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Novel therapeutic strategies for spinal osteosarcomas.

Anwar MA, El-Baba C, Elnaggar MH, Elkholy YO, Mottawea M, Johar D, Al Shehabi TS, Kobeissy F, Moussalem C, Massaad E, Omeis I, Darwiche N, Eid AH.

Semin Cancer Biol. 2019 May 29. pii: S1044-579X(18)30156-1. doi: 10.1016/j.semcancer.2019.05.018. [Epub ahead of print] Review.


Predictive Factors and Rates of Fusion in Minimally Invasive Transforaminal Lumbar Interbody Fusion Utilizing rhBMP-2 or Mesenchymal Stem Cells.

Overley SC, McAnany SJ, Anwar MA, Merrill RK, Lovy A, Guzman JZ, Zhadanov S, Doshi A, Rothenberg E, Vaishnav A, Gang C, Qureshi SA.

Int J Spine Surg. 2019 Feb 22;13(1):46-52. doi: 10.14444/6007. eCollection 2019 Jan.


Bioactivity evaluation and HPLC UV-VIS based quantification of antioxidant secondary metabolites from extract and fractions of Bistorta amplexicaulis rhizome.

Tabassam S, Anwar MA, Gulfraz M, Arshad M, Sabitaliyevich UY, Nurmurzayevich SB, Ahmad MS.

Cell Mol Biol (Noisy-le-grand). 2019 Jan 31;65(1):19-26.


Multiplexed LC-ESI-MRM-MS-based Assay for Identification of Coronary Artery Disease Biomarkers in Human Plasma.

Anwar MA, Dai DL, Wilson-McManus J, Smith D, Francis GA, Borchers CH, McManus BM, Hill JS, Cohen Freue GV.

Proteomics Clin Appl. 2019 Jan 11:e1700111. doi: 10.1002/prca.201700111. [Epub ahead of print]


Molecular Interactions Between Innate and Adaptive Immune Cells in Chronic Lymphocytic Leukemia and Their Therapeutic Implications.

Haseeb M, Anwar MA, Choi S.

Front Immunol. 2018 Nov 26;9:2720. doi: 10.3389/fimmu.2018.02720. eCollection 2018. Review.


Effectiveness of fascial closure technique following percutaneous endovascular aneurysm repair.

Majid K, Anwar MA, Shepherd A, Malina M, Hussain T.

Ann R Coll Surg Engl. 2019 Jan;101(1):14-16. doi: 10.1308/rcsann.2018.0200. Epub 2018 Nov 28.


Recent clinical trends in Toll-like receptor targeting therapeutics.

Anwar MA, Shah M, Kim J, Choi S.

Med Res Rev. 2019 May;39(3):1053-1090. doi: 10.1002/med.21553. Epub 2018 Nov 18. Review.


Rhus coriaria L. (Sumac) Evokes Endothelium-Dependent Vasorelaxation of Rat Aorta: Involvement of the cAMP and cGMP Pathways.

Anwar MA, Samaha AA, Baydoun S, Iratni R, Eid AH.

Front Pharmacol. 2018 Jun 28;9:688. doi: 10.3389/fphar.2018.00688. eCollection 2018.


Fate of the tributaries of sapheno femoral junction following endovenous thermal ablation of incompetent axial vein - A review article.

Anwar MA, Idrees M, Aswini M, Theivacumar NS.

Phlebology. 2019 Apr;34(3):151-155. doi: 10.1177/0268355518783635. Epub 2018 Jun 27.


Comparing the Incidence of Index Level Fusion Following Minimally Invasive Versus Open Lumbar Microdiscectomy.

McAnany SJ, Overley SC, Anwar MA, Cutler HS, Guzman JZ, Kim JS, Merrill RK, Cho SK, Hecht AC, Qureshi SA.

Global Spine J. 2018 Feb;8(1):11-16. doi: 10.1177/2192568217718818. Epub 2017 Sep 22.


Basic understanding and therapeutic approaches to target toll-like receptors in cancerous microenvironment and metastasis.

Khajeh Alizadeh Attar M, Anwar MA, Eskian M, Keshavarz-Fathi M, Choi S, Rezaei N.

Med Res Rev. 2018 Sep;38(5):1469-1484. doi: 10.1002/med.21480. Epub 2017 Dec 28. Review.


Evaluation of Sox2 binding affinities for distinct DNA patterns using steered molecular dynamics simulation.

Yesudhas D, Anwar MA, Panneerselvam S, Kim HK, Choi S.

FEBS Open Bio. 2017 Oct 9;7(11):1750-1767. doi: 10.1002/2211-5463.12316. eCollection 2017 Nov.


Proteins Recognizing DNA: Structural Uniqueness and Versatility of DNA-Binding Domains in Stem Cell Transcription Factors.

Yesudhas D, Batool M, Anwar MA, Panneerselvam S, Choi S.

Genes (Basel). 2017 Aug 1;8(8). pii: E192. doi: 10.3390/genes8080192. Review.


A comprehensive characterisation of the metabolic profile of varicose veins; implications in elaborating plausible cellular pathways for disease pathogenesis.

Anwar MA, Adesina-Georgiadis KN, Spagou K, Vorkas PA, Li JV, Shalhoub J, Holmes E, Davies AH.

Sci Rep. 2017 Jun 7;7(1):2989. doi: 10.1038/s41598-017-02529-y.


Salvia fruticosa Induces Vasorelaxation In Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway.

Anwar MA, Samaha AA, Ballan S, Saleh AI, Iratni R, Eid AH.

Sci Rep. 2017 Apr 6;7(1):686. doi: 10.1038/s41598-017-00790-9.


TLR4/MD2 specific peptides stalled in vivo LPS-induced immune exacerbation.

Park S, Shin HJ, Shah M, Cho HY, Anwar MA, Achek A, Kwon HK, Lee B, Yoo TH, Choi S.

Biomaterials. 2017 May;126:49-60. doi: 10.1016/j.biomaterials.2017.02.023. Epub 2017 Feb 20.


A structural insight into the negative effects of opioids in analgesia by modulating the TLR4 signaling: An in silico approach.

Shah M, Anwar MA, Yesudhas D, Krishnan J, Choi S.

Sci Rep. 2016 Dec 16;6:39271. doi: 10.1038/srep39271.


Electrophysiological identification of nonrecurrent laryngeal nerves.

Kandil E, Anwar MA, Bamford J, Aslam R, Randolph GW.

Laryngoscope. 2017 Sep;127(9):2189-2193. doi: 10.1002/lary.26407. Epub 2016 Nov 15.


Etoposide induced cytotoxicity mediated by ROS and ERK in human kidney proximal tubule cells.

Shin HJ, Kwon HK, Lee JH, Anwar MA, Choi S.

Sci Rep. 2016 Sep 26;6:34064. doi: 10.1038/srep34064.


Toll-like receptors targeting technology for the treatment of lymphoma.

Batool M, Anwar MA, Choi S.

Expert Opin Drug Discov. 2016 Nov;11(11):1047-1059. Epub 2016 Sep 19. Review.


Distribution and clinical significance of hepatitis B virus genotypes in Pakistan.

Mahmood M, Anwar MA, Khanum A, Zaman N, Raza A.

BMC Gastroenterol. 2016 Aug 26;16:104. doi: 10.1186/s12876-016-0513-5.


Prolonged Mechanical Circumferential Stretch Induces Metabolic Changes in Rat Inferior Vena Cava.

Anwar MA, Vorkas PA, Li J, Adesina-Georgiadis KN, Reslan OM, Raffetto JD, Want EJ, Khalil RA, Holmes E, Davies AH.

Eur J Vasc Endovasc Surg. 2016 Oct;52(4):544-552. doi: 10.1016/j.ejvs.2016.07.002. Epub 2016 Aug 11.


The significance of enlarged cervical lymph nodes in diagnosing thyroid cancer.

Mohamed HE, Mohamed SE, Anwar MA, Al-Qurayshi Z, Sholl A, Thethi T, Khan A, Aslam R, Kandil E.

J Cancer Res Ther. 2016 Apr-Jun;12(2):1006-9. doi: 10.4103/0973-1482.171360.


PCR-Based Molecular Diagnosis of Hepatitis Virus (HBV and HDV) in HCV Infected Patients and Their Biochemical Study.

Riaz MN, Faheem M, Anwar MA, Raheel U, Badshah Y, Akhtar H, Tamanna K, Tahir M, Sadaf Zaidi NU, Qadri I.

J Pathog. 2016;2016:3219793. doi: 10.1155/2016/3219793. Epub 2016 Jun 6.


Immunohistochemistry as a reliable method for detection of BRAF-V600E mutation in melanoma: a systematic review and meta-analysis of current published literature.

Anwar MA, Murad F, Dawson E, Abd Elmageed ZY, Tsumagari K, Kandil E.

J Surg Res. 2016 Jun 15;203(2):407-15. doi: 10.1016/j.jss.2016.04.029. Epub 2016 Apr 23. Review.


Inflammogenesis of Secondary Spinal Cord Injury.

Anwar MA, Al Shehabi TS, Eid AH.

Front Cell Neurosci. 2016 Apr 13;10:98. doi: 10.3389/fncel.2016.00098. eCollection 2016. Review.


Anti-Hypertensive Herbs and Their Mechanisms of Action: Part II.

Anwar MA, Al Disi SS, Eid AH.

Front Pharmacol. 2016 Mar 8;7:50. doi: 10.3389/fphar.2016.00050. eCollection 2016. Review.


Glucocorticoid-induced fetal origins of adult hypertension: Association with epigenetic events.

Anwar MA, Saleh AI, Al Olabi R, Al Shehabi TS, Eid AH.

Vascul Pharmacol. 2016 Jul;82:41-50. doi: 10.1016/j.vph.2016.02.002. Epub 2016 Feb 20. Review.


Advances in Antiviral Therapies Targeting Toll-like Receptors.

Shah M, Anwar MA, Kim JH, Choi S.

Expert Opin Investig Drugs. 2016;25(4):437-53. doi: 10.1517/13543784.2016.1154040. Epub 2016 Feb 29. Review.


Anti-hypertensive Herbs and their Mechanisms of Action: Part I.

Al Disi SS, Anwar MA, Eid AH.

Front Pharmacol. 2016 Jan 19;6:323. doi: 10.3389/fphar.2015.00323. eCollection 2015. Review.


Structural Mechanism behind Distinct Efficiency of Oct4/Sox2 Proteins in Differentially Spaced DNA Complexes.

Yesudhas D, Anwar MA, Panneerselvam S, Durai P, Shah M, Choi S.

PLoS One. 2016 Jan 20;11(1):e0147240. doi: 10.1371/journal.pone.0147240. eCollection 2016.


The triumph of chemically enhanced cellular reprogramming: a patent review.

Anwar MA, Kim S, Choi S.

Expert Opin Ther Pat. 2016;26(2):265-80. doi: 10.1517/13543776.2016.1118058. Epub 2015 Dec 4. Review.


Optimization of metabolite extraction of human vein tissue for ultra performance liquid chromatography-mass spectrometry and nuclear magnetic resonance-based untargeted metabolic profiling.

Anwar MA, Vorkas PA, Li JV, Shalhoub J, Want EJ, Davies AH, Holmes E.

Analyst. 2015 Nov 21;140(22):7586-97. doi: 10.1039/c5an01041a.


Activating transcription factor 3 represses inflammatory responses by binding to the p65 subunit of NF-κB.

Kwon JW, Kwon HK, Shin HJ, Choi YM, Anwar MA, Choi S.

Sci Rep. 2015 Sep 28;5:14470. doi: 10.1038/srep14470.


In silico mechanistic analysis of IRF3 inactivation and high-risk HPV E6 species-dependent drug response.

Shah M, Anwar MA, Park S, Jafri SS, Choi S.

Sci Rep. 2015 Aug 20;5:13446. doi: 10.1038/srep13446.


A Combined Molecular Docking/Dynamics Approach to Probe the Binding Mode of Cancer Drugs with Cytochrome P450 3A4.

Panneerselvam S, Yesudhas D, Durai P, Anwar MA, Gosu V, Choi S.

Molecules. 2015 Aug 14;20(8):14915-35. doi: 10.3390/molecules200814915.


Mechanism of Cisplatin-Induced Cytotoxicity Is Correlated to Impaired Metabolism Due to Mitochondrial ROS Generation.

Choi YM, Kim HK, Shim W, Anwar MA, Kwon JW, Kwon HK, Kim HJ, Jeong H, Kim HM, Hwang D, Kim HS, Choi S.

PLoS One. 2015 Aug 6;10(8):e0135083. doi: 10.1371/journal.pone.0135083. eCollection 2015.


Reverse phase high performance liquid chromatographic method development based on ultravioletvisible detector for the analysis of 1-hydroxypyrene (PAH biomarker) in human urine.

Kamal A, Gulfraz M, Anwar MA, Malik RN.

Int J Occup Med Environ Health. 2015;28(2):399-403. doi: 10.13075/ijomeh.1896.00325.


CKD-MBD spectrum at the time of initiation of hemodialysis in Pakistani chronic kidney disease patients.

Hafeez E, Raza H, Khan RU, Anwar MA, Hussain T, Beg MA.

Saudi J Kidney Dis Transpl. 2015 Jul-Aug;26(4):823-6. doi: 10.4103/1319-2442.160227.


Decision analytic modeling in spinal surgery: a methodologic overview with review of current published literature.

McAnany SJ, Anwar MA, Qureshi SA.

Spine J. 2015 Oct 1;15(10):2254-70. doi: 10.1016/j.spinee.2015.06.045. Epub 2015 Jun 23. Review.


Fatal human eosinophilic meningo-encephalitis caused by CNS co-infection with Halicephalobus gingivalis and West Nile virus.

Anwar MA, Gokozan HN, Ball MK, Otero J, McGwire BS.

Parasitol Int. 2015 Oct;64(5):417-20. doi: 10.1016/j.parint.2015.06.001. Epub 2015 Jun 5.


Pleural Fibroma; A meandering path to surgical removal.

Hassan S, Husain SS, Anwar MA, Saeed S.

Pak J Med Sci. 2015 Jan-Feb;31(1):236-8. doi: 10.12669/pjms.311.5517.


Prevalence and gene frequency of color vision impairments among children of six populations from North Indian region.

Fareed M, Anwar MA, Afzal M.

Genes Dis. 2015 Feb 25;2(2):211-218. doi: 10.1016/j.gendis.2015.02.006. eCollection 2015 Jun.


Untargeted UPLC-MS profiling pipeline to expand tissue metabolome coverage: application to cardiovascular disease.

Vorkas PA, Isaac G, Anwar MA, Davies AH, Want EJ, Nicholson JK, Holmes E.

Anal Chem. 2015 Apr 21;87(8):4184-93. doi: 10.1021/ac503775m. Epub 2015 Apr 8.


Insights into the species-specific TLR4 signaling mechanism in response to Rhodobacter sphaeroides lipid A detection.

Anwar MA, Panneerselvam S, Shah M, Choi S.

Sci Rep. 2015 Jan 7;5:7657. doi: 10.1038/srep07657.


Phylogenetic characterization and novelty of organic sulphur metabolizing genes of Rhodococcus spp. (Eu-32).

Akhtar N, Ghauri MA, Anwar MA, Heaphy S.

Biotechnol Lett. 2015 Apr;37(4):837-47. doi: 10.1007/s10529-014-1736-6. Epub 2014 Dec 10.


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