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Items: 1 to 50 of 287

1.

A human immortalized cell-based blood-brain barrier tri-culture model: development and characterization as a promising tool for drug brain permeability studies.

Ito R, Umehara K, Suzuki S, Kitamura K, Nunoya KI, Yamaura Y, Imawaka H, Izumi S, Wakayama N, Komori T, Anzai N, Akita H, Furihata T.

Mol Pharm. 2019 Oct 1. doi: 10.1021/acs.molpharmaceut.9b00519. [Epub ahead of print]

PMID:
31573814
2.

LAT1-specific inhibitor is effective against T cell-mediated allergic skin inflammation.

Hayashi K, Kaminuma O, Nishimura T, Saeki M, Matsuoka K, Hiroi T, Jutabha P, Iwata Y, Sugiura K, Owada T, Kurasawa K, Okayasu I, Ouchi M, Fujita T, Kanai Y, Endou H, Anzai N.

Allergy. 2019 Aug 12. doi: 10.1111/all.14019. [Epub ahead of print] No abstract available.

PMID:
31403710
3.

Natural American Spirit Brand Preference among Smokers with Mental Illness.

Epperson AE, Anzai NE, Prochaska JJ.

Tob Induc Dis. 2018 Sep;16. pii: 42. doi: 10.18332/tid/94456.

4.

Sodium-coupled monocarboxylate transporter 1 interacts with the RING finger- and PDZ domain-containing protein PDZRN3.

Otsuka Y, Furihata T, Nakagawa K, Ohno Y, Reien Y, Ouchi M, Wakashin H, Tsuruoka S, Anzai N.

J Physiol Sci. 2019 Jul;69(4):635-642. doi: 10.1007/s12576-019-00681-w. Epub 2019 May 16.

PMID:
31098988
5.

Identification of the multivalent PDZ protein PDZK1 as a binding partner of sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8) and SMCT2 (SLC5A12).

Srivastava S, Nakagawa K, He X, Kimura T, Fukutomi T, Miyauchi S, Sakurai H, Anzai N.

J Physiol Sci. 2019 Mar;69(2):399-408. doi: 10.1007/s12576-018-00658-1. Epub 2019 Jan 2.

PMID:
30604288
6.

Different Response Profiles of Gastrointestinal Cancer Cells to an L-Type Amino Acid Transporter Inhibitor, JPH203.

Muto Y, Furihata T, Kaneko M, Higuchi K, Okunushi K, Morio H, Reien Y, Uesato M, Matsubara H, Anzai N.

Anticancer Res. 2019 Jan;39(1):159-165. doi: 10.21873/anticanres.13092.

PMID:
30591453
7.

Synthesis of novel benzbromarone derivatives designed to avoid metabolic activation.

Ohe T, Umezawa R, Kitagawara Y, Yasuda D, Takahashi K, Nakamura S, Abe A, Sekine S, Ito K, Okunushi K, Morio H, Furihata T, Anzai N, Mashino T.

Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3708-3711. doi: 10.1016/j.bmcl.2018.10.023. Epub 2018 Oct 15.

PMID:
30389287
8.

Effects of uric acid on vascular endothelial function from bedside to bench.

Otani N, Toyoda S, Sakuma M, Hayashi K, Ouchi M, Fujita T, Anzai N, Tanaka A, Node K, Uemura N, Inoue T.

Hypertens Res. 2018 Nov;41(11):923-931. doi: 10.1038/s41440-018-0095-4. Epub 2018 Sep 5.

PMID:
30185927
9.

Differentiated HASTR/ci35 cells: A promising in vitro human astrocyte model for facilitating CNS drug development studies.

Kitamura K, Ito R, Umehara K, Morio H, Saito K, Suzuki S, Hashimoto M, Saito Y, Anzai N, Akita H, Chiba K, Furihata T.

J Pharmacol Sci. 2018 Aug;137(4):350-358. doi: 10.1016/j.jphs.2018.06.013. Epub 2018 Aug 9.

10.

Down-regulation of magnesium transporting molecule, claudin-16, as a possible cause of hypermagnesiuria with the development of tubulo-interstitial nephropathy.

Shimizu T, Takayanagi K, Iwashita T, Ikari A, Anzai N, Okazaki S, Hara H, Hatano M, Sano T, Ogawa T, Kanozawa K, Hasegawa H.

Magnes Res. 2018 Feb 1;31(1):11-23. doi: 10.1684/mrh.2018.0434.

PMID:
29991461
11.

Cancer-type organic anion transporting polypeptide 1B3 is a target for cancer suicide gene therapy using RNA trans-splicing technology.

Sun Y, Piñón Hofbauer J, Harada M, Wöss K, Koller U, Morio H, Stierschneider A, Kitamura K, Hashimoto M, Chiba K, Akita H, Anzai N, Reichelt J, Bauer JW, Guttmann-Gruber C, Furihata T.

Cancer Lett. 2018 Oct 1;433:107-116. doi: 10.1016/j.canlet.2018.06.032. Epub 2018 Jun 27.

PMID:
29960051
12.

The uricosuric effects of dihydropyridine calcium channel blockers in vivo using urate under-excretion animal models.

Hori T, Ouchi M, Otani N, Nohara M, Morita A, Otsuka Y, Jutabha P, Shibasaki I, Matsushita Y, Fujita T, Fukuda H, Anzai N.

J Pharmacol Sci. 2018 Apr;136(4):196-202. doi: 10.1016/j.jphs.2017.11.011. Epub 2018 Mar 8.

13.

Catalytic asymmetric synthesis of α-methyl-p-boronophenylalanine.

Harada S, Kajihara R, Muramoto R, Jutabha P, Anzai N, Nemoto T.

Bioorg Med Chem Lett. 2018 Jun 1;28(10):1915-1918. doi: 10.1016/j.bmcl.2018.03.075. Epub 2018 Mar 28.

PMID:
29655983
14.

Cancer-Type OATP1B3 mRNA in Extracellular Vesicles as a Promising Candidate for a Serum-Based Colorectal Cancer Biomarker.

Morio H, Sun Y, Harada M, Ide H, Shimozato O, Zhou X, Higashi K, Yuki R, Yamaguchi N, Hofbauer JP, Guttmann-Gruber C, Anzai N, Akita H, Chiba K, Furihata T.

Biol Pharm Bull. 2018;41(3):445-449. doi: 10.1248/bpb.b17-00743.

15.

Development of a New Conditionally Immortalized Human Liver Sinusoidal Endothelial Cells.

Zhu M, Koibuchi A, Ide H, Morio H, Shibuya M, Kamiichi A, Tsubota A, Anzai N, Akita H, Chiba K, Furihata T.

Biol Pharm Bull. 2018;41(3):440-444. doi: 10.1248/bpb.b17-00661.

16.

Organic anion transporter OAT3 enhances the glucosuric effect of the SGLT2 inhibitor empagliflozin.

Fu Y, Breljak D, Onishi A, Batz F, Patel R, Huang W, Song P, Freeman B, Mayoux E, Koepsell H, Anzai N, Nigam SK, Sabolic I, Vallon V.

Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F386-F394. doi: 10.1152/ajprenal.00503.2017. Epub 2018 Feb 7.

17.

Characterization of an L-Carnitine Transport System in Murine Photoreceptor Cell Line.

Ohno Y, Otsuka Y, Nohara M, Furihata T, Kuse Y, Itoh Y, Hara H, Anzai N.

Biol Pharm Bull. 2017;40(12):2110-2116. doi: 10.1248/bpb.b17-00461.

18.

Uric acid lowering in relation to HbA1c reductions with the SGLT2 inhibitor tofogliflozin.

Ouchi M, Oba K, Kaku K, Suganami H, Yoshida A, Fukunaka Y, Jutabha P, Morita A, Otani N, Hayashi K, Fujita T, Suzuki T, Yasutake M, Anzai N.

Diabetes Obes Metab. 2018 Apr;20(4):1061-1065. doi: 10.1111/dom.13170. Epub 2018 Jan 8.

19.

A New Conditionally Immortalized Human Fetal Brain Pericyte Cell Line: Establishment and Functional Characterization as a Promising Tool for Human Brain Pericyte Studies.

Umehara K, Sun Y, Hiura S, Hamada K, Itoh M, Kitamura K, Oshima M, Iwama A, Saito K, Anzai N, Chiba K, Akita H, Furihata T.

Mol Neurobiol. 2018 Jul;55(7):5993-6006. doi: 10.1007/s12035-017-0815-9. Epub 2017 Nov 11.

PMID:
29128907
20.

Electrophysiological analyses of transgenic mice overexpressing KCNJ8 with S422L mutation in cardiomyocytes.

Watanabe Y, Matsumoto A, Miki T, Seino S, Anzai N, Nakaya H.

J Pharmacol Sci. 2017 Sep;135(1):37-43. doi: 10.1016/j.jphs.2017.08.009. Epub 2017 Sep 6.

21.
22.

Reproducible insulin secretion from isolated rat pancreas preparations using an organ bath.

Morita A, Ouchi M, Terada M, Kon H, Kishimoto S, Satoh K, Otani N, Hayashi K, Fujita T, Inoue KI, Anzai N.

Exp Anim. 2018 Feb 9;67(1):15-22. doi: 10.1538/expanim.17-0059. Epub 2017 Jul 28.

23.

The RING finger- and PDZ domain-containing protein PDZRN3 controls localization of the Mg2+ regulator claudin-16 in renal tube epithelial cells.

Marunaka K, Furukawa C, Fujii N, Kimura T, Furuta T, Matsunaga T, Endo S, Hasegawa H, Anzai N, Yamazaki Y, Yamaguchi M, Ikari A.

J Biol Chem. 2017 Aug 4;292(31):13034-13044. doi: 10.1074/jbc.M117.779405. Epub 2017 Jun 16.

24.

Cancer-type OATP1B3 mRNA has the potential to become a detection and prognostic biomarker for human colorectal cancer.

Sun Y, Harada M, Shimozato O, Souda H, Takiguchi N, Nabeya Y, Kamijo T, Akita H, Anzai N, Chiba K, Furihata T.

Biomark Med. 2017 Aug;11(8):629-639. doi: 10.2217/bmm-2017-0098. Epub 2017 Jun 8.

PMID:
28592144
25.

Inhibition of l-type amino acid transporter 1 activity as a new therapeutic target for cholangiocarcinoma treatment.

Yothaisong S, Dokduang H, Anzai N, Hayashi K, Namwat N, Yongvanit P, Sangkhamanon S, Jutabha P, Endou H, Loilome W.

Tumour Biol. 2017 Mar;39(3):1010428317694545. doi: 10.1177/1010428317694545.

PMID:
28347255
26.

Novel therapeutic approaches targeting L-type amino acid transporters for cancer treatment.

Hayashi K, Anzai N.

World J Gastrointest Oncol. 2017 Jan 15;9(1):21-29. doi: 10.4251/wjgo.v9.i1.21. Review.

27.

Principal component analysis uncovers cytomegalovirus-associated NK cell activation in Ph+ leukemia patients treated with dasatinib.

Ishiyama K, Kitawaki T, Sugimoto N, Sozu T, Anzai N, Okada M, Nohgawa M, Hatanaka K, Arima N, Ishikawa T, Tabata S, Onaka T, Oka S, Nakabo Y, Amakawa R, Matsui M, Moriguchi T, Takaori-Kondo A, Kadowaki N.

Leukemia. 2017 Jan;31(1):268. doi: 10.1038/leu.2016.188. No abstract available.

PMID:
28050024
28.

Human organic anion transporter 2 is an entecavir, but not tenofovir, transporter.

Furihata T, Morio H, Zhu M, Suzuki Y, Ide H, Tsubota A, Fu Z, Anzai N, Chiba K.

Drug Metab Pharmacokinet. 2017 Feb;32(1):116-119. doi: 10.1016/j.dmpk.2016.09.004. Epub 2016 Sep 23.

PMID:
27916488
29.

Prior history of HLA-mismatched stem cell transplantation is a risk factor for graft failure in HLA-haploidentical transplantation.

Sugita J, Miyamoto T, Kawashima N, Hatsumi N, Anzai N, Kaneko H, Nara M, Minauchi K, Harada M, Teshima T.

Bone Marrow Transplant. 2017 Feb;52(2):323-325. doi: 10.1038/bmt.2016.278. Epub 2016 Nov 7. No abstract available.

PMID:
27819686
30.

Matrix-assisted laser desorption/ionization imaging mass spectrometry reveals changes of phospholipid distribution in induced pluripotent stem cell colony differentiation.

Shimizu Y, Satou M, Hayashi K, Nakamura Y, Fujimaki M, Horibata Y, Ando H, Watanabe T, Shiobara T, Chibana K, Takemasa A, Sugimoto H, Anzai N, Ishii Y.

Anal Bioanal Chem. 2017 Feb;409(4):1007-1016. doi: 10.1007/s00216-016-0015-x. Epub 2016 Nov 4.

PMID:
27815610
31.

A kidney injury molecule-1 (Kim-1) gene reporter in a mouse artificial chromosome: the responsiveness to cisplatin toxicity in immortalized mouse kidney S3 cells.

Kokura K, Kuromi Y, Endo T, Anzai N, Kazuki Y, Oshimura M, Ohbayashi T.

J Gene Med. 2016 Oct;18(10):273-281. doi: 10.1002/jgm.2925.

32.

Correlates of nicotine withdrawal severity in smokers during a smoke-free psychiatric hospitalization.

Soyster P, Anzai NE, Fromont SC, Prochaska JJ.

Prev Med. 2016 Nov;92:176-182. doi: 10.1016/j.ypmed.2016.01.026. Epub 2016 Feb 15.

33.

Associations of fibroblast growth factor 23 with urate metabolism in patients with chronic kidney disease.

Sakoh T, Nakayama M, Tsuchihashi T, Yoshitomi R, Tanaka S, Katafuchi E, Fukui A, Shikuwa Y, Anzai N, Kitazono T, Tsuruya K.

Metabolism. 2016 Oct;65(10):1498-507. doi: 10.1016/j.metabol.2016.07.005. Epub 2016 Jul 19.

PMID:
27621185
34.

Roles of organic anion transporters (OATs) in renal proximal tubules and their localization.

Otani N, Ouchi M, Hayashi K, Jutabha P, Anzai N.

Anat Sci Int. 2017 Mar;92(2):200-206. doi: 10.1007/s12565-016-0369-3. Epub 2016 Sep 10. Review.

PMID:
27614971
35.

LAT1 acts as a crucial transporter of amino acids in human thymic carcinoma cells.

Hayashi K, Jutabha P, Maeda S, Supak Y, Ouchi M, Endou H, Fujita T, Chida M, Anzai N.

J Pharmacol Sci. 2016 Nov;132(3):201-204. doi: 10.1016/j.jphs.2016.07.006. Epub 2016 Jul 27.

36.

Principal component analysis uncovers cytomegalovirus-associated NK cell activation in Ph+ leukemia patients treated with dasatinib.

Ishiyama K, Kitawaki T, Sugimoto N, Sozu T, Anzai N, Okada M, Nohgawa M, Hatanaka K, Arima N, Ishikawa T, Tabata S, Onaka T, Oka S, Nakabo Y, Amakawa R, Matsui M, Moriguchi T, Takaori-Kondo A, Kadowaki N.

Leukemia. 2017 Jan;31(1):203-212. doi: 10.1038/leu.2016.174. Epub 2016 Jun 14. Erratum in: Leukemia. 2017 Jan;31(1):268. Ishiyama, K-I [corrected to Ishiyama, K].

PMID:
27349810
37.

Likelihood of Unemployed Smokers vs Nonsmokers Attaining Reemployment in a One-Year Observational Study.

Prochaska JJ, Michalek AK, Brown-Johnson C, Daza EJ, Baiocchi M, Anzai N, Rogers A, Grigg M, Chieng A.

JAMA Intern Med. 2016 May 1;176(5):662-70. doi: 10.1001/jamainternmed.2016.0772.

38.

Distribution of organic anion transporters NaDC3 and OAT1-3 along the human nephron.

Breljak D, Ljubojević M, Hagos Y, Micek V, Balen Eror D, Vrhovac Madunić I, Brzica H, Karaica D, Radović N, Kraus O, Anzai N, Koepsell H, Burckhardt G, Burckhardt BC, Sabolić I.

Am J Physiol Renal Physiol. 2016 Jul 1;311(1):F227-38. doi: 10.1152/ajprenal.00113.2016. Epub 2016 Apr 6.

39.

HOXB9 acts as a negative regulator of activated human T cells in response to amino acid deficiency.

Hayashi K, Ouchi M, Endou H, Anzai N.

Immunol Cell Biol. 2016 Jul;94(6):612-7. doi: 10.1038/icb.2016.13. Epub 2016 Mar 1.

PMID:
26926958
40.

Effects of Uric Acid on the NO Production of HUVECs and its Restoration by Urate Lowering Agents.

Mishima M, Hamada T, Maharani N, Ikeda N, Onohara T, Notsu T, Ninomiya H, Miyazaki S, Mizuta E, Sugihara S, Kato M, Ogino K, Kuwabara M, Hirota Y, Yoshida A, Otani N, Anzai N, Hisatome I.

Drug Res (Stuttg). 2016 May;66(5):270-4. doi: 10.1055/s-0035-1569405. Epub 2016 Feb 24.

PMID:
26909689
41.

[The Report of the Survey to the Members of the Society about the Functional Dissociation of the Psychiatric Hospital beds].

Matsubara S, Anzai N, Ota J, Ohmori T, Kodaka A, Sato S, Sano I, Hatou K, Mikuni M, Yamanouchi Y, Yoshizumi A, Watanabe Y.

Seishin Shinkeigaku Zasshi. 2016;118(9):680-687. Japanese.

PMID:
30620860
42.

Increase in L-type amino acid transporter 1 expression during cholangiocarcinogenesis caused by liver fluke infection and its prognostic significance.

Yothaisong S, Namwat N, Yongvanit P, Khuntikeo N, Puapairoj A, Jutabha P, Anzai N, Tassaneeyakul W, Tangsucharit P, Loilome W.

Parasitol Int. 2017 Aug;66(4):471-478. doi: 10.1016/j.parint.2015.11.011. Epub 2015 Nov 30.

PMID:
26657242
43.
44.

Interaction of green tea catechins with renal organic cation transporter 2.

Jaiyen C, Jutabha P, Anzai N, Lungkaphin A, Soodvilai S, Srimaroeng C.

Xenobiotica. 2016 Jul;46(7):641-650. doi: 10.3109/00498254.2015.1107785. Epub 2015 Nov 17.

PMID:
26576923
45.

Organic Anion Transporter 5 (Oat5) Urinary Excretion Is a Specific Biomarker of Kidney Injury: Evaluation of Urinary Excretion of Exosomal Oat5 after N-Acetylcysteine Prevention of Cisplatin Induced Nephrotoxicity.

Bulacio RP, Anzai N, Ouchi M, Torres AM.

Chem Res Toxicol. 2015 Aug 17;28(8):1595-602. doi: 10.1021/acs.chemrestox.5b00176. Epub 2015 Aug 7.

PMID:
26230185
46.

[Disturbance of uric acid metabolism].

Ouchi M, Otani N, Anzai N.

Nihon Jinzo Gakkai Shi. 2015;57(4):766-73. Japanese. No abstract available.

PMID:
26126334
47.

Symptom severity and readiness to quit among hospitalized smokers with mental illness.

Anzai N, Young-Wolff KC, Prochaska JJ.

Psychiatr Serv. 2015 Apr 1;66(4):443-4. doi: 10.1176/appi.ps.201400181. No abstract available.

48.

Cord Blood Transplantation for Multiple Myeloma: A Study from the Multiple Myeloma Working Group of the Japan Society for Hematopoietic Cell Transplantation.

Kawamura K, Takamatsu H, Ikeda T, Komatsu T, Aotsuka N, Amano I, Yamamoto G, Watanabe K, Ohno Y, Matsue K, Kouzai Y, Tsukada N, Ishiyama K, Anzai N, Kato K, Suzuki R, Sunami K, Kanda Y.

Biol Blood Marrow Transplant. 2015 Jul;21(7):1291-8. doi: 10.1016/j.bbmt.2015.02.015. Epub 2015 Feb 21.

49.

Association between pulse wave velocity and a marker of renal tubular damage (N-acetyl-β-D-glucosaminidase) in patients without diabetes.

Ouchi M, Oba K, Saigusa T, Watanabe K, Ohara M, Matsumura N, Suzuki T, Anzai N, Tsuruoka S, Yasutake M.

J Clin Hypertens (Greenwich). 2015 Apr;17(4):290-7. doi: 10.1111/jch.12492. Epub 2015 Feb 9.

50.

Role of LAT1 in the promotion of amino acid incorporation in activated T cells.

Hayashi K, Anzai N.

Crit Rev Immunol. 2014;34(6):467-79. Review.

PMID:
25597310

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