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Items: 10

1.

Alternative splicing of the vitamin D receptor modulates target gene expression and promotes ligand-independent functions.

Annalora AJ, Jozic M, Marcus CB, Iversen PL.

Toxicol Appl Pharmacol. 2019 Feb 1;364:55-67. doi: 10.1016/j.taap.2018.12.009. Epub 2018 Dec 12.

PMID:
30552932
2.

A k-mer based transcriptomics approach for antisense drug discovery targeting the Ewing's family of tumors.

Annalora AJ, O'Neil S, Bushman JD, Summerton JE, Marcus CB, Iversen PL.

Oncotarget. 2018 Jul 17;9(55):30568-30586. doi: 10.18632/oncotarget.25736. eCollection 2018 Jul 17.

3.

Alternative Splicing in the Cytochrome P450 Superfamily Expands Protein Diversity to Augment Gene Function and Redirect Human Drug Metabolism.

Annalora AJ, Marcus CB, Iversen PL.

Drug Metab Dispos. 2017 Apr;45(4):375-389. doi: 10.1124/dmd.116.073254. Epub 2017 Feb 10. Review.

PMID:
28188297
4.

Potent antiproliferative effects of 25-hydroxy-16-ene-23-yne-vitamin D₃ that resists the catalytic activity of both CYP27B1 and CYP24A1.

Rhieu SY, Annalora AJ, LaPorta E, Welsh J, Itoh T, Yamamoto K, Sakaki T, Chen TC, Uskokovic MR, Reddy GS.

J Cell Biochem. 2014 Aug;115(8):1392-402. doi: 10.1002/jcb.24789.

PMID:
24535953
5.

Metabolic stability of 3-epi-1α,25-dihydroxyvitamin D3 over 1 α 25-dihydroxyvitamin D3: metabolism and molecular docking studies using rat CYP24A1.

Rhieu SY, Annalora AJ, Wang G, Flarakos CC, Gathungu RM, Vouros P, Sigüeiro R, Mouriño A, Schuster I, Palmore GT, Reddy GS.

J Cell Biochem. 2013 Oct;114(10):2293-305. doi: 10.1002/jcb.24576.

PMID:
23606409
6.

The novel purification and biochemical characterization of a reversible CYP24A1:adrenodoxin complex.

Hartfield KA, Stout CD, Annalora AJ.

J Steroid Biochem Mol Biol. 2013 Jul;136:47-53. doi: 10.1016/j.jsbmb.2012.11.001. Epub 2012 Nov 16. Review.

PMID:
23165146
7.

A new insight into the role of rat cytochrome P450 24A1 in metabolism of selective analogs of 1α,25-dihydroxyvitamin D₃.

Rhieu SY, Annalora AJ, Gathungu RM, Vouros P, Uskokovic MR, Schuster I, Palmore GT, Reddy GS.

Arch Biochem Biophys. 2011 May 1;509(1):33-43. doi: 10.1016/j.abb.2011.02.004. Epub 2011 Feb 19.

8.

Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1.

Mast N, Annalora AJ, Lodowski DT, Palczewski K, Stout CD, Pikuleva IA.

J Biol Chem. 2011 Feb 18;286(7):5607-13. doi: 10.1074/jbc.M110.188433. Epub 2010 Dec 15.

9.

Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism.

Annalora AJ, Goodin DB, Hong WX, Zhang Q, Johnson EF, Stout CD.

J Mol Biol. 2010 Feb 19;396(2):441-51. doi: 10.1016/j.jmb.2009.11.057. Epub 2009 Dec 1.

10.

Hybrid homology modeling and mutational analysis of cytochrome P450C24A1 (CYP24A1) of the Vitamin D pathway: insights into substrate specificity and membrane bound structure-function.

Annalora AJ, Bobrovnikov-Marjon E, Serda R, Pastuszyn A, Graham SE, Marcus CB, Omdahl JL.

Arch Biochem Biophys. 2007 Apr 15;460(2):262-73. Epub 2006 Dec 3.

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