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Items: 1 to 50 of 68

1.

A massively parallel 3' UTR reporter assay reveals relationships between nucleotide content, sequence conservation, and mRNA destabilization.

Litterman AJ, Kageyama R, Le Tonqueze O, Zhao W, Gagnon JD, Goodarzi H, Erle DJ, Ansel KM.

Genome Res. 2019 Jun;29(6):896-906. doi: 10.1101/gr.242552.118. Epub 2019 May 31.

PMID:
31152051
2.

The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research.

Das S; Extracellular RNA Communication Consortium, Ansel KM, Bitzer M, Breakefield XO, Charest A, Galas DJ, Gerstein MB, Gupta M, Milosavljevic A, McManus MT, Patel T, Raffai RL, Rozowsky J, Roth ME, Saugstad JA, Van Keuren-Jensen K, Weaver AM, Laurent LC.

Cell. 2019 Apr 4;177(2):231-242. doi: 10.1016/j.cell.2019.03.023. Review.

PMID:
30951667
3.

Increased Hematopoietic Extracellular RNAs and Vesicles in the Lung during Allergic Airway Responses.

Pua HH, Happ HC, Gray CJ, Mar DJ, Chiou NT, Hesse LE, Ansel KM.

Cell Rep. 2019 Jan 22;26(4):933-944.e4. doi: 10.1016/j.celrep.2019.01.002.

4.

Selective Export into Extracellular Vesicles and Function of tRNA Fragments during T Cell Activation.

Chiou NT, Kageyama R, Ansel KM.

Cell Rep. 2018 Dec 18;25(12):3356-3370.e4. doi: 10.1016/j.celrep.2018.11.073.

5.

Identification of Functionally Relevant microRNAs in the Regulation of Allergic Inflammation.

Fassett MS, Pua HH, Simpson LJ, Steiner DF, Ansel KM.

Methods Mol Biol. 2018;1799:341-351. doi: 10.1007/978-1-4939-7896-0_24.

6.

Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation.

Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, Woo JM, Mitros T, Ray GJ, Curie GL, Naddaf N, Chu JS, Ma H, Boyer E, Van Gool F, Huang H, Liu R, Tobin VR, Schumann K, Daly MJ, Farh KK, Ansel KM, Ye CJ, Greenleaf WJ, Anderson MS, Bluestone JA, Chang HY, Corn JE, Marson A.

Nature. 2018 Jul;559(7715):E13. doi: 10.1038/s41586-018-0227-7.

PMID:
29899441
7.

Bacterial biogeography of adult airways in atopic asthma.

Durack J, Huang YJ, Nariya S, Christian LS, Ansel KM, Beigelman A, Castro M, Dyer AM, Israel E, Kraft M, Martin RJ, Mauger DT, Rosenberg SR, King TS, White SR, Denlinger LC, Holguin F, Lazarus SC, Lugogo N, Peters SP, Smith LJ, Wechsler ME, Lynch SV, Boushey HA; National Heart, Lung and Blood Institute’s “AsthmaNet”.

Microbiome. 2018 Jun 9;6(1):104. doi: 10.1186/s40168-018-0487-3.

8.

MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation.

Singh PB, Pua HH, Happ HC, Schneider C, von Moltke J, Locksley RM, Baumjohann D, Ansel KM.

J Exp Med. 2017 Dec 4;214(12):3627-3643. doi: 10.1084/jem.20170545. Epub 2017 Nov 9.

9.

Discovery of stimulation-responsive immune enhancers with CRISPR activation.

Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, Woo JM, Mitros T, Ray GJ, Curie GL, Naddaf N, Chu JS, Ma H, Boyer E, Van Gool F, Huang H, Liu R, Tobin VR, Schumann K, Daly MJ, Farh KK, Ansel KM, Ye CJ, Greenleaf WJ, Anderson MS, Bluestone JA, Chang HY, Corn JE, Marson A.

Nature. 2017 Sep 7;549(7670):111-115. doi: 10.1038/nature23875. Epub 2017 Aug 30. Erratum in: Nature. 2018 Jul;559(7715):E13.

10.

A Distinct Inhibitory Function for miR-18a in Th17 Cell Differentiation.

Montoya MM, Maul J, Singh PB, Pua HH, Dahlström F, Wu N, Huang X, Ansel KM, Baumjohann D.

J Immunol. 2017 Jul 15;199(2):559-569. doi: 10.4049/jimmunol.1700170. Epub 2017 Jun 12.

11.

Small RNA Transfection in Primary Human Th17 Cells by Next Generation Electroporation.

Montoya MM, Ansel KM.

J Vis Exp. 2017 Apr 13;(122). doi: 10.3791/55546.

12.

Alternative splicing of interleukin-33 and type 2 inflammation in asthma.

Gordon ED, Simpson LJ, Rios CL, Ringel L, Lachowicz-Scroggins ME, Peters MC, Wesolowska-Andersen A, Gonzalez JR, MacLeod HJ, Christian LS, Yuan S, Barry L, Woodruff PG, Ansel KM, Nocka K, Seibold MA, Fahy JV.

Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8765-70. doi: 10.1073/pnas.1601914113. Epub 2016 Jul 18.

13.

MicroRNAs 24 and 27 Suppress Allergic Inflammation and Target a Network of Regulators of T Helper 2 Cell-Associated Cytokine Production.

Pua HH, Steiner DF, Patel S, Gonzalez JR, Ortiz-Carpena JF, Kageyama R, Chiou NT, Gallman A, de Kouchkovsky D, Jeker LT, McManus MT, Erle DJ, Ansel KM.

Immunity. 2016 Apr 19;44(4):821-32. doi: 10.1016/j.immuni.2016.01.003. Epub 2016 Feb 2.

14.

IFN-γ-Producing T-Helper 17.1 Cells Are Increased in Sarcoidosis and Are More Prevalent than T-Helper Type 1 Cells.

Ramstein J, Broos CE, Simpson LJ, Ansel KM, Sun SA, Ho ME, Woodruff PG, Bhakta NR, Christian L, Nguyen CP, Antalek BJ, Benn BS, Hendriks RW, van den Blink B, Kool M, Koth LL.

Am J Respir Crit Care Med. 2016 Jun 1;193(11):1281-91. doi: 10.1164/rccm.201507-1499OC.

15.

Biogenesis, delivery, and function of extracellular RNA.

Patton JG, Franklin JL, Weaver AM, Vickers K, Zhang B, Coffey RJ, Ansel KM, Blelloch R, Goga A, Huang B, L'Etoille N, Raffai RL, Lai CP, Krichevsky AM, Mateescu B, Greiner VJ, Hunter C, Voinnet O, McManus MT.

J Extracell Vesicles. 2015 Aug 28;4:27494. doi: 10.3402/jev.v4.27494. eCollection 2015.

16.

MicroRNA regulation of allergic inflammation and asthma.

Pua HH, Ansel KM.

Curr Opin Immunol. 2015 Oct;36:101-8. doi: 10.1016/j.coi.2015.07.006. Epub 2015 Aug 5. Review.

17.

mir-181a-1/b-1 Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell Function.

Schaffert SA, Loh C, Wang S, Arnold CP, Axtell RC, Newell EW, Nolan G, Ansel KM, Davis MM, Steinman L, Chen CZ.

J Immunol. 2015 Aug 15;195(4):1470-9. doi: 10.4049/jimmunol.1401587. Epub 2015 Jul 10.

18.

MicroRNA regulation of lymphocyte tolerance and autoimmunity.

Simpson LJ, Ansel KM.

J Clin Invest. 2015 Jun;125(6):2242-9. doi: 10.1172/JCI78090. Epub 2015 Jun 1. Review.

19.

Tracking early T follicular helper cell differentiation in vivo.

Baumjohann D, Ansel KM.

Methods Mol Biol. 2015;1291:27-38. doi: 10.1007/978-1-4939-2498-1_3.

20.

Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia.

Geng H, Hurtz C, Lenz KB, Chen Z, Baumjohann D, Thompson S, Goloviznina NA, Chen WY, Huan J, LaTocha D, Ballabio E, Xiao G, Lee JW, Deucher A, Qi Z, Park E, Huang C, Nahar R, Kweon SM, Shojaee S, Chan LN, Yu J, Kornblau SM, Bijl JJ, Ye BH, Ansel KM, Paietta E, Melnick A, Hunger SP, Kurre P, Tyner JW, Loh ML, Roeder RG, Druker BJ, Burger JA, Milne TA, Chang BH, Müschen M.

Cancer Cell. 2015 Mar 9;27(3):409-25. doi: 10.1016/j.ccell.2015.02.003.

21.

Induced miR-99a expression represses Mtor cooperatively with miR-150 to promote regulatory T-cell differentiation.

Warth SC, Hoefig KP, Hiekel A, Schallenberg S, Jovanovic K, Klein L, Kretschmer K, Ansel KM, Heissmeyer V.

EMBO J. 2015 May 5;34(9):1195-213. doi: 10.15252/embj.201489589. Epub 2015 Feb 23.

22.

The transcription factor NFAT promotes exhaustion of activated CD8⁺ T cells.

Martinez GJ, Pereira RM, Äijö T, Kim EY, Marangoni F, Pipkin ME, Togher S, Heissmeyer V, Zhang YC, Crotty S, Lamperti ED, Ansel KM, Mempel TR, Lähdesmäki H, Hogan PG, Rao A.

Immunity. 2015 Feb 17;42(2):265-278. doi: 10.1016/j.immuni.2015.01.006. Epub 2015 Feb 10.

23.

Editorial overview: Allergy and hypersensitivity.

Sperling AI, Ansel KM.

Curr Opin Immunol. 2014 Dec;31:ix-xi. No abstract available.

PMID:
25456768
24.

A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production.

Simpson LJ, Patel S, Bhakta NR, Choy DF, Brightbill HD, Ren X, Wang Y, Pua HH, Baumjohann D, Montoya MM, Panduro M, Remedios KA, Huang X, Fahy JV, Arron JR, Woodruff PG, Ansel KM.

Nat Immunol. 2014 Dec;15(12):1162-70. doi: 10.1038/ni.3026. Epub 2014 Nov 2.

25.

Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility.

Seumois G, Chavez L, Gerasimova A, Lienhard M, Omran N, Kalinke L, Vedanayagam M, Ganesan AP, Chawla A, Djukanović R, Ansel KM, Peters B, Rao A, Vijayanand P.

Nat Immunol. 2014 Aug;15(8):777-88. doi: 10.1038/ni.2937. Epub 2014 Jul 6.

26.

Eri1: a conserved enzyme at the crossroads of multiple RNA-processing pathways.

Thomas MF, L'Etoile ND, Ansel KM.

Trends Genet. 2014 Jul;30(7):298-307. doi: 10.1016/j.tig.2014.05.003. Epub 2014 Jun 12. Review.

27.

MicroRNA regulation of the germinal center response.

Baumjohann D, Ansel KM.

Curr Opin Immunol. 2014 Jun;28:6-11. doi: 10.1016/j.coi.2014.01.003. Epub 2014 Feb 14. Review.

28.

Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice.

Watchmaker PB, Lahl K, Lee M, Baumjohann D, Morton J, Kim SJ, Zeng R, Dent A, Ansel KM, Diamond B, Hadeiba H, Butcher EC.

Nat Immunol. 2014 Jan;15(1):98-108. doi: 10.1038/ni.2768. Epub 2013 Dec 1.

29.

MicroRNA-mediated regulation of T helper cell differentiation and plasticity.

Baumjohann D, Ansel KM.

Nat Rev Immunol. 2013 Sep;13(9):666-78. doi: 10.1038/nri3494. Epub 2013 Aug 2. Review.

30.

The microRNA cluster miR-17∼92 promotes TFH cell differentiation and represses subset-inappropriate gene expression.

Baumjohann D, Kageyama R, Clingan JM, Morar MM, Patel S, de Kouchkovsky D, Bannard O, Bluestone JA, Matloubian M, Ansel KM, Jeker LT.

Nat Immunol. 2013 Aug;14(8):840-8. doi: 10.1038/ni.2642. Epub 2013 Jun 30.

31.

Regulation of miRNA biogenesis and turnover in the immune system.

Bronevetsky Y, Ansel KM.

Immunol Rev. 2013 May;253(1):304-16. doi: 10.1111/imr.12059. Review.

32.

RNA regulation of the immune system.

Ansel KM.

Immunol Rev. 2013 May;253(1):5-11. doi: 10.1111/imr.12062. No abstract available.

33.

Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotype.

Baumjohann D, Preite S, Reboldi A, Ronchi F, Ansel KM, Lanzavecchia A, Sallusto F.

Immunity. 2013 Mar 21;38(3):596-605. doi: 10.1016/j.immuni.2012.11.020. Epub 2013 Mar 14.

34.

T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire.

Bronevetsky Y, Villarino AV, Eisley CJ, Barbeau R, Barczak AJ, Heinz GA, Kremmer E, Heissmeyer V, McManus MT, Erle DJ, Rao A, Ansel KM.

J Exp Med. 2013 Feb 11;210(2):417-32. doi: 10.1084/jem.20111717. Epub 2013 Feb 4.

35.

An integrated nano-scale approach to profile miRNAs in limited clinical samples.

Seumois G, Vijayanand P, Eisley CJ, Omran N, Kalinke L, North M, Ganesan AP, Simpson LJ, Hunkapiller N, Moltzahn F, Woodruff PG, Fahy JV, Erle DJ, Djukanovic R, Blelloch R, Ansel KM.

Am J Clin Exp Immunol. 2012 Nov 30;1(2):70-89.

36.

Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay.

Hoefig KP, Rath N, Heinz GA, Wolf C, Dameris J, Schepers A, Kremmer E, Ansel KM, Heissmeyer V.

Nat Struct Mol Biol. 2013 Jan;20(1):73-81. doi: 10.1038/nsmb.2450. Epub 2012 Dec 2.

PMID:
23202588
37.

Airway epithelial miRNA expression is altered in asthma.

Solberg OD, Ostrin EJ, Love MI, Peng JC, Bhakta NR, Hou L, Nguyen C, Solon M, Nguyen C, Barczak AJ, Zlock LT, Blagev DP, Finkbeiner WE, Ansel KM, Arron JR, Erle DJ, Woodruff PG.

Am J Respir Crit Care Med. 2012 Nov 15;186(10):965-74. doi: 10.1164/rccm.201201-0027OC. Epub 2012 Sep 6.

38.

Eri1 regulates microRNA homeostasis and mouse lymphocyte development and antiviral function.

Thomas MF, Abdul-Wajid S, Panduro M, Babiarz JE, Rajaram M, Woodruff P, Lanier LL, Heissmeyer V, Ansel KM.

Blood. 2012 Jul 5;120(1):130-42. doi: 10.1182/blood-2011-11-394072. Epub 2012 May 21.

39.

Interleukin-4 production by follicular helper T cells requires the conserved Il4 enhancer hypersensitivity site V.

Vijayanand P, Seumois G, Simpson LJ, Abdul-Wajid S, Baumjohann D, Panduro M, Huang X, Interlandi J, Djuretic IM, Brown DR, Sharpe AH, Rao A, Ansel KM.

Immunity. 2012 Feb 24;36(2):175-87. doi: 10.1016/j.immuni.2011.12.014. Epub 2012 Feb 9.

40.

MicroRNA-29 regulates T-box transcription factors and interferon-γ production in helper T cells.

Steiner DF, Thomas MF, Hu JK, Yang Z, Babiarz JE, Allen CD, Matloubian M, Blelloch R, Ansel KM.

Immunity. 2011 Aug 26;35(2):169-81. doi: 10.1016/j.immuni.2011.07.009. Epub 2011 Aug 4.

41.

Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development.

Baumjohann D, Okada T, Ansel KM.

J Immunol. 2011 Sep 1;187(5):2089-92. doi: 10.4049/jimmunol.1101393. Epub 2011 Jul 29.

42.

Induction and maintenance of IL-4 expression are regulated differently by the 3' enhancer in CD4 T cells.

Sofi MH, Qiao Y, Ansel KM, Kubo M, Chang CH.

J Immunol. 2011 Mar 1;186(5):2792-9. doi: 10.4049/jimmunol.1003353. Epub 2011 Jan 31.

43.

Construction of small RNA cDNA libraries for deep sequencing.

Thomas MF, Ansel KM.

Methods Mol Biol. 2010;667:93-111. doi: 10.1007/978-1-60761-811-9_7.

PMID:
20827529
44.

Six RNA viruses and forty-one hosts: viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate systems.

Parameswaran P, Sklan E, Wilkins C, Burgon T, Samuel MA, Lu R, Ansel KM, Heissmeyer V, Einav S, Jackson W, Doukas T, Paranjape S, Polacek C, dos Santos FB, Jalili R, Babrzadeh F, Gharizadeh B, Grimm D, Kay M, Koike S, Sarnow P, Ronaghi M, Ding SW, Harris E, Chow M, Diamond MS, Kirkegaard K, Glenn JS, Fire AZ.

PLoS Pathog. 2010 Feb 12;6(2):e1000764. doi: 10.1371/journal.ppat.1000764.

45.

Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA processing.

Ansel KM, Pastor WA, Rath N, Lapan AD, Glasmacher E, Wolf C, Smith LC, Papadopoulou N, Lamperti ED, Tahiliani M, Ellwart JW, Shi Y, Kremmer E, Rao A, Heissmeyer V.

Nat Struct Mol Biol. 2008 May;15(5):523-30. doi: 10.1038/nsmb.1417. Epub 2008 Apr 27.

46.
47.

The NFAT1 transcription factor is a repressor of cyclin A2 gene expression.

Carvalho LD, Teixeira LK, Carrossini N, Caldeira AT, Ansel KM, Rao A, Viola JP.

Cell Cycle. 2007 Jul 15;6(14):1789-95. Epub 2007 May 21.

PMID:
17637565
48.

Regulation of the germinal center response by microRNA-155.

Thai TH, Calado DP, Casola S, Ansel KM, Xiao C, Xue Y, Murphy A, Frendewey D, Valenzuela D, Kutok JL, Schmidt-Supprian M, Rajewsky N, Yancopoulos G, Rao A, Rajewsky K.

Science. 2007 Apr 27;316(5824):604-8.

49.

Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells.

Djuretic IM, Levanon D, Negreanu V, Groner Y, Rao A, Ansel KM.

Nat Immunol. 2007 Feb;8(2):145-53. Epub 2006 Dec 31.

PMID:
17195845
50.

Regulation of gene expression in mast cells: micro-rNA expression and chromatin structural analysis of cytokine genes.

Monticelli S, Ansel KM, Lee DU, Rao A.

Novartis Found Symp. 2005;271:179-87; discussion 187-90, 198-9. Review.

PMID:
16605135

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