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Items: 1 to 50 of 499

1.

RNA-binding protein altered expression and mislocalization in MS.

Masaki K, Sonobe Y, Ghadge G, Pytel P, Lépine P, Pernin F, Cui QL, Antel JP, Zandee S, Prat A, Roos RP.

Neurol Neuroimmunol Neuroinflamm. 2020 Mar 26;7(3). pii: e704. doi: 10.1212/NXI.0000000000000704. Print 2020 May.

2.

Effect of vitamin D deficiency on depressive symptoms in child and adolescent psychiatric patients: results of a randomized controlled trial.

Libuda L, Timmesfeld N, Antel J, Hirtz R, Bauer J, Führer D, Zwanziger D, Öztürk D, Langenbach G, Hahn D, Ring S, Peters T, Hinney A, Bühlmeier J, Hebebrand J, Grasemann C, Föcker M.

Eur J Nutr. 2020 Feb 27. doi: 10.1007/s00394-020-02176-6. [Epub ahead of print]

PMID:
32108263
3.

MAFG-driven astrocytes promote CNS inflammation.

Wheeler MA, Clark IC, Tjon EC, Li Z, Zandee SEJ, Couturier CP, Watson BR, Scalisi G, Alkwai S, Rothhammer V, Rotem A, Heyman JA, Thaploo S, Sanmarco LM, Ragoussis J, Weitz DA, Petrecca K, Moffitt JR, Becher B, Antel JP, Prat A, Quintana FJ.

Nature. 2020 Feb;578(7796):593-599. doi: 10.1038/s41586-020-1999-0. Epub 2020 Feb 12.

PMID:
32051591
4.

Developmental trajectory of oligodendrocyte progenitor cells in the human brain revealed by single cell RNA sequencing.

Perlman K, Couturier CP, Yaqubi M, Tanti A, Cui QL, Pernin F, Stratton JA, Ragoussis J, Healy L, Petrecca K, Dudley R, Srour M, Hall JA, Kennedy TE, Mechawar N, Antel JP.

Glia. 2020 Jan 20. doi: 10.1002/glia.23777. [Epub ahead of print]

PMID:
31958186
5.

Pre-treatment T-cell subsets associate with fingolimod treatment responsiveness in multiple sclerosis.

Ghadiri M, Rezk A, Li R, Evans A, Giacomini PS, Barnett MH, Antel J, Bar-Or A.

Sci Rep. 2020 Jan 15;10(1):356. doi: 10.1038/s41598-019-57114-2.

6.

Extensive subpial cortical demyelination is specific to multiple sclerosis.

Junker A, Wozniak J, Voigt D, Scheidt U, Antel J, Wegner C, Brück W, Stadelmann C.

Brain Pathol. 2020 Jan 8. doi: 10.1111/bpa.12813. [Epub ahead of print]

PMID:
31916298
7.

Glial Cells as Regulators of Neuroimmune Interactions in the Central Nervous System.

Antel JP, Becher B, Ludwin SK, Prat A, Quintana FJ.

J Immunol. 2020 Jan 15;204(2):251-255. doi: 10.4049/jimmunol.1900908. No abstract available.

PMID:
31907266
8.

Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS.

Chao CC, Gutiérrez-Vázquez C, Rothhammer V, Mayo L, Wheeler MA, Tjon EC, Zandee SEJ, Blain M, de Lima KA, Takenaka MC, Avila-Pacheco J, Hewson P, Liu L, Sanmarco LM, Borucki DM, Lipof GZ, Trauger SA, Clish CB, Antel JP, Prat A, Quintana FJ.

Cell. 2019 Dec 12;179(7):1483-1498.e22. doi: 10.1016/j.cell.2019.11.016. Epub 2019 Dec 5.

PMID:
31813625
9.

Species differences in immune-mediated CNS tissue injury and repair: A (neuro)inflammatory topic.

Healy LM, Yaqubi M, Ludwin S, Antel JP.

Glia. 2020 Apr;68(4):811-829. doi: 10.1002/glia.23746. Epub 2019 Nov 14.

PMID:
31724770
10.

Astrocytes in the Pathogenesis of Multiple Sclerosis: An In Situ MicroRNA Study.

Rao VTS, Fuh SC, Karamchandani JR, Woulfe JMJ, Munoz DG, Ellezam B, Blain M, Ho MK, Bedell BJ, Antel JP, Ludwin SK.

J Neuropathol Exp Neurol. 2019 Dec 1;78(12):1130-1146. doi: 10.1093/jnen/nlz098.

PMID:
31665376
11.

Assessing causal links between metabolic traits, inflammation and schizophrenia: a univariable and multivariable, bidirectional Mendelian-randomization study.

Lin BD, Alkema A, Peters T, Zinkstok J, Libuda L, Hebebrand J, Antel J, Hinney A, Cahn W, Adan R, Luykx JJ.

Int J Epidemiol. 2019 Oct 1;48(5):1505-1514. doi: 10.1093/ije/dyz176.

12.

T follicular helper cells in human efferent lymph retain lymphoid characteristics.

Vella LA, Buggert M, Manne S, Herati RS, Sayin I, Kuri-Cervantes L, Bukh Brody I, O'Boyle KC, Kaprielian H, Giles JR, Nguyen S, Muselman A, Antel JP, Bar-Or A, Johnson ME, Canaday DH, Naji A, Ganusov VV, Laufer TM, Wells AD, Dori Y, Itkin MG, Betts MR, Wherry EJ.

J Clin Invest. 2019 Jul 2;129(8):3185-3200. doi: 10.1172/JCI125628. eCollection 2019 Jul 2.

13.

Author Correction: Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39.

Takenaka MC, Gabriely G, Rothhammer V, Mascanfroni ID, Wheeler MA, Chao CC, Gutiérrez-Vázquez C, Kenison J, Tjon EC, Barroso A, Vandeventer T, de Lima KA, Rothweiler S, Mayo L, Ghannam S, Zandee S, Healy L, Sherr D, Farez MF, Prat A, Antel J, Reardon DA, Zhang H, Robson SC, Getz G, Weiner HL, Quintana FJ.

Nat Neurosci. 2019 Sep;22(9):1533. doi: 10.1038/s41593-019-0446-8.

PMID:
31197266
14.

Clinical Trials Required to Assess Potential Benefits and Side Effects of Treatment of Patients With Anorexia Nervosa With Recombinant Human Leptin.

Hebebrand J, Milos G, Wabitsch M, Teufel M, Führer D, Bühlmeier J, Libuda L, Ludwig C, Antel J.

Front Psychol. 2019 May 17;10:769. doi: 10.3389/fpsyg.2019.00769. eCollection 2019. Review.

15.

Vitamin D and the Risk of Depression: A Causal Relationship? Findings from a Mendelian Randomization Study.

Libuda L, Laabs BH, Ludwig C, Bühlmeier J, Antel J, Hinney A, Naaresh R, Föcker M, Hebebrand J, König IR, Peters T.

Nutrients. 2019 May 16;11(5). pii: E1085. doi: 10.3390/nu11051085.

16.

Distinct Function-Related Molecular Profile of Adult Human A2B5-Positive Pre-Oligodendrocytes Versus Mature Oligodendrocytes.

Esmonde-White C, Yaqubi M, Bilodeau PA, Cui QL, Pernin F, Larochelle C, Ghadiri M, Xu YKT, Kennedy TE, Hall J, Healy LM, Antel JP.

J Neuropathol Exp Neurol. 2019 Jun 1;78(6):468-479. doi: 10.1093/jnen/nlz026.

PMID:
31058285
17.

Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39.

Takenaka MC, Gabriely G, Rothhammer V, Mascanfroni ID, Wheeler MA, Chao CC, Gutiérrez-Vázquez C, Kenison J, Tjon EC, Barroso A, Vandeventer T, de Lima KA, Rothweiler S, Mayo L, Ghannam S, Zandee S, Healy L, Sherr D, Farez MF, Prat A, Antel J, Reardon DA, Zhang H, Robson SC, Getz G, Weiner HL, Quintana FJ.

Nat Neurosci. 2019 May;22(5):729-740. doi: 10.1038/s41593-019-0370-y. Epub 2019 Apr 8. Erratum in: Nat Neurosci. 2019 Sep;22(9):1533.

PMID:
30962630
18.

Deep learning for high-throughput quantification of oligodendrocyte ensheathment at single-cell resolution.

Xu YKT, Chitsaz D, Brown RA, Cui QL, Dabarno MA, Antel JP, Kennedy TE.

Commun Biol. 2019 Mar 26;2:116. doi: 10.1038/s42003-019-0356-z. eCollection 2019.

19.

MSJ 2019 - Editorial comment.

Thompson AJ, Antel J, Carroll WB, Geurts J.

Mult Scler. 2019 Jan;25(1):4-5. doi: 10.1177/1352458518819096. No abstract available.

PMID:
30799696
20.

Correction: Dimethyl Fumarate Treatment Mediates an Anti-Inflammatory Shift in B Cell Subsets of Patients with Multiple Sclerosis.

Li R, Rezk A, Ghadiri M, Luessi F, Zipp F, Li H, Giacomini PS, Antel J, Bar-Or A.

J Immunol. 2019 Apr 1;202(7):2172. doi: 10.4049/jimmunol.1900114. Epub 2019 Feb 15. No abstract available.

PMID:
30770414
21.

Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation.

Wheeler MA, Jaronen M, Covacu R, Zandee SEJ, Scalisi G, Rothhammer V, Tjon EC, Chao CC, Kenison JE, Blain M, Rao VTS, Hewson P, Barroso A, Gutiérrez-Vázquez C, Prat A, Antel JP, Hauser R, Quintana FJ.

Cell. 2019 Jan 24;176(3):581-596.e18. doi: 10.1016/j.cell.2018.12.012. Epub 2019 Jan 17.

22.

Placebo response rates and potential modifiers in double-blind randomized controlled trials of second and newer generation antidepressants for major depressive disorder in children and adolescents: a systematic review and meta-regression analysis.

Meister R, Abbas M, Antel J, Peters T, Pan Y, Bingel U, Nestoriuc Y, Hebebrand J.

Eur Child Adolesc Psychiatry. 2020 Mar;29(3):253-273. doi: 10.1007/s00787-018-1244-7. Epub 2018 Dec 8. Review.

23.

Helper CD4 T cells expressing granzyme B cause glial fibrillary acidic protein fragmentation in astrocytes in an MHCII-independent manner.

Stopnicki B, Blain M, Cui QL, Kennedy TE, Antel JP, Healy LM, Darlington PJ.

Glia. 2019 Apr;67(4):582-593. doi: 10.1002/glia.23503. Epub 2018 Nov 16.

PMID:
30444064
24.

Peripherally derived macrophages modulate microglial function to reduce inflammation after CNS injury.

Greenhalgh AD, Zarruk JG, Healy LM, Baskar Jesudasan SJ, Jhelum P, Salmon CK, Formanek A, Russo MV, Antel JP, McGavern DB, McColl BW, David S.

PLoS Biol. 2018 Oct 17;16(10):e2005264. doi: 10.1371/journal.pbio.2005264. eCollection 2018 Oct.

25.

2018 Editors' commentary.

Thompson A, Antel J, Carroll WM, Geurts JJ.

Mult Scler. 2018 Oct;24(11):1394-1395. doi: 10.1177/1352458518801764. No abstract available.

PMID:
30289380
26.

The association of serum leptin levels with food addiction is moderated by weight status in adolescent psychiatric inpatients.

Peters T, Antel J, Föcker M, Esber S, Hinney A, Schéle E, Dickson SL, Albayrak Ö, Hebebrand J.

Eur Eat Disord Rev. 2018 Nov;26(6):618-628. doi: 10.1002/erv.2637. Epub 2018 Sep 4.

PMID:
30252189
27.

Therapy in Multiple Sclerosis - Coming of Age.

Antel J.

N Engl J Med. 2018 Sep 13;379(11):1085-1086. doi: 10.1056/NEJMe1810019. No abstract available.

PMID:
30207922
28.

Microglial control of astrocytes in response to microbial metabolites.

Rothhammer V, Borucki DM, Tjon EC, Takenaka MC, Chao CC, Ardura-Fabregat A, de Lima KA, Gutiérrez-Vázquez C, Hewson P, Staszewski O, Blain M, Healy L, Neziraj T, Borio M, Wheeler M, Dragin LL, Laplaud DA, Antel J, Alvarez JI, Prinz M, Quintana FJ.

Nature. 2018 May;557(7707):724-728. doi: 10.1038/s41586-018-0119-x. Epub 2018 May 16.

29.

The role of genetic variation of human metabolism for BMI, mental traits and mental disorders.

Hebebrand J, Peters T, Schijven D, Hebebrand M, Grasemann C, Winkler TW, Heid IM, Antel J, Föcker M, Tegeler L, Brauner L, Adan RAH, Luykx JJ, Correll CU, König IR, Hinney A, Libuda L.

Mol Metab. 2018 Jun;12:1-11. doi: 10.1016/j.molmet.2018.03.015. Epub 2018 Apr 3.

30.

Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis.

Touil H, Kobert A, Lebeurrier N, Rieger A, Saikali P, Lambert C, Fawaz L, Moore CS, Prat A, Gommerman J, Antel JP, Itoyama Y, Nakashima I, Bar-Or A; Canadian B Cell Team in MS.

J Neuroinflammation. 2018 Apr 19;15(1):114. doi: 10.1186/s12974-018-1136-2.

31.

Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes.

Gabrusiewicz K, Li X, Wei J, Hashimoto Y, Marisetty AL, Ott M, Wang F, Hawke D, Yu J, Healy LM, Hossain A, Akers JC, Maiti SN, Yamashita S, Shimizu Y, Dunner K, Zal MA, Burks JK, Gumin J, Nwajei F, Rezavanian A, Zhou S, Rao G, Sawaya R, Fuller GN, Huse JT, Antel JP, Li S, Cooper L, Sulman EP, Chen C, Geula C, Kalluri R, Zal T, Heimberger AB.

Oncoimmunology. 2018 Jan 16;7(4):e1412909. doi: 10.1080/2162402X.2017.1412909. eCollection 2018.

32.

The Effect of SH2B1 Variants on Expression of Leptin- and Insulin-Induced Pathways in Murine Hypothalamus.

Giuranna J, Volckmar AL, Heinen A, Peters T, Schmidt B, Spieker A, Straub H, Grallert H, Müller TD, Antel J, Haußmann U, Klafki H, Rui L, Hebebrand J, Hinney A.

Obes Facts. 2018;11(2):93-108. doi: 10.1159/000486962. Epub 2018 Apr 10. Erratum in: Obes Facts. 2018;11(3):176-180.

33.

Immunology of oligodendrocyte precursor cells in vivo and in vitro.

Antel JP, Lin YH, Cui QL, Pernin F, Kennedy TE, Ludwin SK, Healy LM.

J Neuroimmunol. 2019 Jun 15;331:28-35. doi: 10.1016/j.jneuroim.2018.03.006. Epub 2018 Mar 13. Review.

PMID:
29566973
34.

The reality of "ghosts" in authorship of clinical trials in multiple sclerosis.

Antel J.

Ann Neurol. 2018 Apr;83(4):656-657. doi: 10.1002/ana.25199. No abstract available.

PMID:
29534308
35.

Effect of an vitamin D deficiency on depressive symptoms in child and adolescent psychiatric patients - a randomized controlled trial: study protocol.

Föcker M, Antel J, Grasemann C, Führer D, Timmesfeld N, Öztürk D, Peters T, Hinney A, Hebebrand J, Libuda L.

BMC Psychiatry. 2018 Mar 1;18(1):57. doi: 10.1186/s12888-018-1637-7.

36.

MSJ 2018-editorial comment.

Thompson AJ, Antel J, Carroll WM, Geurts J.

Mult Scler. 2018 Feb;24(2):90-91. doi: 10.1177/1352458518756517. No abstract available.

PMID:
29451441
37.

MerTK-mediated regulation of myelin phagocytosis by macrophages generated from patients with MS.

Healy LM, Jang JH, Won SY, Lin YH, Touil H, Aljarallah S, Bar-Or A, Antel JP.

Neurol Neuroimmunol Neuroinflamm. 2017 Oct 16;4(6):e402. doi: 10.1212/NXI.0000000000000402. eCollection 2017 Nov.

38.
39.

Corrigendum: Divergent Neuroinflammatory Regulation of Microglial TREM Expression and Involvement of NF-κB.

Owens R, Grabert K, Davies CL, Alfieri A, Antel JP, Healy LM, McColl BW.

Front Cell Neurosci. 2017 Aug 24;11:256. doi: 10.3389/fncel.2017.00256. eCollection 2017.

40.

α7 nicotinic acetylcholine receptor signaling modulates the inflammatory phenotype of fetal brain microglia: first evidence of interference by iron homeostasis.

Cortes M, Cao M, Liu HL, Moore CS, Durosier LD, Burns P, Fecteau G, Desrochers A, Barreiro LB, Antel JP, Frasch MG.

Sci Rep. 2017 Sep 6;7(1):10645. doi: 10.1038/s41598-017-09439-z.

41.

Low 25(OH)-vitamin D concentrations are associated with emotional and behavioral problems in German children and adolescents.

Husmann C, Frank M, Schmidt B, Jöckel KH, Antel J, Reissner V, Libuda L, Hebebrand J, Föcker M.

PLoS One. 2017 Aug 23;12(8):e0183091. doi: 10.1371/journal.pone.0183091. eCollection 2017.

42.

Distinct age and differentiation-state dependent metabolic profiles of oligodendrocytes under optimal and stress conditions.

Rao VTS, Khan D, Cui QL, Fuh SC, Hossain S, Almazan G, Multhaup G, Healy LM, Kennedy TE, Antel JP.

PLoS One. 2017 Aug 8;12(8):e0182372. doi: 10.1371/journal.pone.0182372. eCollection 2017.

43.

Reconstitution of the peripheral immune repertoire following withdrawal of fingolimod.

Ghadiri M, Fitz-Gerald L, Rezk A, Li R, Nyirenda M, Haegert D, Giacomini PS, Bar-Or A, Antel J.

Mult Scler. 2017 Aug;23(9):1225-1232. doi: 10.1177/1352458517713147.

PMID:
28749311
44.

Comparative morphology and phagocytic capacity of primary human adult microglia with time-lapse imaging.

Levtova N, Healy LM, Gonczi CMC, Stopnicki B, Blain M, Kennedy TE, Moore CS, Antel JP, Darlington PJ.

J Neuroimmunol. 2017 Sep 15;310:143-149. doi: 10.1016/j.jneuroim.2017.05.012. Epub 2017 May 22.

PMID:
28606377
45.

A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response.

Haenseler W, Sansom SN, Buchrieser J, Newey SE, Moore CS, Nicholls FJ, Chintawar S, Schnell C, Antel JP, Allen ND, Cader MZ, Wade-Martins R, James WS, Cowley SA.

Stem Cell Reports. 2017 Jun 6;8(6):1727-1742. doi: 10.1016/j.stemcr.2017.05.017.

46.

Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans.

Owen DR, Narayan N, Wells L, Healy L, Smyth E, Rabiner EA, Galloway D, Williams JB, Lehr J, Mandhair H, Peferoen LA, Taylor PC, Amor S, Antel JP, Matthews PM, Moore CS.

J Cereb Blood Flow Metab. 2017 Aug;37(8):2679-2690. doi: 10.1177/0271678X17710182. Epub 2017 May 22.

47.

Sublethal oligodendrocyte injury: A reversible condition in multiple sclerosis?

Cui QL, Khan D, Rone M, T S Rao V, Johnson RM, Lin YH, Bilodeau PA, Hall JA, Rodriguez M, Kennedy TE, Ludwin SK, Antel JP.

Ann Neurol. 2017 Jun;81(6):811-824. doi: 10.1002/ana.24944. Epub 2017 Jun 2.

PMID:
28470695
48.

iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases.

Abud EM, Ramirez RN, Martinez ES, Healy LM, Nguyen CHH, Newman SA, Yeromin AV, Scarfone VM, Marsh SE, Fimbres C, Caraway CA, Fote GM, Madany AM, Agrawal A, Kayed R, Gylys KH, Cahalan MD, Cummings BJ, Antel JP, Mortazavi A, Carson MJ, Poon WW, Blurton-Jones M.

Neuron. 2017 Apr 19;94(2):278-293.e9. doi: 10.1016/j.neuron.2017.03.042.

49.

Dimethyl fumarate-induced lymphopenia in MS due to differential T-cell subset apoptosis.

Ghadiri M, Rezk A, Li R, Evans A, Luessi F, Zipp F, Giacomini PS, Antel J, Bar-Or A.

Neurol Neuroimmunol Neuroinflamm. 2017 Mar 23;4(3):e340. doi: 10.1212/NXI.0000000000000340. eCollection 2017 May.

50.

Divergent Neuroinflammatory Regulation of Microglial TREM Expression and Involvement of NF-κB.

Owens R, Grabert K, Davies CL, Alfieri A, Antel JP, Healy LM, McColl BW.

Front Cell Neurosci. 2017 Mar 2;11:56. doi: 10.3389/fncel.2017.00056. eCollection 2017. Erratum in: Front Cell Neurosci. 2017 Aug 24;11:256.

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