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Items: 1 to 50 of 202

1.

Trans-resveratrol, but not other natural stilbenes occurring in food, carries the risk of drug-food interaction via inhibition of cytochrome P450 enzymes or interaction with xenosensor receptors.

Hyrsova L, Vanduchova A, Dusek J, Smutny T, Carazo A, Maresova V, Trejtnar F, Barta P, Anzenbacher P, Dvorak Z, Pavek P.

Toxicol Lett. 2018 Oct 27;300:81-91. doi: 10.1016/j.toxlet.2018.10.028. [Epub ahead of print]

PMID:
30394306
2.

Isothiocyanate from Broccoli, Sulforaphane, and Its Properties.

Vanduchova A, Anzenbacher P, Anzenbacherova E.

J Med Food. 2018 Oct 27. doi: 10.1089/jmf.2018.0024. [Epub ahead of print]

PMID:
30372361
3.

In vivo evaluation of effect of anthocyanin-rich wheat on rat liver microsomal drug-metabolizing cytochromes P450 and on biochemical and antioxidant parameters in rats.

Prokop J, Anzenbacher P, Mrkvicová E, Pavlata L, Zapletalová I, Šťastník O, Martinek P, Kosina P, Anzenbacherová E.

Food Chem Toxicol. 2018 Dec;122:225-233. doi: 10.1016/j.fct.2018.10.029. Epub 2018 Oct 11.

PMID:
30316842
4.

Membrane-attached mammalian cytochromes P450: An overview of the membrane's effects on structure, drug binding, and interactions with redox partners.

Šrejber M, Navrátilová V, Paloncýová M, Bazgier V, Berka K, Anzenbacher P, Otyepka M.

J Inorg Biochem. 2018 Jun;183:117-136. doi: 10.1016/j.jinorgbio.2018.03.002. Epub 2018 Mar 5. Review.

5.

Anion Sensing by Fluorescent Expanded Calixpyrroles.

Pushina M, Koutnik P, Nishiyabu R, Minami T, Savechenkov P, Anzenbacher P Jr.

Chemistry. 2018 Apr 3;24(19):4879-4884. doi: 10.1002/chem.201705387. Epub 2018 Mar 6.

PMID:
29385284
6.

In vitro analysis of itraconazole cis-diastereoisomers inhibition of nine cytochrome P450 enzymes: stereoselective inhibition of CYP3A.

Krasulova K, Dvorak Z, Anzenbacher P.

Xenobiotica. 2018 Jan 22:1-7. doi: 10.1080/00498254.2018.1425510. [Epub ahead of print]

PMID:
29320899
7.

Influence of Amlodipine Enantiomers on Human Microsomal Cytochromes P450: Stereoselective Time-Dependent Inhibition of CYP3A Enzyme Activity.

Krasulova K, Holas O, Anzenbacher P.

Molecules. 2017 Nov 3;22(11). pii: E1879. doi: 10.3390/molecules22111879.

8.

The inhibitory effects of β-caryophyllene, β-caryophyllene oxide and α-humulene on the activities of the main drug-metabolizing enzymes in rat and human liver in vitro.

Nguyen LT, Myslivečková Z, Szotáková B, Špičáková A, Lněničková K, Ambrož M, Kubíček V, Krasulová K, Anzenbacher P, Skálová L.

Chem Biol Interact. 2017 Dec 25;278:123-128. doi: 10.1016/j.cbi.2017.10.021. Epub 2017 Oct 23.

PMID:
29074051
9.

Biguanides, anion receptors and sensors.

Pushina M, Anzenbacher P.

Chem Commun (Camb). 2017 Sep 5;53(72):10074-10077. doi: 10.1039/c7cc05012g.

PMID:
28848964
10.

Supramolecular Sensors for Opiates and Their Metabolites.

Shcherbakova EG, Zhang B, Gozem S, Minami T, Zavalij PY, Pushina M, Isaacs LD, Anzenbacher P Jr.

J Am Chem Soc. 2017 Oct 25;139(42):14954-14960. doi: 10.1021/jacs.7b06371. Epub 2017 Sep 8.

11.

Effects of obesity on liver cytochromes P450 in various animal models.

Tomankova V, Anzenbacher P, Anzenbacherova E.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2017 Jun;161(2):144-151. doi: 10.5507/bp.2017.026. Epub 2017 May 25.

12.

High-Throughput Assay for Enantiomeric Excess Determination in 1,2- and 1,3-Diols and Direct Asymmetric Reaction Screening.

Shcherbakova EG, Brega V, Lynch VM, James TD, Anzenbacher P Jr.

Chemistry. 2017 Jul 26;23(42):10222-10229. doi: 10.1002/chem.201701923. Epub 2017 Jul 6.

PMID:
28543938
13.

Toward wearable sensors: optical sensor for detection of ammonium nitrate-based explosives, ANFO and ANNM.

Sheykhi S, Mosca L, Anzenbacher P.

Chem Commun (Camb). 2017 May 4;53(37):5196-5199. doi: 10.1039/c7cc01949a.

PMID:
28443900
14.

Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions.

Špičáková A, Szotáková B, Dimunová D, Myslivečková Z, Kubíček V, Ambrož M, Lněničková K, Krasulová K, Anzenbacher P, Skálová L.

Molecules. 2017 Mar 24;22(4). pii: E509. doi: 10.3390/molecules22040509.

15.

Colonization by non-pathogenic bacteria alters mRNA expression of cytochromes P450 in originally germ-free mice.

Jourová L, Anzenbacher P, Lišková B, Matušková Z, Hermanová P, Hudcovic T, Kozáková H, Hrnčířová L, Anzenbacherová E.

Folia Microbiol (Praha). 2017 Nov;62(6):463-469. doi: 10.1007/s12223-017-0517-8. Epub 2017 Mar 23.

PMID:
28337589
16.

Influence of Sulforaphane Metabolites on Activities of Human Drug-Metabolizing Cytochrome P450 and Determination of Sulforaphane in Human Liver Cells.

Vanduchova A, Tomankova V, Anzenbacher P, Anzenbacherova E.

J Med Food. 2016 Dec;19(12):1141-1146. Epub 2016 Oct 25.

PMID:
27779894
17.

Optical isomers of dihydropyridine calcium channel blockers display enantiospecific effects on the expression and enzyme activities of human xenobiotics-metabolizing cytochromes P450.

Štěpánková M, Krasulová K, Dořičáková A, Kurka O, Anzenbacher P, Dvořák Z.

Toxicol Lett. 2016 Nov 16;262:173-186. doi: 10.1016/j.toxlet.2016.10.005. Epub 2016 Oct 11.

PMID:
27732883
18.

Bowl-shaped Tröger's bases and their recognition properties.

Mosca L, Čejka J, Dolenský B, Havlík M, Jakubek M, Kaplánek R, Král V, Anzenbacher P.

Chem Commun (Camb). 2016 Aug 23;52(70):10664-7. doi: 10.1039/c6cc05923f.

PMID:
27501993
19.

Human gut microbiota plays a role in the metabolism of drugs.

Jourova L, Anzenbacher P, Anzenbacherova E.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2016 Sep;160(3):317-26. doi: 10.5507/bp.2016.039. Epub 2016 Aug 2. Review.

20.

Detection and quantification of ATP in human blood serum.

Akdeniz A, Caglayan MG, Polivina I, Anzenbacher P.

Org Biomol Chem. 2016 Aug 21;14(31):7459-62. doi: 10.1039/c6ob01378c. Epub 2016 Jul 25.

PMID:
27454442
21.

Interaction of isoflavonoids with human liver microsomal cytochromes P450: inhibition of CYP enzyme activities.

Kopečná-Zapletalová M, Krasulová K, Anzenbacher P, Hodek P, Anzenbacherová E.

Xenobiotica. 2017 Apr;47(4):324-331. doi: 10.1080/00498254.2016.1195028. Epub 2016 Jun 17.

PMID:
27312150
22.

Fluorescent zinc and copper complexes for detection of adrafinil in paper-based microfluidic devices.

Caglayan MG, Sheykhi S, Mosca L, Anzenbacher P.

Chem Commun (Camb). 2016 Jul 7;52(53):8279-82. doi: 10.1039/c6cc03640f. Epub 2016 Jun 13.

PMID:
27293080
23.

Toward Fluorescence-Based High-Throughput Screening for Enantiomeric Excess in Amines and Amino Acid Derivatives.

Shcherbakova EG, Brega V, Minami T, Sheykhi S, James TD, Anzenbacher P Jr.

Chemistry. 2016 Jul 11;22(29):10074-80. doi: 10.1002/chem.201601614. Epub 2016 Jun 6.

PMID:
27271215
24.

Quantitative analysis of modeled ATP hydrolysis in water by a colorimetric sensor array.

Minami T, Emami F, Nishiyabu R, Kubo Y, Anzenbacher P.

Chem Commun (Camb). 2016 Jun 14;52(50):7838-41. doi: 10.1039/c6cc02923j.

PMID:
27241171
25.

Determination of enantiomeric excess of carboxylates by fluorescent macrocyclic sensors.

Akdeniz A, Minami T, Watanabe S, Yokoyama M, Ema T, Anzenbacher P Jr.

Chem Sci. 2016 Mar 1;7(3):2016-2022. doi: 10.1039/c5sc04235f. Epub 2015 Dec 14.

26.

The Role of Protein-Protein and Protein-Membrane Interactions on P450 Function.

Scott EE, Wolf CR, Otyepka M, Humphreys SC, Reed JR, Henderson CJ, McLaughlin LA, Paloncýová M, Navrátilová V, Berka K, Anzenbacher P, Dahal UP, Barnaba C, Brozik JA, Jones JP, Estrada DF, Laurence JS, Park JW, Backes WL.

Drug Metab Dispos. 2016 Apr;44(4):576-90. doi: 10.1124/dmd.115.068569. Epub 2016 Feb 5. Review.

27.

Specific features of pharmacokinetics in children.

Matalová P, Urbánek K, Anzenbacher P.

Drug Metab Rev. 2016;48(1):70-9. doi: 10.3109/03602532.2015.1135941. Epub 2016 Feb 1. Review.

PMID:
26828377
28.

Effect of Lactobacillus casei on the Pharmacokinetics of Amiodarone in Male Wistar Rats.

Matuskova Z, Anzenbacher P, Vecera R, Siller M, Tlaskalova-Hogenova H, Strojil J, Anzenbacherova E.

Eur J Drug Metab Pharmacokinet. 2017 Feb;42(1):29-36. doi: 10.1007/s13318-015-0315-0.

PMID:
26797809
29.

Evaluation of possible inhibition of human liver drug metabolizing cytochromes P450 by two new acetylcholinesterase oxime-type reactivators.

Spicakova A, Anzenbacher P, Liskova B, Kuca K, Fusek J, Anzenbacherova E.

Food Chem Toxicol. 2016 Feb;88:100-4. doi: 10.1016/j.fct.2015.11.024. Epub 2015 Dec 31.

PMID:
26747974
30.

Antibody- and Label-Free Phosphoprotein Sensor Device Based on an Organic Transistor.

Minamiki T, Minami T, Koutnik P, Anzenbacher P Jr, Tokito S.

Anal Chem. 2016 Jan 19;88(2):1092-5. doi: 10.1021/acs.analchem.5b04618. Epub 2016 Jan 4.

PMID:
26713563
31.

A tri-serine tri-lactone scaffold for the quantification of citrate in urine.

Akdeniz A, Caglayan MG, Anzenbacher P Jr.

Chem Commun (Camb). 2016 Jan 31;52(9):1827-30. doi: 10.1039/c5cc08759g.

PMID:
26669653
32.

A mercury(II) ion sensor device based on an organic field effect transistor with an extended-gate modified by dipicolylamine.

Minami T, Sasaki Y, Minamiki T, Koutnik P, Anzenbacher P Jr, Tokito S.

Chem Commun (Camb). 2015 Dec 28;51(100):17666-8. doi: 10.1039/c5cc07893h.

PMID:
26463465
33.

Enantiospecific effects of chiral drugs on cytochrome P450 inhibition in vitro.

Krasulova K, Siller M, Holas O, Dvorak Z, Anzenbacher P.

Xenobiotica. 2016;46(4):315-24. doi: 10.3109/00498254.2015.1076086. Epub 2015 Aug 24.

PMID:
26338061
34.

Small-Molecule Turn-On Fluorescent Probes for RDX.

Mosca L, Karimi Behzad S, Anzenbacher P Jr.

J Am Chem Soc. 2015 Jul 1;137(25):7967-9. doi: 10.1021/jacs.5b04643. Epub 2015 Jun 16.

PMID:
26074208
35.

Altered cytochrome P450 activities and expression levels in the liver and intestines of the monosodium glutamate-induced mouse model of human obesity.

Tomankova V, Liskova B, Skalova L, Bartikova H, Bousova I, Jourova L, Anzenbacher P, Ulrichova J, Anzenbacherova E.

Life Sci. 2015 Jul 15;133:15-20. doi: 10.1016/j.lfs.2015.04.014. Epub 2015 May 18.

PMID:
25998026
36.

Determination of enantiomeric excess in amine derivatives with molecular self-assemblies.

Shcherbakova EG, Minami T, Brega V, James TD, Anzenbacher P Jr.

Angew Chem Int Ed Engl. 2015 Jun 8;54(24):7130-3. doi: 10.1002/anie.201501736. Epub 2015 Apr 29.

PMID:
25925816
37.

Interaction of rocuronium with human liver cytochromes P450.

Anzenbacherova E, Spicakova A, Jourova L, Ulrichova J, Adamus M, Bachleda P, Anzenbacher P.

J Pharmacol Sci. 2015 Feb;127(2):190-5. doi: 10.1016/j.jphs.2014.12.006. Epub 2014 Dec 23.

38.

Sensing of enantiomeric excess in chiral carboxylic acids.

Akdeniz A, Mosca L, Minami T, Anzenbacher P Jr.

Chem Commun (Camb). 2015 Apr 4;51(26):5770-3. doi: 10.1039/c5cc00376h.

PMID:
25720499
39.

Cardiovascular effects of coumarins besides their antioxidant activity.

Najmanová I, Doseděl M, Hrdina R, Anzenbacher P, Filipský T, Říha M, Mladěnka P.

Curr Top Med Chem. 2015;15(9):830-49. Review.

PMID:
25697565
40.

Influence of diet supplementation with green tea extract on drug-metabolizing enzymes in a mouse model of monosodium glutamate-induced obesity.

Boušová I, Matoušková P, Bártíková H, Szotáková B, Hanušová V, Tománková V, Anzenbacherová E, Lišková B, Anzenbacher P, Skálová L.

Eur J Nutr. 2016 Feb;55(1):361-71. doi: 10.1007/s00394-015-0856-7. Epub 2015 Feb 8.

PMID:
25663641
41.

Sensing of 2,4,6-trinitrotoluene (TNT) and 2,4-dinitrotoluene (2,4-DNT) in the solid state with photoluminescent Ru(II) and Ir(III) complexes.

Mosca L, Khnayzer RS, Lazorski MS, Danilov EO, Castellano FN, Anzenbacher P Jr.

Chemistry. 2015 Mar 2;21(10):4056-64. doi: 10.1002/chem.201405717. Epub 2015 Jan 28.

PMID:
25631574
42.

Dual effects of ketoconazole cis-enantiomers on CYP3A4 in human hepatocytes and HepG2 Cells.

Novotná A, Krasulová K, Bartoňková I, Korhoňová M, Bachleda P, Anzenbacher P, Dvořák Z.

PLoS One. 2014 Oct 24;9(10):e111286. doi: 10.1371/journal.pone.0111286. eCollection 2014.

43.

Pressure effects reveal that changes in the redox states of the heme iron complexes in the sensor domains of two heme-based oxygen sensor proteins, EcDOS and YddV, have profound effects on their flexibility.

Anzenbacher P, Marchal S, Palacký J, Anzenbacherová E, Domaschke T, Lange R, Shimizu T, Kitanishi K, Stranava M, Stiborová M, Martinkova M.

FEBS J. 2014 Dec;281(23):5208-19. doi: 10.1111/febs.13060. Epub 2014 Oct 13.

44.

Benzimidazole derivatives: synthesis, physical properties, and n-type semiconducting properties.

Mamada M, Pérez-Bolívar C, Kumaki D, Esipenko NA, Tokito S, Anzenbacher P Jr.

Chemistry. 2014 Sep 8;20(37):11835-46. doi: 10.1002/chem.201403058. Epub 2014 Jul 30.

PMID:
25079856
45.

Intramolecular indicator displacement assay for anions: supramolecular sensor for glyphosate.

Minami T, Liu Y, Akdeniz A, Koutnik P, Esipenko NA, Nishiyabu R, Kubo Y, Anzenbacher P Jr.

J Am Chem Soc. 2014 Aug 13;136(32):11396-401. doi: 10.1021/ja504535q. Epub 2014 Jul 29.

PMID:
25051138
46.

Acyclic nucleoside phosphonates: a study on cytochrome P450 gene expression.

Nekvindova J, Contreras JA, Juvan P, Fon Tacer K, Anzenbacher P, Zidek Z, Kopecna Zapletalova M, Rozman D, Anzenbacherova E.

Xenobiotica. 2014 Aug;44(8):708-15. doi: 10.3109/00498254.2014.895880. Epub 2014 Mar 5.

PMID:
24593268
47.

Selective anion sensing by chiral macrocyclic receptors with multiple hydrogen-bonding sites.

Ema T, Okuda K, Watanabe S, Yamasaki T, Minami T, Esipenko NA, Anzenbacher P Jr.

Org Lett. 2014 Mar 7;16(5):1302-5. doi: 10.1021/ol403643d. Epub 2014 Feb 14.

PMID:
24528472
48.

Administration of a probiotic can change drug pharmacokinetics: effect of E. coli Nissle 1917 on amidarone absorption in rats.

Matuskova Z, Anzenbacherova E, Vecera R, Tlaskalova-Hogenova H, Kolar M, Anzenbacher P.

PLoS One. 2014 Feb 5;9(2):e87150. doi: 10.1371/journal.pone.0087150. eCollection 2014.

49.

Anion binding modes in meso-substituted hexapyrrolic calix[4]pyrrole isomers.

Chang KC, Minami T, Koutnik P, Savechenkov PY, Liu Y, Anzenbacher P Jr.

J Am Chem Soc. 2014 Jan 29;136(4):1520-5. doi: 10.1021/ja411391c. Epub 2014 Jan 17.

PMID:
24392650
50.

Effects of anthocyanidins and anthocyanins on the expression and catalytic activities of CYP2A6, CYP2B6, CYP2C9, and CYP3A4 in primary human hepatocytes and human liver microsomes.

Srovnalova A, Svecarova M, Zapletalova MK, Anzenbacher P, Bachleda P, Anzenbacherova E, Dvorak Z.

J Agric Food Chem. 2014 Jan 22;62(3):789-97. doi: 10.1021/jf404643w. Epub 2014 Jan 10.

PMID:
24387788

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