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Items: 1 to 50 of 81

1.

Latest advances in aging research and drug discovery.

Bakula D, Ablasser A, Aguzzi A, Antebi A, Barzilai N, Bittner MI, Jensen MB, Calkhoven CF, Chen D, Grey ADNJ, Feige JN, Georgievskaya A, Gladyshev VN, Golato T, Gudkov AV, Hoppe T, Kaeberlein M, Katajisto P, Kennedy BK, Lal U, Martin-Villalba A, Moskalev AA, Ozerov I, Petr MA, Reason, Rubinsztein DC, Tyshkovskiy A, Vanhaelen Q, Zhavoronkov A, Scheibye-Knudsen M.

Aging (Albany NY). 2019 Nov 21;11(22):9971-9981. doi: 10.18632/aging.102487. Epub 2019 Nov 21.

2.

Cell cycle dynamics during diapause entry and exit in an annual killifish revealed by FUCCI technology.

Dolfi L, Ripa R, Antebi A, Valenzano DR, Cellerino A.

Evodevo. 2019 Nov 8;10:29. doi: 10.1186/s13227-019-0142-5. eCollection 2019.

3.

To help aging populations, classify organismal senescence.

Calimport SRG, Bentley BL, Stewart CE, Pawelec G, Scuteri A, Vinciguerra M, Slack C, Chen D, Harries LW, Marchant G, Fleming GA, Conboy M, Antebi A, Small GW, Gil J, Lakatta EG, Richardson A, Rosen C, Nikolich K, Wyss-Coray T, Steinman L, Montine T, de Magalhães JP, Campisi J, Church G.

Science. 2019 Nov 1;366(6465):576-578. doi: 10.1126/science.aay7319. No abstract available.

4.

Dietary sulfur amino acid restriction upregulates DICER to confer beneficial effects.

Guerra BA, Brandão BB, Pinto SS, Salgueiro WG, De-Souza EA, Reis FCG, Batista TM, Cavalcante-Silva V, D'Almeida V, Castilho BA, Carneiro EM, Antebi A, Festuccia WT, Mori MA.

Mol Metab. 2019 Nov;29:124-135. doi: 10.1016/j.molmet.2019.08.017. Epub 2019 Aug 28.

5.

A secreted microRNA disrupts autophagy in distinct tissues of Caenorhabditis elegans upon ageing.

Zhou Y, Wang X, Song M, He Z, Cui G, Peng G, Dieterich C, Antebi A, Jing N, Shen Y.

Nat Commun. 2019 Oct 23;10(1):4827. doi: 10.1038/s41467-019-12821-2.

6.

Pluronic gel-based burrowing assay for rapid assessment of neuromuscular health in C. elegans.

Lesanpezeshki L, Hewitt JE, Laranjeiro R, Antebi A, Driscoll M, Szewczyk NJ, Blawzdziewicz J, Lacerda CMR, Vanapalli SA.

Sci Rep. 2019 Oct 23;9(1):15246. doi: 10.1038/s41598-019-51608-9.

7.

Leptin signaling impairs macrophage defenses against Salmonella Typhimurium.

Fischer J, Gutièrrez S, Ganesan R, Calabrese C, Ranjan R, Cildir G, Hos NJ, Rybniker J, Wolke M, Fries JWU, Tergaonkar V, Plum G, Antebi A, Robinson N.

Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16551-16560. doi: 10.1073/pnas.1904885116. Epub 2019 Jul 26.

8.

The ideal position of the peritoneal dialysis catheter is not always ideal.

Tanasiychuk T, Selgas R, Kushnir D, Abd Elhalim M, Antebi A, Del Peso G, Bajo MA, Frajewicki V.

Int Urol Nephrol. 2019 Oct;51(10):1867-1872. doi: 10.1007/s11255-019-02177-3. Epub 2019 Jul 1.

PMID:
31264086
9.

Developmental Timing: Honey, I Reprogrammed the Kids.

Antebi A.

Curr Biol. 2019 Jun 3;29(11):R420-R422. doi: 10.1016/j.cub.2019.04.054.

PMID:
31163147
10.

RNA interference may result in unexpected phenotypes in Caenorhabditis elegans.

De-Souza EA, Camara H, Salgueiro WG, Moro RP, Knittel TL, Tonon G, Pinto S, Pinca APF, Antebi A, Pasquinelli AE, Massirer KB, Mori MA.

Nucleic Acids Res. 2019 May 7;47(8):3957-3969. doi: 10.1093/nar/gkz154.

11.

Suppression of autophagic activity by Rubicon is a signature of aging.

Nakamura S, Oba M, Suzuki M, Takahashi A, Yamamuro T, Fujiwara M, Ikenaka K, Minami S, Tabata N, Yamamoto K, Kubo S, Tokumura A, Akamatsu K, Miyazaki Y, Kawabata T, Hamasaki M, Fukui K, Sango K, Watanabe Y, Takabatake Y, Kitajima TS, Okada Y, Mochizuki H, Isaka Y, Antebi A, Yoshimori T.

Nat Commun. 2019 Feb 19;10(1):847. doi: 10.1038/s41467-019-08729-6.

12.

Comparison of ESI-MS/MS and APCI-MS methods for the quantification of folic acid analogs in C. elegans.

Annibal A, Tam H, Latza C, Antebi A.

J Mass Spectrom. 2019 Apr;54(4):316-327. doi: 10.1002/jms.4337.

PMID:
30675959
13.

Paradoxically normal location of peritoneal dialysis catheter.

Tanasiychuk T, Kushnir DA, Antebi A, Frajewicki V.

Kidney Int. 2019 Feb;95(2):470. doi: 10.1016/j.kint.2018.07.016. No abstract available.

PMID:
30665577
14.

Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance.

Tiku V, Kew C, Mehrotra P, Ganesan R, Robinson N, Antebi A.

Nat Commun. 2018 Sep 6;9(1):3607. doi: 10.1038/s41467-018-06051-1.

15.

Nucleolar Function in Lifespan Regulation.

Tiku V, Antebi A.

Trends Cell Biol. 2018 Aug;28(8):662-672. doi: 10.1016/j.tcb.2018.03.007. Epub 2018 May 17. Review.

PMID:
29779866
16.

Small nucleoli are a cellular hallmark of longevity.

Tiku V, Jain C, Raz Y, Nakamura S, Heestand B, Liu W, Späth M, Suchiman HED, Müller RU, Slagboom PE, Partridge L, Antebi A.

Nat Commun. 2017 Aug 30;8:16083. doi: 10.1038/ncomms16083.

17.

Larval crowding accelerates C. elegans development and reduces lifespan.

Ludewig AH, Gimond C, Judkins JC, Thornton S, Pulido DC, Micikas RJ, Döring F, Antebi A, Braendle C, Schroeder FC.

PLoS Genet. 2017 Apr 10;13(4):e1006717. doi: 10.1371/journal.pgen.1006717. eCollection 2017 Apr.

18.

LIN-28 balances longevity and germline stem cell number in Caenorhabditis elegans through let-7/AKT/DAF-16 axis.

Wang D, Hou L, Nakamura S, Su M, Li F, Chen W, Yan Y, Green CD, Chen D, Zhang H, Antebi A, Han JJ.

Aging Cell. 2017 Feb;16(1):113-124. doi: 10.1111/acel.12539. Epub 2016 Oct 11.

19.

Oral Supplementation of Glucosamine Fails to Alleviate Acute Kidney Injury in Renal Ischemia-Reperfusion Damage.

Johnsen M, Späth MR, Denzel MS, Göbel H, Kubacki T, Hoyer KJ, Hinze Y, Benzing T, Schermer B, Antebi A, Burst V, Müller RU.

PLoS One. 2016 Aug 24;11(8):e0161315. doi: 10.1371/journal.pone.0161315. eCollection 2016.

20.

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer.

Strong R, Miller RA, Antebi A, Astle CM, Bogue M, Denzel MS, Fernandez E, Flurkey K, Hamilton KL, Lamming DW, Javors MA, de Magalhães JP, Martinez PA, McCord JM, Miller BF, Müller M, Nelson JF, Ndukum J, Rainger GE, Richardson A, Sabatini DM, Salmon AB, Simpkins JW, Steegenga WT, Nadon NL, Harrison DE.

Aging Cell. 2016 Oct;15(5):872-84. doi: 10.1111/acel.12496. Epub 2016 Jun 16.

21.

Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals.

Nakamura S, Karalay Ö, Jäger PS, Horikawa M, Klein C, Nakamura K, Latza C, Templer SE, Dieterich C, Antebi A.

Nat Commun. 2016 Mar 22;7:10944. doi: 10.1038/ncomms10944.

22.

Mutation of C. elegans demethylase spr-5 extends transgenerational longevity.

Greer EL, Becker B, Latza C, Antebi A, Shi Y.

Cell Res. 2016 Feb;26(2):229-38. doi: 10.1038/cr.2015.148. Epub 2015 Dec 22.

23.

Nuclear receptor signal transduction in C. elegans.

Antebi A.

WormBook. 2015 Jun 9:1-49. doi: 10.1895/wormbook.1.64.2. Review.

24.

Interventions to Slow Aging in Humans: Are We Ready?

Longo VD, Antebi A, Bartke A, Barzilai N, Brown-Borg HM, Caruso C, Curiel TJ, de Cabo R, Franceschi C, Gems D, Ingram DK, Johnson TE, Kennedy BK, Kenyon C, Klein S, Kopchick JJ, Lepperdinger G, Madeo F, Mirisola MG, Mitchell JR, Passarino G, Rudolph KL, Sedivy JM, Shadel GS, Sinclair DA, Spindler SR, Suh Y, Vijg J, Vinciguerra M, Fontana L.

Aging Cell. 2015 Aug;14(4):497-510. doi: 10.1111/acel.12338. Epub 2015 Apr 22. Review.

25.

Co-chaperone p23 regulates C. elegans Lifespan in Response to Temperature.

Horikawa M, Sural S, Hsu AL, Antebi A.

PLoS Genet. 2015 Apr 1;11(4):e1005023. doi: 10.1371/journal.pgen.1005023. eCollection 2015 Apr.

26.

Hexosamine pathway and (ER) protein quality control.

Denzel MS, Antebi A.

Curr Opin Cell Biol. 2015 Apr;33:14-8. doi: 10.1016/j.ceb.2014.10.001. Epub 2014 Oct 28. Review.

PMID:
25463841
27.

An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology.

Fernandes de Abreu DA, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F, Cornils A, Regenass M, Neagu A, Ostojic I, Liu C, Cho Y, Sifoglu D, Shen Y, Fontana W, Lu H, Csikasz-Nagy A, Murphy CT, Antebi A, Blanc E, Apfeld J, Zhang Y, Alcedo J, Ch'ng Q.

PLoS Genet. 2014 Mar 27;10(3):e1004225. doi: 10.1371/journal.pgen.1004225. eCollection 2014 Mar.

28.

Hexosamine pathway metabolites enhance protein quality control and prolong life.

Denzel MS, Storm NJ, Gutschmidt A, Baddi R, Hinze Y, Jarosch E, Sommer T, Hoppe T, Antebi A.

Cell. 2014 Mar 13;156(6):1167-1178. doi: 10.1016/j.cell.2014.01.061.

29.

DRE-1/FBXO11-dependent degradation of BLMP-1/BLIMP-1 governs C. elegans developmental timing and maturation.

Horn M, Geisen C, Cermak L, Becker B, Nakamura S, Klein C, Pagano M, Antebi A.

Dev Cell. 2014 Mar 31;28(6):697-710. doi: 10.1016/j.devcel.2014.01.028. Epub 2014 Mar 6.

30.

A photocleavable masked nuclear-receptor ligand enables temporal control of C. elegans development.

Judkins JC, Mahanti P, Hoffman JB, Yim I, Antebi A, Schroeder FC.

Angew Chem Int Ed Engl. 2014 Feb 17;53(8):2110-3. doi: 10.1002/anie.201307465. Epub 2014 Jan 22. Erratum in: Angew Chem Int Ed Engl. 2014 May 12;53(20):4994.

31.

Aging Cell: open access to all.

Adams P, Antebi A, Cuervo AM, Kennedy B, Sedivy J.

Aging Cell. 2014 Feb;13(1):1. doi: 10.1111/acel.12187. No abstract available.

32.

Comparative metabolomics reveals endogenous ligands of DAF-12, a nuclear hormone receptor, regulating C. elegans development and lifespan.

Mahanti P, Bose N, Bethke A, Judkins JC, Wollam J, Dumas KJ, Zimmerman AM, Campbell SL, Hu PJ, Antebi A, Schroeder FC.

Cell Metab. 2014 Jan 7;19(1):73-83. doi: 10.1016/j.cmet.2013.11.024.

33.

Steroid regulation of C. elegans diapause, developmental timing, and longevity.

Antebi A.

Curr Top Dev Biol. 2013;105:181-212. doi: 10.1016/B978-0-12-396968-2.00007-5. Review.

PMID:
23962843
34.

Dietary restriction induced longevity is mediated by nuclear receptor NHR-62 in Caenorhabditis elegans.

Heestand BN, Shen Y, Liu W, Magner DB, Storm N, Meharg C, Habermann B, Antebi A.

PLoS Genet. 2013;9(7):e1003651. doi: 10.1371/journal.pgen.1003651. Epub 2013 Jul 25.

35.

The NHR-8 nuclear receptor regulates cholesterol and bile acid homeostasis in C. elegans.

Magner DB, Wollam J, Shen Y, Hoppe C, Li D, Latza C, Rottiers V, Hutter H, Antebi A.

Cell Metab. 2013 Aug 6;18(2):212-24. doi: 10.1016/j.cmet.2013.07.007.

36.

Regulation of the CRL4(Cdt2) ubiquitin ligase and cell-cycle exit by the SCF(Fbxo11) ubiquitin ligase.

Rossi M, Duan S, Jeong YT, Horn M, Saraf A, Florens L, Washburn MP, Antebi A, Pagano M.

Mol Cell. 2013 Mar 28;49(6):1159-66. doi: 10.1016/j.molcel.2013.02.004. Epub 2013 Mar 7.

37.

Aging Cell in 2012. Editorial.

Adams P, Antebi A, Cuervo AM, Kennedy B, Sedivy J.

Aging Cell. 2013 Feb;12(1):1. doi: 10.1111/acel.12037. No abstract available.

38.

A steroid receptor-microRNA switch regulates life span in response to signals from the gonad.

Shen Y, Wollam J, Magner D, Karalay O, Antebi A.

Science. 2012 Dec 14;338(6113):1472-6. doi: 10.1126/science.1228967.

39.

Regulation of longevity by the reproductive system.

Antebi A.

Exp Gerontol. 2013 Jul;48(7):596-602. doi: 10.1016/j.exger.2012.09.009. Epub 2012 Oct 11. Review.

40.

Hormonal signal amplification mediates environmental conditions during development and controls an irreversible commitment to adulthood.

Schaedel ON, Gerisch B, Antebi A, Sternberg PW.

PLoS Biol. 2012;10(4):e1001306. doi: 10.1371/journal.pbio.1001306. Epub 2012 Apr 10.

41.

A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity.

Wollam J, Magner DB, Magomedova L, Rass E, Shen Y, Rottiers V, Habermann B, Cummins CL, Antebi A.

PLoS Biol. 2012;10(4):e1001305. doi: 10.1371/journal.pbio.1001305. Epub 2012 Apr 10.

42.

Regulation of neuronal APL-1 expression by cholesterol starvation.

Wiese M, Antebi A, Zheng H.

PLoS One. 2012;7(2):e32038. doi: 10.1371/journal.pone.0032038. Epub 2012 Feb 21.

43.

The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity.

Wollam J, Magomedova L, Magner DB, Shen Y, Rottiers V, Motola DL, Mangelsdorf DJ, Cummins CL, Antebi A.

Aging Cell. 2011 Oct;10(5):879-84. doi: 10.1111/j.1474-9726.2011.00733.x. Epub 2011 Aug 7.

44.

Sterol regulation of metabolism, homeostasis, and development.

Wollam J, Antebi A.

Annu Rev Biochem. 2011;80:885-916. doi: 10.1146/annurev-biochem-081308-165917. Review.

45.

Cell and Growth Cone Migrations.

Antebi A, Norris CR, Hedgecock EM, Garriga G.

In: Riddle DL, Blumenthal T, Meyer BJ, Priess JR, editors. C. elegans II. 2nd edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 1997. No abstract available. Chapter 21.

46.

Intracellular trafficking and synaptic function of APL-1 in Caenorhabditis elegans.

Wiese M, Antebi A, Zheng H.

PLoS One. 2010 Sep 20;5(9). pii: e12790. doi: 10.1371/journal.pone.0012790.

47.

Nuclear hormone receptor regulation of microRNAs controls developmental progression.

Bethke A, Fielenbach N, Wang Z, Mangelsdorf DJ, Antebi A.

Science. 2009 Apr 3;324(5923):95-8. doi: 10.1126/science.1164899.

48.

Announcements from your Editorial Team.

Antebi A, Cuervo AM, Miller R, Sedivy J.

Aging Cell. 2009 Feb;8(1):1-1. No abstract available.

49.

Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development.

Bratic I, Hench J, Henriksson J, Antebi A, Bürglin TR, Trifunovic A.

Nucleic Acids Res. 2009 Apr;37(6):1817-28. doi: 10.1093/nar/gkp018. Epub 2009 Jan 30.

50.

A conserved endocrine mechanism controls the formation of dauer and infective larvae in nematodes.

Ogawa A, Streit A, Antebi A, Sommer RJ.

Curr Biol. 2009 Jan 13;19(1):67-71. doi: 10.1016/j.cub.2008.11.063. Epub 2008 Dec 24.

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