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Items: 1 to 50 of 124

1.

Cancer Incidence in C3H Mice Protected from Lethal Total-Body Radiation after Amifostine.

Cook JA, Naz S, Anver MR, Sowers AL, Fabre K, Krishna MC, Mitchell JB.

Radiat Res. 2018 May;189(5):490-496. doi: 10.1667/RR14987.1. Epub 2018 Mar 12.

2.

Interleukin-27 Is a Potential Rescue Therapy for Acute Severe Colitis Through Interleukin-10-Dependent, T-Cell-Independent Attenuation of Colonic Mucosal Innate Immune Responses.

McLean MH, Andrews C, Hanson ML, Baseler WA, Anver MR, Senkevitch E, Staniszewska AK, Smith C, Davies LC, Hixon J, Li W, Shen W, Steidler L, Durum SK.

Inflamm Bowel Dis. 2017 Nov;23(11):1983-1995. doi: 10.1097/MIB.0000000000001274.

3.

Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis.

Yang Y, Yang HH, Hu Y, Watson PH, Liu H, Geiger TR, Anver MR, Haines DC, Martin P, Green JE, Lee MP, Hunter KW, Wakefield LM.

Oncotarget. 2017 May 9;8(19):30621-30643. doi: 10.18632/oncotarget.15695.

4.

Adaptation of Laser Microdissection Technique for the Study of a Spontaneous Metastatic Mammary Carcinoma Mouse Model by NanoString Technologies.

Castro NP, Merchant AS, Saylor KL, Anver MR, Salomon DS, Golubeva YG.

PLoS One. 2016 Apr 14;11(4):e0153270. doi: 10.1371/journal.pone.0153270. eCollection 2016.

5.

Mass Spectrometry-Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer.

Cook JA, Chandramouli GV, Anver MR, Sowers AL, Thetford A, Krausz KW, Gonzalez FJ, Mitchell JB, Patterson AD.

Cancer Res. 2016 Mar 15;76(6):1569-77. doi: 10.1158/0008-5472.CAN-15-2416. Epub 2016 Feb 15.

6.

IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice.

Hodge DL, Berthet C, Coppola V, Kastenmüller W, Buschman MD, Schaughency PM, Shirota H, Scarzello AJ, Subleski JJ, Anver MR, Ortaldo JR, Lin F, Reynolds DA, Sanford ME, Kaldis P, Tessarollo L, Klinman DM, Young HA.

J Autoimmun. 2014 Sep;53:33-45. doi: 10.1016/j.jaut.2014.02.003. Epub 2014 Feb 28.

7.

Sporadic naturally occurring melanoma in dogs as a preclinical model for human melanoma.

Simpson RM, Bastian BC, Michael HT, Webster JD, Prasad ML, Conway CM, Prieto VM, Gary JM, Goldschmidt MH, Esplin DG, Smedley RC, Piris A, Meuten DJ, Kiupel M, Lee CC, Ward JM, Dwyer JE, Davis BJ, Anver MR, Molinolo AA, Hoover SB, Rodriguez-Canales J, Hewitt SM.

Pigment Cell Melanoma Res. 2014 Jan;27(1):37-47. doi: 10.1111/pcmr.12185. Epub 2013 Nov 21.

8.

Oral delivery of IL-27 recombinant bacteria attenuates immune colitis in mice.

Hanson ML, Hixon JA, Li W, Felber BK, Anver MR, Stewart CA, Janelsins BM, Datta SK, Shen W, McLean MH, Durum SK.

Gastroenterology. 2014 Jan;146(1):210-221.e13. doi: 10.1053/j.gastro.2013.09.060. Epub 2013 Oct 9.

9.

Insulin-dependent diabetes induced by pancreatic beta cell expression of IL-15 and IL-15Rα.

Chen J, Feigenbaum L, Awasthi P, Butcher DO, Anver MR, Golubeva YG, Bamford R, Zhang X, St Claire MB, Thomas CJ, Discepolo V, Jabri B, Waldmann TA.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13534-9. doi: 10.1073/pnas.1312911110. Epub 2013 Jul 31.

10.

Characterization of NADPH oxidase 5 expression in human tumors and tumor cell lines with a novel mouse monoclonal antibody.

Antony S, Wu Y, Hewitt SM, Anver MR, Butcher D, Jiang G, Meitzler JL, Liu H, Juhasz A, Lu J, Roy KK, Doroshow JH.

Free Radic Biol Med. 2013 Dec;65:497-508. doi: 10.1016/j.freeradbiomed.2013.07.005. Epub 2013 Jul 11.

11.

Selenium and selenoprotein deficiencies induce widespread pyogranuloma formation in mice, while high levels of dietary selenium decrease liver tumor size driven by TGFα.

Moustafa ME, Carlson BA, Anver MR, Bobe G, Zhong N, Ward JM, Perella CM, Hoffmann VJ, Rogers K, Combs GF Jr, Schweizer U, Merlino G, Gladyshev VN, Hatfield DL.

PLoS One. 2013;8(2):e57389. doi: 10.1371/journal.pone.0057389. Epub 2013 Feb 27.

12.

Restricted cell surface expression of receptor tyrosine kinase ROR1 in pediatric B-lineage acute lymphoblastic leukemia suggests targetability with therapeutic monoclonal antibodies.

Dave H, Anver MR, Butcher DO, Brown P, Khan J, Wayne AS, Baskar S, Rader C.

PLoS One. 2012;7(12):e52655. doi: 10.1371/journal.pone.0052655. Epub 2012 Dec 20.

13.

Interleukin-6 is essential for primary resistance to Francisella tularensis live vaccine strain infection.

Kurtz SL, Foreman O, Bosio CM, Anver MR, Elkins KL.

Infect Immun. 2013 Feb;81(2):585-97. doi: 10.1128/IAI.01249-12. Epub 2012 Dec 10.

14.

The antioxidant tempol reduces carcinogenesis and enhances survival in mice when administered after nonlethal total body radiation.

Mitchell JB, Anver MR, Sowers AL, Rosenberg PS, Figueroa M, Thetford A, Krishna MC, Albert PS, Cook JA.

Cancer Res. 2012 Sep 15;72(18):4846-55. doi: 10.1158/0008-5472.CAN-12-1879. Epub 2012 Jul 17.

15.

Melanoma induction by ultraviolet A but not ultraviolet B radiation requires melanin pigment.

Noonan FP, Zaidi MR, Wolnicka-Glubisz A, Anver MR, Bahn J, Wielgus A, Cadet J, Douki T, Mouret S, Tucker MA, Popratiloff A, Merlino G, De Fabo EC.

Nat Commun. 2012 Jun 6;3:884. doi: 10.1038/ncomms1893.

16.

Sunscreen prevention of melanoma in man and mouse.

Klug HL, Tooze JA, Graff-Cherry C, Anver MR, Noonan FP, Fears TR, Tucker MA, De Fabo EC, Merlino G.

Pigment Cell Melanoma Res. 2010 Dec;23(6):835-7. doi: 10.1111/j.1755-148X.2010.00756.x. Epub 2010 Aug 20. No abstract available.

17.

Visualization and identification of IL-7 producing cells in reporter mice.

Mazzucchelli RI, Warming S, Lawrence SM, Ishii M, Abshari M, Washington AV, Feigenbaum L, Warner AC, Sims DJ, Li WQ, Hixon JA, Gray DH, Rich BE, Morrow M, Anver MR, Cherry J, Naf D, Sternberg LR, McVicar DW, Farr AG, Germain RN, Rogers K, Jenkins NA, Copeland NG, Durum SK.

PLoS One. 2009 Nov 10;4(11):e7637. doi: 10.1371/journal.pone.0007637.

18.

GalNAcalpha1-3Gal, a new prognostic marker for cervical cancer.

Li Q, Anver MR, Li Z, Butcher DO, Gildersleeve JC.

Int J Cancer. 2010 Jan 15;126(2):459-68. doi: 10.1002/ijc.24716.

19.

Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition.

Rapisarda A, Hollingshead M, Uranchimeg B, Bonomi CA, Borgel SD, Carter JP, Gehrs B, Raffeld M, Kinders RJ, Parchment R, Anver MR, Shoemaker RH, Melillo G.

Mol Cancer Ther. 2009 Jul;8(7):1867-77. doi: 10.1158/1535-7163.MCT-09-0274. Epub 2009 Jul 7.

20.

Resolving conflicting data on expression of the Tn antigen and implications for clinical trials with cancer vaccines.

Li Q, Anver MR, Butcher DO, Gildersleeve JC.

Mol Cancer Ther. 2009 Apr;8(4):971-9. doi: 10.1158/1535-7163.MCT-08-0934.

21.

Bone marrow deficient in IFN-{gamma} signaling selectively reverses GVHD-associated immunosuppression and enhances a tumor-specific GVT effect.

Capitini CM, Herby S, Milliron M, Anver MR, Mackall CL, Fry TJ.

Blood. 2009 May 14;113(20):5002-9. doi: 10.1182/blood-2008-11-187385. Epub 2009 Mar 3.

22.

Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness.

Jin C, Yang YA, Anver MR, Morris N, Wang X, Zhang YE.

Cancer Res. 2009 Feb 1;69(3):735-40. doi: 10.1158/0008-5472.CAN-08-1463. Epub 2009 Jan 20.

23.

Marked liver tumorigenesis by Helicobacter hepaticus requires perinatal exposure.

Diwan BA, Sipowicz M, Logsdon D, Gorelick P, Anver MR, Kasprzak KS, Anderson LM.

Environ Health Perspect. 2008 Oct;116(10):1352-6. doi: 10.1289/ehp.11493. Epub 2008 Jun 13.

24.

Strain-specific spontaneous and NNK-mediated tumorigenesis in Pten+/- mice.

Hollander MC, Balogh AR, Liwanag J, Han W, Linnoila RI, Anver MR, Dennis PA.

Neoplasia. 2008 Aug;10(8):866-72.

25.

Identification of VEGF-regulated genes associated with increased lung metastatic potential: functional involvement of tenascin-C in tumor growth and lung metastasis.

Calvo A, Catena R, Noble MS, Carbott D, Gil-Bazo I, Gonzalez-Moreno O, Huh JI, Sharp R, Qiu TH, Anver MR, Merlino G, Dickson RB, Johnson MD, Green JE.

Oncogene. 2008 Sep 11;27(40):5373-84. doi: 10.1038/onc.2008.155. Epub 2008 May 26.

26.

An anti-transforming growth factor beta antibody suppresses metastasis via cooperative effects on multiple cell compartments.

Nam JS, Terabe M, Mamura M, Kang MJ, Chae H, Stuelten C, Kohn E, Tang B, Sabzevari H, Anver MR, Lawrence S, Danielpour D, Lonning S, Berzofsky JA, Wakefield LM.

Cancer Res. 2008 May 15;68(10):3835-43. doi: 10.1158/0008-5472.CAN-08-0215.

27.

Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1.

Wright MH, Robles AI, Herschkowitz JI, Hollingshead MG, Anver MR, Perou CM, Varticovski L.

Mol Cancer. 2008 Apr 7;7:29. doi: 10.1186/1476-4598-7-29.

28.

Expression of POTE protein in human testis detected by novel monoclonal antibodies.

Ise T, Das S, Nagata S, Maeda H, Lee Y, Onda M, Anver MR, Bera TK, Pastan I.

Biochem Biophys Res Commun. 2008 Jan 25;365(4):603-8. Epub 2007 Nov 9.

29.

Transforming growth factor-beta can suppress tumorigenesis through effects on the putative cancer stem or early progenitor cell and committed progeny in a breast cancer xenograft model.

Tang B, Yoo N, Vu M, Mamura M, Nam JS, Ooshima A, Du Z, Desprez PY, Anver MR, Michalowska AM, Shih J, Parks WT, Wakefield LM.

Cancer Res. 2007 Sep 15;67(18):8643-52.

30.

Accelerated preclinical testing using transplanted tumors from genetically engineered mouse breast cancer models.

Varticovski L, Hollingshead MG, Robles AI, Wu X, Cherry J, Munroe DJ, Lukes L, Anver MR, Carter JP, Borgel SD, Stotler H, Bonomi CA, Nunez NP, Hursting SD, Qiao W, Deng CX, Green JE, Hunter KW, Merlino G, Steeg PS, Wakefield LM, Barrett JC.

Clin Cancer Res. 2007 Apr 1;13(7):2168-77.

31.

Cellular and tissue distribution of intravenously administered agalsidase alfa.

Murray GJ, Anver MR, Kennedy MA, Quirk JM, Schiffmann R.

Mol Genet Metab. 2007 Mar;90(3):307-12. Epub 2006 Dec 22.

32.

Precancer in mice: animal models used to understand, prevent, and treat human precancers.

Cardiff RD, Anver MR, Boivin GP, Bosenberg MW, Maronpot RR, Molinolo AA, Nikitin AY, Rehg JE, Thomas GV, Russell RG, Ward JM.

Toxicol Pathol. 2006;34(6):699-707.

PMID:
17074738
33.

Absence of Y-chromosome sequences in tumors from African women with AIDS-related Kaposi sarcoma.

Mbulaiteye SM, Sternberg LR, Nsubuga MM, Anver MR, Mehta M, Biryahwaho B, Kambugu F, Rabkin CS, Biggar RJ.

Cancer Lett. 2007 Apr 18;248(2):229-33. Epub 2006 Aug 24.

PMID:
16934394
34.

Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations.

Hruban RH, Adsay NV, Albores-Saavedra J, Anver MR, Biankin AV, Boivin GP, Furth EE, Furukawa T, Klein A, Klimstra DS, Kloppel G, Lauwers GY, Longnecker DS, Luttges J, Maitra A, Offerhaus GJ, Pérez-Gallego L, Redston M, Tuveson DA.

Cancer Res. 2006 Jan 1;66(1):95-106.

35.

Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity.

Sun K, Wilkins DE, Anver MR, Sayers TJ, Panoskaltsis-Mortari A, Blazar BR, Welniak LA, Murphy WJ.

Blood. 2005 Nov 1;106(9):3293-9. Epub 2005 Jun 16.

36.

Gadd45a acts as a modifier locus for lymphoblastic lymphoma.

Hollander MC, Patterson AD, Salvador JM, Anver MR, Hunger SP, Fornace AJ.

Leukemia. 2005 May;19(5):847-50.

PMID:
15744335
37.

Mammary development and tumorigenesis in mice expressing a truncated human Notch4/Int3 intracellular domain (h-Int3sh).

Raafat A, Bargo S, Anver MR, Callahan R.

Oncogene. 2004 Dec 16;23(58):9401-7.

PMID:
15531924
38.

Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortium.

Nikitin AY, Alcaraz A, Anver MR, Bronson RT, Cardiff RD, Dixon D, Fraire AE, Gabrielson EW, Gunning WT, Haines DC, Kaufman MH, Linnoila RI, Maronpot RR, Rabson AS, Reddick RL, Rehm S, Rozengurt N, Schuller HM, Shmidt EN, Travis WD, Ward JM, Jacks T.

Cancer Res. 2004 Apr 1;64(7):2307-16. Review. Erratum in: Cancer Res. 2004 May 15;64(10):3725.

39.

An absence of CCR5 on donor cells results in acceleration of acute graft-vs-host disease.

Welniak LA, Wang Z, Sun K, Kuziel W, Anver MR, Blazar BR, Murphy WJ.

Exp Hematol. 2004 Mar;32(3):318-24.

PMID:
15003318
40.

A novel retrovirus provides the cooperating oncogenic event(s) required to demonstrate the tumor suppressor activity of p15Ink4b in myeloid cells in vivo.

Wolff L, Garin MT, Koller R, Bies J, Tessarollo L, Anver MR, Powell D, Perella C.

Blood Cells Mol Dis. 2004 Jan-Feb;32(1):226-31.

PMID:
14757439
41.

Effects of organ-specific loss of insulin-like growth factor-I production on murine hematopoiesis.

Welniak LA, Karas M, Yakar S, Anver MR, Murphy WJ, LeRoith D.

Biol Blood Marrow Transplant. 2004 Jan;10(1):32-9.

42.

Specific excision of the selenocysteine tRNA[Ser]Sec (Trsp) gene in mouse liver demonstrates an essential role of selenoproteins in liver function.

Carlson BA, Novoselov SV, Kumaraswamy E, Lee BJ, Anver MR, Gladyshev VN, Hatfield DL.

J Biol Chem. 2004 Feb 27;279(9):8011-7. Epub 2003 Dec 4.

43.

Spontaneous pituitary abnormalities and mammary hyperplasia in FVB/NCr mice: implications for mouse modeling.

Wakefield LM, Thordarson G, Nieto AI, Shyamala G, Galvez JJ, Anver MR, Cardiff RD.

Comp Med. 2003 Aug;53(4):424-32.

PMID:
14524419
44.

TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression.

Tang B, Vu M, Booker T, Santner SJ, Miller FR, Anver MR, Wakefield LM.

J Clin Invest. 2003 Oct;112(7):1116-24.

46.

Gadd45a protects against UV irradiation-induced skin tumors, and promotes apoptosis and stress signaling via MAPK and p53.

Hildesheim J, Bulavin DV, Anver MR, Alvord WG, Hollander MC, Vardanian L, Fornace AJ Jr.

Cancer Res. 2002 Dec 15;62(24):7305-15.

48.

Ink4a/arf deficiency promotes ultraviolet radiation-induced melanomagenesis.

Recio JA, Noonan FP, Takayama H, Anver MR, Duray P, Rush WL, Lindner G, De Fabo EC, DePinho RA, Merlino G.

Cancer Res. 2002 Nov 15;62(22):6724-30.

49.

Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut.

Hixon JA, Anver MR, Blazar BR, Panoskaltsis-Mortari A, Wiltrout RH, Murphy WJ.

Biol Blood Marrow Transplant. 2002;8(6):316-25.

50.

Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects.

Yang YA, Dukhanina O, Tang B, Mamura M, Letterio JJ, MacGregor J, Patel SC, Khozin S, Liu ZY, Green J, Anver MR, Merlino G, Wakefield LM.

J Clin Invest. 2002 Jun;109(12):1607-15.

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