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Items: 1 to 50 of 488

1.

Author Correction: Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39.

Takenaka MC, Gabriely G, Rothhammer V, Mascanfroni ID, Wheeler MA, Chao CC, Gutiérrez-Vázquez C, Kenison J, Tjon EC, Barroso A, Vandeventer T, de Lima KA, Rothweiler S, Mayo L, Ghannam S, Zandee S, Healy L, Sherr D, Farez MF, Prat A, Antel J, Reardon DA, Zhang H, Robson SC, Getz G, Weiner HL, Quintana FJ.

Nat Neurosci. 2019 Jun 13. doi: 10.1038/s41593-019-0446-8. [Epub ahead of print]

PMID:
31197266
2.

Clinical Trials Required to Assess Potential Benefits and Side Effects of Treatment of Patients With Anorexia Nervosa With Recombinant Human Leptin.

Hebebrand J, Milos G, Wabitsch M, Teufel M, Führer D, Bühlmeier J, Libuda L, Ludwig C, Antel J.

Front Psychol. 2019 May 17;10:769. doi: 10.3389/fpsyg.2019.00769. eCollection 2019. Review.

3.

Vitamin D and the Risk of Depression: A Causal Relationship? Findings from a Mendelian Randomization Study.

Libuda L, Laabs BH, Ludwig C, Bühlmeier J, Antel J, Hinney A, Naaresh R, Föcker M, Hebebrand J, König IR, Peters T.

Nutrients. 2019 May 16;11(5). pii: E1085. doi: 10.3390/nu11051085.

4.

Distinct Function-Related Molecular Profile of Adult Human A2B5-Positive Pre-Oligodendrocytes Versus Mature Oligodendrocytes.

Esmonde-White C, Yaqubi M, Bilodeau PA, Cui QL, Pernin F, Larochelle C, Ghadiri M, Xu YKT, Kennedy TE, Hall J, Healy LM, Antel JP.

J Neuropathol Exp Neurol. 2019 Jun 1;78(6):468-479. doi: 10.1093/jnen/nlz026.

PMID:
31058285
5.

Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39.

Takenaka MC, Gabriely G, Rothhammer V, Mascanfroni ID, Wheeler MA, Chao CC, Gutiérrez-Vázquez C, Kenison J, Tjon EC, Barroso A, Vandeventer T, de Lima KA, Rothweiler S, Mayo L, Ghannam S, Zandee S, Healy L, Sherr D, Farez MF, Prat A, Antel J, Reardon DA, Zhang H, Robson SC, Getz G, Weiner HL, Quintana FJ.

Nat Neurosci. 2019 May;22(5):729-740. doi: 10.1038/s41593-019-0370-y. Epub 2019 Apr 8. Erratum in: Nat Neurosci. 2019 Jun 13;:.

PMID:
30962630
6.

Deep learning for high-throughput quantification of oligodendrocyte ensheathment at single-cell resolution.

Xu YKT, Chitsaz D, Brown RA, Cui QL, Dabarno MA, Antel JP, Kennedy TE.

Commun Biol. 2019 Mar 26;2:116. doi: 10.1038/s42003-019-0356-z. eCollection 2019.

7.

MSJ 2019 - Editorial comment.

Thompson AJ, Antel J, Carroll WB, Geurts J.

Mult Scler. 2019 Jan;25(1):4-5. doi: 10.1177/1352458518819096. No abstract available.

PMID:
30799696
8.

Correction: Dimethyl Fumarate Treatment Mediates an Anti-Inflammatory Shift in B Cell Subsets of Patients with Multiple Sclerosis.

Li R, Rezk A, Ghadiri M, Luessi F, Zipp F, Li H, Giacomini PS, Antel J, Bar-Or A.

J Immunol. 2019 Apr 1;202(7):2172. doi: 10.4049/jimmunol.1900114. Epub 2019 Feb 15. No abstract available.

PMID:
30770414
9.

Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation.

Wheeler MA, Jaronen M, Covacu R, Zandee SEJ, Scalisi G, Rothhammer V, Tjon EC, Chao CC, Kenison JE, Blain M, Rao VTS, Hewson P, Barroso A, Gutiérrez-Vázquez C, Prat A, Antel JP, Hauser R, Quintana FJ.

Cell. 2019 Jan 24;176(3):581-596.e18. doi: 10.1016/j.cell.2018.12.012. Epub 2019 Jan 17.

PMID:
30661753
10.

Placebo response rates and potential modifiers in double-blind randomized controlled trials of second and newer generation antidepressants for major depressive disorder in children and adolescents: a systematic review and meta-regression analysis.

Meister R, Abbas M, Antel J, Peters T, Pan Y, Bingel U, Nestoriuc Y, Hebebrand J.

Eur Child Adolesc Psychiatry. 2018 Dec 8. doi: 10.1007/s00787-018-1244-7. [Epub ahead of print] Review.

PMID:
30535589
11.

Helper CD4 T cells expressing granzyme B cause glial fibrillary acidic protein fragmentation in astrocytes in an MHCII-independent manner.

Stopnicki B, Blain M, Cui QL, Kennedy TE, Antel JP, Healy LM, Darlington PJ.

Glia. 2019 Apr;67(4):582-593. doi: 10.1002/glia.23503. Epub 2018 Nov 16.

PMID:
30444064
12.

Peripherally derived macrophages modulate microglial function to reduce inflammation after CNS injury.

Greenhalgh AD, Zarruk JG, Healy LM, Baskar Jesudasan SJ, Jhelum P, Salmon CK, Formanek A, Russo MV, Antel JP, McGavern DB, McColl BW, David S.

PLoS Biol. 2018 Oct 17;16(10):e2005264. doi: 10.1371/journal.pbio.2005264. eCollection 2018 Oct.

13.

2018 Editors' commentary.

Thompson A, Antel J, Carroll WM, Geurts JJ.

Mult Scler. 2018 Oct;24(11):1394-1395. doi: 10.1177/1352458518801764. No abstract available.

PMID:
30289380
14.

The association of serum leptin levels with food addiction is moderated by weight status in adolescent psychiatric inpatients.

Peters T, Antel J, Föcker M, Esber S, Hinney A, Schéle E, Dickson SL, Albayrak Ö, Hebebrand J.

Eur Eat Disord Rev. 2018 Nov;26(6):618-628. doi: 10.1002/erv.2637. Epub 2018 Sep 4.

PMID:
30252189
15.

Therapy in Multiple Sclerosis - Coming of Age.

Antel J.

N Engl J Med. 2018 Sep 13;379(11):1085-1086. doi: 10.1056/NEJMe1810019. No abstract available.

PMID:
30207922
16.

Microglial control of astrocytes in response to microbial metabolites.

Rothhammer V, Borucki DM, Tjon EC, Takenaka MC, Chao CC, Ardura-Fabregat A, de Lima KA, Gutiérrez-Vázquez C, Hewson P, Staszewski O, Blain M, Healy L, Neziraj T, Borio M, Wheeler M, Dragin LL, Laplaud DA, Antel J, Alvarez JI, Prinz M, Quintana FJ.

Nature. 2018 May;557(7707):724-728. doi: 10.1038/s41586-018-0119-x. Epub 2018 May 16.

17.

The role of genetic variation of human metabolism for BMI, mental traits and mental disorders.

Hebebrand J, Peters T, Schijven D, Hebebrand M, Grasemann C, Winkler TW, Heid IM, Antel J, Föcker M, Tegeler L, Brauner L, Adan RAH, Luykx JJ, Correll CU, König IR, Hinney A, Libuda L.

Mol Metab. 2018 Jun;12:1-11. doi: 10.1016/j.molmet.2018.03.015. Epub 2018 Apr 3.

18.

Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis.

Touil H, Kobert A, Lebeurrier N, Rieger A, Saikali P, Lambert C, Fawaz L, Moore CS, Prat A, Gommerman J, Antel JP, Itoyama Y, Nakashima I, Bar-Or A; Canadian B Cell Team in MS.

J Neuroinflammation. 2018 Apr 19;15(1):114. doi: 10.1186/s12974-018-1136-2.

19.

Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes.

Gabrusiewicz K, Li X, Wei J, Hashimoto Y, Marisetty AL, Ott M, Wang F, Hawke D, Yu J, Healy LM, Hossain A, Akers JC, Maiti SN, Yamashita S, Shimizu Y, Dunner K, Zal MA, Burks JK, Gumin J, Nwajei F, Rezavanian A, Zhou S, Rao G, Sawaya R, Fuller GN, Huse JT, Antel JP, Li S, Cooper L, Sulman EP, Chen C, Geula C, Kalluri R, Zal T, Heimberger AB.

Oncoimmunology. 2018 Jan 16;7(4):e1412909. doi: 10.1080/2162402X.2017.1412909. eCollection 2018.

20.

The Effect of SH2B1 Variants on Expression of Leptin- and Insulin-Induced Pathways in Murine Hypothalamus.

Giuranna J, Volckmar AL, Heinen A, Peters T, Schmidt B, Spieker A, Straub H, Grallert H, Müller TD, Antel J, Haußmann U, Klafki H, Rui L, Hebebrand J, Hinney A.

Obes Facts. 2018;11(2):93-108. doi: 10.1159/000486962. Epub 2018 Apr 10. Erratum in: Obes Facts. 2018;11(3):176-180.

21.

Immunology of oligodendrocyte precursor cells in vivo and in vitro.

Antel JP, Lin YH, Cui QL, Pernin F, Kennedy TE, Ludwin SK, Healy LM.

J Neuroimmunol. 2019 Jun 15;331:28-35. doi: 10.1016/j.jneuroim.2018.03.006. Epub 2018 Mar 13.

PMID:
29566973
22.

The reality of "ghosts" in authorship of clinical trials in multiple sclerosis.

Antel J.

Ann Neurol. 2018 Apr;83(4):656-657. doi: 10.1002/ana.25199. No abstract available.

PMID:
29534308
23.

Effect of an vitamin D deficiency on depressive symptoms in child and adolescent psychiatric patients - a randomized controlled trial: study protocol.

Föcker M, Antel J, Grasemann C, Führer D, Timmesfeld N, Öztürk D, Peters T, Hinney A, Hebebrand J, Libuda L.

BMC Psychiatry. 2018 Mar 1;18(1):57. doi: 10.1186/s12888-018-1637-7.

24.

MSJ 2018-editorial comment.

Thompson AJ, Antel J, Carroll WM, Geurts J.

Mult Scler. 2018 Feb;24(2):90-91. doi: 10.1177/1352458518756517. No abstract available.

PMID:
29451441
25.

MerTK-mediated regulation of myelin phagocytosis by macrophages generated from patients with MS.

Healy LM, Jang JH, Won SY, Lin YH, Touil H, Aljarallah S, Bar-Or A, Antel JP.

Neurol Neuroimmunol Neuroinflamm. 2017 Oct 16;4(6):e402. doi: 10.1212/NXI.0000000000000402. eCollection 2017 Nov.

26.
27.

Corrigendum: Divergent Neuroinflammatory Regulation of Microglial TREM Expression and Involvement of NF-κB.

Owens R, Grabert K, Davies CL, Alfieri A, Antel JP, Healy LM, McColl BW.

Front Cell Neurosci. 2017 Aug 24;11:256. doi: 10.3389/fncel.2017.00256. eCollection 2017.

28.

α7 nicotinic acetylcholine receptor signaling modulates the inflammatory phenotype of fetal brain microglia: first evidence of interference by iron homeostasis.

Cortes M, Cao M, Liu HL, Moore CS, Durosier LD, Burns P, Fecteau G, Desrochers A, Barreiro LB, Antel JP, Frasch MG.

Sci Rep. 2017 Sep 6;7(1):10645. doi: 10.1038/s41598-017-09439-z.

29.

Low 25(OH)-vitamin D concentrations are associated with emotional and behavioral problems in German children and adolescents.

Husmann C, Frank M, Schmidt B, Jöckel KH, Antel J, Reissner V, Libuda L, Hebebrand J, Föcker M.

PLoS One. 2017 Aug 23;12(8):e0183091. doi: 10.1371/journal.pone.0183091. eCollection 2017.

30.

Distinct age and differentiation-state dependent metabolic profiles of oligodendrocytes under optimal and stress conditions.

Rao VTS, Khan D, Cui QL, Fuh SC, Hossain S, Almazan G, Multhaup G, Healy LM, Kennedy TE, Antel JP.

PLoS One. 2017 Aug 8;12(8):e0182372. doi: 10.1371/journal.pone.0182372. eCollection 2017.

31.

Reconstitution of the peripheral immune repertoire following withdrawal of fingolimod.

Ghadiri M, Fitz-Gerald L, Rezk A, Li R, Nyirenda M, Haegert D, Giacomini PS, Bar-Or A, Antel J.

Mult Scler. 2017 Aug;23(9):1225-1232. doi: 10.1177/1352458517713147.

PMID:
28749311
32.

Comparative morphology and phagocytic capacity of primary human adult microglia with time-lapse imaging.

Levtova N, Healy LM, Gonczi CMC, Stopnicki B, Blain M, Kennedy TE, Moore CS, Antel JP, Darlington PJ.

J Neuroimmunol. 2017 Sep 15;310:143-149. doi: 10.1016/j.jneuroim.2017.05.012. Epub 2017 May 22.

PMID:
28606377
33.

A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response.

Haenseler W, Sansom SN, Buchrieser J, Newey SE, Moore CS, Nicholls FJ, Chintawar S, Schnell C, Antel JP, Allen ND, Cader MZ, Wade-Martins R, James WS, Cowley SA.

Stem Cell Reports. 2017 Jun 6;8(6):1727-1742. doi: 10.1016/j.stemcr.2017.05.017.

34.

Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans.

Owen DR, Narayan N, Wells L, Healy L, Smyth E, Rabiner EA, Galloway D, Williams JB, Lehr J, Mandhair H, Peferoen LA, Taylor PC, Amor S, Antel JP, Matthews PM, Moore CS.

J Cereb Blood Flow Metab. 2017 Aug;37(8):2679-2690. doi: 10.1177/0271678X17710182. Epub 2017 May 22.

35.

Sublethal oligodendrocyte injury: A reversible condition in multiple sclerosis?

Cui QL, Khan D, Rone M, T S Rao V, Johnson RM, Lin YH, Bilodeau PA, Hall JA, Rodriguez M, Kennedy TE, Ludwin SK, Antel JP.

Ann Neurol. 2017 Jun;81(6):811-824. doi: 10.1002/ana.24944. Epub 2017 Jun 2.

PMID:
28470695
36.

iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases.

Abud EM, Ramirez RN, Martinez ES, Healy LM, Nguyen CHH, Newman SA, Yeromin AV, Scarfone VM, Marsh SE, Fimbres C, Caraway CA, Fote GM, Madany AM, Agrawal A, Kayed R, Gylys KH, Cahalan MD, Cummings BJ, Antel JP, Mortazavi A, Carson MJ, Poon WW, Blurton-Jones M.

Neuron. 2017 Apr 19;94(2):278-293.e9. doi: 10.1016/j.neuron.2017.03.042.

37.

Dimethyl fumarate-induced lymphopenia in MS due to differential T-cell subset apoptosis.

Ghadiri M, Rezk A, Li R, Evans A, Luessi F, Zipp F, Giacomini PS, Antel J, Bar-Or A.

Neurol Neuroimmunol Neuroinflamm. 2017 Mar 23;4(3):e340. doi: 10.1212/NXI.0000000000000340. eCollection 2017 May.

38.

Divergent Neuroinflammatory Regulation of Microglial TREM Expression and Involvement of NF-κB.

Owens R, Grabert K, Davies CL, Alfieri A, Antel JP, Healy LM, McColl BW.

Front Cell Neurosci. 2017 Mar 2;11:56. doi: 10.3389/fncel.2017.00056. eCollection 2017. Erratum in: Front Cell Neurosci. 2017 Aug 24;11:256.

39.

Small-Molecule Stabilization of 14-3-3 Protein-Protein Interactions Stimulates Axon Regeneration.

Kaplan A, Morquette B, Kroner A, Leong S, Madwar C, Sanz R, Banerjee SL, Antel J, Bisson N, David S, Fournier AE.

Neuron. 2017 Mar 8;93(5):1082-1093.e5. doi: 10.1016/j.neuron.2017.02.018.

40.

Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors.

Ehrlich M, Mozafari S, Glatza M, Starost L, Velychko S, Hallmann AL, Cui QL, Schambach A, Kim KP, Bachelin C, Marteyn A, Hargus G, Johnson RM, Antel J, Sterneckert J, Zaehres H, Schöler HR, Baron-Van Evercooren A, Kuhlmann T.

Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2243-E2252. doi: 10.1073/pnas.1614412114. Epub 2017 Feb 28.

41.

Vitamin D and mental health in children and adolescents.

Föcker M, Antel J, Ring S, Hahn D, Kanal Ö, Öztürk D, Hebebrand J, Libuda L.

Eur Child Adolesc Psychiatry. 2017 Sep;26(9):1043-1066. doi: 10.1007/s00787-017-0949-3. Epub 2017 Feb 8. Review.

PMID:
28176022
42.

Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation.

Rothhammer V, Kenison JE, Tjon E, Takenaka MC, de Lima KA, Borucki DM, Chao CC, Wilz A, Blain M, Healy L, Antel J, Quintana FJ.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):2012-2017. doi: 10.1073/pnas.1615413114. Epub 2017 Feb 6.

43.

Editorial 2017.

Thompson A, Antel J, Carroll WB, Geurts J.

Mult Scler. 2017 Jan;23(1):4. doi: 10.1177/1352458516688643. No abstract available.

PMID:
28102787
44.

[Nutrition and mental diseases : Focus depressive disorders].

Libuda L, Antel J, Hebebrand J, Föcker M.

Nervenarzt. 2017 Jan;88(1):87-101. doi: 10.1007/s00115-016-0262-2. Review. German.

PMID:
28005145
45.

An updated histological classification system for multiple sclerosis lesions.

Kuhlmann T, Ludwin S, Prat A, Antel J, Brück W, Lassmann H.

Acta Neuropathol. 2017 Jan;133(1):13-24. doi: 10.1007/s00401-016-1653-y. Epub 2016 Dec 17.

PMID:
27988845
46.

Dimethyl Fumarate Treatment Mediates an Anti-Inflammatory Shift in B Cell Subsets of Patients with Multiple Sclerosis.

Li R, Rezk A, Ghadiri M, Luessi F, Zipp F, Li H, Giacomini PS, Antel J, Bar-Or A.

J Immunol. 2017 Jan 15;198(2):691-698. doi: 10.4049/jimmunol.1601649. Epub 2016 Dec 14. Erratum in: J Immunol. 2019 Apr 1;202(7):2172.

47.

RNAseq profiling of primary microglia and astrocyte cultures in near-term ovine fetus: A glial in vivo-in vitro multi-hit paradigm in large mammalian brain.

Cortes M, Cao M, Liu HL, Burns P, Moore C, Fecteau G, Desrochers A, Barreiro LB, Antel JP, Frasch MG.

J Neurosci Methods. 2017 Jan 30;276:23-32. doi: 10.1016/j.jneumeth.2016.11.008. Epub 2016 Nov 14.

48.

Erratum: USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.

Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, Arbour N, Prat A, Majewski J, Lathrop M, Vidal SM, Gros P.

Nat Immunol. 2016 Nov 16;17(12):1479. doi: 10.1038/ni1216-1479c. No abstract available.

PMID:
27849203
49.

USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.

Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, Arbour N, Prat A, Majewski J, Lathrop M, Vidal SM, Gros P.

Nat Immunol. 2017 Jan;18(1):54-63. doi: 10.1038/ni.3581. Epub 2016 Oct 10. Erratum in: Nat Immunol. 2016 Nov 16;17 (12 ):1479.

PMID:
27721430
50.

Synaptic pathology in the cerebellar dentate nucleus in chronic multiple sclerosis.

Albert M, Barrantes-Freer A, Lohrberg M, Antel JP, Prineas JW, Palkovits M, Wolff JR, Brück W, Stadelmann C.

Brain Pathol. 2017 Nov;27(6):737-747. doi: 10.1111/bpa.12450. Epub 2017 Mar 6.

PMID:
27706868

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