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Items: 1 to 50 of 192


Non-muscle Myosin II drives vesicle loss during human reticulocyte maturation.

Moura PL, Hawley BR, Mankelow TJ, Griffiths RE, Dobbe JGG, Streekstra GJ, Anstee DJ, Satchwell TJ, Toye AM.

Haematologica. 2018 Aug 3. pii: haematol.2018.199083. doi: 10.3324/haematol.2018.199083. [Epub ahead of print]


Enhancement of red blood cell transfusion compatibility using CRISPR-mediated erythroblast gene editing.

Hawksworth J, Satchwell TJ, Meinders M, Daniels DE, Regan F, Thornton NM, Wilson MC, Dobbe JG, Streekstra GJ, Trakarnsanga K, Heesom KJ, Anstee DJ, Frayne J, Toye AM.

EMBO Mol Med. 2018 Jun;10(6). pii: e8454. doi: 10.15252/emmm.201708454.


An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells.

Trakarnsanga K, Griffiths RE, Wilson MC, Blair A, Satchwell TJ, Meinders M, Cogan N, Kupzig S, Kurita R, Nakamura Y, Toye AM, Anstee DJ, Frayne J.

Nat Commun. 2017 Mar 14;8:14750. doi: 10.1038/ncomms14750.


Superior survival of ex vivo cultured human reticulocytes following transfusion into mice.

Kupzig S, Parsons SF, Curnow E, Anstee DJ, Blair A.

Haematologica. 2017 Mar;102(3):476-483. doi: 10.3324/haematol.2016.154443. Epub 2016 Dec 1.


The ins and outs of reticulocyte maturation revisited: The role of autophagy in sickle cell disease.

Mankelow TJ, Griffiths RE, Trompeter S, Flatt JF, Cogan NM, Massey EJ, Anstee DJ.

Autophagy. 2016;12(3):590-1. doi: 10.1080/15548627.2015.1125072.


Comparison of the Proteome of Adult and Cord Erythroid Cells, and Changes in the Proteome Following Reticulocyte Maturation.

Wilson MC, Trakarnsanga K, Heesom KJ, Cogan N, Green C, Toye AM, Parsons SF, Anstee DJ, Frayne J.

Mol Cell Proteomics. 2016 Jun;15(6):1938-46. doi: 10.1074/mcp.M115.057315. Epub 2016 Mar 22.


Unconventional cell death in erythroid cells.

Bruce LJ, Anstee DJ.

Blood. 2016 Jan 7;127(1):12-4. doi: 10.1182/blood-2015-11-677229. No abstract available.


Autophagic vesicles on mature human reticulocytes explain phosphatidylserine-positive red cells in sickle cell disease.

Mankelow TJ, Griffiths RE, Trompeter S, Flatt JF, Cogan NM, Massey EJ, Anstee DJ.

Blood. 2015 Oct 8;126(15):1831-4. doi: 10.1182/blood-2015-04-637702. Epub 2015 Aug 14.


Induction of adult levels of β-globin in human erythroid cells that intrinsically express embryonic or fetal globin by transduction with KLF1 and BCL11A-XL.

Trakarnsanga K, Wilson MC, Lau W, Singleton BK, Parsons SF, Sakuntanaga P, Kurita R, Nakamura Y, Anstee DJ, Frayne J.

Haematologica. 2014 Nov;99(11):1677-85. doi: 10.3324/haematol.2014.110155. Epub 2014 Aug 8.


Qualitative and quantitative comparison of the proteome of erythroid cells differentiated from human iPSCs and adult erythroid cells by multiplex TMT labelling and nanoLC-MS/MS.

Trakarnsanga K, Wilson MC, Griffiths RE, Toye AM, Carpenter L, Heesom KJ, Parsons SF, Anstee DJ, Frayne J.

PLoS One. 2014 Jul 14;9(7):e100874. doi: 10.1371/journal.pone.0100874. eCollection 2014.


Tetraspanins CD81 and CD82 facilitate α4β1-mediated adhesion of human erythroblasts to vascular cell adhesion molecule-1.

Spring FA, Griffiths RE, Mankelow TJ, Agnew C, Parsons SF, Chasis JA, Anstee DJ.

PLoS One. 2013 May 21;8(5):e62654. doi: 10.1371/journal.pone.0062654. Print 2013.


Autophagy facilitates organelle clearance during differentiation of human erythroblasts: evidence for a role for ATG4 paralogs during autophagosome maturation.

Betin VM, Singleton BK, Parsons SF, Anstee DJ, Lane JD.

Autophagy. 2013 Jun 1;9(6):881-93. doi: 10.4161/auto.24172. Epub 2013 Mar 18.


A novel GATA1 mutation (Stop414Arg) in a family with the rare X-linked blood group Lu(a-b-) phenotype and mild macrothrombocytic thrombocytopenia.

Singleton BK, Roxby DJ, Stirling JW, Spring FA, Wilson C, Poole J, Anstee DJ.

Br J Haematol. 2013 Apr;161(1):139-42. doi: 10.1111/bjh.12184. Epub 2012 Dec 24. No abstract available.


Identification of the components of a glycolytic enzyme metabolon on the human red blood cell membrane.

Puchulu-Campanella E, Chu H, Anstee DJ, Galan JA, Tao WA, Low PS.

J Biol Chem. 2013 Jan 11;288(2):848-58. doi: 10.1074/jbc.M112.428573. Epub 2012 Nov 13.


Blood group phenotypes resulting from mutations in erythroid transcription factors.

Singleton BK, Frayne J, Anstee DJ.

Curr Opin Hematol. 2012 Nov;19(6):486-93. doi: 10.1097/MOH.0b013e328358f92e. Review.


The ins and outs of human reticulocyte maturation: autophagy and the endosome/exosome pathway.

Griffiths RE, Kupzig S, Cogan N, Mankelow TJ, Betin VM, Trakarnsanga K, Massey EJ, Parsons SF, Anstee DJ, Lane JD.

Autophagy. 2012 Jul 1;8(7):1150-1. doi: 10.4161/auto.20648. Epub 2012 Jun 4.


Study of the D-- phenotype reveals erythrocyte membrane alterations in the absence of RHCE.

Flatt JF, Musa RH, Ayob Y, Hassan A, Asidin N, Yahya NM, Mathlouthi R, Thornton N, Anstee DJ, Bruce LJ.

Br J Haematol. 2012 Jul;158(2):262-273. doi: 10.1111/j.1365-2141.2012.09149.x. Epub 2012 May 10.


Maturing reticulocytes internalize plasma membrane in glycophorin A-containing vesicles that fuse with autophagosomes before exocytosis.

Griffiths RE, Kupzig S, Cogan N, Mankelow TJ, Betin VM, Trakarnsanga K, Massey EJ, Lane JD, Parsons SF, Anstee DJ.

Blood. 2012 Jun 28;119(26):6296-306. doi: 10.1182/blood-2011-09-376475. Epub 2012 Apr 6.


A cryptic mitochondrial targeting motif in Atg4D links caspase cleavage with mitochondrial import and oxidative stress.

Betin VM, MacVicar TD, Parsons SF, Anstee DJ, Lane JD.

Autophagy. 2012 Apr;8(4):664-76. doi: 10.4161/auto.19227. Epub 2012 Apr 1.


Ex-vivo generation of human red cells for transfusion.

Anstee DJ, Gampel A, Toye AM.

Curr Opin Hematol. 2012 May;19(3):163-9. doi: 10.1097/MOH.0b013e328352240a. Review.


Mutations in the second zinc finger of human EKLF reduce promoter affinity but give rise to benign and disease phenotypes.

Singleton BK, Lau W, Fairweather VS, Burton NM, Wilson MC, Parsons SF, Richardson BM, Trakarnsanga K, Brady RL, Anstee DJ, Frayne J.

Blood. 2011 Sep 15;118(11):3137-45. doi: 10.1182/blood-2011-04-349985. Epub 2011 Jul 21.


Critical band 3 multiprotein complex interactions establish early during human erythropoiesis.

Satchwell TJ, Bell AJ, Pellegrin S, Kupzig S, Ridgwell K, Daniels G, Anstee DJ, van den Akker E, Toye AM.

Blood. 2011 Jul 7;118(1):182-191. doi: 10.1182/blood-2010-10-314187. Epub 2011 Apr 28.


Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach.

Giardine B, Borg J, Higgs DR, Peterson KR, Philipsen S, Maglott D, Singleton BK, Anstee DJ, Basak AN, Clark B, Costa FC, Faustino P, Fedosyuk H, Felice AE, Francina A, Galanello R, Gallivan MV, Georgitsi M, Gibbons RJ, Giordano PC, Harteveld CL, Hoyer JD, Jarvis M, Joly P, Kanavakis E, Kollia P, Menzel S, Miller W, Moradkhani K, Old J, Papachatzopoulou A, Papadakis MN, Papadopoulos P, Pavlovic S, Perseu L, Radmilovic M, Riemer C, Satta S, Schrijver I, Stojiljkovic M, Thein SL, Traeger-Synodinos J, Tully R, Wada T, Waye JS, Wiemann C, Zukic B, Chui DH, Wajcman H, Hardison RC, Patrinos GP.

Nat Genet. 2011 Mar 20;43(4):295-301. doi: 10.1038/ng.785.


Aptamer therapy for SCD?

Anstee DJ.

Blood. 2011 Jan 13;117(2):379-80. doi: 10.1182/blood-2010-11-313858. No abstract available.


The functional importance of blood group-active molecules in human red blood cells.

Anstee DJ.

Vox Sang. 2011 Jan;100(1):140-9. doi: 10.1111/j.1423-0410.2010.01388.x. Review.


Production of erythroid cells from human embryonic stem cells (hESC) and human induced pluripotent stem cells (hiPS).

Anstee DJ.

Transfus Clin Biol. 2010 Sep;17(3):104-9. doi: 10.1016/j.tracli.2010.05.005. Epub 2010 Jul 23.


A new paradigm for pretransfusion testing with the same perennial limitations.

Westhoff CM, Anstee DJ.

Transfusion. 2010 Mar;50(3):520-1. doi: 10.1111/j.1537-2995.2010.02592.x. No abstract available.


The relationship between blood groups and disease.

Anstee DJ.

Blood. 2010 Jun 10;115(23):4635-43. doi: 10.1182/blood-2010-01-261859. Epub 2010 Mar 22. Review.


Analysis of the differential proteome of human erythroblasts during in vitro erythropoiesis by 2-D DIGE.

Richardson BM, Heesom KJ, Parsons SF, Anstee DJ, Frayne J.

Proteomics Clin Appl. 2009 Sep;3(9):1123-34. doi: 10.1002/prca.200900013. Epub 2009 Aug 26.


Red cell genotyping and the future of pretransfusion testing.

Anstee DJ.

Blood. 2009 Jul 9;114(2):248-56. doi: 10.1182/blood-2008-11-146860. Epub 2009 May 1. Review.


Lessons from the blood of sheep.

Anstee DJ.

Blood. 2008 Dec 1;112(12):4369. doi: 10.1182/blood-2008-08-173625. No abstract available.


Structure, function and significance of Rh proteins in red cells.

Burton NM, Anstee DJ.

Curr Opin Hematol. 2008 Nov;15(6):625-30. doi: 10.1097/MOH.0b013e328311f422. Review.


Adhesive activity of Lu glycoproteins is regulated by interaction with spectrin.

An X, Gauthier E, Zhang X, Guo X, Anstee DJ, Mohandas N, Chasis JA.

Blood. 2008 Dec 15;112(13):5212-8. doi: 10.1182/blood-2008-03-146068. Epub 2008 Sep 24.


New mutations in C1GALT1C1 in individuals with Tn positive phenotype.

Crew VK, Singleton BK, Green C, Parsons SF, Daniels G, Anstee DJ.

Br J Haematol. 2008 Aug;142(4):657-67. doi: 10.1111/j.1365-2141.2008.07215.x. Epub 2008 Jun 5.


alpha-Hemoglobin stabilizing protein is not a suitable marker for a screening test for variant Creutzfeldt-Jakob disease.

Appleford NE, Wilson K, Houston F, Bruce LJ, Morrison A, Bishop M, Chalmers K, Miele G, Massey E, Prowse C, Manson J, Will RG, Clinton M, MacGregor I, Anstee DJ.

Transfusion. 2008 Aug;48(8):1616-26. doi: 10.1111/j.1537-2995.2008.01759.x. Epub 2008 May 22.


Mutations in EKLF/KLF1 form the molecular basis of the rare blood group In(Lu) phenotype.

Singleton BK, Burton NM, Green C, Brady RL, Anstee DJ.

Blood. 2008 Sep 1;112(5):2081-8. doi: 10.1182/blood-2008-03-145672. Epub 2008 May 16.


Normal prion protein trafficking in cultured human erythroblasts.

Griffiths RE, Heesom KJ, Anstee DJ.

Blood. 2007 Dec 15;110(13):4518-25. Epub 2007 Sep 7.


The Laminin 511/521-binding site on the Lutheran blood group glycoprotein is located at the flexible junction of Ig domains 2 and 3.

Mankelow TJ, Burton N, Stefansdottir FO, Spring FA, Parsons SF, Pedersen JS, Oliveira CL, Lammie D, Wess T, Mohandas N, Chasis JA, Brady RL, Anstee DJ.

Blood. 2007 Nov 1;110(9):3398-406. Epub 2007 Jul 17.


Prion protein and the red cell.

Anstee DJ.

Curr Opin Hematol. 2007 May;14(3):210-4. Review.


Targeted gene deletion demonstrates that the cell adhesion molecule ICAM-4 is critical for erythroblastic island formation.

Lee G, Lo A, Short SA, Mankelow TJ, Spring F, Parsons SF, Yazdanbakhsh K, Mohandas N, Anstee DJ, Chasis JA.

Blood. 2006 Sep 15;108(6):2064-71. Epub 2006 May 11.


Goodbye to agglutination and all that?

Anstee DJ.

Transfusion. 2005 May;45(5):652-3. No abstract available.


The structure and function of Rh antigens-from monkeys to worms.

Anstee DJ.

Immunohematology. 1999;15(1):2-4. No abstract available.


CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin.

Karamatic Crew V, Burton N, Kagan A, Green CA, Levene C, Flinter F, Brady RL, Daniels G, Anstee DJ.

Blood. 2004 Oct 15;104(8):2217-23. Epub 2004 Jul 20.



Anstee DJ.

Vox Sang. 2004 Jul;87 Suppl1:13-4. Review. No abstract available.


Identification of critical amino-acid residues on the erythroid intercellular adhesion molecule-4 (ICAM-4) mediating adhesion to alpha V integrins.

Mankelow TJ, Spring FA, Parsons SF, Brady RL, Mohandas N, Chasis JA, Anstee DJ.

Blood. 2004 Feb 15;103(4):1503-8. Epub 2003 Oct 9.


Progress towards a blood test for vCJD?

Anstee DJ.

Vox Sang. 2002 Aug;83 Suppl 1:203-5. Review. No abstract available.


A band 3-based macrocomplex of integral and peripheral proteins in the RBC membrane.

Bruce LJ, Beckmann R, Ribeiro ML, Peters LL, Chasis JA, Delaunay J, Mohandas N, Anstee DJ, Tanner MJ.

Blood. 2003 May 15;101(10):4180-8. Epub 2003 Jan 16.


An N-terminal GFP tag does not alter the functional expression to the plasma membrane of red cell and kidney anion exchanger (AE1) in mammalian cells.

Beckmann R, Toye AM, Smythe JS, Anstee DJ, Tanner MJ.

Mol Membr Biol. 2002 Jul-Sep;19(3):187-200.


Novel secreted isoform of adhesion molecule ICAM-4: potential regulator of membrane-associated ICAM-4 interactions.

Lee G, Spring FA, Parsons SF, Mankelow TJ, Peters LL, Koury MJ, Mohandas N, Anstee DJ, Chasis JA.

Blood. 2003 Mar 1;101(5):1790-7. Epub 2002 Oct 24.


Epitope mapping of four novel CD44 monoclonal antibodies using surface plasmon resonance and soluble CD44.

Masson D, Vusio P, Loirat MJ, Spring F, Anstee DJ, Denis MG, Lustenberger P, Blanchard D.

Transfus Med. 2001 Dec;11(6):447-54.


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