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Items: 35


Activity of a novel 1,3-beta-D-glucan Synthase Inhibitor, Ibrexafungerp (formerly SCY-078), Against Candida glabrata.

Ghannoum M, Long L, Isham N, Hager C, Wilson R, Borroto-Esoda K, Barat S, Angulo D.

Antimicrob Agents Chemother. 2019 Sep 30. pii: AAC.01510-19. doi: 10.1128/AAC.01510-19. [Epub ahead of print]


In vitro activity of ibrexafungerp, a novel glucan synthase inhibitor against Candida glabrata isolates with FKS mutations.

Nunnally NS, Etienne KA, Angulo D, Lockhart SR, Berkow EL.

Antimicrob Agents Chemother. 2019 Sep 3. pii: AAC.01692-19. doi: 10.1128/AAC.01692-19. [Epub ahead of print]


MSG-10: a Phase 2 study of oral ibrexafungerp (SCY-078) following initial echinocandin therapy in non-neutropenic patients with invasive candidiasis.

Spec A, Pullman J, Thompson GR, Powderly WG, Tobin EH, Vazquez J, Wring SA, Angulo D, Helou S, Pappas PG; Mycoses Study Group .

J Antimicrob Chemother. 2019 Oct 1;74(10):3056-3062. doi: 10.1093/jac/dkz277.


Effects of amount and recurrence of leaf herbivory on the induction of direct and indirect defences in wild cotton.

Abdala-Roberts L, Reyes-Hernández M, Quijano-Medina T, Moreira X, Francisco M, Angulo DF, Parra-Tabla V, Virgen A, Rojas JC.

Plant Biol (Stuttg). 2019 Jun 25. doi: 10.1111/plb.13022. [Epub ahead of print]


A Novel 1,3-Beta-d-Glucan Inhibitor, Ibrexafungerp (Formerly SCY-078), Shows Potent Activity in the Lower pH Environment of Vulvovaginitis.

Larkin EL, Long L, Isham N, Borroto-Esoda K, Barat S, Angulo D, Wring S, Ghannoum M.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e02611-18. doi: 10.1128/AAC.02611-18. Print 2019 May.


Climate change and conservation in a warm North American desert: effect in shrubby plants.

Sosa V, Loera I, Angulo DF, Vásquez-Cruz M, Gándara E.

PeerJ. 2019 Mar 7;7:e6572. doi: 10.7717/peerj.6572. eCollection 2019.


Identification of Preoperative Language Tracts for Intrinsic Frontotemporal Diseases: A Pilot Reconstruction Algorithm in a Middle-Income Country.

Ordóñez-Rubiano EG, Valderrama-Arias FA, Forbes JA, Johnson JM, Younus I, Marín-Muñoz JH, Sánchez-Montaño M, Angulo DA, Cifuentes-Lobelo HA, Cortes-Lozano W, Pedraza-Ciro MC, Bello-Dávila ML, Patiño-Gómez JG, Ordóñez-Mora EG.

World Neurosurg. 2019 May;125:e729-e742. doi: 10.1016/j.wneu.2019.01.163. Epub 2019 Feb 5.


SCY-078, a Novel Fungicidal Agent, Demonstrates Distribution to Tissues Associated with Fungal Infections during Mass Balance Studies with Intravenous and Oral [14C]SCY-078 in Albino and Pigmented Rats.

Wring S, Borroto-Esoda K, Solon E, Angulo D.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e02119-18. doi: 10.1128/AAC.02119-18. Print 2019 Feb.


Prevalence of eosinophilic esophagitis: A multicenter study on a pediatric population evaluated at thirty-six Latin American gastroenterology centers.

Pierre R, Vieira M, Vázquez R, Ninomiya I, Messere G, Daza W, Dadan S, Higuera M, Sifontes L, Harris P, Gana JC, Rodríguez M, Vasquez M, González M, Rivera J, Gonzales J, Angulo D, Cetraro MD, Del Compare M, López K, Navarro D, Calva R, Wagener M, Zablah R, Carias A, Calderón O, Vera-Chamorro JF, Toca MC, Dewaele MR, Iglesias C, Delgado L, León K, Hassan I, Ussher F, Follett F, Bernedo V, Grinblat V, Agüero N, Oviedo C, García AG, Salazar A, Coello P, Furnes R, Menchaca M, Fernández M, Khoury A, Rojo C, Fernández S, Morao C.

Rev Gastroenterol Mex. 2018 Oct 3. pii: S0375-0906(18)30163-0. doi: 10.1016/j.rgmx.2018.08.001. [Epub ahead of print] English, Spanish.


The Hyperhidrosis Disease Severity Measure-Axillary: Conceptualization and Development of Item Content.

Kirsch BM, Burke L, Hobart J, Angulo D, Walker PS.

J Drugs Dermatol. 2018 Jul 1;17(7):707-714.


Clinical Pharmacokinetics and Drug-Drug Interaction Potential for Coadministered SCY-078, an Oral Fungicidal Glucan Synthase Inhibitor, and Tacrolimus.

Wring S, Murphy G, Atiee G, Corr C, Hyman M, Willett M, Angulo D.

Clin Pharmacol Drug Dev. 2019 Jan;8(1):60-69. doi: 10.1002/cpdd.588. Epub 2018 Jun 27.


Evaluation of the Antifungal Activity of the Novel Oral Glucan Synthase Inhibitor SCY-078, Singly and in Combination, for the Treatment of Invasive Aspergillosis.

Ghannoum M, Long L, Larkin EL, Isham N, Sherif R, Borroto-Esoda K, Barat S, Angulo D.

Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e00244-18. doi: 10.1128/AAC.00244-18. Print 2018 Jun.


De Novo Acquisition of Resistance to SCY-078 in Candida glabrata Involves FKS Mutations That both Overlap and Are Distinct from Those Conferring Echinocandin Resistance.

Jiménez-Ortigosa C, Perez WB, Angulo D, Borroto-Esoda K, Perlin DS.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00833-17. doi: 10.1128/AAC.00833-17. Print 2017 Sep.


Long-term attention deficits combined with subcortical and cortical structural central nervous system alterations in young adults born small for gestational age.

Suffren S, Angulo D, Ding Y, Reyes P, Marin J, Hernandez JT, Charpak N, Lodygensky GA.

Early Hum Dev. 2017 Jul;110:44-49. doi: 10.1016/j.earlhumdev.2017.04.016. Epub 2017 May 23.


[Gastrointestinal bleeding in newborn with hookworm, National Hospital San Bartolome. Case report].

Valdivieso P, Cetraro D, Angulo D.

Rev Gastroenterol Peru. 2017 Jan-Mar;37(1):82-86. Spanish.


In Vitro Activity of a Novel Glucan Synthase Inhibitor, SCY-078, against Clinical Isolates of Candida auris.

Berkow EL, Angulo D, Lockhart SR.

Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e00435-17. doi: 10.1128/AAC.00435-17. Print 2017 Jul. No abstract available.


The Emerging Pathogen Candida auris: Growth Phenotype, Virulence Factors, Activity of Antifungals, and Effect of SCY-078, a Novel Glucan Synthesis Inhibitor, on Growth Morphology and Biofilm Formation.

Larkin E, Hager C, Chandra J, Mukherjee PK, Retuerto M, Salem I, Long L, Isham N, Kovanda L, Borroto-Esoda K, Wring S, Angulo D, Ghannoum M.

Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e02396-16. doi: 10.1128/AAC.02396-16. Print 2017 May.


Colonization in North American Arid Lands: The Journey of Agarito (Berberis trifoliolata) Revealed by Multilocus Molecular Data and Packrat Midden Fossil Remains.

Angulo DF, Amarilla LD, Anton AM, Sosa V.

PLoS One. 2017 Feb 1;12(2):e0168933. doi: 10.1371/journal.pone.0168933. eCollection 2017.


Preclinical Pharmacokinetics and Pharmacodynamic Target of SCY-078, a First-in-Class Orally Active Antifungal Glucan Synthesis Inhibitor, in Murine Models of Disseminated Candidiasis.

Wring SA, Randolph R, Park S, Abruzzo G, Chen Q, Flattery A, Garrett G, Peel M, Outcalt R, Powell K, Trucksis M, Angulo D, Borroto-Esoda K.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02068-16. doi: 10.1128/AAC.02068-16. Print 2017 Apr.


SCY-078 Is Fungicidal against Candida Species in Time-Kill Studies.

Scorneaux B, Angulo D, Borroto-Esoda K, Ghannoum M, Peel M, Wring S.

Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e01961-16. doi: 10.1128/AAC.01961-16. Print 2017 Mar.


A Multi-facetted Visual Analytics Tool for Exploratory Analysis of Human Brain and Function Datasets.

Angulo DA, Schneider C, Oliver JH, Charpak N, Hernandez JT.

Front Neuroinform. 2016 Aug 23;10:36. doi: 10.3389/fninf.2016.00036. eCollection 2016.


Rehabilitación de la alimentación por vía oral en niños con enfermedades respiratorias crónicas y nutrición enteral prolongada.

Angulo D, Bustos E, Sánchez A, Barja S.

Nutr Hosp. 2016 Jul 19;33(4):368. doi: 10.20960/nh.368. Spanish.


Munroa argentina, a Grass of the South American Transition Zone, Survived the Andean Uplift, Aridification and Glaciations of the Quaternary.

Amarilla LD, Anton AM, Chiapella JO, Manifesto MM, Angulo DF, Sosa V.

PLoS One. 2015 Jun 25;10(6):e0128559. doi: 10.1371/journal.pone.0128559. eCollection 2015.


Dynamics and forecast in a simple model of sustainable development for rural populations.

Angulo D, Angulo F, Olivar G.

Bull Math Biol. 2015 Feb;77(2):368-89. doi: 10.1007/s11538-014-9934-x. Epub 2014 Mar 12.


Predictive value of MicroRNAs in the progression of barrett esophagus to adenocarcinoma in a long-term follow-up study.

Revilla-Nuin B, Parrilla P, Lozano JJ, de Haro LF, Ortiz A, Martínez C, Munitiz V, de Angulo DR, Bermejo J, Molina J, Cayuela ML, Yélamos J.

Ann Surg. 2013 May;257(5):886-93. doi: 10.1097/SLA.0b013e31826ddba6.


[Human and professional aspects of Mr. Pedro Cifuentes Díaz (1881-1960)].

Angulo D, Pérez-Albacete M, Angulo JC.

Actas Urol Esp. 2012 May;36(5):312-9. doi: 10.1016/j.acuro.2012.01.003. Epub 2012 Mar 7. Spanish.


Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock?

Hernandez G, Castro R, Romero C, de la Hoz C, Angulo D, Aranguiz I, Larrondo J, Bujes A, Bruhn A.

J Crit Care. 2011 Aug;26(4):435.e9-14. doi: 10.1016/j.jcrc.2010.09.007. Epub 2010 Dec 3.


Synchronous vs asynchronous chain motion in alpha-synuclein contact dynamics.

Urie KG, Angulo D, Lee JC, Kozak JJ, Gray HB, Winkler JR.

J Phys Chem B. 2009 Jan 15;113(2):522-30. doi: 10.1021/jp806727e.


Pharmacokinetics of oral posaconazole in neutropenic patients receiving chemotherapy for acute myelogenous leukemia or myelodysplastic syndrome.

Krishna G, AbuTarif M, Xuan F, Martinho M, Angulo D, Cornely OA.

Pharmacotherapy. 2008 Oct;28(10):1223-32. doi: 10.1592/phco.28.10.1223.


Phosphoprotein profiling by PA-GeLC-MS/MS.

Kristjansdottir K, Wolfgeher D, Lucius N, Angulo DS, Kron SJ.

J Proteome Res. 2008 Jul;7(7):2812-24. doi: 10.1021/pr700816k. Epub 2008 May 30.


Investigating quantitation of phosphorylation using MALDI-TOF mass spectrometry.

Parker L, Engel-Hall A, Drew K, Steinhardt G, Helseth DL Jr, Jabon D, McMurry T, Angulo DS, Kron SJ.

J Mass Spectrom. 2008 Apr;43(4):518-27.


Use of Postoperative TENS and Continuous Passive Motion Following Total Knee Replacement.

Angulo DL, Colwell CW.

J Orthop Sports Phys Ther. 1990;11(12):599-604.


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