Stannous Chloride, and Selected Film-Forming Polymers.

Bezerra SJC, João-Souza SH, Aoki IV, Borges AB, Hara AT, Scaramucci T.

Caries Res. 2018 Oct 25;53(3):305-313. doi: 10.1159/000493388. [Epub ahead of print]

PMID:
30359980
7.

Fluorescence Tumor-Imaging Using a Thermo-Responsive Molecule with an Emissive Aminoquinoline Derivative.

Araki T, Fuchi Y, Murayama S, Shiraishi R, Oyama T, Aso M, Aoki I, Kobayashi S, Yamada KI, Karasawa S.

Nanomaterials (Basel). 2018 Oct 2;8(10). pii: E782. doi: 10.3390/nano8100782.

8.

SLO potassium channels antagonize premature decision making in C. elegans.

Aoki I, Tateyama M, Shimomura T, Ihara K, Kubo Y, Nakano S, Mori I.

Commun Biol. 2018 Aug 24;1:123. doi: 10.1038/s42003-018-0124-5. eCollection 2018.

9.

GWAS-identified CCR1 and IL10 loci contribute to M1 macrophage-predominant inflammation in Behçet's disease.

Nakano H, Kirino Y, Takeno M, Higashitani K, Nagai H, Yoshimi R, Yamaguchi Y, Kato I, Aoki I, Nakajima H.

Arthritis Res Ther. 2018 Jun 12;20(1):124. doi: 10.1186/s13075-018-1613-0.

10.

Treatment of oral cancer using magnetized paclitaxel.

Nakakaji R, Umemura M, Mitsudo K, Kim JH, Hoshino Y, Sato I, Masuda T, Yamamoto M, Kioi M, Koizumi T, Fujita T, Yokoyama U, Iida M, Sato M, Sato H, Murofushi S, Shibata S, Aoki I, Eguchi H, Tohnai I, Ishikawa Y.

Oncotarget. 2018 Feb 26;9(21):15591-15605. doi: 10.18632/oncotarget.24570. eCollection 2018 Mar 20.

11.

Dysregulated heme oxygenase-1low M2-like macrophages augment lupus nephritis via Bach1 induced by type I interferons.

Kishimoto D, Kirino Y, Tamura M, Takeno M, Kunishita Y, Takase-Minegishi K, Nakano H, Kato I, Nagahama K, Yoshimi R, Igarashi K, Aoki I, Nakajima H.

Arthritis Res Ther. 2018 Apr 10;20(1):64. doi: 10.1186/s13075-018-1568-1.

12.

Intratumoral evaluation of 3D microvasculature and nanoparticle distribution using a gadolinium-dendron modified nano-liposomal contrast agent with magnetic resonance micro-imaging.

Nitta N, Takakusagi Y, Kokuryo D, Shibata S, Tomita A, Higashi T, Aoki I, Harada M.

Nanomedicine. 2018 Apr 4;14(4):1315-1324. doi: 10.1016/j.nano.2018.03.006. [Epub ahead of print]

13.

Vitamin K: Redox-modulation, prevention of mitochondrial dysfunction and anticancer effect.

Ivanova D, Zhelev Z, Getsov P, Nikolova B, Aoki I, Higashi T, Bakalova R.

Redox Biol. 2018 Jun;16:352-358. doi: 10.1016/j.redox.2018.03.013. Epub 2018 Mar 20. Review.

14.

New Hypothesis and Alternative Approach for Imaging Neuronal Function and Metabolic Activity Based on Redox-Status

Getsov P, Zhelev Z, Aoki I, Bakalova R.

Balkan Med J. 2018 May 29;35(3):289-291. doi: 10.4274/balkanmedj.2018.0286. Epub 2018 Mar 28. No abstract available.

15.

Vitamins C and K3: A Powerful Redox System for Sensitizing Leukemia Lymphocytes to Everolimus and Barasertib.

Ivanova D, Zhelev Z, Lazarova D, Getsov P, Bakalova R, Aoki I.

Anticancer Res. 2018 Mar;38(3):1407-1414.

PMID:
29491065
16.

Water Diffusion in the Brain of Chronic Hypoperfusion Model Mice: A Study Considering the Effect of Blood Flow.

Urushihata T, Takuwa H, Seki C, Tachibana Y, Takahashi M, Kershaw J, Takado Y, Aoki I, Higuchi M, Ito H, Obata T.

Magn Reson Med Sci. 2018 Oct 10;17(4):318-324. doi: 10.2463/mrms.mp.2017-0149. Epub 2018 Feb 13.

17.

An in vitro study on the influence of viscosity and frequency of application of fluoride/tin solutions on the progression of erosion of bovine enamel.

Sakae LO, Bezerra SJC, João-Souza SH, Borges AB, Aoki IV, Aranha ACC, Scaramucci T.

Arch Oral Biol. 2018 May;89:26-30. doi: 10.1016/j.archoralbio.2018.01.017. Epub 2018 Feb 3.

PMID:
29425811
18.

Comparative In Vitro and In Vivo Quantifications of Pathologic Tau Deposits and Their Association with Neurodegeneration in Tauopathy Mouse Models.

Ni R, Ji B, Ono M, Sahara N, Zhang MR, Aoki I, Nordberg A, Suhara T, Higuchi M.

J Nucl Med. 2018 Jun;59(6):960-966. doi: 10.2967/jnumed.117.201632. Epub 2018 Feb 1.

PMID:
29419480
19.

Loading Efficiency of Polymersomes with Contrast Agents and their Intracellular Delivery: Quantum Dots Versus Organic Dyes.

Semkova S, Nikolova B, Zhelev Z, Tsoneva I, Zlateva G, Aoki I, Bakalova R.

Anticancer Res. 2018 Feb;38(2):825-831.

PMID:
29374708
20.

Repeated photon and C-ion irradiations in vivo have different impact on alteration of tumor characteristics.

Sato K, Nitta N, Aoki I, Imai T, Shimokawa T.

Sci Rep. 2018 Jan 23;8(1):1458. doi: 10.1038/s41598-018-19422-x.

21.

In Vivo Visualization of Tau Accumulation, Microglial Activation, and Brain Atrophy in a Mouse Model of Tauopathy rTg4510.

Ishikawa A, Tokunaga M, Maeda J, Minamihisamatsu T, Shimojo M, Takuwa H, Ono M, Ni R, Hirano S, Kuwabara S, Ji B, Zhang MR, Aoki I, Suhara T, Higuchi M, Sahara N.

J Alzheimers Dis. 2018;61(3):1037-1052. doi: 10.3233/JAD-170509.

PMID:
29332041
22.

Longitudinal Diffusion Tensor Imaging Revealed Nerve Fiber Alterations in Aspm Mutated Microcephaly Model Mice.

Ogi H, Nitta N, Tando S, Fujimori A, Aoki I, Fushiki S, Itoh K.

Neuroscience. 2018 Feb 10;371:325-336. doi: 10.1016/j.neuroscience.2017.12.012. Epub 2017 Dec 16.

PMID:
29253521
23.

Feasibility of magnetic resonance redox imaging at low magnetic field: comparison at 1 T and 7 T.

Nakamura M, Shibata S, Yamasaki T, Ueno M, Nakanishi I, Matsumoto KI, Kamada T, Yamada KI, Aoki I.

Am J Transl Res. 2017 Oct 15;9(10):4481-4491. eCollection 2017.

24.

Impressive Suppression of Colon Cancer Growth by Triple Combination SN38/EF24/Melatonin: "Oncogenic" Versus "Onco-Suppressive" Reactive Oxygen Species.

Bakalova R, Zhelev Z, Shibata S, Nikolova B, Aoki I, Higashi T.

Anticancer Res. 2017 Oct;37(10):5449-5458.

PMID:
28982855
25.

Mitochondrial Dysfunction and Redox Imbalance as a Diagnostic Marker of "Free Radical Diseases".

Georgieva E, Ivanova D, Zhelev Z, Bakalova R, Gulubova M, Aoki I.

Anticancer Res. 2017 Oct;37(10):5373-5381. Review.

PMID:
28982845
26.

Biphasic aspect of sexually dimorphic ontogenetic trajectory of gyrification in the ferret cerebral cortex.

Sawada K, Aoki I.

Neuroscience. 2017 Nov 19;364:71-81. doi: 10.1016/j.neuroscience.2017.09.015. Epub 2017 Sep 19.

PMID:
28935238
27.

Water-Proton Relaxivities of Radical Nanoparticles Self-Assembled via Hydration or Dehydration Processes.

Morishita K, Okamoto Y, Murayama S, Usui K, Ohashi E, Hirai G, Aoki I, Karasawa S.

Langmuir. 2017 Aug 8;33(31):7810-7817. doi: 10.1021/acs.langmuir.7b01126. Epub 2017 Jul 24.

PMID:
28678510
28.

Lobular homology in cerebellar hemispheres of humans, non-human primates and rodents: a structural, axonal tracing and molecular expression analysis.

Luo Y, Fujita H, Nedelescu H, Biswas MS, Sato C, Ying S, Takahashi M, Akita K, Higashi T, Aoki I, Sugihara I.

Brain Struct Funct. 2017 Aug;222(6):2449-2472. doi: 10.1007/s00429-017-1436-9. Epub 2017 May 15. Review.

PMID:
28508291
29.

Understanding microstructure of the brain by comparison of neurite orientation dispersion and density imaging (NODDI) with transparent mouse brain.

Sato K, Kerever A, Kamagata K, Tsuruta K, Irie R, Tagawa K, Okazawa H, Arikawa-Hirasawa E, Nitta N, Aoki I, Aoki S.

Acta Radiol Open. 2017 Apr 17;6(4):2058460117703816. doi: 10.1177/2058460117703816. eCollection 2017 Apr.

30.

Evaluation of a combination tumor treatment using thermo-triggered liposomal drug delivery and carbon ion irradiation.

Kokuryo D, Aoki I, Yuba E, Kono K, Aoshima S, Kershaw J, Saga T.

Transl Res. 2017 Jul;185:24-33. doi: 10.1016/j.trsl.2017.04.001. Epub 2017 Apr 21.

31.

A polymeric micelle magnetic resonance imaging (MRI) contrast agent reveals blood-brain barrier (BBB) permeability for macromolecules in cerebral ischemia-reperfusion injury.

Shiraishi K, Wang Z, Kokuryo D, Aoki I, Yokoyama M.

J Control Release. 2017 May 10;253:165-171. doi: 10.1016/j.jconrel.2017.03.020. Epub 2017 Mar 18.

PMID:
28322975
32.

Self-Assembly Behavior of Emissive Urea Benzene Derivatives Enables Heat-Induced Accumulation in Tumor Tissue.

Araki T, Murayama S, Usui K, Shimada T, Aoki I, Karasawa S.

Nano Lett. 2017 Apr 12;17(4):2397-2403. doi: 10.1021/acs.nanolett.6b05371. Epub 2017 Mar 7.

PMID:
28264561
33.

Hyperthermia and chemotherapy using Fe(Salen) nanoparticles might impact glioblastoma treatment.

Ohtake M, Umemura M, Sato I, Akimoto T, Oda K, Nagasako A, Kim JH, Fujita T, Yokoyama U, Nakayama T, Hoshino Y, Ishiba M, Tokura S, Hara M, Muramoto T, Yamada S, Masuda T, Aoki I, Takemura Y, Murata H, Eguchi H, Kawahara N, Ishikawa Y.

Sci Rep. 2017 Feb 20;7:42783. doi: 10.1038/srep42783.

34.

Regional difference in sulcal infolding progression correlated with cerebral cortical expansion in cynomolgus monkey fetuses.

Sawada K, Fukunishi K, Kashima M, Imai N, Saito S, Aoki I, Fukui Y.

Congenit Anom (Kyoto). 2017 Jul;57(4):114-117. doi: 10.1111/cga.12209. Epub 2017 Mar 28.

PMID:
28109019
35.

Functional MRI of the Reserpine-Induced Putative Rat Model of Fibromyalgia Reveals Discriminatory Patterns of Functional Augmentation to Acute Nociceptive Stimuli.

Wells JA, Shibata S, Fujikawa A, Takahashi M, Saga T, Aoki I.

Sci Rep. 2017 Jan 12;7:38325. doi: 10.1038/srep38325.

36.

Synergistic Cytotoxicity of Melatonin and New-generation Anticancer Drugs Against Leukemia Lymphocytes But Not Normal Lymphocytes.

Zhelev Z, Ivanova D, Bakalova R, Aoki I, Higashi T.

Anticancer Res. 2017 Jan;37(1):149-159.

PMID:
28011485
37.

PET imaging-guided chemogenetic silencing reveals a critical role of primate rostromedial caudate in reward evaluation.

Nagai Y, Kikuchi E, Lerchner W, Inoue KI, Ji B, Eldridge MA, Kaneko H, Kimura Y, Oh-Nishi A, Hori Y, Kato Y, Hirabayashi T, Fujimoto A, Kumata K, Zhang MR, Aoki I, Suhara T, Higuchi M, Takada M, Richmond BJ, Minamimoto T.

Nat Commun. 2016 Dec 6;7:13605. doi: 10.1038/ncomms13605.

38.

Multimodal Imaging for DREADD-Expressing Neurons in Living Brain and Their Application to Implantation of iPSC-Derived Neural Progenitors.

Ji B, Kaneko H, Minamimoto T, Inoue H, Takeuchi H, Kumata K, Zhang MR, Aoki I, Seki C, Ono M, Tokunaga M, Tsukamoto S, Tanabe K, Shin RM, Minamihisamatsu T, Kito S, Richmond BJ, Suhara T, Higuchi M.

J Neurosci. 2016 Nov 9;36(45):11544-11558.

39.

Influence of bioadhesive polymers on the protective effect of fluoride against erosion.

Ávila DM, Zanatta RF, Scaramucci T, Aoki IV, Torres CR, Borges AB.

J Dent. 2017 Jan;56:45-52. doi: 10.1016/j.jdent.2016.10.015. Epub 2016 Oct 25.

PMID:
27793704
40.

Detection of Redox Imbalance in Normal Lymphocytes with Induced Mitochondrial Dysfunction - EPR Study.

Georgieva E, Zhelev Z, Aoki I, Bakalova R, Higashi T.

Anticancer Res. 2016 Oct;36(10):5273-5279.

PMID:
27798888
41.

Inhibition of the Pentose-phosphate Pathway Selectively Sensitizes Leukemia Lymphocytes to Chemotherapeutics by ROS-independent Mechanism.

Zhelev Z, Ivanova D, Bakalova R, Aoki I, Higashi T.

Anticancer Res. 2016 Nov;36(11):6011-6020.

PMID:
27793928
42.

Overproduction of reactive oxygen species - obligatory or not for induction of apoptosis by anticancer drugs.

Ivanova D, Zhelev Z, Aoki I, Bakalova R, Higashi T.

Chin J Cancer Res. 2016 Aug;28(4):383-96. doi: 10.21147/j.issn.1000-9604.2016.04.01.

43.

Electroinduced Delivery of Hydrogel Nanoparticles in Colon 26 Cells, Visualized by Confocal Fluorescence System.

Atanasova S, Nikolova B, Murayama S, Stoyanova E, Tsoneva I, Zhelev Z, Aoki I, Bakalova R.

Anticancer Res. 2016 Sep;36(9):4601-6.

PMID:
27630301
44.

Thermal- and pH-Dependent Size Variable Radical Nanoparticles and Its Water Proton Relaxivity for Metal-Free MRI Functional Contrast Agents.

Morishita K, Murayama S, Araki T, Aoki I, Karasawa S.

J Org Chem. 2016 Sep 16;81(18):8351-62. doi: 10.1021/acs.joc.6b01509. Epub 2016 Aug 31.

PMID:
27541011
45.

Nano-theranostics and Nitroxyl Radical-labeled Antitumor Agents for Magnetic Resonance Imaging.

Aoki I.

Yakugaku Zasshi. 2016;136(8):1087-91. doi: 10.1248/yakushi.15-00234-3. Review. Japanese.

46.

MRI of cerebral micro-vascular flow patterns: A multi-direction diffusion-weighted ASL approach.

Wells JA, Thomas DL, Saga T, Kershaw J, Aoki I.

J Cereb Blood Flow Metab. 2017 Jun;37(6):2076-2083. doi: 10.1177/0271678X16660985. Epub 2016 Jan 1.

47.

Accumulated α-synuclein affects the progression of GM2 gangliosidoses.

Suzuki K, Yamaguchi A, Yamanaka S, Kanzaki S, Kawashima M, Togo T, Katsuse O, Koumitsu N, Aoki N, Iseki E, Kosaka K, Yamaguchi K, Hashimoto M, Aoki I, Hirayasu Y.

Exp Neurol. 2016 Oct;284(Pt A):38-49. doi: 10.1016/j.expneurol.2016.07.011. Epub 2016 Jul 21.

PMID:
27453479
48.

FOSL1 immunohistochemistry clarifies the distinction between desmoplastic fibroblastoma and fibroma of tendon sheath.

Kato I, Yoshida A, Ikegami M, Okuma T, Tonooka A, Horiguchi S, Funata N, Kawai A, Goto T, Hishima T, Aoki I, Motoi T.

Histopathology. 2016 Dec;69(6):1012-1020. doi: 10.1111/his.13042. Epub 2016 Sep 27.

PMID:
27442992
49.

Preclinical and clinical results of dual orexin receptor antagonist, suvorexant (BELSOMRA(®)), a novel therapeutic agent for insomnia.

Tanaka Y, Aoki I, Ishine T, Renger JJ, Winrow CJ, Hisada S.

Nihon Yakurigaku Zasshi. 2016 Jul;148(1):46-56. doi: 10.1254/fpj.148.46. Review. Japanese. No abstract available.

PMID:
27430679
50.

M2-polarized macrophages contribute to neovasculogenesis, leading to relapse of oral cancer following radiation.

Okubo M, Kioi M, Nakashima H, Sugiura K, Mitsudo K, Aoki I, Taniguchi H, Tohnai I.

Sci Rep. 2016 Jun 8;6:27548. doi: 10.1038/srep27548.

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