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Items: 1 to 20 of 24

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1.

Anticancer Activity and Catalytic Potential of Ruthenium(II)-Arene Complexes with N,O-Donor Ligands.

Haghdoost MM, Guard J, Golbaghi G, Castonguay A.

Inorg Chem. 2018 Jul 2;57(13):7558-7567. doi: 10.1021/acs.inorgchem.8b00346. Epub 2018 Jun 11.

PMID:
29888595
2.

Reply to The small molecule CLP257 does not modify activity of the K+-Cl- co-transporter KCC2 but does potentiate GABAA receptor activity.

Gagnon M, Bergeron MJ, Perez-Sanchez J, Plasencia-Fernández I, Lorenzo LE, Godin AG, Castonguay A, Bonin RP, De Koninck Y.

Nat Med. 2017 Dec 7;23(12):1396-1398. doi: 10.1038/nm.4449. No abstract available.

PMID:
29216044
3.
4.

Peptide modification results in the formation of a dimer with a 60-fold enhanced antimicrobial activity.

Thamri A, Létourneau M, Djoboulian A, Chatenet D, Déziel E, Castonguay A, Perreault J.

PLoS One. 2017 Mar 15;12(3):e0173783. doi: 10.1371/journal.pone.0173783. eCollection 2017.

5.

Endocannabinoid signaling enhances visual responses through modulation of intracellular chloride levels in retinal ganglion cells.

Miraucourt LS, Tsui J, Gobert D, Desjardins JF, Schohl A, Sild M, Spratt P, Castonguay A, De Koninck Y, Marsh-Armstrong N, Wiseman PW, Ruthazer ES.

Elife. 2016 Aug 8;5. pii: e15932. doi: 10.7554/eLife.15932.

6.

Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine.

Taylor AM, Castonguay A, Ghogha A, Vayssiere P, Pradhan AA, Xue L, Mehrabani S, Wu J, Levitt P, Olmstead MC, De Koninck Y, Evans CJ, Cahill CM.

Neuropsychopharmacology. 2016 Mar;41(4):949-59. doi: 10.1038/npp.2015.221. Epub 2015 Jul 23.

7.

Microglia disrupt mesolimbic reward circuitry in chronic pain.

Taylor AM, Castonguay A, Taylor AJ, Murphy NP, Ghogha A, Cook C, Xue L, Olmstead MC, De Koninck Y, Evans CJ, Cahill CM.

J Neurosci. 2015 Jun 3;35(22):8442-50. doi: 10.1523/JNEUROSCI.4036-14.2015.

8.

Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain.

Ford A, Castonguay A, Cottet M, Little JW, Chen Z, Symons-Liguori AM, Doyle T, Egan TM, Vanderah TW, De Koninck Y, Tosh DK, Jacobson KA, Salvemini D.

J Neurosci. 2015 Apr 15;35(15):6057-67. doi: 10.1523/JNEUROSCI.4495-14.2015. Erratum in: J Neurosci. 2015 Jun 10;35(23):8971.

9.

[KCC2: a new therapeutical target for the treatment of neurological diseases].

Bergeron MJ, Castonguay A, De Koninck Y.

Med Sci (Paris). 2014 May;30(5):514-7. doi: 10.1051/medsci/20143005013. Epub 2014 Jun 13. French. No abstract available.

10.

Extended two-photon microscopy in live samples with Bessel beams: steadier focus, faster volume scans, and simpler stereoscopic imaging.

Thériault G, Cottet M, Castonguay A, McCarthy N, De Koninck Y.

Front Cell Neurosci. 2014 May 20;8:139. doi: 10.3389/fncel.2014.00139. eCollection 2014.

11.

Caspase-1 activity in microglia stimulated by pro-inflammagen nanocrystals.

Moquin A, Hutter E, Choi AO, Khatchadourian A, Castonguay A, Winnik FM, Maysinger D.

ACS Nano. 2013 Nov 26;7(11):9585-98. doi: 10.1021/nn404473g. Epub 2013 Oct 15.

PMID:
24107183
12.

Chloride extrusion enhancers as novel therapeutics for neurological diseases.

Gagnon M, Bergeron MJ, Lavertu G, Castonguay A, Tripathy S, Bonin RP, Perez-Sanchez J, Boudreau D, Wang B, Dumas L, Valade I, Bachand K, Jacob-Wagner M, Tardif C, Kianicka I, Isenring P, Attardo G, Coull JA, De Koninck Y.

Nat Med. 2013 Nov;19(11):1524-8. doi: 10.1038/nm.3356. Epub 2013 Oct 6.

13.

Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl⁻ homeostasis.

Ferrini F, Trang T, Mattioli TA, Laffray S, Del'Guidice T, Lorenzo LE, Castonguay A, Doyon N, Zhang W, Godin AG, Mohr D, Beggs S, Vandal K, Beaulieu JM, Cahill CM, Salter MW, De Koninck Y.

Nat Neurosci. 2013 Feb;16(2):183-92. doi: 10.1038/nn.3295. Epub 2013 Jan 6.

14.

New ruthenium(II)-letrozole complexes as anticancer therapeutics.

Castonguay A, Doucet C, Juhas M, Maysinger D.

J Med Chem. 2012 Oct 25;55(20):8799-806. doi: 10.1021/jm301103y. Epub 2012 Oct 4.

PMID:
22991922
15.

Thermosensitive dendrimer formulation for drug delivery at physiologically relevant temperatures.

Castonguay A, Wilson E, Al-Hajaj N, Petitjean L, Paoletti J, Maysinger D, Kakkar A.

Chem Commun (Camb). 2011 Nov 28;47(44):12146-8. doi: 10.1039/c1cc15354d. Epub 2011 Oct 12.

PMID:
21993413
16.

Efficacy of synaptic inhibition depends on multiple, dynamically interacting mechanisms implicated in chloride homeostasis.

Doyon N, Prescott SA, Castonguay A, Godin AG, Kröger H, De Koninck Y.

PLoS Comput Biol. 2011 Sep;7(9):e1002149. doi: 10.1371/journal.pcbi.1002149. Epub 2011 Sep 8.

17.

QRS widening and QT prolongation under bupropion: a unique cardiac electrophysiological profile.

Caillier B, Pilote S, Castonguay A, Patoine D, Ménard-Desrosiers V, Vigneault P, Hreiche R, Turgeon J, Daleau P, De Koninck Y, Simard C, Drolet B.

Fundam Clin Pharmacol. 2012 Oct;26(5):599-608. doi: 10.1111/j.1472-8206.2011.00953.x. Epub 2011 May 30.

PMID:
21623902
18.

Dendrimer templated construction of silver nanoparticles.

Castonguay A, Kakkar AK.

Adv Colloid Interface Sci. 2010 Oct 15;160(1-2):76-87. doi: 10.1016/j.cis.2010.07.006. Epub 2010 Jul 23. Review.

PMID:
20708163
19.

Combined Cu(I)-catalysed alkyne-azide cycloaddition and furan-maleimide Diels-Alder "click" chemistry approach to thermoresponsive dendrimers.

Vieyres A, Lam T, Gillet R, Franc G, Castonguay A, Kakkar A.

Chem Commun (Camb). 2010 Mar 21;46(11):1875-7. doi: 10.1039/b924888a. Epub 2010 Jan 13.

PMID:
20198238
20.

Coordination-mode control of bound nitrile radical complex reactivity: intercepting end-on nitrile-Mo(III) radicals at low temperature.

Germain ME, Temprado M, Castonguay A, Kryatova OP, Rybak-Akimova EV, Curley JJ, Mendiratta A, Tsai YC, Cummins CC, Prabhakar R, McDonough JE, Hoff CD.

J Am Chem Soc. 2009 Oct 28;131(42):15412-23. doi: 10.1021/ja905849a.

PMID:
19919164

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