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Items: 46

1.

TMEM41B is a novel regulator of autophagy and lipid mobilization.

Moretti F, Bergman P, Dodgson S, Marcellin D, Claerr I, Goodwin JM, DeJesus R, Kang Z, Antczak C, Begue D, Bonenfant D, Graff A, Genoud C, Reece-Hoyes JS, Russ C, Yang Z, Hoffman GR, Mueller M, Murphy LO, Xavier RJ, Nyfeler B.

EMBO Rep. 2018 Sep;19(9). pii: e45889. doi: 10.15252/embr.201845889. Epub 2018 Aug 20.

PMID:
30126924
2.

How Phenotypic Screening Influenced Drug Discovery: Lessons from Five Years of Practice.

Haasen D, Schopfer U, Antczak C, Guy C, Fuchs F, Selzer P.

Assay Drug Dev Technol. 2017 Aug/Sep;15(6):239-246. doi: 10.1089/adt.2017.796. Epub 2017 Aug 11. Review.

PMID:
28800248
3.

Evaluation of Compound Optical Interference in High-Content Screening.

Ibáñez G, Calder PA, Radu C, Bhinder B, Shum D, Antczak C, Djaballah H.

SLAS Discov. 2018 Apr;23(4):321-329. doi: 10.1177/2472555217707725. Epub 2017 May 3.

PMID:
28467117
4.

ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells.

Wee B, Pietras A, Ozawa T, Bazzoli E, Podlaha O, Antczak C, Westermark B, Nelander S, Uhrbom L, Forsberg-Nilsson K, Djaballah H, Michor F, Holland EC.

Sci Rep. 2016 Jul 26;6:25956. doi: 10.1038/srep25956.

5.

Proteasome Addiction Defined in Ewing Sarcoma Is Effectively Targeted by a Novel Class of 19S Proteasome Inhibitors.

Shukla N, Somwar R, Smith RS, Ambati S, Munoz S, Merchant M, D'Arcy P, Wang X, Kobos R, Antczak C, Bhinder B, Shum D, Radu C, Yang G, Taylor BS, Ng CK, Weigelt B, Khodos I, de Stanchina E, Reis-Filho JS, Ouerfelli O, Linder S, Djaballah H, Ladanyi M.

Cancer Res. 2016 Aug 1;76(15):4525-34. doi: 10.1158/0008-5472.CAN-16-1040. Epub 2016 Jun 2.

6.

Azaphilones from an Acid Mine Extremophile Strain of a Pleurostomophora sp.

Stierle AA, Stierle DB, Girtsman T, Mou TC, Antczak C, Djaballah H.

J Nat Prod. 2015 Dec 24;78(12):2917-23. doi: 10.1021/acs.jnatprod.5b00519. Epub 2015 Dec 7.

7.

A High-Content Assay to Screen for Modulators of EGFR Function.

Antczak C, Djaballah H.

Methods Mol Biol. 2016;1360:97-106. doi: 10.1007/978-1-4939-3073-9_8.

PMID:
26501905
8.

Challenges and opportunities toward enabling phenotypic screening of complex and 3D cell models.

Horman SR, Hogan C, Delos Reyes K, Lo F, Antczak C.

Future Med Chem. 2015;7(4):513-25. doi: 10.4155/fmc.14.163. Review.

PMID:
25875876
9.

Long-term functional outcomes of distal hypospadias repair: a single center retrospective comparative study of TIPs, Mathieu and MAGPI.

Hueber PA, Antczak C, Abdo A, Franc-Guimond J, Barrieras D, Houle AM.

J Pediatr Urol. 2015 Apr;11(2):68.e1-7. doi: 10.1016/j.jpurol.2014.09.011. Epub 2015 Mar 4.

PMID:
25824882
10.

The burden of skeletal-related events in patients with prostate cancer and bone metastasis.

Roghmann F, Antczak C, McKay RR, Choueiri T, Hu JC, Kibel AS, Kim SP, Kowalczyk KJ, Menon M, Nguyen PL, Saad F, Sammon JD, Schmid M, Sukumar S, Sun M, Noldus J, Trinh QD.

Urol Oncol. 2015 Jan;33(1):17.e9-17.e18. doi: 10.1016/j.urolonc.2014.09.010. Epub 2014 Oct 30.

PMID:
25443265
11.

A 1536-well fluorescence polarization assay to screen for modulators of the MUSASHI family of RNA-binding proteins.

Minuesa G, Antczak C, Shum D, Radu C, Bhinder B, Li Y, Djaballah H, Kharas MG.

Comb Chem High Throughput Screen. 2014;17(7):596-609.

12.

Chemical & RNAi screening at MSKCC: a collaborative platform to discover & repurpose drugs to fight disease.

Bhinder B, Antczak C, Shum D, Radu C, Mahida JP, Liu-Sullivan N, Ibanez G, Raja BS, Calder PA, Djaballah H.

Comb Chem High Throughput Screen. 2014 May;17(4):298-318.

13.

Phomopsolides and related compounds from the alga-associated fungus, Penicillium clavigerum.

Stierle AA, Stierle DB, Mitman GG, Snyder S, Antczak C, Djaballah H.

Nat Prod Commun. 2014 Jan;9(1):87-90.

PMID:
24660471
14.

The health care burden of skeletal related events in patients with renal cell carcinoma and bone metastasis.

Antczak C, Trinh VQ, Sood A, Ravi P, Roghmann F, Trudeau V, Chang SL, Karakiewicz PI, Kibel AS, Krishna N, Nguyen PL, Saad F, Sammon JD, Sukumar S, Zorn KC, Sun M, Trinh QD.

J Urol. 2014 Jun;191(6):1678-84. doi: 10.1016/j.juro.2013.12.042. Epub 2013 Dec 30.

PMID:
24384157
15.

A high-content assay strategy for the identification and profiling of ABCG2 modulators in live cells.

Antczak C, Wee B, Radu C, Bhinder B, Holland EC, Djaballah H.

Assay Drug Dev Technol. 2014 Jan-Feb;12(1):28-42. doi: 10.1089/adt.2013.521. Epub 2013 Aug 30.

16.

A high content assay to assess cellular fitness.

Antczak C, Mahida JP, Singh C, Calder PA, Djaballah H.

Comb Chem High Throughput Screen. 2014 Jan;17(1):12-24.

17.

A synergetic screening approach with companion effector for combination therapy: application to retinoblastoma.

Mahida JP, Antczak C, Decarlo D, Champ KG, Francis JH, Marr B, Polans AS, Albert DM, Abramson DH, Djaballah H.

PLoS One. 2013;8(3):e59156. doi: 10.1371/journal.pone.0059156. Epub 2013 Mar 19.

18.

Combining integrated genomics and functional genomics to dissect the biology of a cancer-associated, aberrant transcription factor, the ASPSCR1-TFE3 fusion oncoprotein.

Kobos R, Nagai M, Tsuda M, Merl MY, Saito T, Laé M, Mo Q, Olshen A, Lianoglou S, Leslie C, Ostrovnaya I, Antczak C, Djaballah H, Ladanyi M.

J Pathol. 2013 Apr;229(5):743-754. doi: 10.1002/path.4158. Epub 2013 Mar 5.

19.

An arrayed genome-scale lentiviral-enabled short hairpin RNA screen identifies lethal and rescuer gene candidates.

Bhinder B, Antczak C, Ramirez CN, Shum D, Liu-Sullivan N, Radu C, Frattini MG, Djaballah H.

Assay Drug Dev Technol. 2013 Apr;11(3):173-90. doi: 10.1089/adt.2012.475. Epub 2012 Nov 30.

20.

A class of allosteric caspase inhibitors identified by high-throughput screening.

Feldman T, Kabaleeswaran V, Jang SB, Antczak C, Djaballah H, Wu H, Jiang X.

Mol Cell. 2012 Aug 24;47(4):585-95. doi: 10.1016/j.molcel.2012.06.007. Epub 2012 Jul 12.

21.

A high-content biosensor-based screen identifies cell-permeable activators and inhibitors of EGFR function: implications in drug discovery.

Antczak C, Mahida JP, Bhinder B, Calder PA, Djaballah H.

J Biomol Screen. 2012 Aug;17(7):885-99. doi: 10.1177/1087057112446174. Epub 2012 May 9.

22.

Domain-based biosensor assay to screen for epidermal growth factor receptor modulators in live cells.

Antczak C, Bermingham A, Calder P, Malkov D, Song K, Fetter J, Djaballah H.

Assay Drug Dev Technol. 2012 Feb;10(1):24-36. doi: 10.1089/adt.2011.423. Epub 2012 Jan 26.

23.

A high throughput scintillation proximity imaging assay for protein methyltransferases.

Ibanez G, Shum D, Blum G, Bhinder B, Radu C, Antczak C, Luo M, Djaballah H.

Comb Chem High Throughput Screen. 2012 Jun 1;15(5):359-71.

24.

Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase.

Antczak C, Shum D, Bassit B, Frattini MG, Li Y, de Stanchina E, Scheinberg DA, Djaballah H.

Bioorg Med Chem Lett. 2011 Aug 1;21(15):4528-32. doi: 10.1016/j.bmcl.2011.05.129. Epub 2011 Jun 12.

25.

Intra-arterial and oral digoxin therapy for retinoblastoma.

Patel M, Paulus YM, Gobin YP, Djaballah H, Marr B, Dunkel IJ, Brodie S, Antczak C, Folberg R, Abramson DH.

Ophthalmic Genet. 2011 Sep;32(3):147-50. doi: 10.3109/13816810.2010.544530. Epub 2011 Mar 29.

PMID:
21446853
26.

Validation of a high-content screening assay using whole-well imaging of transformed phenotypes.

Ramirez CN, Ozawa T, Takagi T, Antczak C, Shum D, Graves R, Holland EC, Djaballah H.

Assay Drug Dev Technol. 2011 Jun;9(3):247-61. doi: 10.1089/adt.2010.0342. Epub 2010 Dec 23.

27.

Cell viability assessment: toward content-rich platforms.

Ramirez CN, Antczak C, Djaballah H.

Expert Opin Drug Discov. 2010 Mar;5(3):223-33. doi: 10.1517/17460441003596685. Epub 2010 Jan 29.

28.

Structure-activity relationships of 6-(2,6-dichlorophenyl)-8-methyl-2-(phenylamino)pyrido[2,3-d]pyrimidin-7-ones: toward selective Abl inhibitors.

Antczak C, Veach DR, Ramirez CN, Minchenko MA, Shum D, Calder PA, Frattini MG, Clarkson B, Djaballah H.

Bioorg Med Chem Lett. 2009 Dec 15;19(24):6872-6. doi: 10.1016/j.bmcl.2009.10.085. Epub 2009 Oct 23.

29.

Live-cell imaging of caspase activation for high-content screening.

Antczak C, Takagi T, Ramirez CN, Radu C, Djaballah H.

J Biomol Screen. 2009 Sep;14(8):956-69. doi: 10.1177/1087057109343207. Epub 2009 Sep 2.

30.

Development and validation of a high-density fluorescence polarization-based assay for the trypanosoma RNA triphosphatase TbCet1.

Antczak C, Shum D, Radu C, Seshan VE, Djaballah H.

Comb Chem High Throughput Screen. 2009 Mar;12(3):258-68.

31.

Revisiting old drugs as novel agents for retinoblastoma: in vitro and in vivo antitumor activity of cardenolides.

Antczak C, Kloepping C, Radu C, Genski T, Müller-Kuhrt L, Siems K, de Stanchina E, Abramson DH, Djaballah H.

Invest Ophthalmol Vis Sci. 2009 Jul;50(7):3065-73. doi: 10.1167/iovs.08-3158. Epub 2009 Jan 17.

32.

Toward a prostate specific antigen-based prostate cancer diagnostic assay: preparation of keyhole limpet hemocyanin-conjugated normal and transformed prostate specific antigen fragments.

Dudkin VY, Miller JS, Dudkina AS, Antczak C, Scheinberg DA, Danishefsky SJ.

J Am Chem Soc. 2008 Oct 15;130(41):13598-607. doi: 10.1021/ja8028137. Epub 2008 Sep 18.

33.

Synthesis of antiproliferative Cephalotaxus esters and their evaluation against several human hematopoietic and solid tumor cell lines: uncovering differential susceptibilities to multidrug resistance.

Eckelbarger JD, Wilmot JT, Epperson MT, Thakur CS, Shum D, Antczak C, Tarassishin L, Djaballah H, Gin DY.

Chemistry. 2008;14(14):4293-306. doi: 10.1002/chem.200701998.

34.

A profiling platform for the identification of selective metalloprotease inhibitors.

Antczak C, Radu C, Djaballah H.

J Biomol Screen. 2008 Apr;13(4):285-94. doi: 10.1177/1087057108315877. Epub 2008 Mar 18.

35.

Synthesis and biological evaluation of a fluorine-18 derivative of dasatinib.

Veach DR, Namavari M, Pillarsetty N, Santos EB, Beresten-Kochetkov T, Lambek C, Punzalan BJ, Antczak C, Smith-Jones PM, Djaballah H, Clarkson B, Larson SM.

J Med Chem. 2007 Nov 15;50(23):5853-7. Epub 2007 Oct 23.

PMID:
17956080
36.

Tumor targeting with antibody-functionalized, radiolabeled carbon nanotubes.

McDevitt MR, Chattopadhyay D, Kappel BJ, Jaggi JS, Schiffman SR, Antczak C, Njardarson JT, Brentjens R, Scheinberg DA.

J Nucl Med. 2007 Jul;48(7):1180-9.

37.

High-throughput identification of inhibitors of human mitochondrial peptide deformylase.

Antczak C, Shum D, Escobar S, Bassit B, Kim E, Seshan VE, Wu N, Yang G, Ouerfelli O, Li YM, Scheinberg DA, Djaballah H.

J Biomol Screen. 2007 Jun;12(4):521-35. Epub 2007 Apr 13.

38.

Influence of the linker on the biodistribution and catabolism of actinium-225 self-immolative tumor-targeted isotope generators.

Antczak C, Jaggi JS, LeFave CV, Curcio MJ, McDevitt MR, Scheinberg DA.

Bioconjug Chem. 2006 Nov-Dec;17(6):1551-60.

39.

Natural killer cells license dendritic cell cross-presentation of B lymphoma cell--associated antigens.

Dao T, Gomez-Nunez M, Antczak C, Kappel B, Jaggi JS, Korontsvit T, Zakhaleva V, Scheinberg DA.

Clin Cancer Res. 2005 Dec 15;11(24 Pt 1):8763-72.

40.

A new human peptide deformylase inhibitable by actinonin.

Lee MD, Antczak C, Li Y, Sirotnak FM, Bornmann WG, Scheinberg DA.

Biochem Biophys Res Commun. 2003 Dec 12;312(2):309-15.

PMID:
14637138
41.

Reanalysis of the involvement of gamma-glutamyl transpeptidase in the cell activation process.

Antczak C, Karp DR, London RE, Bauvois B.

FEBS Lett. 2001 Nov 16;508(2):226-30.

42.

A new acivicin prodrug designed for tumor-targeted delivery.

Antczak C, Bauvois B, Monneret C, Florent JC.

Bioorg Med Chem. 2001 Nov;9(11):2843-8.

PMID:
11597464
43.

Transmembrane proteases as disease markers and targets for therapy.

Antczak C, De Meester I, Bauvois B.

J Biol Regul Homeost Agents. 2001 Apr-Jun;15(2):130-9. Review.

PMID:
11501970
44.

Targeting of acivicin prodrugs as antibody conjugates.

Antczak C, Bauvois B, Monneret C, Florent JC.

J Control Release. 2001 Jul 6;74(1-3):255-7.

PMID:
11489503
45.

Ectopeptidases in pathophysiology.

Antczak C, De Meester I, Bauvois B.

Bioessays. 2001 Mar;23(3):251-60. Review.

PMID:
11223882
46.

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